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The map label for this gene is ade [H]

Identifier: 229917992

GI number: 229917992

Start: 2223818

End: 2225527

Strand: Direct

Name: ade [H]

Synonym: EAT1b_2271

Alternate gene names: 229917992

Gene position: 2223818-2225527 (Clockwise)

Preceding gene: 229917989

Following gene: 229917993

Centisome position: 74.13

GC content: 52.05

Gene sequence:

>1710_bases
ATGGAAAAACAACATTTGATTGACATCGCCGCAAAGAAAAAGAAAGCGGCCGTCGTCTTTAAAGACGTCGCAGTGATTGA
CGTGTACAGTCGTGAGACGATTCGTACAGACGTCGCCATCGACGCGGGATATATCGTGGCTATTGGGGATGGGTACGATG
GGGAGGTCGAGTATCACGATCCGACCTGGACGCTTGCACCGTCCTTTATCGATTCGCACGTCCATATCGAGTCATCGATG
GTCCCCCCGCATGAATTTGCGAAAGCAGTCTTACCACTTGGTGTCACAACGGTGATTGCTGACCCACATGAGATTGCGAA
TGTGAACGGAGCACTCGGGATTGAATACATGTTGGCGGATGCGAAAGGACTTCCACTCGACGTTCGGATGATGCTTCCGA
GTTGTGTACCAGCGACACCGTTCGAACATGCAGGTGCTAAACTGTATGCAGAAGATTTGGCACCGTTTTTAGGAGATGCA
GGGGTGCATGGCCTAGGCGAAGTCATGGACTATCCATCAGTTGAAGCTGGAAGTGAAGACATGCTTCAAAAGATCGCACA
GACGGAACAAGCGGGTAAAGTGGTCGACGGACACGCATCGGGACTTGGCCCAGACCAATTGAACGTCTATCGTTCTGCAG
GAATCATGACGGACCATGAATGTACGACTGCAGAAGAGGCGATTGAGCGGGTGCGCCGTGGGTTCTATGTTCAAATTCGG
GAAGGTTCCGTCGCGCGAAACGTAGAGAAGGTGAGCCTAGCCGTTACGGAAAGCAATGCCCATCGTTTCCTTTTCTGTAC
GGATGATAAGCATTTGGATGACTTGGTCGCGGAAGGCGGGATTGACTACAATATCCGTACCGCCATCAAGCAAGGAGTTA
AGCCAGAAACGGCCTATGCCATCGCAAGTCTTCATGCCGCAGAGGCCTATGGATTAAAAGAAGTCGGGGCGATCGCACCT
GGTAAGAAAGCGAACTTCGTTATCTTGTCAGACGTCGAATCGGTAAAAATCGAACAAGTGTATGTGAATGGTACGCTCGT
CGCGGAGAAGGGGAATGCGACGTTTGAATCGGAAGGGATTGAAGTGCCGAAACCGATGAAAGGTGAGCTCGCTTTACCCG
AATTGACAGCCGAGTCGTTCCGACTTGCCGCAAGTGAAGAAGAAATCGATGTCATTCAAGTGCTTCCGAACAGCTTGTTG
ACGAAACGACAGCGTCTCACGTTCCAACCAGACGCATCAGGCGCAGATTTATCGCAGGATATCGCGACGCTTGCCGTCAT
CGAACGCCATCACGGGACAGGTCATATGGCTCTTGCCCCGGTAACGGGATTTGGCTTGAAGCGAGGTGCCCTAGCAGCCA
CGGTTGCCCATGACAGCCATAACTTGGTCGTCGCCGGAGTCAGCCCGGAGGACATGTTGCTCGCGGCGAGAACGCTTGAA
AAAGTAGGGGGAGGGGTCGTCGCCGTATCGGAAGGTGAAGTGCTTGCCGTCCTCCCGCTCGAGATTGGTGGACTGATGAC
GAAGCGACCATATCGTGAAGTGGCAGAGATTTTGGAACAGCTCAATGATGCGCTAGATGTCGTGGGAGCCCATCGTCATT
TCAATCCATACTTAACGATGTCCTTCCTCGCCTTACCGGTCATTCCAGACTTGAAATTGACCGATATGGGATTGTTCGAC
GTGACCACGTTCTCATTCATCAACGCTTGA

Upstream 100 bases:

>100_bases
AAGATATGTTATCATTGTCGCACAACTCGAAAAAGAAATTGCAACGAAAAGAATATTCTTGGTAAGATAGTTAAAATACG
TTGAATAAGGAGATCGAAAG

Downstream 100 bases:

>100_bases
CTCGGTCTAACGTATGATTTTTGTTAAGAACCGCCGATAACGATTGAATGCGTGACGGGAAGTTGGTATAGTTACGTCAA
GTTTCATCGGGTCAACATTG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MEKQHLIDIAAKKKKAAVVFKDVAVIDVYSRETIRTDVAIDAGYIVAIGDGYDGEVEYHDPTWTLAPSFIDSHVHIESSM
VPPHEFAKAVLPLGVTTVIADPHEIANVNGALGIEYMLADAKGLPLDVRMMLPSCVPATPFEHAGAKLYAEDLAPFLGDA
GVHGLGEVMDYPSVEAGSEDMLQKIAQTEQAGKVVDGHASGLGPDQLNVYRSAGIMTDHECTTAEEAIERVRRGFYVQIR
EGSVARNVEKVSLAVTESNAHRFLFCTDDKHLDDLVAEGGIDYNIRTAIKQGVKPETAYAIASLHAAEAYGLKEVGAIAP
GKKANFVILSDVESVKIEQVYVNGTLVAEKGNATFESEGIEVPKPMKGELALPELTAESFRLAASEEEIDVIQVLPNSLL
TKRQRLTFQPDASGADLSQDIATLAVIERHHGTGHMALAPVTGFGLKRGALAATVAHDSHNLVVAGVSPEDMLLAARTLE
KVGGGVVAVSEGEVLAVLPLEIGGLMTKRPYREVAEILEQLNDALDVVGAHRHFNPYLTMSFLALPVIPDLKLTDMGLFD
VTTFSFINA

Sequences:

>Translated_569_residues
MEKQHLIDIAAKKKKAAVVFKDVAVIDVYSRETIRTDVAIDAGYIVAIGDGYDGEVEYHDPTWTLAPSFIDSHVHIESSM
VPPHEFAKAVLPLGVTTVIADPHEIANVNGALGIEYMLADAKGLPLDVRMMLPSCVPATPFEHAGAKLYAEDLAPFLGDA
GVHGLGEVMDYPSVEAGSEDMLQKIAQTEQAGKVVDGHASGLGPDQLNVYRSAGIMTDHECTTAEEAIERVRRGFYVQIR
EGSVARNVEKVSLAVTESNAHRFLFCTDDKHLDDLVAEGGIDYNIRTAIKQGVKPETAYAIASLHAAEAYGLKEVGAIAP
GKKANFVILSDVESVKIEQVYVNGTLVAEKGNATFESEGIEVPKPMKGELALPELTAESFRLAASEEEIDVIQVLPNSLL
TKRQRLTFQPDASGADLSQDIATLAVIERHHGTGHMALAPVTGFGLKRGALAATVAHDSHNLVVAGVSPEDMLLAARTLE
KVGGGVVAVSEGEVLAVLPLEIGGLMTKRPYREVAEILEQLNDALDVVGAHRHFNPYLTMSFLALPVIPDLKLTDMGLFD
VTTFSFINA
>Mature_569_residues
MEKQHLIDIAAKKKKAAVVFKDVAVIDVYSRETIRTDVAIDAGYIVAIGDGYDGEVEYHDPTWTLAPSFIDSHVHIESSM
VPPHEFAKAVLPLGVTTVIADPHEIANVNGALGIEYMLADAKGLPLDVRMMLPSCVPATPFEHAGAKLYAEDLAPFLGDA
GVHGLGEVMDYPSVEAGSEDMLQKIAQTEQAGKVVDGHASGLGPDQLNVYRSAGIMTDHECTTAEEAIERVRRGFYVQIR
EGSVARNVEKVSLAVTESNAHRFLFCTDDKHLDDLVAEGGIDYNIRTAIKQGVKPETAYAIASLHAAEAYGLKEVGAIAP
GKKANFVILSDVESVKIEQVYVNGTLVAEKGNATFESEGIEVPKPMKGELALPELTAESFRLAASEEEIDVIQVLPNSLL
TKRQRLTFQPDASGADLSQDIATLAVIERHHGTGHMALAPVTGFGLKRGALAATVAHDSHNLVVAGVSPEDMLLAARTLE
KVGGGVVAVSEGEVLAVLPLEIGGLMTKRPYREVAEILEQLNDALDVVGAHRHFNPYLTMSFLALPVIPDLKLTDMGLFD
VTTFSFINA

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=578, Percent_Identity=36.5051903114187, Blast_Score=319, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 61038; Mature: 61038

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQHLIDIAAKKKKAAVVFKDVAVIDVYSRETIRTDVAIDAGYIVAIGDGYDGEVEYHD
CCCHHEEHHHHCCCCEEEEEEEEEEEEEECCCCEEEEEEECCCEEEEEECCCCCEEEEEC
PTWTLAPSFIDSHVHIESSMVPPHEFAKAVLPLGVTTVIADPHEIANVNGALGIEYMLAD
CCEEECHHHHCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHCCCCCCCEEEEEEEC
AKGLPLDVRMMLPSCVPATPFEHAGAKLYAEDLAPFLGDAGVHGLGEVMDYPSVEAGSED
CCCCCEEHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHH
MLQKIAQTEQAGKVVDGHASGLGPDQLNVYRSAGIMTDHECTTAEEAIERVRRGFYVQIR
HHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEEE
EGSVARNVEKVSLAVTESNAHRFLFCTDDKHLDDLVAEGGIDYNIRTAIKQGVKPETAYA
CCCCCCCCEEEEEEEEECCCEEEEEECCCCHHHHHHHCCCCCEEHHHHHHCCCCCHHHHH
IASLHAAEAYGLKEVGAIAPGKKANFVILSDVESVKIEQVYVNGTLVAEKGNATFESEGI
HHHHHHHHHCCHHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCEEEEECCCCEECCCCC
EVPKPMKGELALPELTAESFRLAASEEEIDVIQVLPNSLLTKRQRLTFQPDASGADLSQD
CCCCCCCCCCCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHCEEECCCCCCCCHHHH
IATLAVIERHHGTGHMALAPVTGFGLKRGALAATVAHDSHNLVVAGVSPEDMLLAARTLE
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHH
KVGGGVVAVSEGEVLAVLPLEIGGLMTKRPYREVAEILEQLNDALDVVGAHRHFNPYLTM
HHCCCEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
SFLALPVIPDLKLTDMGLFDVTTFSFINA
HHHHHCCCCCCEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MEKQHLIDIAAKKKKAAVVFKDVAVIDVYSRETIRTDVAIDAGYIVAIGDGYDGEVEYHD
CCCHHEEHHHHCCCCEEEEEEEEEEEEEECCCCEEEEEEECCCEEEEEECCCCCEEEEEC
PTWTLAPSFIDSHVHIESSMVPPHEFAKAVLPLGVTTVIADPHEIANVNGALGIEYMLAD
CCEEECHHHHCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHCCCCCCCEEEEEEEC
AKGLPLDVRMMLPSCVPATPFEHAGAKLYAEDLAPFLGDAGVHGLGEVMDYPSVEAGSED
CCCCCEEHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHH
MLQKIAQTEQAGKVVDGHASGLGPDQLNVYRSAGIMTDHECTTAEEAIERVRRGFYVQIR
HHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEEEE
EGSVARNVEKVSLAVTESNAHRFLFCTDDKHLDDLVAEGGIDYNIRTAIKQGVKPETAYA
CCCCCCCCEEEEEEEEECCCEEEEEECCCCHHHHHHHCCCCCEEHHHHHHCCCCCHHHHH
IASLHAAEAYGLKEVGAIAPGKKANFVILSDVESVKIEQVYVNGTLVAEKGNATFESEGI
HHHHHHHHHCCHHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCEEEEECCCCEECCCCC
EVPKPMKGELALPELTAESFRLAASEEEIDVIQVLPNSLLTKRQRLTFQPDASGADLSQD
CCCCCCCCCCCCCCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHCEEECCCCCCCCHHHH
IATLAVIERHHGTGHMALAPVTGFGLKRGALAATVAHDSHNLVVAGVSPEDMLLAARTLE
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHH
KVGGGVVAVSEGEVLAVLPLEIGGLMTKRPYREVAEILEQLNDALDVVGAHRHFNPYLTM
HHCCCEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
SFLALPVIPDLKLTDMGLFDVTTFSFINA
HHHHHCCCCCCEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA