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The map label for this gene is deoD

Identifier: 229918057

GI number: 229918057

Start: 2290606

End: 2291319

Strand: Direct

Name: deoD

Synonym: EAT1b_2336

Alternate gene names: 229918057

Gene position: 2290606-2291319 (Clockwise)

Preceding gene: 229918056

Following gene: 229918058

Centisome position: 76.36

GC content: 49.3

Gene sequence:

>714_bases
ATGAGTGTACACATTGGAGCTCAAGAAGGACAAATTGCAGAAACGGTATTACTTCCAGGGGATCCGCTTCGCGCCAAGTA
TATCGCGGAAACGTTTTTAGAAGACGTCGAATTATATAACGAAGTTCGTGGCATGTACGGCTTCACGGGAACATACAAAG
GCAAACGGATCTCGGTTCAAGGTACGGGGATGGGTGTCCCATCGATGTCGATTTACGTGAATGAACTCATCATGTCGTAC
GGTGCTAAAAACTTGATCCGTGTCGGAACAGCGGGCGGAATTCAAGAAGATGTTAAAGTGCGTGACGTTGTCATCGCGAT
GAGCGCATCAAGTGAAATGGGACAAAACCGCGTCCGTTTCAACGGCATGGACTATGCGCCGACAGCGACGTTCGACCTCC
TACATCGTGCGTATATGAACGCAGAGAAGGCGGGTATCCCGGTCAAAGTCGGACAAATCTTCACGGCTGACCAATTCTAT
CAAGATGATTTCCATCACTTCAAGAAATGGGCGGACTTCGGTTGCCTCGCGATCGAGATGGAAGCAGCAGGTCTTTACAC
GCTTGCAGCGAAACACAAAGTGAACGCGTTGACGATCCTCACAATCTCTGACCACTTGTTGACGGGTGAAGAGACGACTT
CAGAAGAGCGTCAATCGACGTTCGATGAAATGATTCGTGTCGCTCTCGACACAGCCGTCGAAGTGACAAACTAA

Upstream 100 bases:

>100_bases
CGACAAATATTTCCGAAAGGTCTTTAAAAAACAAGTCGGTGTTACTCCGAACGAATTTCGGGAACAAGTTCAACGACAAG
CTTAAAGGAGGAATTCAAAC

Downstream 100 bases:

>100_bases
GCGATTTTCCCTATAGCCTTTGGCTGTAGGGATTTTTTGTGTCTAAACCCATTCATCCCTATGAAACGGTTGGAGCTCCA
GCTAGACTAAGAATAAGATC

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSVHIGAQEGQIAETVLLPGDPLRAKYIAETFLEDVELYNEVRGMYGFTGTYKGKRISVQGTGMGVPSMSIYVNELIMSY
GAKNLIRVGTAGGIQEDVKVRDVVIAMSASSEMGQNRVRFNGMDYAPTATFDLLHRAYMNAEKAGIPVKVGQIFTADQFY
QDDFHHFKKWADFGCLAIEMEAAGLYTLAAKHKVNALTILTISDHLLTGEETTSEERQSTFDEMIRVALDTAVEVTN

Sequences:

>Translated_237_residues
MSVHIGAQEGQIAETVLLPGDPLRAKYIAETFLEDVELYNEVRGMYGFTGTYKGKRISVQGTGMGVPSMSIYVNELIMSY
GAKNLIRVGTAGGIQEDVKVRDVVIAMSASSEMGQNRVRFNGMDYAPTATFDLLHRAYMNAEKAGIPVKVGQIFTADQFY
QDDFHHFKKWADFGCLAIEMEAAGLYTLAAKHKVNALTILTISDHLLTGEETTSEERQSTFDEMIRVALDTAVEVTN
>Mature_236_residues
SVHIGAQEGQIAETVLLPGDPLRAKYIAETFLEDVELYNEVRGMYGFTGTYKGKRISVQGTGMGVPSMSIYVNELIMSYG
AKNLIRVGTAGGIQEDVKVRDVVIAMSASSEMGQNRVRFNGMDYAPTATFDLLHRAYMNAEKAGIPVKVGQIFTADQFYQ
DDFHHFKKWADFGCLAIEMEAAGLYTLAAKHKVNALTILTISDHLLTGEETTSEERQSTFDEMIRVALDTAVEVTN

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=230, Percent_Identity=53.0434782608696, Blast_Score=254, Evalue=3e-69,
Organism=Escherichia coli, GI1790265, Length=245, Percent_Identity=27.3469387755102, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_EXISA (C4L2Y4)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886703.1
- GeneID:   7870385
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_2336
- OMA:   SFETHAF
- ProtClustDB:   CLSK2489024
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 26136; Mature: 26005

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVHIGAQEGQIAETVLLPGDPLRAKYIAETFLEDVELYNEVRGMYGFTGTYKGKRISVQ
CEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
GTGMGVPSMSIYVNELIMSYGAKNLIRVGTAGGIQEDVKVRDVVIAMSASSEMGQNRVRF
ECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCEEE
NGMDYAPTATFDLLHRAYMNAEKAGIPVKVGQIFTADQFYQDDFHHFKKWADFGCLAIEM
CCCCCCCCHHHHHHHHHHHCHHHCCCCEEECCEEEHHHHHHHHHHHHHHHHCCCEEEEEE
EAAGLYTLAAKHKVNALTILTISDHLLTGEETTSEERQSTFDEMIRVALDTAVEVTN
ECCCEEEEECCCCCCEEEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHEEECC
>Mature Secondary Structure 
SVHIGAQEGQIAETVLLPGDPLRAKYIAETFLEDVELYNEVRGMYGFTGTYKGKRISVQ
EEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
GTGMGVPSMSIYVNELIMSYGAKNLIRVGTAGGIQEDVKVRDVVIAMSASSEMGQNRVRF
ECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCEEE
NGMDYAPTATFDLLHRAYMNAEKAGIPVKVGQIFTADQFYQDDFHHFKKWADFGCLAIEM
CCCCCCCCHHHHHHHHHHHCHHHCCCCEEECCEEEHHHHHHHHHHHHHHHHCCCEEEEEE
EAAGLYTLAAKHKVNALTILTISDHLLTGEETTSEERQSTFDEMIRVALDTAVEVTN
ECCCEEEEECCCCCCEEEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA