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The map label for this gene is suhB [H]

Identifier: 229918507

GI number: 229918507

Start: 2760627

End: 2761880

Strand: Direct

Name: suhB [H]

Synonym: EAT1b_2794

Alternate gene names: 229918507

Gene position: 2760627-2761880 (Clockwise)

Preceding gene: 229918506

Following gene: 229918509

Centisome position: 92.02

GC content: 49.6

Gene sequence:

>1254_bases
ATGATAGAATGGTTTGCAGTCGACTTAATCAAACAAGCGGGAGAACTGATTCGTCGCGAGATTGATCAAAGTTATGAAGT
GGAACGAAAGACGGGGAAAGGGGACTTGGTCACTGAAATCGACCGCGCGGTGGAACAACTGATTGTCCGTCGAATCCAAC
ATACATTTCCGGAACATCAGATTATGGGGGAAGAGGGGACGACAGATCAGCCAGAACAATTGACCGGTACCGTCTGGTTT
GTCGACCCGATTGATGGGACGTTAAATTTTATTCATCAAAAACGTATGTTTGCCATCTCCATCGCGATCATGATAGATGG
GGTCGTGGAATATGGATTCGTCTATGACGTCATGGCGGATGAGATGTTCATGGCGCGGAAAGGATACGGGGCGACATTGA
ACGGTCGGACGTTGACGACCCTTCATGAACATCATGTCCGAGACGCGTTTTTAAGTATGAATGCGACGTGGGTCACGCCG
AACCACCAGATTGCCCCGGAAATACTCGCTCCGATTGTTCGGGACTCGATTGGTACGCGAGCTCATGGTGCTGCATCGCT
TGAATTAGCCTGGCTTGCTGCGGGTCGCGTGGACGGCTACATCACCATGCGCAATATGCCATGGGATTATGCTGCTGGAA
AGTTACTCGTTGAAGAGGTAGGCGGGCGTGTCGTTTCCTTATATGGTGAGCCGATTCGGTATGACGGAAAAACATCTGTC
CTGGCTGGGAGCGATTCATTTGTAAATGACGTCATCAAACATTACGTCATCACAAAAGGGGTCACAGCTGAAGCGAAGCC
GGACTTACACATCGTGGAACATGATTCGTATGAAGAAATCCGCGACTTACTCGTCTTGGCGAATCCGAATGAAGCGATGG
TCCGGGAACAATTCGAGGAAGGTCGTACGTACAAAGCGTTACTCGGTGGTGAGATTGTCGGTGCGTATATGCTCGTCTCA
CACGAAGGCAATCGGGTTGAACTCGTCAATATCGCAGTGAAACCCGAACGTCAAAACCAAACGATTGGTCAACGCATGTT
ACAAGACGCAGTGAAGCGGGCCACGATGATTGGTGGGAAAGAACTACTCGTCTGTACAGGGAATTCAAGCATCATGCAGT
TGCGTTTTTACCAACAAGCCGGATTCCGATTCGATTCGGTGGAACGCGATTATTTTCGTGATCACGGGTACGATGACATC
GAAGAAGATGGGCTCGTTTTACGCGACCGCATCTGCTTGACTCGTCCGCTATAA

Upstream 100 bases:

>100_bases
ATTATTGCGTCTCGAAGCCTAACCATTACACACACATTCAACCAGTATTCCGAGCGGATACTGGTTTTTGTTTGGTACAA
TACAGTTGAGGTGATCACAG

Downstream 100 bases:

>100_bases
AGGCAAGTTAAAAGGGTTACTCCGACATGATCCCGGAGTAACCCTTTTTTATGATTGACGTTCTGAAAGAATGCGGCGAC
GCAATTGAATACCAAAGAAT

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MIEWFAVDLIKQAGELIRREIDQSYEVERKTGKGDLVTEIDRAVEQLIVRRIQHTFPEHQIMGEEGTTDQPEQLTGTVWF
VDPIDGTLNFIHQKRMFAISIAIMIDGVVEYGFVYDVMADEMFMARKGYGATLNGRTLTTLHEHHVRDAFLSMNATWVTP
NHQIAPEILAPIVRDSIGTRAHGAASLELAWLAAGRVDGYITMRNMPWDYAAGKLLVEEVGGRVVSLYGEPIRYDGKTSV
LAGSDSFVNDVIKHYVITKGVTAEAKPDLHIVEHDSYEEIRDLLVLANPNEAMVREQFEEGRTYKALLGGEIVGAYMLVS
HEGNRVELVNIAVKPERQNQTIGQRMLQDAVKRATMIGGKELLVCTGNSSIMQLRFYQQAGFRFDSVERDYFRDHGYDDI
EEDGLVLRDRICLTRPL

Sequences:

>Translated_417_residues
MIEWFAVDLIKQAGELIRREIDQSYEVERKTGKGDLVTEIDRAVEQLIVRRIQHTFPEHQIMGEEGTTDQPEQLTGTVWF
VDPIDGTLNFIHQKRMFAISIAIMIDGVVEYGFVYDVMADEMFMARKGYGATLNGRTLTTLHEHHVRDAFLSMNATWVTP
NHQIAPEILAPIVRDSIGTRAHGAASLELAWLAAGRVDGYITMRNMPWDYAAGKLLVEEVGGRVVSLYGEPIRYDGKTSV
LAGSDSFVNDVIKHYVITKGVTAEAKPDLHIVEHDSYEEIRDLLVLANPNEAMVREQFEEGRTYKALLGGEIVGAYMLVS
HEGNRVELVNIAVKPERQNQTIGQRMLQDAVKRATMIGGKELLVCTGNSSIMQLRFYQQAGFRFDSVERDYFRDHGYDDI
EEDGLVLRDRICLTRPL
>Mature_417_residues
MIEWFAVDLIKQAGELIRREIDQSYEVERKTGKGDLVTEIDRAVEQLIVRRIQHTFPEHQIMGEEGTTDQPEQLTGTVWF
VDPIDGTLNFIHQKRMFAISIAIMIDGVVEYGFVYDVMADEMFMARKGYGATLNGRTLTTLHEHHVRDAFLSMNATWVTP
NHQIAPEILAPIVRDSIGTRAHGAASLELAWLAAGRVDGYITMRNMPWDYAAGKLLVEEVGGRVVSLYGEPIRYDGKTSV
LAGSDSFVNDVIKHYVITKGVTAEAKPDLHIVEHDSYEEIRDLLVLANPNEAMVREQFEEGRTYKALLGGEIVGAYMLVS
HEGNRVELVNIAVKPERQNQTIGQRMLQDAVKRATMIGGKELLVCTGNSSIMQLRFYQQAGFRFDSVERDYFRDHGYDDI
EEDGLVLRDRICLTRPL

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=29.6442687747036, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI221625487, Length=243, Percent_Identity=30.4526748971193, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=31.2236286919831, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI221625507, Length=142, Percent_Identity=37.3239436619718, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1788882, Length=230, Percent_Identity=37.3913043478261, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193202572, Length=264, Percent_Identity=28.7878787878788, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193202570, Length=261, Percent_Identity=28.735632183908, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6321836, Length=240, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320493, Length=229, Percent_Identity=26.6375545851528, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324508, Length=173, Percent_Identity=27.7456647398844, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21357329, Length=235, Percent_Identity=32.3404255319149, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24664926, Length=256, Percent_Identity=29.6875, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24664922, Length=253, Percent_Identity=30.4347826086957, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21357303, Length=250, Percent_Identity=28.8, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357957, Length=255, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24664918, Length=224, Percent_Identity=29.9107142857143, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 47119; Mature: 47119

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEWFAVDLIKQAGELIRREIDQSYEVERKTGKGDLVTEIDRAVEQLIVRRIQHTFPEHQ
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
IMGEEGTTDQPEQLTGTVWFVDPIDGTLNFIHQKRMFAISIAIMIDGVVEYGFVYDVMAD
ECCCCCCCCCCHHHEEEEEEEECCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHH
EMFMARKGYGATLNGRTLTTLHEHHVRDAFLSMNATWVTPNHQIAPEILAPIVRDSIGTR
HHHHHHCCCCCEECCCEEEHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCC
AHGAASLELAWLAAGRVDGYITMRNMPWDYAAGKLLVEEVGGRVVSLYGEPIRYDGKTSV
CCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCEEECCCEEE
LAGSDSFVNDVIKHYVITKGVTAEAKPDLHIVEHDSYEEIRDLLVLANPNEAMVREQFEE
EECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHCEEEEECCCHHHHHHHHHC
GRTYKALLGGEIVGAYMLVSHEGNRVELVNIAVKPERQNQTIGQRMLQDAVKRATMIGGK
CCEEEEHHCCHHEEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
ELLVCTGNSSIMQLRFYQQAGFRFDSVERDYFRDHGYDDIEEDGLVLRDRICLTRPL
EEEEEECCCCEEEEEEEHHHCCCCCCCCHHHHHCCCCCCCCCCCEEEECCCHHCCCC
>Mature Secondary Structure
MIEWFAVDLIKQAGELIRREIDQSYEVERKTGKGDLVTEIDRAVEQLIVRRIQHTFPEHQ
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
IMGEEGTTDQPEQLTGTVWFVDPIDGTLNFIHQKRMFAISIAIMIDGVVEYGFVYDVMAD
ECCCCCCCCCCHHHEEEEEEEECCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHH
EMFMARKGYGATLNGRTLTTLHEHHVRDAFLSMNATWVTPNHQIAPEILAPIVRDSIGTR
HHHHHHCCCCCEECCCEEEHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCC
AHGAASLELAWLAAGRVDGYITMRNMPWDYAAGKLLVEEVGGRVVSLYGEPIRYDGKTSV
CCCCCEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCEEECCCEEE
LAGSDSFVNDVIKHYVITKGVTAEAKPDLHIVEHDSYEEIRDLLVLANPNEAMVREQFEE
EECCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHCEEEEECCCHHHHHHHHHC
GRTYKALLGGEIVGAYMLVSHEGNRVELVNIAVKPERQNQTIGQRMLQDAVKRATMIGGK
CCEEEEHHCCHHEEEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
ELLVCTGNSSIMQLRFYQQAGFRFDSVERDYFRDHGYDDIEEDGLVLRDRICLTRPL
EEEEEECCCCEEEEEEEHHHCCCCCCCCHHHHHCCCCCCCCCCCEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]