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The map label for this gene is typA [H]

Identifier: 229918509

GI number: 229918509

Start: 2762269

End: 2764113

Strand: Direct

Name: typA [H]

Synonym: EAT1b_2796

Alternate gene names: 229918509

Gene position: 2762269-2764113 (Clockwise)

Preceding gene: 229918507

Following gene: 229918510

Centisome position: 92.08

GC content: 48.89

Gene sequence:

>1845_bases
ATGAACGTAAGAACAAACCTTCGTAACGTAGCCATCATCGCGCACGTTGACCACGGTAAAACAACGTTAGTCGATGAATT
ATTGAAACAGTCTGGTACTTTCCGGACGAACGAGGCAGTCGCAGAACGCGCGATGGACTCGAACGATATCGAGCGTGAGC
GCGGAATCACGATTCTCGCAAAAAACACAGCAATCGATTATAAAGAGACGCGCATCAACATCGTAGATACACCAGGTCAC
GCAGACTTCGGTGGAGAAGTTGAGCGAATCATGCGTATGGTAGACGGCGTTATCCTTGTTGTCGATGCGCGTGAAGGCTG
TATGCCACAAACACGTTTCGTATTGAAAAAAGCTCTCGACCAAGGACTTCGTCCGATTGTCGTCGTCAACAAAATCGATA
AGCCGATGGTTCGTCCACTCGACGTTGTCGATGAAGTTGTTGATCTCTTGATCGACCTTGGCGCAGATGAAGATCAACTT
GAATTCCCTGTCGTCTACACATCAGCAGTCAGCGGTTCAAGTTCGTTCGATCCTGACCCAGAAAAACAAGAAGATACAAT
CACGCACGTGCTCGACACGATTCTTGAAAACACGCCGGCTCCAGTGGACAACTCAGACGAGCCACTTCAATTCCAAGTGA
CGATGCTCGACTATGATAACTACCTCGGTCGTATCGGTGTAGGTCGCGTCTTCCGTGGGAAAATCAAAGTCGGTGAGCAA
GTATCGCTTTGTAAGACAGACGGTACGGTGAAGCAACTTCGTGTCACGAAATTGTTCGGTTACTTCGGCCTCAAGCGCGT
CGAAATCGAAGAAGCAAAAGCAGGGGACTTGATCGCTATCGCCGGAATGGAAGATATCAACGTCGGTGAAACGGTAACGC
CAGTCGGTAAAGAAGAGCCACTTCCGCTCCTTCGCATCGATGAGCCAACGCTTCAAATGCGTTTCATGACAAACAACTCT
CCGTTCGCAGGACGTGAAGGCGATTTCGTGACAGCACGTAAAATCGAAGAACGTTTGATGAAACAACTCGAGACGGACGT
TTCACTCCGTGTCGAAAATACAGATTCACCAGACCAATGGATCGTATCAGGACGCGGTGAGCTTCACCTCGGGATCTTGA
TCGAGAACATGCGTCGTGAAGGTTACGAGCTCCAAGTGTCGAAACCACAAGTTATCATCCGTGAAGACGAGAGCGGCACG
AAAGTTGAGCCGTTCGAGCGCGTCATCATCGACGTACCTGAAGAGTATACAGGTTCAGTCATGGAATCGATTGGTCTCCG
TAAAGGTGAGCTTGCGAACATGAACACGAATGACAACGGTCAGACGCGTATGGAATTCCTCGTGCCATCACGTGGTCTCA
TCGGTTACCGTAACGAATTCTTGTCAGCGACACGTGGATACGGAATCTTGAACCATACGTTCGAAGAGTATCGTCCGTAT
ATCGCTGCTGATATCGGTGGCCGTCGTAGCGGTGTTATGGTATGTATCGAAAACGGGAAGTCGACGGCTTACTCAATCGG
TGCCCTCGAAGACCGTGGAACAATCTTTATTGAGCCAGGTACGGATGTGTATGAAGGAATGATCATTGGGGAATGTAACC
GTGACGTTGACCTTGCCATTAACGCCGTTAAAGGGAAGCAATTGACGAACATGCGTGCTTCTGCAAAAGACTCGACACAA
GTCTTGAAACGTCCGCGCGTCTTCTCGCTTGAAGAGTCGCTCACGTTCTTGAACGATGACGAGTACTGTGAAATCACGCC
GGAGTCAATCCGTCTTCGTAAGAAAATCTTGAACAAGAACGAACGTGAGAAAGCTGACAAGCGTCGTAAACTTGGTAAAG
AATAA

