Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 229918561

GI number: 229918561

Start: 2811740

End: 2812213

Strand: Direct

Name: lspA [H]

Synonym: EAT1b_2848

Alternate gene names: 229918561

Gene position: 2811740-2812213 (Clockwise)

Preceding gene: 229918560

Following gene: 229918562

Centisome position: 93.73

GC content: 45.78

Gene sequence:

>474_bases
ATGAAACGATATTATGGATTGGCGCTCATCTTGATTTTGATCGATCAACTCACAAAATGGGTGGTCGTTCAGACGATGAC
AATTGGTCAATCGATTGAAGTCATCCCGAACTTGTTATATTGGACGTCCTACCGCAACAAAGGAGCGGCTTGGGGGATGT
TAGAAGGACAGATGGCGTTCTTCTTTATCATCACCATCCTCGTCGTTGCCGGACTCGTTTACTTCTTGCACAAAGAAGTG
AACGGCTATCAGCTCCTCGGATATAGTGTCGGATTACTGTTGGCCGGTGCCATCGGTAACTTTATCGATCGCTTGTTCCG
GGGCGAAGTCGTCGACTTTGTCGATACGTATCCGTTCGGATACAACTTCCCGATCTTTAACGTGGCCGATATGGCACTCA
CATTCGGTGTCATCTTGATGGTCATCGGGATTTTATTTGAAGAAAAATTACACAAAGAAAGGGGACAATCGTAA

Upstream 100 bases:

>100_bases
GCATCCAGAGCTTTGCCCGCGCTGTGCATCAGTAATCGGTTAAGACGAACCGGAGTGGCGTCCCCACTCCGGTTTCTTAA
CGGCTTGAAAGGAGACGCAT

Downstream 100 bases:

>100_bases
TGGAATCGTATACTTTTGTCGCCGATGAAAAGGCAAGGATTGATAAGTGGGTCAGTGACCGTGGTGAATGGTCACGCTCG
CAAGTACAGGAATGGATCAA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKRYYGLALILILIDQLTKWVVVQTMTIGQSIEVIPNLLYWTSYRNKGAAWGMLEGQMAFFFIITILVVAGLVYFLHKEV
NGYQLLGYSVGLLLAGAIGNFIDRLFRGEVVDFVDTYPFGYNFPIFNVADMALTFGVILMVIGILFEEKLHKERGQS

Sequences:

>Translated_157_residues
MKRYYGLALILILIDQLTKWVVVQTMTIGQSIEVIPNLLYWTSYRNKGAAWGMLEGQMAFFFIITILVVAGLVYFLHKEV
NGYQLLGYSVGLLLAGAIGNFIDRLFRGEVVDFVDTYPFGYNFPIFNVADMALTFGVILMVIGILFEEKLHKERGQS
>Mature_157_residues
MKRYYGLALILILIDQLTKWVVVQTMTIGQSIEVIPNLLYWTSYRNKGAAWGMLEGQMAFFFIITILVVAGLVYFLHKEV
NGYQLLGYSVGLLLAGAIGNFIDRLFRGEVVDFVDTYPFGYNFPIFNVADMALTFGVILMVIGILFEEKLHKERGQS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=156, Percent_Identity=30.1282051282051, Blast_Score=73, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17816; Mature: 17816

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYYGLALILILIDQLTKWVVVQTMTIGQSIEVIPNLLYWTSYRNKGAAWGMLEGQMAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FFIITILVVAGLVYFLHKEVNGYQLLGYSVGLLLAGAIGNFIDRLFRGEVVDFVDTYPFG
HHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
YNFPIFNVADMALTFGVILMVIGILFEEKLHKERGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRYYGLALILILIDQLTKWVVVQTMTIGQSIEVIPNLLYWTSYRNKGAAWGMLEGQMAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FFIITILVVAGLVYFLHKEVNGYQLLGYSVGLLLAGAIGNFIDRLFRGEVVDFVDTYPFG
HHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
YNFPIFNVADMALTFGVILMVIGILFEEKLHKERGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]