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The map label for this gene is moaE [H]

Identifier: 229917639

GI number: 229917639

Start: 1877208

End: 1877663

Strand: Direct

Name: moaE [H]

Synonym: EAT1b_1915

Alternate gene names: 229917639

Gene position: 1877208-1877663 (Clockwise)

Preceding gene: 229917638

Following gene: 229917640

Centisome position: 62.58

GC content: 53.07

Gene sequence:

>456_bases
ATGAAATGGTATCAAGTGAATGAACATCCGCTCGAACCGATGGCGCTTTACGAAACGGTCCGGCATCGAAACGTCGGGGC
GGTCGTGCTGTTTATCGGGACGGTGCGAGAAATGACGGGTTCCAAACAGACTGAGCTCTTGGAGTATGAATCATACGTAC
CGATGGCCGAGAAGATGCTCGAACAAATCGCGAAAGAAGTGGCGGAACGTTGGCCTGGTGCGTTGACGGCGATCCATCAC
CGGATTGGACGACTCGATATCATGGAAGAAGCGGTCGTCATCGCGACGAGTTCTTCCCATCGCGCCGACGCATACGAGGC
GAATCGTTACGCCATCGAACGGATTAAAGAAATTGTCCCAATTTGGAAACGGGAGCATTGGACCGACGGCACGAAATGGA
TGGGTGATCAAAAAGAACAACACCCAGGACGCCCGGAAGGAGTGACGTACACATGA

Upstream 100 bases:

>100_bases
GGGCATGAACAACCGGTCGATGTGACGAACGTGATCGCGCGCGGAGATTCCGTGGCAGACAAGGACCGGTTGATGCGTTT
AGTGGAAAGGTGGATGGAGA

Downstream 100 bases:

>100_bases
TTGAGGTATTATGTTTTGCCCACGTGGCAGAAGAGTTGGCGGTCCGGTCCTATACCGTTTCGGCTCCACAAACAATCGCC
GCCTTGCGAGCGGATTTGGC

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKWYQVNEHPLEPMALYETVRHRNVGAVVLFIGTVREMTGSKQTELLEYESYVPMAEKMLEQIAKEVAERWPGALTAIHH
RIGRLDIMEEAVVIATSSSHRADAYEANRYAIERIKEIVPIWKREHWTDGTKWMGDQKEQHPGRPEGVTYT

Sequences:

>Translated_151_residues
MKWYQVNEHPLEPMALYETVRHRNVGAVVLFIGTVREMTGSKQTELLEYESYVPMAEKMLEQIAKEVAERWPGALTAIHH
RIGRLDIMEEAVVIATSSSHRADAYEANRYAIERIKEIVPIWKREHWTDGTKWMGDQKEQHPGRPEGVTYT
>Mature_151_residues
MKWYQVNEHPLEPMALYETVRHRNVGAVVLFIGTVREMTGSKQTELLEYESYVPMAEKMLEQIAKEVAERWPGALTAIHH
RIGRLDIMEEAVVIATSSSHRADAYEANRYAIERIKEIVPIWKREHWTDGTKWMGDQKEQHPGRPEGVTYT

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=40.7079646017699, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI1787003, Length=109, Percent_Identity=37.6146788990826, Blast_Score=80, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=127, Percent_Identity=33.0708661417323, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356259, Length=149, Percent_Identity=31.5436241610738, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17547; Mature: 17547

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWYQVNEHPLEPMALYETVRHRNVGAVVLFIGTVREMTGSKQTELLEYESYVPMAEKML
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHH
EQIAKEVAERWPGALTAIHHRIGRLDIMEEAVVIATSSSHRADAYEANRYAIERIKEIVP
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
IWKREHWTDGTKWMGDQKEQHPGRPEGVTYT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKWYQVNEHPLEPMALYETVRHRNVGAVVLFIGTVREMTGSKQTELLEYESYVPMAEKML
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHH
EQIAKEVAERWPGALTAIHHRIGRLDIMEEAVVIATSSSHRADAYEANRYAIERIKEIVP
HHHHHHHHHHCCHHHHHHHHHHCCHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
IWKREHWTDGTKWMGDQKEQHPGRPEGVTYT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]