Upstream 100 bases:

>100_bases
GTTCACAGTCGATTCCACTCGACAAAGGTACTGTGACGTGTGCTATACTCTTAAAGTTGAAGAAAAGTTGAAATTTTTTA
AATAAGAGAGGAATAACTAC

Downstream 100 bases:

>100_bases
GTTAGCAGAAAGGGGACGCTTCGGCGTTCCCTTTTGCATGGAATAGTGTAGAATGGATGTGTATGAAATAAAGGGGGACT
CTTTGTCTTGAAAGCTTCTC

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MNVRTNLRNVAIIAHVDHGKTTLVDELLKQSGTFRTNEAVAERAMDSNDIERERGITILAKNTAIDYKETRINIVDTPGH
ADFGGEVERIMRMVDGVILVVDAREGCMPQTRFVLKKALDQGLRPIVVVNKIDKPMVRPLDVVDEVVDLLIDLGADEDQL
EFPVVYTSAVSGSSSFDPDPEKQEDTITHVLDTILENTPAPVDNSDEPLQFQVTMLDYDNYLGRIGVGRVFRGKIKVGEQ
VSLCKTDGTVKQLRVTKLFGYFGLKRVEIEEAKAGDLIAIAGMEDINVGETVTPVGKEEPLPLLRIDEPTLQMRFMTNNS
PFAGREGDFVTARKIEERLMKQLETDVSLRVENTDSPDQWIVSGRGELHLGILIENMRREGYELQVSKPQVIIREDESGT
KVEPFERVIIDVPEEYTGSVMESIGLRKGELANMNTNDNGQTRMEFLVPSRGLIGYRNEFLSATRGYGILNHTFEEYRPY
IAADIGGRRSGVMVCIENGKSTAYSIGALEDRGTIFIEPGTDVYEGMIIGECNRDVDLAINAVKGKQLTNMRASAKDSTQ
VLKRPRVFSLEESLTFLNDDEYCEITPESIRLRKKILNKNEREKADKRRKLGKE

Sequences:

>Translated_614_residues
MNVRTNLRNVAIIAHVDHGKTTLVDELLKQSGTFRTNEAVAERAMDSNDIERERGITILAKNTAIDYKETRINIVDTPGH
ADFGGEVERIMRMVDGVILVVDAREGCMPQTRFVLKKALDQGLRPIVVVNKIDKPMVRPLDVVDEVVDLLIDLGADEDQL
EFPVVYTSAVSGSSSFDPDPEKQEDTITHVLDTILENTPAPVDNSDEPLQFQVTMLDYDNYLGRIGVGRVFRGKIKVGEQ
VSLCKTDGTVKQLRVTKLFGYFGLKRVEIEEAKAGDLIAIAGMEDINVGETVTPVGKEEPLPLLRIDEPTLQMRFMTNNS
PFAGREGDFVTARKIEERLMKQLETDVSLRVENTDSPDQWIVSGRGELHLGILIENMRREGYELQVSKPQVIIREDESGT
KVEPFERVIIDVPEEYTGSVMESIGLRKGELANMNTNDNGQTRMEFLVPSRGLIGYRNEFLSATRGYGILNHTFEEYRPY
IAADIGGRRSGVMVCIENGKSTAYSIGALEDRGTIFIEPGTDVYEGMIIGECNRDVDLAINAVKGKQLTNMRASAKDSTQ
VLKRPRVFSLEESLTFLNDDEYCEITPESIRLRKKILNKNEREKADKRRKLGKE
>Mature_614_residues
MNVRTNLRNVAIIAHVDHGKTTLVDELLKQSGTFRTNEAVAERAMDSNDIERERGITILAKNTAIDYKETRINIVDTPGH
ADFGGEVERIMRMVDGVILVVDAREGCMPQTRFVLKKALDQGLRPIVVVNKIDKPMVRPLDVVDEVVDLLIDLGADEDQL
EFPVVYTSAVSGSSSFDPDPEKQEDTITHVLDTILENTPAPVDNSDEPLQFQVTMLDYDNYLGRIGVGRVFRGKIKVGEQ
VSLCKTDGTVKQLRVTKLFGYFGLKRVEIEEAKAGDLIAIAGMEDINVGETVTPVGKEEPLPLLRIDEPTLQMRFMTNNS
PFAGREGDFVTARKIEERLMKQLETDVSLRVENTDSPDQWIVSGRGELHLGILIENMRREGYELQVSKPQVIIREDESGT
KVEPFERVIIDVPEEYTGSVMESIGLRKGELANMNTNDNGQTRMEFLVPSRGLIGYRNEFLSATRGYGILNHTFEEYRPY
IAADIGGRRSGVMVCIENGKSTAYSIGALEDRGTIFIEPGTDVYEGMIIGECNRDVDLAINAVKGKQLTNMRASAKDSTQ
VLKRPRVFSLEESLTFLNDDEYCEITPESIRLRKKILNKNEREKADKRRKLGKE

