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The map label for this gene is coaD

Identifier: 229918536

GI number: 229918536

Start: 2786862

End: 2787356

Strand: Direct

Name: coaD

Synonym: EAT1b_2823

Alternate gene names: 229918536

Gene position: 2786862-2787356 (Clockwise)

Preceding gene: 229918535

Following gene: 229918537

Centisome position: 92.9

GC content: 49.29

Gene sequence:

>495_bases
ATGAAACGGATTGCGATTTGTCCGGGTAGCTTTGACCCCATCACGAACGGACATCTAGATATTATTGAACGAGCGGCGGC
CATTTTTGACGAGGTCATAGTCGCCGTCCTTGAAAATTCAAGCAAGGCCCCATTGTTTGATGTGGAAGAACGACTGGGAC
TGATTCGAGACGTGACGACACATCTGCCAAACGTGTCGGCCGACGCGTTCGGTGGATTGCTTGTCGAGTATGCCGCAGAG
CGGGAAGCGGCGACGATCGTCCGTGGGCTCCGTGCAGTCTCAGATTTCGAATACGAGCTTCAAATCGCATCAATTAACAA
AAAGTTGAATGAGAACGTCGAGACGTTGTTCATGATGACGAATAGTCAATATTCGTTCCTCAGCTCGTCGATTGTCAAAG
AAGTGGCGAAATATGGGGCGTCGGTCAGTGAGCTCGTACCGGAACAGGTTGAAATTGCCTTACGTAAAAAGTATCAAGTG
AGTTCGGGACAATGA

Upstream 100 bases:

>100_bases
TTACCGGAACGAGTAGGACGATTTGAACGAATTAAAGAACAGCGATACTCAGATGTCATCACCATCAGTTTCTATGAGTA
CGCATCGGAGGAGTGACACG

Downstream 100 bases:

>100_bases
AATCGTTAAAGATCGGTCTCGGTTTACTCGTCACAGTTCTTCTCTTCCTGTTCGTCCCACTTCCTTACTACATCTCTTCA
CCCGGAGCGGCGACCTCAAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKRIAICPGSFDPITNGHLDIIERAAAIFDEVIVAVLENSSKAPLFDVEERLGLIRDVTTHLPNVSADAFGGLLVEYAAE
REAATIVRGLRAVSDFEYELQIASINKKLNENVETLFMMTNSQYSFLSSSIVKEVAKYGASVSELVPEQVEIALRKKYQV
SSGQ

Sequences:

>Translated_164_residues
MKRIAICPGSFDPITNGHLDIIERAAAIFDEVIVAVLENSSKAPLFDVEERLGLIRDVTTHLPNVSADAFGGLLVEYAAE
REAATIVRGLRAVSDFEYELQIASINKKLNENVETLFMMTNSQYSFLSSSIVKEVAKYGASVSELVPEQVEIALRKKYQV
SSGQ
>Mature_164_residues
MKRIAICPGSFDPITNGHLDIIERAAAIFDEVIVAVLENSSKAPLFDVEERLGLIRDVTTHLPNVSADAFGGLLVEYAAE
REAATIVRGLRAVSDFEYELQIASINKKLNENVETLFMMTNSQYSFLSSSIVKEVAKYGASVSELVPEQVEIALRKKYQV
SSGQ

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=47.1337579617834, Blast_Score=167, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_EXISA (C4L5T1)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002887182.1
- ProteinModelPortal:   C4L5T1
- GeneID:   7870710
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2823
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18039; Mature: 18039

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIAICPGSFDPITNGHLDIIERAAAIFDEVIVAVLENSSKAPLFDVEERLGLIRDVTT
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
HLPNVSADAFGGLLVEYAAEREAATIVRGLRAVSDFEYELQIASINKKLNENVETLFMMT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHCCCEEEEEEE
NSQYSFLSSSIVKEVAKYGASVSELVPEQVEIALRKKYQVSSGQ
CCCHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKRIAICPGSFDPITNGHLDIIERAAAIFDEVIVAVLENSSKAPLFDVEERLGLIRDVTT
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
HLPNVSADAFGGLLVEYAAEREAATIVRGLRAVSDFEYELQIASINKKLNENVETLFMMT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHCCCEEEEEEE
NSQYSFLSSSIVKEVAKYGASVSELVPEQVEIALRKKYQVSSGQ
CCCHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA