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The map label for this gene is paaG [H]

Identifier: 229918219

GI number: 229918219

Start: 2461552

End: 2462286

Strand: Direct

Name: paaG [H]

Synonym: EAT1b_2499

Alternate gene names: 229918219

Gene position: 2461552-2462286 (Clockwise)

Preceding gene: 229918212

Following gene: 229918222

Centisome position: 82.05

GC content: 53.88

Gene sequence:

>735_bases
GTGGAGATGATTCAATTGACGACACACAATGGGGTAGGGTGGTTGAAACTGAACCGACCTGAAAAGCTGAACGCCTTGAA
CGAGACGTTGCTTCGTGAAATGAAAACGGCAATCGACACATTTGAACAGGACGACGCCGTTCGCGTCATCGTCCTTGTCG
GTGAGGGACGAGCGTTCTCATCCGGACAAGATTTAACGATTGAGAGCGATGCGGACTATGGGGAATATCTAGAAGACGTG
TATCATCCGCTCGTACGTGCACTTTTCTCGAGTCGTAAACCGCTCATCGCAGGGATTCACGGTGTCGTGGCTGGAGCAGG
ACTCAGCTTGGCACTCGCGGCAGACGTTCGAATCGTCGCCAAGTCGACGAAGTTCAGCTCGGCGTTTATTAAAATCGGGT
TGGTCGCGGATGCGGGCGGTCCATATCACCTGCGTCGACTCATGCGCGACGACCTCGCGTTAGATTGGCTCTGGAGTGGC
AGTACGATTGACTCGGAGGCCGCGCGTACATTCGGGCTCGTCACCGAGCTCGTGGAAGATGCGATGTATACGGAGCGATT
GACTTCATATGCGGAGACACTCGCTGCGAAATCATCGGTCGCTGTTCAAGGGATGAAGGCGCTCATGCGAGCCGCTTCAT
TTGAGGATGGATTGAATGAAGAAATCGAATGGCAACGGAAGTGTGGGGACACGGACGTGCACCGCCAAGCGATGCAGGCA
TTCTTGATGAAATGA

Upstream 100 bases:

>100_bases
CTTCCCGGCAATTGAACTTCAAAAAACTTTTCAGTAAAGGAAGGAGTTTGAAGCAATGATGAAGAAATGAACAGTGATTC
ATTTTGAAGGGGGAATGGAA

Downstream 100 bases:

>100_bases
AAAAAGCGGCCGCGGCCGCTTTTTTACGTGGTTGATTTTGCTTCGAACTGGAAGCCTTTTTGTTGCCACGTCCCGTATTT
CCAACGACGGAACGCGAAGA

Product: Enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MEMIQLTTHNGVGWLKLNRPEKLNALNETLLREMKTAIDTFEQDDAVRVIVLVGEGRAFSSGQDLTIESDADYGEYLEDV
YHPLVRALFSSRKPLIAGIHGVVAGAGLSLALAADVRIVAKSTKFSSAFIKIGLVADAGGPYHLRRLMRDDLALDWLWSG
STIDSEAARTFGLVTELVEDAMYTERLTSYAETLAAKSSVAVQGMKALMRAASFEDGLNEEIEWQRKCGDTDVHRQAMQA
FLMK

Sequences:

>Translated_244_residues
MEMIQLTTHNGVGWLKLNRPEKLNALNETLLREMKTAIDTFEQDDAVRVIVLVGEGRAFSSGQDLTIESDADYGEYLEDV
YHPLVRALFSSRKPLIAGIHGVVAGAGLSLALAADVRIVAKSTKFSSAFIKIGLVADAGGPYHLRRLMRDDLALDWLWSG
STIDSEAARTFGLVTELVEDAMYTERLTSYAETLAAKSSVAVQGMKALMRAASFEDGLNEEIEWQRKCGDTDVHRQAMQA
FLMK
>Mature_244_residues
MEMIQLTTHNGVGWLKLNRPEKLNALNETLLREMKTAIDTFEQDDAVRVIVLVGEGRAFSSGQDLTIESDADYGEYLEDV
YHPLVRALFSSRKPLIAGIHGVVAGAGLSLALAADVRIVAKSTKFSSAFIKIGLVADAGGPYHLRRLMRDDLALDWLWSG
STIDSEAARTFGLVTELVEDAMYTERLTSYAETLAAKSSVAVQGMKALMRAASFEDGLNEEIEWQRKCGDTDVHRQAMQA
FLMK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=240, Percent_Identity=31.6666666666667, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI70995211, Length=229, Percent_Identity=28.82096069869, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI37594469, Length=215, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI37594471, Length=215, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542718, Length=201, Percent_Identity=25.8706467661692, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI45643119, Length=216, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI260275230, Length=216, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI260274832, Length=216, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI68989263, Length=171, Percent_Identity=30.4093567251462, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI20127408, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=253, Percent_Identity=33.9920948616601, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=29.9595141700405, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI221142681, Length=218, Percent_Identity=28.8990825688073, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788597, Length=209, Percent_Identity=27.7511961722488, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=237, Percent_Identity=32.4894514767932, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17554946, Length=229, Percent_Identity=26.6375545851528, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=237, Percent_Identity=27.4261603375527, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=194, Percent_Identity=28.8659793814433, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=234, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=179, Percent_Identity=31.2849162011173, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17549921, Length=210, Percent_Identity=25.7142857142857, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=254, Percent_Identity=25.1968503937008, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=25.7777777777778, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25144276, Length=200, Percent_Identity=29.5, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=210, Percent_Identity=29.5238095238095, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=200, Percent_Identity=26, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=189, Percent_Identity=23.2804232804233, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129971, Length=224, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24653477, Length=224, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=31.1627906976744, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24654903, Length=185, Percent_Identity=25.4054054054054, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24653139, Length=205, Percent_Identity=26.3414634146341, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24650670, Length=170, Percent_Identity=32.9411764705882, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21357171, Length=176, Percent_Identity=28.9772727272727, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19922422, Length=206, Percent_Identity=24.2718446601942, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26887; Mature: 26887

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMIQLTTHNGVGWLKLNRPEKLNALNETLLREMKTAIDTFEQDDAVRVIVLVGEGRAFS
CCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
SGQDLTIESDADYGEYLEDVYHPLVRALFSSRKPLIAGIHGVVAGAGLSLALAADVRIVA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHHHCEEEEE
KSTKFSSAFIKIGLVADAGGPYHLRRLMRDDLALDWLWSGSTIDSEAARTFGLVTELVED
ECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHH
AMYTERLTSYAETLAAKSSVAVQGMKALMRAASFEDGLNEEIEWQRKCGDTDVHRQAMQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHH
FLMK
HHCC
>Mature Secondary Structure
MEMIQLTTHNGVGWLKLNRPEKLNALNETLLREMKTAIDTFEQDDAVRVIVLVGEGRAFS
CCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
SGQDLTIESDADYGEYLEDVYHPLVRALFSSRKPLIAGIHGVVAGAGLSLALAADVRIVA
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEHHHCEEEEE
KSTKFSSAFIKIGLVADAGGPYHLRRLMRDDLALDWLWSGSTIDSEAARTFGLVTELVED
ECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHH
AMYTERLTSYAETLAAKSSVAVQGMKALMRAASFEDGLNEEIEWQRKCGDTDVHRQAMQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHH
FLMK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]