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The map label for this gene is ykvZ [H]

Identifier: 229917688

GI number: 229917688

Start: 1925062

End: 1926021

Strand: Direct

Name: ykvZ [H]

Synonym: EAT1b_1965

Alternate gene names: 229917688

Gene position: 1925062-1926021 (Clockwise)

Preceding gene: 229917687

Following gene: 229917689

Centisome position: 64.17

GC content: 51.04

Gene sequence:

>960_bases
ATGGCAAACATTCGAGATATCGCAAAGCACGCTGACGTTTCGGTGACGACGGTCTCACGCGTCCTGAACGAGCATCCGTA
CGTATCGAAAGAAAAACGGACCCGTGTACATGCGGCAATGAAGGAGCTCGGGTATTTGCGAAATCAACAGGCGTTGACGT
TGTCGACAGGGAAGACGCAACGAATCGTCGTCATCCTACCTTATATGGATCATCCTTATTACGGTTTCTTCGTTAATGGG
CTCGCCAAGGCGGCGCTCGAGCACGATTATCGCCTCGTCATGTGGCAGACGGAGTATAAACTGAGCGAGGAACGACAAGC
GCTCGATTTATTGAAGCACCGTGAAGTCGATGGGGCAATCGTCTTGTCTCATGAGATGTCCTTTAAGGAAATGGAGACAT
ATCGCGCGTATGGACCGATCGCTGTGGCGACCGTCGGTGCACCGGAGACAATTTCGTCGATCCATGTCGATCATTACGCG
TCGTTCGTATCAGGTATTCGTGTGTTACAGCAATACGGATATGAAGAGATTGGAATCATCTTGTCAAGAAGCCATAGTCC
AAGTTCCCTTGCGCGTCAGCAAGCCTATTTCGATGAAGTAGCGCATGCGCGTGAGCAATGGATTTGGACGGGCTATTTGA
CGAGTGAGGACGGTATTCGGCTAGCTGAAACGTTCCTCTCTCAAAAAGAGCGTCCTCGAGCGCTCTTTTTCTCGTCCGAT
TATGTCGCCCTCGGATTTTTAGGAGAGATGCAACGGCGAGACATCAAGATTCCTCAGGAAGTCGCCATGCTCGGGTTTGA
CGGACATCCGATCGGTCATGCATTCGGACTGTCGACGATGCTCTCACCGAATGAAGAAATCGGGCGACGCCTATTTGAAA
CGACGCTCGCTGAAATGAATGGTGCGCAACCGGAAACGCATGGCATGACAGTGAGCTATCAAGTTGGCACCACACTTTAG

Upstream 100 bases:

>100_bases
CTCGTTCAAGCGATTCGTTGTCAAGTCGTCGAAAGAGGTGACAGTCAGCAAGCAGAGTGGGTACACTATATGCAAAGACT
GACAAGTTGAGGTGAGATGA

Downstream 100 bases:

>100_bases
GCAACTTCCTCGCTCGACTCTTTTGAAACGTTTAGAATGAAAGGAGTAGTCGAGAGGAGGAGATGTTATGAAGATTCAAG
TAACAGCAGAAGCGCTCCAA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MANIRDIAKHADVSVTTVSRVLNEHPYVSKEKRTRVHAAMKELGYLRNQQALTLSTGKTQRIVVILPYMDHPYYGFFVNG
LAKAALEHDYRLVMWQTEYKLSEERQALDLLKHREVDGAIVLSHEMSFKEMETYRAYGPIAVATVGAPETISSIHVDHYA
SFVSGIRVLQQYGYEEIGIILSRSHSPSSLARQQAYFDEVAHAREQWIWTGYLTSEDGIRLAETFLSQKERPRALFFSSD
YVALGFLGEMQRRDIKIPQEVAMLGFDGHPIGHAFGLSTMLSPNEEIGRRLFETTLAEMNGAQPETHGMTVSYQVGTTL

Sequences:

>Translated_319_residues
MANIRDIAKHADVSVTTVSRVLNEHPYVSKEKRTRVHAAMKELGYLRNQQALTLSTGKTQRIVVILPYMDHPYYGFFVNG
LAKAALEHDYRLVMWQTEYKLSEERQALDLLKHREVDGAIVLSHEMSFKEMETYRAYGPIAVATVGAPETISSIHVDHYA
SFVSGIRVLQQYGYEEIGIILSRSHSPSSLARQQAYFDEVAHAREQWIWTGYLTSEDGIRLAETFLSQKERPRALFFSSD
YVALGFLGEMQRRDIKIPQEVAMLGFDGHPIGHAFGLSTMLSPNEEIGRRLFETTLAEMNGAQPETHGMTVSYQVGTTL
>Mature_318_residues
ANIRDIAKHADVSVTTVSRVLNEHPYVSKEKRTRVHAAMKELGYLRNQQALTLSTGKTQRIVVILPYMDHPYYGFFVNGL
AKAALEHDYRLVMWQTEYKLSEERQALDLLKHREVDGAIVLSHEMSFKEMETYRAYGPIAVATVGAPETISSIHVDHYAS
FVSGIRVLQQYGYEEIGIILSRSHSPSSLARQQAYFDEVAHAREQWIWTGYLTSEDGIRLAETFLSQKERPRALFFSSDY
VALGFLGEMQRRDIKIPQEVAMLGFDGHPIGHAFGLSTMLSPNEEIGRRLFETTLAEMNGAQPETHGMTVSYQVGTTL

Specific function: This Protein Negatively Controls The Transcription Initiation Of Genes Such As Deocabd, Udp, And Cdd Encoding Catabolizing Enzymes And Nupc, Nupg, And Tsx Encoding Transporting And Pore-Forming Proteins. Binds Cytidine And Adenosine As Effectors. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=308, Percent_Identity=28.2467532467532, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787948, Length=323, Percent_Identity=29.4117647058824, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789068, Length=310, Percent_Identity=29.3548387096774, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790194, Length=299, Percent_Identity=26.4214046822742, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787580, Length=334, Percent_Identity=26.0479041916168, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788474, Length=279, Percent_Identity=27.5985663082437, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789202, Length=275, Percent_Identity=26.1818181818182, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI48994940, Length=309, Percent_Identity=24.9190938511327, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787906, Length=120, Percent_Identity=37.5, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786268, Length=329, Percent_Identity=23.4042553191489, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36119; Mature: 35987

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIRDIAKHADVSVTTVSRVLNEHPYVSKEKRTRVHAAMKELGYLRNQQALTLSTGKTQ
CCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
RIVVILPYMDHPYYGFFVNGLAKAALEHDYRLVMWQTEYKLSEERQALDLLKHREVDGAI
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEE
VLSHEMSFKEMETYRAYGPIAVATVGAPETISSIHVDHYASFVSGIRVLQQYGYEEIGII
EEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
LSRSHSPSSLARQQAYFDEVAHAREQWIWTGYLTSEDGIRLAETFLSQKERPRALFFSSD
EECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECC
YVALGFLGEMQRRDIKIPQEVAMLGFDGHPIGHAFGLSTMLSPNEEIGRRLFETTLAEMN
CEEEHHHHHHHHCCCCCCHHHHEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GAQPETHGMTVSYQVGTTL
CCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
ANIRDIAKHADVSVTTVSRVLNEHPYVSKEKRTRVHAAMKELGYLRNQQALTLSTGKTQ
CCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCE
RIVVILPYMDHPYYGFFVNGLAKAALEHDYRLVMWQTEYKLSEERQALDLLKHREVDGAI
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEE
VLSHEMSFKEMETYRAYGPIAVATVGAPETISSIHVDHYASFVSGIRVLQQYGYEEIGII
EEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
LSRSHSPSSLARQQAYFDEVAHAREQWIWTGYLTSEDGIRLAETFLSQKERPRALFFSSD
EECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECC
YVALGFLGEMQRRDIKIPQEVAMLGFDGHPIGHAFGLSTMLSPNEEIGRRLFETTLAEMN
CEEEHHHHHHHHCCCCCCHHHHEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GAQPETHGMTVSYQVGTTL
CCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]