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The map label for this gene is murG

Identifier: 229918550

GI number: 229918550

Start: 2800543

End: 2801619

Strand: Direct

Name: murG

Synonym: EAT1b_2837

Alternate gene names: 229918550

Gene position: 2800543-2801619 (Clockwise)

Preceding gene: 229918549

Following gene: 229918551

Centisome position: 93.35

GC content: 52.18

Gene sequence:

>1077_bases
ATGAAAATCATGATTTCTGGTGGTGGTACCGGTGGTCATATTTATCCAGCACTCGCATTGATTGAAACGCTAAAAAAACG
TCACCCGGATTTACAGGTACAATATATCGGGACGGAGAATGGGTTAGAAGCCGATCTCGTACCGCGAGCCGGTGTCCCGT
TCAAGTCGATTCAAATCGCAGGTCTGAAGCGTTCCCTTTCACTCGAGAACGTGAAGACAGCCTACTGGTTTTTGAAAGCC
GTTCGGGCATTGAAAAAAGACATGGCGGCGTTTAAGCCGGACGTCGTGATTGGGACGGGTGGTTTCGTATCCGGCCCCGT
CGTCTATACGGCACAACAGCTTGGGATCCCCACGATTCTGCATGAACAAAACAGTATCCCAGGATTAACTAACAAATTCT
TATCGAAGAAAGCCGATCGGGTTGCCCTCTCGTTCAAAGGCTCAGATGTCCATTTCCCGGGTGCGAACGTTCGCTTGATT
GGAAACCCGCGTGGTAGCGAAGTCTTGCAAACGGAAGTCGATGAAGCGTCCGTCCGCGAACAGTATCGTTTAGATGACCG
TCCGATCGTCTTGGTGTATGGTGGGAGCCGCGGAGCCGAGGCCATCAACCGAGCGGTCGTGGAAGCGATCCCGTCGCTCT
CAGAATTGCCAATCAACGTCCTTTACGTCACGGGGAAAGTGCATTTCGATGCGGTGTCGAAACAGGCGCCATCTTCTGAC
AATGTACACATCCATCCATACGTGTACGATATGCCATCTTTACTCGCCTGTACGTCACTCGTCATCTCACGAGCTGGCGC
TTCGACGATTTCAGAATTGACCGCCCTTGGTTTACCGAGCATTTTGGTACCTAGTCCGTACGTGACAGCTGACCATCAAA
CGAAAAATGCTTCGGCCCTCGTCGAGAACGGGGCGGCCCTCCTTGTGAAAGAAGAGGCGTTGACGGGTGTTACGCTCGTA
GAAGCGATTCGTCAAGCACTCGAACAGCGTGATGAGATGGCGAACGCATCGCGTGCACTCGGTTTCCCGGACGCGTCAGA
TGCATTGGCCGACCTGGTAGAAGAAGTCATTCAATAA

Upstream 100 bases:

>100_bases
TACTCTCACCCGCTTGTGCTAGCTGGGATCAATTTAAAACGTTTGAAGAACGAGGCGAGCAGTTCGTTCAACTCGTCCGT
TCATATGAGGAGGCGAACCG

Downstream 100 bases:

>100_bases
AGGAGTAGAACCCGATGGAACCAAGCCAACAAACGGTACGTAGTCTCGAAGACCGTATTCCATACATGAAAAAACAACGG
CGTAAAAAAGCGAACCGTCG

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKIMISGGGTGGHIYPALALIETLKKRHPDLQVQYIGTENGLEADLVPRAGVPFKSIQIAGLKRSLSLENVKTAYWFLKA
VRALKKDMAAFKPDVVIGTGGFVSGPVVYTAQQLGIPTILHEQNSIPGLTNKFLSKKADRVALSFKGSDVHFPGANVRLI
GNPRGSEVLQTEVDEASVREQYRLDDRPIVLVYGGSRGAEAINRAVVEAIPSLSELPINVLYVTGKVHFDAVSKQAPSSD
NVHIHPYVYDMPSLLACTSLVISRAGASTISELTALGLPSILVPSPYVTADHQTKNASALVENGAALLVKEEALTGVTLV
EAIRQALEQRDEMANASRALGFPDASDALADLVEEVIQ

