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The map label for this gene is nhaC [H]

Identifier: 229917717

GI number: 229917717

Start: 1949205

End: 1950581

Strand: Direct

Name: nhaC [H]

Synonym: EAT1b_1994

Alternate gene names: 229917717

Gene position: 1949205-1950581 (Clockwise)

Preceding gene: 229917712

Following gene: 229917718

Centisome position: 64.98

GC content: 53.45

Gene sequence:

>1377_bases
ATGCAGATGAAAGGAAAAGAAGCTGTATTCGTCGTGTTGATGAGCGGGATCACCTTGCTCGCACTGATGTTTTTGGCCAA
AGCGACGCCACATATGGCGATTTTTGGCACAATGGTAATGGTAGGTGGATACGCATATTATCGTTCACGCGACTTCAAAC
AGATTGAAACGGCGATGATCAACGGGATTCGTGAAGCGATCATGCCGGTATTGATTTTGTTGTTGATTGGGATGCTCATC
GGAGTATGGCAAATGTCCGGGACGGTCGCGACGATCCTCTCCATCGGTCTAAATACAATCTCTGCTGAATGGTTCTTACC
GAGTGTTTTATTAATCACGATGATCGTCTCGACCTTCACAGGAAGTGCGTTTACAACCGTCGGAACGGTCGGTGTCGCCT
TATTTGGAATCGGGACGGCACTAGGCATCTCGCCAGCGCTCGCCGCAGGTGCGATCGTATCGGGTGCCCTCTTCGGAGAC
AAGATGAGCCCGTTGTCGGATACGACGAACTTTGCGCCGGCAGTGGCGGGCGTCAAACTGTTCGACCACATTCGCTTCAT
GATGGGGACGACGATTCCAGCGTTCATCATCACGTTGATTCTATTCACGTTCCTCGGACGTAGCGGTCAAACTGCCGACA
CGGCACAAATTGCAGAGGCGCAAGCCGCGCTCAGCGGACGGTTTGACCTCTCATGGCTCACGTTGATTGCCCCTGTGCTC
GTCGCAGTGCTTGCGTTCCGTCGGATGCCGGTCTTACCGACGATGCTCGTTGGGATGTTCGCGGGTGTGTTGACGGCCGG
TTTTGTTCAAGGGAACTGGAGCATCTCGAACTGGCTCGGTGTCATGCAGTCGGGCTTCAAATCAGGTGTCGAGAATGAAA
CGATTGCGACGGTACTCGATCGTGGTGGTCTTGAATCGATGCTTTGGTCGGTCAGTCTCGTCTTGATCGCCCTTGCATTC
GGTGGCTTGTTACGTGAACTCGGTGTCTTCCAAGCCATCGTTGAATCGTTGCTCGAGCGTTTGAAGTCACCAGGGAGCTC
GGTCCTATCAGTCGTCCTCAGTTCAATCGGGGTCAACTTGCTCGCAGGAGAACAGTACTTGTCGATTCTCTTGCCGGGTC
AGGCGTTCAAGCAAGGGTTTATCGATCGTGGGATCGACCCGCGCTACTTGTCACGGGCGCTTGAGGACGGTGGAACTGTG
ATCAACCCGCTCATACCTTGGGGTGTCTCGGGAGCGTTCTTCGCAGCGACACTCGGCGTGCCTGTATTAGAATACGCCCC
ATTTGCGTTCTTCCTCTGGCTCAGCCCGGTCTTCTCCATCATCTTGGGATACGTCCGATTGGGGAAGCAACGTGAATCAC
TAAAAATCGCATCATAA

Upstream 100 bases:

>100_bases
ATAGTAAAAAACATCACTGACATGCTTTTGTGCATAAAAGCGTTTAAGCGGTTAGGCGAAATAATAAATCATAAAGATAT
AACGAAAGGAGGGGACGTCG

Downstream 100 bases:

>100_bases
CGTCCAGGTGTCCTGCCATGCAGGGCATCTTTTTTGTGTGCAAGCTACGATTTTTGAGAAAATGAAACAAATGGAGGTGG
AACGATGAAGCGACTCGAGT

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQMKGKEAVFVVLMSGITLLALMFLAKATPHMAIFGTMVMVGGYAYYRSRDFKQIETAMINGIREAIMPVLILLLIGMLI
GVWQMSGTVATILSIGLNTISAEWFLPSVLLITMIVSTFTGSAFTTVGTVGVALFGIGTALGISPALAAGAIVSGALFGD
KMSPLSDTTNFAPAVAGVKLFDHIRFMMGTTIPAFIITLILFTFLGRSGQTADTAQIAEAQAALSGRFDLSWLTLIAPVL
VAVLAFRRMPVLPTMLVGMFAGVLTAGFVQGNWSISNWLGVMQSGFKSGVENETIATVLDRGGLESMLWSVSLVLIALAF
GGLLRELGVFQAIVESLLERLKSPGSSVLSVVLSSIGVNLLAGEQYLSILLPGQAFKQGFIDRGIDPRYLSRALEDGGTV
INPLIPWGVSGAFFAATLGVPVLEYAPFAFFLWLSPVFSIILGYVRLGKQRESLKIAS

Sequences:

>Translated_458_residues
MQMKGKEAVFVVLMSGITLLALMFLAKATPHMAIFGTMVMVGGYAYYRSRDFKQIETAMINGIREAIMPVLILLLIGMLI
GVWQMSGTVATILSIGLNTISAEWFLPSVLLITMIVSTFTGSAFTTVGTVGVALFGIGTALGISPALAAGAIVSGALFGD
KMSPLSDTTNFAPAVAGVKLFDHIRFMMGTTIPAFIITLILFTFLGRSGQTADTAQIAEAQAALSGRFDLSWLTLIAPVL
VAVLAFRRMPVLPTMLVGMFAGVLTAGFVQGNWSISNWLGVMQSGFKSGVENETIATVLDRGGLESMLWSVSLVLIALAF
GGLLRELGVFQAIVESLLERLKSPGSSVLSVVLSSIGVNLLAGEQYLSILLPGQAFKQGFIDRGIDPRYLSRALEDGGTV
INPLIPWGVSGAFFAATLGVPVLEYAPFAFFLWLSPVFSIILGYVRLGKQRESLKIAS
>Mature_458_residues
MQMKGKEAVFVVLMSGITLLALMFLAKATPHMAIFGTMVMVGGYAYYRSRDFKQIETAMINGIREAIMPVLILLLIGMLI
GVWQMSGTVATILSIGLNTISAEWFLPSVLLITMIVSTFTGSAFTTVGTVGVALFGIGTALGISPALAAGAIVSGALFGD
KMSPLSDTTNFAPAVAGVKLFDHIRFMMGTTIPAFIITLILFTFLGRSGQTADTAQIAEAQAALSGRFDLSWLTLIAPVL
VAVLAFRRMPVLPTMLVGMFAGVLTAGFVQGNWSISNWLGVMQSGFKSGVENETIATVLDRGGLESMLWSVSLVLIALAF
GGLLRELGVFQAIVESLLERLKSPGSSVLSVVLSSIGVNLLAGEQYLSILLPGQAFKQGFIDRGIDPRYLSRALEDGGTV
INPLIPWGVSGAFFAATLGVPVLEYAPFAFFLWLSPVFSIILGYVRLGKQRESLKIAS

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 48701; Mature: 48701

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]