Click here to switch to the map view.

The map label for this gene is murB [H]

Identifier: 229917749

GI number: 229917749

Start: 1979046

End: 1979966

Strand: Direct

Name: murB [H]

Synonym: EAT1b_2027

Alternate gene names: 229917749

Gene position: 1979046-1979966 (Clockwise)

Preceding gene: 229917748

Following gene: 229917754

Centisome position: 65.97

GC content: 49.95

Gene sequence:

>921_bases
ATGAGCTTTTTACAGCAACTCCAGATGATCATTCCGGCCGAGCGCGTCCTTCAAGACGAGCCGTTGTCGGCACACACGTA
TACAAAACTAGGCGGTAAGGCAGATTACTTCGTGGCTCCACACACGTACGAAGAAGTACAGGCCGTCTTACAACTGGCCC
ATCAAGAAGCGATGCCGTTTATGATTCTTGGCTTCGGTTCAAACTTGATCGTTCGCGATGGTGGCATCCGTGGAATCGTT
TTGAACTTGAATGAACTCGACTCGATTCGTCGAGAAGGGAATCAAATGATTGCGCAGGCAGGAGCGGCGATTATCGACGT
CTCACGTCAAGCATTAGCAGAGGGGTTATCCGGCCTCGAATTTGCATGTGGGATCCCTGGGACGGTCGGTGGTGCCGTCT
ACATGAACGCAGGTGCATACGGCGGAGAGACGAAGGATGTCATCACATCTGCGACGGTGTTGACGCAGGATGGTCAAGTA
CTTCATTTATCTAAAGATGAACTCGATCTTGACTACCGAACGAGCCGTGTCTCGAAAGAGGGCTTGATCGTACTCGAGGC
GACGTTCGAACTAGAACCGAAAAACTATGAATTGATCAAAGAAGTCATGGACGACTTGACGTATAAACGGGAATCGAAAC
AACCGCTTGAATATCCTTCATGTGGAAGTGTGTTCAAACGTCCGCCTGGCTATTTTGCCGGCAAGTTGATTCAAGACTCT
GGTCTACAAGGCAAACGCATCGGAGGGGCGGAAGTCTCGCTCAAACATGCGGGCTTCATCGTCAATATCGATGAGGCGAC
GGCGACTGAGTACATTTCACTCATCCGTCACGTCCAGGCGACCGTTAAAGAGAAATTCGAAGTGGAATTAGAGCCGGAAG
TGAAAATCATCGGGGAAGATATCGCCGTTGAAAACGCATAA

Upstream 100 bases:

>100_bases
ATACTGTGATTCGTACTGAAACCATTCAGTGACGTGCTCGGAACGAATGAGATGGGACCGAGACACTGATTAAATAGAAC
ATAAAGGATTGAGTGAACGC

Downstream 100 bases:

>100_bases
CGCATAATAAAGAAGGAATCGGACGATGGCGTTCGATTCCTTCTTTTTGGTATAGAGAAAAGACGATGAGAACGTGCATC
TCATCGTCTTAAGGGTTAAG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSFLQQLQMIIPAERVLQDEPLSAHTYTKLGGKADYFVAPHTYEEVQAVLQLAHQEAMPFMILGFGSNLIVRDGGIRGIV
LNLNELDSIRREGNQMIAQAGAAIIDVSRQALAEGLSGLEFACGIPGTVGGAVYMNAGAYGGETKDVITSATVLTQDGQV
LHLSKDELDLDYRTSRVSKEGLIVLEATFELEPKNYELIKEVMDDLTYKRESKQPLEYPSCGSVFKRPPGYFAGKLIQDS
GLQGKRIGGAEVSLKHAGFIVNIDEATATEYISLIRHVQATVKEKFEVELEPEVKIIGEDIAVENA

Sequences:

>Translated_306_residues
MSFLQQLQMIIPAERVLQDEPLSAHTYTKLGGKADYFVAPHTYEEVQAVLQLAHQEAMPFMILGFGSNLIVRDGGIRGIV
LNLNELDSIRREGNQMIAQAGAAIIDVSRQALAEGLSGLEFACGIPGTVGGAVYMNAGAYGGETKDVITSATVLTQDGQV
LHLSKDELDLDYRTSRVSKEGLIVLEATFELEPKNYELIKEVMDDLTYKRESKQPLEYPSCGSVFKRPPGYFAGKLIQDS
GLQGKRIGGAEVSLKHAGFIVNIDEATATEYISLIRHVQATVKEKFEVELEPEVKIIGEDIAVENA
>Mature_305_residues
SFLQQLQMIIPAERVLQDEPLSAHTYTKLGGKADYFVAPHTYEEVQAVLQLAHQEAMPFMILGFGSNLIVRDGGIRGIVL
NLNELDSIRREGNQMIAQAGAAIIDVSRQALAEGLSGLEFACGIPGTVGGAVYMNAGAYGGETKDVITSATVLTQDGQVL
HLSKDELDLDYRTSRVSKEGLIVLEATFELEPKNYELIKEVMDDLTYKRESKQPLEYPSCGSVFKRPPGYFAGKLIQDSG
LQGKRIGGAEVSLKHAGFIVNIDEATATEYISLIRHVQATVKEKFEVELEPEVKIIGEDIAVENA

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33433; Mature: 33301

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLQQLQMIIPAERVLQDEPLSAHTYTKLGGKADYFVAPHTYEEVQAVLQLAHQEAMPF
CCHHHHHHHHCCHHHHHCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCE
MILGFGSNLIVRDGGIRGIVLNLNELDSIRREGNQMIAQAGAAIIDVSRQALAEGLSGLE
EEEECCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCE
FACGIPGTVGGAVYMNAGAYGGETKDVITSATVLTQDGQVLHLSKDELDLDYRTSRVSKE
EECCCCCCCCCEEEEECCCCCCCCHHHHEEEEEEECCCCEEEECCCCCCCCHHHHHCCCC
GLIVLEATFELEPKNYELIKEVMDDLTYKRESKQPLEYPSCGSVFKRPPGYFAGKLIQDS
CEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCC
GLQGKRIGGAEVSLKHAGFIVNIDEATATEYISLIRHVQATVKEKFEVELEPEVKIIGED
CCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECC
IAVENA
EECCCC
>Mature Secondary Structure 
SFLQQLQMIIPAERVLQDEPLSAHTYTKLGGKADYFVAPHTYEEVQAVLQLAHQEAMPF
CHHHHHHHHCCHHHHHCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCE
MILGFGSNLIVRDGGIRGIVLNLNELDSIRREGNQMIAQAGAAIIDVSRQALAEGLSGLE
EEEECCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCE
FACGIPGTVGGAVYMNAGAYGGETKDVITSATVLTQDGQVLHLSKDELDLDYRTSRVSKE
EECCCCCCCCCEEEEECCCCCCCCHHHHEEEEEEECCCCEEEECCCCCCCCHHHHHCCCC
GLIVLEATFELEPKNYELIKEVMDDLTYKRESKQPLEYPSCGSVFKRPPGYFAGKLIQDS
CEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCC
GLQGKRIGGAEVSLKHAGFIVNIDEATATEYISLIRHVQATVKEKFEVELEPEVKIIGED
CCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECC
IAVENA
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]