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The map label for this gene is cdd [H]

Identifier: 229918109

GI number: 229918109

Start: 2341224

End: 2341631

Strand: Direct

Name: cdd [H]

Synonym: EAT1b_2389

Alternate gene names: 229918109

Gene position: 2341224-2341631 (Clockwise)

Preceding gene: 229918108

Following gene: 229918111

Centisome position: 78.04

GC content: 48.77

Gene sequence:

>408_bases
ATGATCTCACAAGAACGCGTACAAGAACTCGTCCATAAAGCGATCGAAGCGCGCAAACGCGCCTATACACCGTATTCAAA
GTTTAATGTGGGGGCTGTCGTCATCGATACATCCGGAAACGAAATTACCGGGTGTAACGTGGAGAACGCCTCGTACGGAC
TATCGATGTGTGCCGAACGCACAGCCATTTTTAAAGCCGTGTCAGAAGGTAGTGACGCGATTGAAACGGTCGTCGTCGTC
GGTGACACGGAAGGCCCGATTTCGCCATGTGGTGCATGTCGCCAAGTGATCGCTGAATTCGCTGGCGAAGACTTCACGTT
GATTCTTGCGAACTTGAACGGTGATACGAAAGTGATGACGAAAGAAGAGATGTTGCCTTACGGATTTTCACCAAAAGATT
TAACATAA

Upstream 100 bases:

>100_bases
AATATTGACGAGTCCGTGAAAAGACTTGTCGCGTAAGCGTTTTCACGCTATAGTTCAGATGTCAGACTTCTTTTCAAAAA
TAGAAGCGGAGGAACATCCT

Downstream 100 bases:

>100_bases
ACAAGCTGCGGACAAACGTCCGCAGCTTGTTTATTTGTCTTTATATTTCTTTTCACTCACCGAGTCATCTTTCGAGTGAC
GTTTATTCTTTTCATCCTTC

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MISQERVQELVHKAIEARKRAYTPYSKFNVGAVVIDTSGNEITGCNVENASYGLSMCAERTAIFKAVSEGSDAIETVVVV
GDTEGPISPCGACRQVIAEFAGEDFTLILANLNGDTKVMTKEEMLPYGFSPKDLT

Sequences:

>Translated_135_residues
MISQERVQELVHKAIEARKRAYTPYSKFNVGAVVIDTSGNEITGCNVENASYGLSMCAERTAIFKAVSEGSDAIETVVVV
GDTEGPISPCGACRQVIAEFAGEDFTLILANLNGDTKVMTKEEMLPYGFSPKDLT
>Mature_135_residues
MISQERVQELVHKAIEARKRAYTPYSKFNVGAVVIDTSGNEITGCNVENASYGLSMCAERTAIFKAVSEGSDAIETVVVV
GDTEGPISPCGACRQVIAEFAGEDFTLILANLNGDTKVMTKEEMLPYGFSPKDLT

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=134, Percent_Identity=47.0149253731343, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=45.6692913385827, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17551074, Length=128, Percent_Identity=46.875, Blast_Score=115, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6323274, Length=137, Percent_Identity=39.4160583941606, Blast_Score=103, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24582741, Length=129, Percent_Identity=44.1860465116279, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19920920, Length=121, Percent_Identity=45.4545454545455, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24582744, Length=105, Percent_Identity=41.9047619047619, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14529; Mature: 14529

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISQERVQELVHKAIEARKRAYTPYSKFNVGAVVIDTSGNEITGCNVENASYGLSMCAER
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHH
TAIFKAVSEGSDAIETVVVVGDTEGPISPCGACRQVIAEFAGEDFTLILANLNGDTKVMT
HHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEE
KEEMLPYGFSPKDLT
HHHCCCCCCCCCCCC
>Mature Secondary Structure
MISQERVQELVHKAIEARKRAYTPYSKFNVGAVVIDTSGNEITGCNVENASYGLSMCAER
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHH
TAIFKAVSEGSDAIETVVVVGDTEGPISPCGACRQVIAEFAGEDFTLILANLNGDTKVMT
HHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEE
KEEMLPYGFSPKDLT
HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]