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=513, Percent_Identity=27.4853801169591, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI94966754, Length=137, Percent_Identity=45.2554744525547, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI4503483, Length=150, Percent_Identity=36, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI25306283, Length=130, Percent_Identity=41.5384615384615, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI25306287, Length=130, Percent_Identity=41.5384615384615, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19923640, Length=130, Percent_Identity=41.5384615384615, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310132016, Length=112, Percent_Identity=43.75, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI310110807, Length=112, Percent_Identity=43.75, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI310123363, Length=112, Percent_Identity=43.75, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=37.2413793103448, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI34147630, Length=278, Percent_Identity=32.3741007194245, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI217272894, Length=189, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI217272892, Length=189, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI94966752, Length=133, Percent_Identity=33.0827067669173, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI53729339, Length=163, Percent_Identity=32.5153374233129, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI53729337, Length=163, Percent_Identity=32.5153374233129, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI48994988, Length=604, Percent_Identity=52.317880794702, Blast_Score=649, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=508, Percent_Identity=28.9370078740157, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789738, Length=167, Percent_Identity=38.9221556886228, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=30.3448275862069, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790412, Length=277, Percent_Identity=30.3249097472924, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789737, Length=277, Percent_Identity=30.3249097472924, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789559, Length=166, Percent_Identity=33.7349397590361, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17556745, Length=455, Percent_Identity=28.1318681318681, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17557151, Length=291, Percent_Identity=30.2405498281787, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17533571, Length=143, Percent_Identity=39.8601398601399, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17506493, Length=167, Percent_Identity=34.1317365269461, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988819, Length=129, Percent_Identity=37.2093023255814, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988811, Length=129, Percent_Identity=37.2093023255814, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=140, Percent_Identity=36.4285714285714, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17556456, Length=307, Percent_Identity=27.3615635179153, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25141371, Length=276, Percent_Identity=27.8985507246377, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994658, Length=151, Percent_Identity=34.4370860927152, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=526, Percent_Identity=28.7072243346008, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324707, Length=155, Percent_Identity=41.9354838709677, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320593, Length=155, Percent_Identity=41.9354838709677, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324761, Length=273, Percent_Identity=32.967032967033, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6323098, Length=175, Percent_Identity=34.2857142857143, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=147, Percent_Identity=36.734693877551, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6322359, Length=133, Percent_Identity=34.5864661654135, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324550, Length=125, Percent_Identity=32.8, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706572, Length=515, Percent_Identity=25.8252427184466, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28574573, Length=165, Percent_Identity=38.1818181818182, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281363316, Length=270, Percent_Identity=33.7037037037037, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17864358, Length=270, Percent_Identity=33.7037037037037, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24585711, Length=159, Percent_Identity=37.1069182389937, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24585713, Length=159, Percent_Identity=37.1069182389937, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24585709, Length=159, Percent_Identity=37.1069182389937, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21357743, Length=193, Percent_Identity=35.7512953367876, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24582462, Length=145, Percent_Identity=38.6206896551724, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19921738, Length=235, Percent_Identity=32.7659574468085, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221458488, Length=162, Percent_Identity=37.6543209876543, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28572034, Length=128, Percent_Identity=39.0625, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 68835; Mature: 68835

