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The map label for this gene is xpt

Identifier: 229917699

GI number: 229917699

Start: 1934493

End: 1935074

Strand: Direct

Name: xpt

Synonym: EAT1b_1976

Alternate gene names: 229917699

Gene position: 1934493-1935074 (Clockwise)

Preceding gene: 229917691

Following gene: 229917700

Centisome position: 64.49

GC content: 52.92

Gene sequence:

>582_bases
ATGAAGCAGTTAGAAGACAAAATCCGTGAAGAGGGTCGGGCCTTATCCGACCAAGTGTTGAAAGTTGACGCCTTCTTGAA
TCATCAGGTCGACCCGGTACTTATGCAAGCCATCGGCAAAGAATTCGCAGAACGTTTCAAAGACGCTCAAATCGACCGCA
TCGTCACACTCGAATCGAGCGGGATTGCCCCAGCGATGATGACGGCGCTTGAGATGGACATCCCGTTCGTATTCGCGCGT
AAACGGAAATCGCTGACGCTCCAAGACGACCTCGTCGAAGCGGATGTTTATTCGTTCACGAAACAGGAGACGAACCGCAT
CAGCTTGAGCCGACGTTTCGTCTTACCAGGCGAACGCGTTCTCGTCATCGATGACTTCCTCGCGAACGGGGAAGCGGCAC
TCGGGCTGACACAACTCGTCGAAGCGGCAGGTGCAGAAGTTTCAGGTGTTGGCATCGTCATCGAAAAATCGTTCCAACTA
GGGCGCGATAAACTGATTGAGCGTGGTTATCGCGTCGAATCGCTAGCGCGCGTCGCGAAATTAGAGAAAGACCATATCTC
GTTCGTGGAGGTCGTTCGATGA

Upstream 100 bases:

>100_bases
CTACGGGTGGCGCTTGTCGTATGCTATCGTTGATTTCCATGCGGTTCGTTGCCTCCCGATGAGGGGTGACGAATCGCATT
TTTTAATGGAGGGGACAACA

Downstream 100 bases:

>100_bases
ATACATTTAAGACGGCAAGTCTCGGATTTCAGCATCTGCTCGCCATGTACACGGGAGCAGCCATCGTCCCGCTCATCGTC
GGTGGTGCCATCGGGCTTGG

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKQLEDKIREEGRALSDQVLKVDAFLNHQVDPVLMQAIGKEFAERFKDAQIDRIVTLESSGIAPAMMTALEMDIPFVFAR
KRKSLTLQDDLVEADVYSFTKQETNRISLSRRFVLPGERVLVIDDFLANGEAALGLTQLVEAAGAEVSGVGIVIEKSFQL
GRDKLIERGYRVESLARVAKLEKDHISFVEVVR

Sequences:

>Translated_193_residues
MKQLEDKIREEGRALSDQVLKVDAFLNHQVDPVLMQAIGKEFAERFKDAQIDRIVTLESSGIAPAMMTALEMDIPFVFAR
KRKSLTLQDDLVEADVYSFTKQETNRISLSRRFVLPGERVLVIDDFLANGEAALGLTQLVEAAGAEVSGVGIVIEKSFQL
GRDKLIERGYRVESLARVAKLEKDHISFVEVVR
>Mature_193_residues
MKQLEDKIREEGRALSDQVLKVDAFLNHQVDPVLMQAIGKEFAERFKDAQIDRIVTLESSGIAPAMMTALEMDIPFVFAR
KRKSLTLQDDLVEADVYSFTKQETNRISLSRRFVLPGERVLVIDDFLANGEAALGLTQLVEAAGAEVSGVGIVIEKSFQL
GRDKLIERGYRVESLARVAKLEKDHISFVEVVR

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_EXISA (C4L0T7)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002886345.1
- ProteinModelPortal:   C4L0T7
- GeneID:   7869186
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_1976
- OMA:   ATVYSFT
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21635; Mature: 21635

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLEDKIREEGRALSDQVLKVDAFLNHQVDPVLMQAIGKEFAERFKDAQIDRIVTLESS
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
GIAPAMMTALEMDIPFVFARKRKSLTLQDDLVEADVYSFTKQETNRISLSRRFVLPGERV
CCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEE
LVIDDFLANGEAALGLTQLVEAAGAEVSGVGIVIEKSFQLGRDKLIERGYRVESLARVAK
EEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHCCHHHHHHCCCCHHHHHHHHH
LEKDHISFVEVVR
HHHHHHHHHHHCC
>Mature Secondary Structure
MKQLEDKIREEGRALSDQVLKVDAFLNHQVDPVLMQAIGKEFAERFKDAQIDRIVTLESS
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
GIAPAMMTALEMDIPFVFARKRKSLTLQDDLVEADVYSFTKQETNRISLSRRFVLPGERV
CCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEE
LVIDDFLANGEAALGLTQLVEAAGAEVSGVGIVIEKSFQLGRDKLIERGYRVESLARVAK
EEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHCCHHHHHHCCCCHHHHHHHHH
LEKDHISFVEVVR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA