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The map label for this gene is mreB [H]

Identifier: 229918387

GI number: 229918387

Start: 2641523

End: 2642560

Strand: Direct

Name: mreB [H]

Synonym: EAT1b_2672

Alternate gene names: 229918387

Gene position: 2641523-2642560 (Clockwise)

Preceding gene: 229918386

Following gene: 229918388

Centisome position: 88.05

GC content: 52.5

Gene sequence:

>1038_bases
ATGTTTCGTAGTTTTAACCGAGAAATCGGAATCGACCTTGGAACAGCTAACACGCTCGTTTATGTAAAGGGTCAAGGAAT
TGTTGTTCGTGAACCGTCCGTCGTGGCGTTCCGCACAGATACAGGTAGAATTGAGGCCGTTGGGAACCAGGCCAAAGATA
TGATTGGACGTACTCCGGGGAACGTCTCTGCACGTCGTCCGATGAAAGACGGTGTCATCGCTGACTTCGAAACGACAGCG
ACGATGATCAAATACTTCATGGAGCAAGCTCAAAAATCAAAAGGCGGTTTGTTCTCATCGAAGACGAACGTCATGATTTG
TGTCCCAAGCGGCATCACGTCTGTTGAAAAACGTGCCGTGGAAGACGCTGCGAAACAAGCAGGCGCTCGTGAAGCATACA
CAATCGAGGAACCGTTCGCGGCAGCAATCGGTGCAGGTCTCCCGGTTTGGGAACCGACTGGCTCGATGGTCGTCGATATC
GGTGGCGGTACGACCGAAGTCGCAGTGATCTCACTCGGCGGCATCGTGACAAGCCAATCGATTCGTGTCGGTGGTGACGA
AATGGATGATGCCATTATTCGTTACATCAAGAACAAGTACAACCTCATGATCGGGGAACGTACAGCCGAGACGCTCAAAA
TGGAAGTCGGTTCGGCGCGCATCGACGCATCGAACGAAGATGAGAAGATGGAAATCCGTGGTCGCGACCTCGTGACAGGA
CTTCCGAAGCAAATCGAAGTCACGTCTGCAGAAGTGTGTGAAGCTCTTTCTGATACAGTCGAAGCGATTTTAGCAGGGGT
CAAGCAAACGCTTGAGCAAACACCTCCAGAACTTGCGGCTGACGTCATGGACCGCGGGATCGTCTTGACTGGCGGCGGCG
CGCTCCTCAAAAACTTGGACGACGTGATCTCAGACGAGACACACATCCCGACACTCGTTGCGGATGAGCCACTCGACTGC
GTAGCGGTCGGTACTGGAAAATCTCTTGAAATGATGGACGTCCTCCGTTCGAAATCAGGCATCTCGTCACGTCGATGA

Upstream 100 bases:

>100_bases
GATGCGGTTATTGTAAATAACCTGTAATCGAATGAACGTTTTCAAACATGATTTTTCCGTTATAATAAAAAATAGTGTAA
TGAAGAGAGGAGCAACACCT

Downstream 100 bases:

>100_bases
GAGGTGAGACACGATGAGCCGATTCGTACGTAATAAAAAGCTCATCATCACGCTAATTGTACTGATCTTGTTTTTCGTCA
TTTTAGGGGTTTCGATTCGA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MFRSFNREIGIDLGTANTLVYVKGQGIVVREPSVVAFRTDTGRIEAVGNQAKDMIGRTPGNVSARRPMKDGVIADFETTA
TMIKYFMEQAQKSKGGLFSSKTNVMICVPSGITSVEKRAVEDAAKQAGAREAYTIEEPFAAAIGAGLPVWEPTGSMVVDI
GGGTTEVAVISLGGIVTSQSIRVGGDEMDDAIIRYIKNKYNLMIGERTAETLKMEVGSARIDASNEDEKMEIRGRDLVTG
LPKQIEVTSAEVCEALSDTVEAILAGVKQTLEQTPPELAADVMDRGIVLTGGGALLKNLDDVISDETHIPTLVADEPLDC
VAVGTGKSLEMMDVLRSKSGISSRR

Sequences:

>Translated_345_residues
MFRSFNREIGIDLGTANTLVYVKGQGIVVREPSVVAFRTDTGRIEAVGNQAKDMIGRTPGNVSARRPMKDGVIADFETTA
TMIKYFMEQAQKSKGGLFSSKTNVMICVPSGITSVEKRAVEDAAKQAGAREAYTIEEPFAAAIGAGLPVWEPTGSMVVDI
GGGTTEVAVISLGGIVTSQSIRVGGDEMDDAIIRYIKNKYNLMIGERTAETLKMEVGSARIDASNEDEKMEIRGRDLVTG
LPKQIEVTSAEVCEALSDTVEAILAGVKQTLEQTPPELAADVMDRGIVLTGGGALLKNLDDVISDETHIPTLVADEPLDC
VAVGTGKSLEMMDVLRSKSGISSRR
>Mature_345_residues
MFRSFNREIGIDLGTANTLVYVKGQGIVVREPSVVAFRTDTGRIEAVGNQAKDMIGRTPGNVSARRPMKDGVIADFETTA
TMIKYFMEQAQKSKGGLFSSKTNVMICVPSGITSVEKRAVEDAAKQAGAREAYTIEEPFAAAIGAGLPVWEPTGSMVVDI
GGGTTEVAVISLGGIVTSQSIRVGGDEMDDAIIRYIKNKYNLMIGERTAETLKMEVGSARIDASNEDEKMEIRGRDLVTG
LPKQIEVTSAEVCEALSDTVEAILAGVKQTLEQTPPELAADVMDRGIVLTGGGALLKNLDDVISDETHIPTLVADEPLDC
VAVGTGKSLEMMDVLRSKSGISSRR

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI167466173, Length=355, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI194248072, Length=355, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI16507237, Length=359, Percent_Identity=25.0696378830084, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI24234686, Length=352, Percent_Identity=25.2840909090909, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI5729877, Length=352, Percent_Identity=25.2840909090909, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082236, Length=338, Percent_Identity=55.6213017751479, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1788875, Length=362, Percent_Identity=24.3093922651934, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534015, Length=359, Percent_Identity=24.7910863509749, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534013, Length=359, Percent_Identity=24.7910863509749, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17534771, Length=354, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507981, Length=253, Percent_Identity=26.8774703557312, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568549, Length=354, Percent_Identity=26.271186440678, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320950, Length=357, Percent_Identity=25.7703081232493, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322426, Length=340, Percent_Identity=27.3529411764706, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319314, Length=356, Percent_Identity=25.2808988764045, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24647034, Length=358, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647038, Length=358, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24647036, Length=358, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17737967, Length=358, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28571721, Length=358, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28571719, Length=358, Percent_Identity=27.9329608938547, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24646137, Length=385, Percent_Identity=25.1948051948052, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646135, Length=385, Percent_Identity=25.1948051948052, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571678, Length=385, Percent_Identity=24.9350649350649, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36776; Mature: 36776

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSFNREIGIDLGTANTLVYVKGQGIVVREPSVVAFRTDTGRIEAVGNQAKDMIGRTPG
CCCCCCCCCCEEECCCCEEEEEECCEEEEECCCEEEEECCCCCEEECCCHHHHHHCCCCC
NVSARRPMKDGVIADFETTATMIKYFMEQAQKSKGGLFSSKTNVMICVPSGITSVEKRAV
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCHHHHHHH
EDAAKQAGAREAYTIEEPFAAAIGAGLPVWEPTGSMVVDIGGGTTEVAVISLGGIVTSQS
HHHHHHCCCCCCEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEECCE
IRVGGDEMDDAIIRYIKNKYNLMIGERTAETLKMEVGSARIDASNEDEKMEIRGRDLVTG
EEECCCHHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHC
LPKQIEVTSAEVCEALSDTVEAILAGVKQTLEQTPPELAADVMDRGIVLTGGGALLKNLD
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHH
DVISDETHIPTLVADEPLDCVAVGTGKSLEMMDVLRSKSGISSRR
HHHCCCCCCCEEECCCCCCEEEECCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFRSFNREIGIDLGTANTLVYVKGQGIVVREPSVVAFRTDTGRIEAVGNQAKDMIGRTPG
CCCCCCCCCCEEECCCCEEEEEECCEEEEECCCEEEEECCCCCEEECCCHHHHHHCCCCC
NVSARRPMKDGVIADFETTATMIKYFMEQAQKSKGGLFSSKTNVMICVPSGITSVEKRAV
CCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCHHHHHHH
EDAAKQAGAREAYTIEEPFAAAIGAGLPVWEPTGSMVVDIGGGTTEVAVISLGGIVTSQS
HHHHHHCCCCCCEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEECCE
IRVGGDEMDDAIIRYIKNKYNLMIGERTAETLKMEVGSARIDASNEDEKMEIRGRDLVTG
EEECCCHHHHHHHHHHHHHHEEEEECHHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHC
LPKQIEVTSAEVCEALSDTVEAILAGVKQTLEQTPPELAADVMDRGIVLTGGGALLKNLD
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHH
DVISDETHIPTLVADEPLDCVAVGTGKSLEMMDVLRSKSGISSRR
HHHCCCCCCCEEECCCCCCEEEECCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]