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The map label for this gene is malL [H]

Identifier: 229917664

GI number: 229917664

Start: 1901790

End: 1903439

Strand: Direct

Name: malL [H]

Synonym: EAT1b_1941

Alternate gene names: 229917664

Gene position: 1901790-1903439 (Clockwise)

Preceding gene: 229917659

Following gene: 229917665

Centisome position: 63.4

GC content: 48.73

Gene sequence:

>1650_bases
ATGAAACAATGGTGGAAAGAAGCGGTCGTATATCAAATTTATCCACGTAGCTTCAATGACTCAAACGGTGATGGGATTGG
CGACATTCAAGGAATCACGGAGAAGATGTCTTATTTGGCAGAACTCGGGATCGACGTCATCTGGCTCTCGCCGGTATACG
ATTCACCGAACGACGACAATGGATACGATATTCGTGATTACCGTGCCATCATGGACGAGTTTGGTACGATGGATGACTTC
GATGCGATGCTTGAAGAAGCACACCGTCACGGGATTAAAATCATGATGGACCTCGTCGTCAATCACTCTTCGGACGAACA
CCAATGGTTCATGGAGTCACGTTCTTCAAAAGACAGCCCATATCGTGACTATTACATTTGGAAAAAAGGGAAAGATGGTC
AACCTCCGACGAACTGGGGGGCTTTCTTCGGCGGCAGCGCTTGGCAGTATGATGAGGCGAGTGATGAGTACTACCTCCAC
CTCTTCAGTAAGAAACAACCGGATTTGAACTGGGAAAGCGAGACGCTTCGTCGTGAAGTGTACGACCTCATGACATATTG
GCTCGATAAAGGGGTCGACGGGTTCCGGATGGACGTCATCAATATGATTTCAAAAGACCCGAGCTATCCAGACGGTCAAA
CGCAAGGAACGGGGTATGGAGACGGGACACCATTCTTCTTTAACGGACCACGCATCCATGAATTCATGCAGGAGATGAAT
CGTGAAGTCTTATCGAAATATGACACGATCACGGTCGGGGAGATGCCAGGGGTCAGTGTAGAGGAAGCAAAACTTTATAC
GGGTGAAGACCGAAACGAACTGAACATGGTCTTTCATTTTGAACATGTGGATGTCGGGAACGGGAGCTTCGGGAAGTGGA
ATCCGACAGACTGGAAGTTGACTGAGCTGAAGACGATTTTTTCGCGTTGGCAAGAAGGGCTCGAAGAGGAAGGATGGAAC
AGCCTGTACTGGAGTAATCATGACCAGCCCCGTGCCATCTCGCGCTTCGGGAACGATTCGCCTGAATATCGCGTCCGTTC
CGGGAAGATGCTTGCGACACTTCTTCATCTATTGAAAGGGACACCTTACATTTATCAAGGGGAAGAGTTCGGCATGACGA
ACGTCGCGTTTGATTCAATCGATCAGTACCGAGATATTGAGACGTTGAACGCCTACCGTGATTACACATCAAAAGGGTTG
TTAACGCACGACGAGATTTTCCGTGGCATCCATGAGCGAGGACGTGACAATTCACGCACACCGGTACAGTGGTCAGACGA
AGCACATGGTGGATTTACGACAGGGACGCCGTGGATCGAGGTCAATCCGAACTATGTCGATATCAATGCGGAAGCGGCAC
AGAAAGACCCGAATTCGCTCTTCCATTACTACCGTCAATTGATTGCGCTCCGTAAAGCCAATCCGCTCGTTGTCTATGGA
AAGTATGAGCTGTTATTACCGGAAGATGAGGCAATCTATGCGTTCACACGTTCGTTCGAAGGAGAGGCATGGCTCGTGCT
TTGTAACTTCTCAGGTGACACACAACAACGTGACTTACCATATGACGTAAAAGAACGCGTCATCGGAAACATGGAACCGA
TTGAACCGTTCACCCTTCGTCCTTACGAAGCACAAGTGTATAAACTGTGA

Upstream 100 bases:

>100_bases
AGATTGTACATATCTTAATCATATCATGGATGGTCATGATTCCTTGGAGGCAGTACGATGAAAGCGTTGAAACGGAAATG
AACTTCAAGGAGGACGTAAC

Downstream 100 bases:

>100_bases
CGAAAAGCTCGCCAGACGGCGAGCTTTTTTGAGTGGTCGCGTATCTTCTTCTCACGATTCGGGAATAGTGTAAGTAACGT
CTGACATGAAAAGAGGGAAC

Product: alpha amylase catalytic region

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKQWWKEAVVYQIYPRSFNDSNGDGIGDIQGITEKMSYLAELGIDVIWLSPVYDSPNDDNGYDIRDYRAIMDEFGTMDDF
DAMLEEAHRHGIKIMMDLVVNHSSDEHQWFMESRSSKDSPYRDYYIWKKGKDGQPPTNWGAFFGGSAWQYDEASDEYYLH
LFSKKQPDLNWESETLRREVYDLMTYWLDKGVDGFRMDVINMISKDPSYPDGQTQGTGYGDGTPFFFNGPRIHEFMQEMN
REVLSKYDTITVGEMPGVSVEEAKLYTGEDRNELNMVFHFEHVDVGNGSFGKWNPTDWKLTELKTIFSRWQEGLEEEGWN
SLYWSNHDQPRAISRFGNDSPEYRVRSGKMLATLLHLLKGTPYIYQGEEFGMTNVAFDSIDQYRDIETLNAYRDYTSKGL
LTHDEIFRGIHERGRDNSRTPVQWSDEAHGGFTTGTPWIEVNPNYVDINAEAAQKDPNSLFHYYRQLIALRKANPLVVYG
KYELLLPEDEAIYAFTRSFEGEAWLVLCNFSGDTQQRDLPYDVKERVIGNMEPIEPFTLRPYEAQVYKL

Sequences:

>Translated_549_residues
MKQWWKEAVVYQIYPRSFNDSNGDGIGDIQGITEKMSYLAELGIDVIWLSPVYDSPNDDNGYDIRDYRAIMDEFGTMDDF
DAMLEEAHRHGIKIMMDLVVNHSSDEHQWFMESRSSKDSPYRDYYIWKKGKDGQPPTNWGAFFGGSAWQYDEASDEYYLH
LFSKKQPDLNWESETLRREVYDLMTYWLDKGVDGFRMDVINMISKDPSYPDGQTQGTGYGDGTPFFFNGPRIHEFMQEMN
REVLSKYDTITVGEMPGVSVEEAKLYTGEDRNELNMVFHFEHVDVGNGSFGKWNPTDWKLTELKTIFSRWQEGLEEEGWN
SLYWSNHDQPRAISRFGNDSPEYRVRSGKMLATLLHLLKGTPYIYQGEEFGMTNVAFDSIDQYRDIETLNAYRDYTSKGL
LTHDEIFRGIHERGRDNSRTPVQWSDEAHGGFTTGTPWIEVNPNYVDINAEAAQKDPNSLFHYYRQLIALRKANPLVVYG
KYELLLPEDEAIYAFTRSFEGEAWLVLCNFSGDTQQRDLPYDVKERVIGNMEPIEPFTLRPYEAQVYKL
>Mature_549_residues
MKQWWKEAVVYQIYPRSFNDSNGDGIGDIQGITEKMSYLAELGIDVIWLSPVYDSPNDDNGYDIRDYRAIMDEFGTMDDF
DAMLEEAHRHGIKIMMDLVVNHSSDEHQWFMESRSSKDSPYRDYYIWKKGKDGQPPTNWGAFFGGSAWQYDEASDEYYLH
LFSKKQPDLNWESETLRREVYDLMTYWLDKGVDGFRMDVINMISKDPSYPDGQTQGTGYGDGTPFFFNGPRIHEFMQEMN
REVLSKYDTITVGEMPGVSVEEAKLYTGEDRNELNMVFHFEHVDVGNGSFGKWNPTDWKLTELKTIFSRWQEGLEEEGWN
SLYWSNHDQPRAISRFGNDSPEYRVRSGKMLATLLHLLKGTPYIYQGEEFGMTNVAFDSIDQYRDIETLNAYRDYTSKGL
LTHDEIFRGIHERGRDNSRTPVQWSDEAHGGFTTGTPWIEVNPNYVDINAEAAQKDPNSLFHYYRQLIALRKANPLVVYG
KYELLLPEDEAIYAFTRSFEGEAWLVLCNFSGDTQQRDLPYDVKERVIGNMEPIEPFTLRPYEAQVYKL

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=538, Percent_Identity=29.368029739777, Blast_Score=242, Evalue=8e-64,
Organism=Escherichia coli, GI1790687, Length=554, Percent_Identity=45.1263537906137, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI1786604, Length=192, Percent_Identity=27.6041666666667, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25147709, Length=491, Percent_Identity=24.847250509165, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI32565753, Length=548, Percent_Identity=22.4452554744526, Blast_Score=111, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6321726, Length=576, Percent_Identity=41.3194444444444, Blast_Score=442, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6322245, Length=574, Percent_Identity=42.1602787456446, Blast_Score=437, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6324416, Length=576, Percent_Identity=41.6666666666667, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322241, Length=576, Percent_Identity=41.6666666666667, Blast_Score=431, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322021, Length=576, Percent_Identity=41.6666666666667, Blast_Score=431, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321731, Length=577, Percent_Identity=39.5147313691508, Blast_Score=405, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6319776, Length=577, Percent_Identity=39.3414211438475, Blast_Score=403, Evalue=1e-113,
Organism=Drosophila melanogaster, GI221330053, Length=591, Percent_Identity=35.0253807106599, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI24583747, Length=548, Percent_Identity=35.7664233576642, Blast_Score=295, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24583749, Length=548, Percent_Identity=35.7664233576642, Blast_Score=295, Evalue=7e-80,
Organism=Drosophila melanogaster, GI24583745, Length=542, Percent_Identity=33.7638376383764, Blast_Score=281, Evalue=7e-76,
Organism=Drosophila melanogaster, GI24586593, Length=535, Percent_Identity=35.3271028037383, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24586599, Length=557, Percent_Identity=32.4955116696589, Blast_Score=275, Evalue=8e-74,
Organism=Drosophila melanogaster, GI24586591, Length=506, Percent_Identity=34.3873517786561, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24586589, Length=547, Percent_Identity=32.7239488117002, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24586597, Length=547, Percent_Identity=32.9067641681901, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI45549022, Length=546, Percent_Identity=31.6849816849817, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24586587, Length=510, Percent_Identity=33.7254901960784, Blast_Score=248, Evalue=8e-66,
Organism=Drosophila melanogaster, GI281360393, Length=479, Percent_Identity=31.9415448851775, Blast_Score=200, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 63959; Mature: 63959

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQWWKEAVVYQIYPRSFNDSNGDGIGDIQGITEKMSYLAELGIDVIWLSPVYDSPNDDN
CCCHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
GYDIRDYRAIMDEFGTMDDFDAMLEEAHRHGIKIMMDLVVNHSSDEHQWFMESRSSKDSP
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHCCCCCCC
YRDYYIWKKGKDGQPPTNWGAFFGGSAWQYDEASDEYYLHLFSKKQPDLNWESETLRREV
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
YDLMTYWLDKGVDGFRMDVINMISKDPSYPDGQTQGTGYGDGTPFFFNGPRIHEFMQEMN
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHH
REVLSKYDTITVGEMPGVSVEEAKLYTGEDRNELNMVFHFEHVDVGNGSFGKWNPTDWKL
HHHHHHCCCEEECCCCCCCHHHCEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHH
TELKTIFSRWQEGLEEEGWNSLYWSNHDQPRAISRFGNDSPEYRVRSGKMLATLLHLLKG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCEEECCCHHHHHHHHHHCC
TPYIYQGEEFGMTNVAFDSIDQYRDIETLNAYRDYTSKGLLTHDEIFRGIHERGRDNSRT
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
PVQWSDEAHGGFTTGTPWIEVNPNYVDINAEAAQKDPNSLFHYYRQLIALRKANPLVVYG
CEEECCCCCCCCCCCCCEEEECCCEEEECCHHCCCCHHHHHHHHHHHHHHHCCCCEEEEE
KYELLLPEDEAIYAFTRSFEGEAWLVLCNFSGDTQQRDLPYDVKERVIGNMEPIEPFTLR
EEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCEEC
PYEAQVYKL
CCCCEEECC
>Mature Secondary Structure
MKQWWKEAVVYQIYPRSFNDSNGDGIGDIQGITEKMSYLAELGIDVIWLSPVYDSPNDDN
CCCHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
GYDIRDYRAIMDEFGTMDDFDAMLEEAHRHGIKIMMDLVVNHSSDEHQWFMESRSSKDSP
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHCCCCCCC
YRDYYIWKKGKDGQPPTNWGAFFGGSAWQYDEASDEYYLHLFSKKQPDLNWESETLRREV
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHH
YDLMTYWLDKGVDGFRMDVINMISKDPSYPDGQTQGTGYGDGTPFFFNGPRIHEFMQEMN
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHH
REVLSKYDTITVGEMPGVSVEEAKLYTGEDRNELNMVFHFEHVDVGNGSFGKWNPTDWKL
HHHHHHCCCEEECCCCCCCHHHCEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCHH
TELKTIFSRWQEGLEEEGWNSLYWSNHDQPRAISRFGNDSPEYRVRSGKMLATLLHLLKG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCEEECCCHHHHHHHHHHCC
TPYIYQGEEFGMTNVAFDSIDQYRDIETLNAYRDYTSKGLLTHDEIFRGIHERGRDNSRT
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
PVQWSDEAHGGFTTGTPWIEVNPNYVDINAEAAQKDPNSLFHYYRQLIALRKANPLVVYG
CEEECCCCCCCCCCCCCEEEECCCEEEECCHHCCCCHHHHHHHHHHHHHHHCCCCEEEEE
KYELLLPEDEAIYAFTRSFEGEAWLVLCNFSGDTQQRDLPYDVKERVIGNMEPIEPFTLR
EEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCEEC
PYEAQVYKL
CCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2120057; 8370659; 9193006 [H]