Sequences:

>Translated_358_residues
MKIMISGGGTGGHIYPALALIETLKKRHPDLQVQYIGTENGLEADLVPRAGVPFKSIQIAGLKRSLSLENVKTAYWFLKA
VRALKKDMAAFKPDVVIGTGGFVSGPVVYTAQQLGIPTILHEQNSIPGLTNKFLSKKADRVALSFKGSDVHFPGANVRLI
GNPRGSEVLQTEVDEASVREQYRLDDRPIVLVYGGSRGAEAINRAVVEAIPSLSELPINVLYVTGKVHFDAVSKQAPSSD
NVHIHPYVYDMPSLLACTSLVISRAGASTISELTALGLPSILVPSPYVTADHQTKNASALVENGAALLVKEEALTGVTLV
EAIRQALEQRDEMANASRALGFPDASDALADLVEEVIQ
>Mature_358_residues
MKIMISGGGTGGHIYPALALIETLKKRHPDLQVQYIGTENGLEADLVPRAGVPFKSIQIAGLKRSLSLENVKTAYWFLKA
VRALKKDMAAFKPDVVIGTGGFVSGPVVYTAQQLGIPTILHEQNSIPGLTNKFLSKKADRVALSFKGSDVHFPGANVRLI
GNPRGSEVLQTEVDEASVREQYRLDDRPIVLVYGGSRGAEAINRAVVEAIPSLSELPINVLYVTGKVHFDAVSKQAPSSD
NVHIHPYVYDMPSLLACTSLVISRAGASTISELTALGLPSILVPSPYVTADHQTKNASALVENGAALLVKEEALTGVTLV
EAIRQALEQRDEMANASRALGFPDASDALADLVEEVIQ

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=365, Percent_Identity=35.6164383561644, Blast_Score=188, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_EXISA (C4L5U5)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887196.1
- ProteinModelPortal:   C4L5U5
- GeneID:   7870724
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2837
- OMA:   IGFGGYP
- ProtClustDB:   CLSK2489572
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38280; Mature: 38280

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMISGGGTGGHIYPALALIETLKKRHPDLQVQYIGTENGLEADLVPRAGVPFKSIQIA
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEE
GLKRSLSLENVKTAYWFLKAVRALKKDMAAFKPDVVIGTGGFVSGPVVYTAQQLGIPTIL
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEHHHHCCCEEE
HEQNSIPGLTNKFLSKKADRVALSFKGSDVHFPGANVRLIGNPRGSEVLQTEVDEASVRE
ECCCCCCCHHHHHHHCCCCEEEEEECCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHH
QYRLDDRPIVLVYGGSRGAEAINRAVVEAIPSLSELPINVLYVTGKVHFDAVSKQAPSSD
HHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHCCEEEEEEEEEEEEEHHHCCCCCCC
NVHIHPYVYDMPSLLACTSLVISRAGASTISELTALGLPSILVPSPYVTADHQTKNASAL
CEEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCEECCCCCCCHHHH
VENGAALLVKEEALTGVTLVEAIRQALEQRDEMANASRALGFPDASDALADLVEEVIQ
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MKIMISGGGTGGHIYPALALIETLKKRHPDLQVQYIGTENGLEADLVPRAGVPFKSIQIA
CEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEE
GLKRSLSLENVKTAYWFLKAVRALKKDMAAFKPDVVIGTGGFVSGPVVYTAQQLGIPTIL
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEHHHHCCCEEE
HEQNSIPGLTNKFLSKKADRVALSFKGSDVHFPGANVRLIGNPRGSEVLQTEVDEASVRE
ECCCCCCCHHHHHHHCCCCEEEEEECCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHH
QYRLDDRPIVLVYGGSRGAEAINRAVVEAIPSLSELPINVLYVTGKVHFDAVSKQAPSSD
HHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHCCEEEEEEEEEEEEEHHHCCCCCCC
NVHIHPYVYDMPSLLACTSLVISRAGASTISELTALGLPSILVPSPYVTADHQTKNASAL
CEEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCEECCCCCCCHHHH
VENGAALLVKEEALTGVTLVEAIRQALEQRDEMANASRALGFPDASDALADLVEEVIQ
HHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA