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The map label for this gene is fnr [H]

Identifier: 229918060

GI number: 229918060

Start: 2294276

End: 2294986

Strand: Direct

Name: fnr [H]

Synonym: EAT1b_2339

Alternate gene names: 229918060

Gene position: 2294276-2294986 (Clockwise)

Preceding gene: 229918059

Following gene: 229918061

Centisome position: 76.48

GC content: 45.99

Gene sequence:

>711_bases
ATGTCAATGCAATGTGGAACGACCCAACCGAACAGTTTTGTATTCTCAGACGAAACGAAACAGCTGTTACTCGAAATGAT
GACGCTTCAACATCACCCAAAAGCGAGTATCGTGTGTTGGGAAGGTGAAAAGTGTGATAAGTTCTTTTACTTGAAGAGTG
GTTCTGTCAAATTCACGAAAATCACGAAAAAGGGAAATCCACTCGTCATGTTCATGTATGGATCGGATGATTTCTTTGGT
GAGTTTGACATCGTGGAGACATTCCCTAGTTCGTATAGCATCGAAACGACCGAAGAGAGTACAATCGGGACGATTTCAAA
ACGAGAATTAGAGTCGCTCATGCAGCGCGATATCCGTTTTGCCGGAGAAATCTTGCGCTGGACATCGATGATGCGTAAGC
ACTCCGAAATGAAAGTGCGCGACTTATTGTTGTACGGAAAACCTGGTGCATTGGCTTCGACGTTGCTTCGAATGGCCGCA
ATGCATGGAGTGGAGGAAGAAGATGCAATCGTGATTCCTCGTCATCCGTCTGACGGAGAACTCGGACAGTTGATTGGTGC
ACCGCGTGAGACGGTGAATCGGTTGATCAGTCAGTGGCGAAAAGAAGGGGTCATCAGCACAACAACGAAATCAATCATCA
TTCGCGATGTCGACTTTTTAAAAGAGCTGTGCCATTGCGAAGGCTGTCCGGCAGGAATATGTCGTTTATAA

Upstream 100 bases:

>100_bases
TTTGAAATGTCACATACTTTTATGATACTCCCTGTCACACTCCTGTATAATAAAGTCATAAATGGAACGGACGAATGAAA
CGTGGAGGGAGCACCGACCT

Downstream 100 bases:

>100_bases
ACCGCCCCATGTGGAGGCGGTTTTTTTGTGGATTGGTTTTATGCAAATGTGAACTTTATGTGTTGAAACTACGCAAAATT
GATGTGATTGTCACTTTTGG

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSMQCGTTQPNSFVFSDETKQLLLEMMTLQHHPKASIVCWEGEKCDKFFYLKSGSVKFTKITKKGNPLVMFMYGSDDFFG
EFDIVETFPSSYSIETTEESTIGTISKRELESLMQRDIRFAGEILRWTSMMRKHSEMKVRDLLLYGKPGALASTLLRMAA
MHGVEEEDAIVIPRHPSDGELGQLIGAPRETVNRLISQWRKEGVISTTTKSIIIRDVDFLKELCHCEGCPAGICRL

Sequences:

>Translated_236_residues
MSMQCGTTQPNSFVFSDETKQLLLEMMTLQHHPKASIVCWEGEKCDKFFYLKSGSVKFTKITKKGNPLVMFMYGSDDFFG
EFDIVETFPSSYSIETTEESTIGTISKRELESLMQRDIRFAGEILRWTSMMRKHSEMKVRDLLLYGKPGALASTLLRMAA
MHGVEEEDAIVIPRHPSDGELGQLIGAPRETVNRLISQWRKEGVISTTTKSIIIRDVDFLKELCHCEGCPAGICRL
>Mature_235_residues
SMQCGTTQPNSFVFSDETKQLLLEMMTLQHHPKASIVCWEGEKCDKFFYLKSGSVKFTKITKKGNPLVMFMYGSDDFFGE
FDIVETFPSSYSIETTEESTIGTISKRELESLMQRDIRFAGEILRWTSMMRKHSEMKVRDLLLYGKPGALASTLLRMAAM
HGVEEEDAIVIPRHPSDGELGQLIGAPRETVNRLISQWRKEGVISTTTKSIIIRDVDFLKELCHCEGCPAGICRL

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=211, Percent_Identity=25.1184834123223, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26747; Mature: 26616

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00888 CNMP_BINDING_1 ; PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMQCGTTQPNSFVFSDETKQLLLEMMTLQHHPKASIVCWEGEKCDKFFYLKSGSVKFTK
CCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCEEEEE
ITKKGNPLVMFMYGSDDFFGEFDIVETFPSSYSIETTEESTIGTISKRELESLMQRDIRF
EECCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEECCCCCHHCCCCHHHHHHHHHHHHHH
AGEILRWTSMMRKHSEMKVRDLLLYGKPGALASTLLRMAAMHGVEEEDAIVIPRHPSDGE
HHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
LGQLIGAPRETVNRLISQWRKEGVISTTTKSIIIRDVDFLKELCHCEGCPAGICRL
HHHHHCCCHHHHHHHHHHHHHCCCEEECHHHHEEHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SMQCGTTQPNSFVFSDETKQLLLEMMTLQHHPKASIVCWEGEKCDKFFYLKSGSVKFTK
CCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCEEEEE
ITKKGNPLVMFMYGSDDFFGEFDIVETFPSSYSIETTEESTIGTISKRELESLMQRDIRF
EECCCCCEEEEEECCCCCCCCCHHHHHCCCCCEEECCCCCHHCCCCHHHHHHHHHHHHHH
AGEILRWTSMMRKHSEMKVRDLLLYGKPGALASTLLRMAAMHGVEEEDAIVIPRHPSDGE
HHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
LGQLIGAPRETVNRLISQWRKEGVISTTTKSIIIRDVDFLKELCHCEGCPAGICRL
HHHHHCCCHHHHHHHHHHHHHCCCEEECHHHHEEHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]