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRTNLRNVAIIAHVDHGKTTLVDELLKQSGTFRTNEAVAERAMDSNDIERERGITILA
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHCCEEEEE
KNTAIDYKETRINIVDTPGHADFGGEVERIMRMVDGVILVVDAREGCMPQTRFVLKKALD
ECCEECEEEEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHH
QGLRPIVVVNKIDKPMVRPLDVVDEVVDLLIDLGADEDQLEFPVVYTSAVSGSSSFDPDP
HCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCC
EKQEDTITHVLDTILENTPAPVDNSDEPLQFQVTMLDYDNYLGRIGVGRVFRGKIKVGEQ
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHCCCCCCCEEECEECCCCE
VSLCKTDGTVKQLRVTKLFGYFGLKRVEIEEAKAGDLIAIAGMEDINVGETVTPVGKEEP
EEEEECCCCHHHHHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCCCCEECCCCCCCC
LPLLRIDEPTLQMRFMTNNSPFAGREGDFVTARKIEERLMKQLETDVSLRVENTDSPDQW
CCEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
IVSGRGELHLGILIENMRREGYELQVSKPQVIIREDESGTKVEPFERVIIDVPEEYTGSV
EEECCCCEEEEEEEEHHHCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHH
MESIGLRKGELANMNTNDNGQTRMEFLVPSRGLIGYRNEFLSATRGYGILNHTFEEYRPY
HHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHCCHHHCCCE
IAADIGGRRSGVMVCIENGKSTAYSIGALEDRGTIFIEPGTDVYEGMIIGECNRDVDLAI
EEEECCCCCCCEEEEEECCCCCEEEEECCCCCCEEEECCCCHHHCCEEEECCCCCCEEEE
NAVKGKQLTNMRASAKDSTQVLKRPRVFSLEESLTFLNDDEYCEITPESIRLRKKILNKN
EEECCCHHHCCCCCCCHHHHHHHCCCEEEHHHHHHCCCCCCEEEECHHHHHHHHHHHCCC
EREKADKRRKLGKE
HHHHHHHHHHCCCC
>Mature Secondary Structure
MNVRTNLRNVAIIAHVDHGKTTLVDELLKQSGTFRTNEAVAERAMDSNDIERERGITILA
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHCCEEEEE
KNTAIDYKETRINIVDTPGHADFGGEVERIMRMVDGVILVVDAREGCMPQTRFVLKKALD
ECCEECEEEEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHH
QGLRPIVVVNKIDKPMVRPLDVVDEVVDLLIDLGADEDQLEFPVVYTSAVSGSSSFDPDP
HCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCC
EKQEDTITHVLDTILENTPAPVDNSDEPLQFQVTMLDYDNYLGRIGVGRVFRGKIKVGEQ
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHCCCCCCCEEECEECCCCE
VSLCKTDGTVKQLRVTKLFGYFGLKRVEIEEAKAGDLIAIAGMEDINVGETVTPVGKEEP
EEEEECCCCHHHHHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCCCCEECCCCCCCC
LPLLRIDEPTLQMRFMTNNSPFAGREGDFVTARKIEERLMKQLETDVSLRVENTDSPDQW
CCEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
IVSGRGELHLGILIENMRREGYELQVSKPQVIIREDESGTKVEPFERVIIDVPEEYTGSV
EEECCCCEEEEEEEEHHHCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHH
MESIGLRKGELANMNTNDNGQTRMEFLVPSRGLIGYRNEFLSATRGYGILNHTFEEYRPY
HHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCHHCCHHHCCCE
IAADIGGRRSGVMVCIENGKSTAYSIGALEDRGTIFIEPGTDVYEGMIIGECNRDVDLAI
EEEECCCCCCCEEEEEECCCCCEEEEECCCCCCEEEECCCCHHHCCEEEECCCCCCEEEE
NAVKGKQLTNMRASAKDSTQVLKRPRVFSLEESLTFLNDDEYCEITPESIRLRKKILNKN
EEECCCHHHCCCCCCCHHHHHHHCCCEEEHHHHHHCCCCCCEEEECHHHHHHHHHHHCCC
EREKADKRRKLGKE
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]