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The map label for this gene is gmuR [H]

Identifier: 229917612

GI number: 229917612

Start: 1853973

End: 1854701

Strand: Direct

Name: gmuR [H]

Synonym: EAT1b_1887

Alternate gene names: 229917612

Gene position: 1853973-1854701 (Clockwise)

Preceding gene: 229917611

Following gene: 229917613

Centisome position: 61.8

GC content: 41.7

Gene sequence:

>729_bases
ATGTCTACTAAGAAAAAACCAAAATATGAAACCATTGCTGATGAAATTCGTAAAAGAATTATTGAACACGTTTATCCGCT
AGAACATGCATTACCTGATGAAATCCATTTGGCCCAAGAGTTTGAGGTGAGCCGAATGACGATGAAACGTGCGCTTGAGA
TTCTCGTCATGGAAGGGCTGATTTATCGTAAACGTGGCAAAGGAACATTCATTTTACAGTCGAGCTTCCAAAAAGATCGC
ATCAACGTGATTAGCAAAGAAACGAGAGGGCTGACTCAAGTAATCGGAGATCGCTCGTTACGAAGTGAGGTCCTCAATTT
TGAGGTGAAGTTTCCGAGTCAGGAAGTCGCCAATCATCTCATGATTGAGCTGACAGAACCAGTCTATGAAATACGTCGTG
TGCGTTACGTAGACGAGGAGCCATATGTCATTGAATTGACGTACATGGTTGCTAACCTCATTACGGGAATCACACGTGAA
ATTTTAGAAAAGTCCGTGTATGCGTATATTCAAGAAGAGCTGGGTTATACGATTACAAGCTCGCATAAAGTGATACGAGC
AGATAAACCGGATGAGTACGATCAAGCTTACTTGAAGAATGATGTCACTGAACCGATTATCGAAGTCGAGCAAGTTGTCT
ATTTGAGTAACGGGAAACCGTTCGAGTATTCGTTTGCCCGTCACCGATACGATAAATTTGTGTTTTCATCGGTCAATATT
GTGAAGTGA

Upstream 100 bases:

>100_bases
GCGAAAGGTTTCACAGAATAATGAAGCGAACTGACAAAGACTACTCTTTGTCAGTTTTTTTTGATATATTGTACATATAT
GTCTATACATGAGGTGCTAT

Downstream 100 bases:

>100_bases
AAGTCGCCGCGATGGCGACTTTTTCGTAAGGAGGACCCATCGTGGATGTGAGAATTGAACAAGCAGGATATGAGAGTAAC
GAGCCCGTCATTCAAGACAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSTKKKPKYETIADEIRKRIIEHVYPLEHALPDEIHLAQEFEVSRMTMKRALEILVMEGLIYRKRGKGTFILQSSFQKDR
INVISKETRGLTQVIGDRSLRSEVLNFEVKFPSQEVANHLMIELTEPVYEIRRVRYVDEEPYVIELTYMVANLITGITRE
ILEKSVYAYIQEELGYTITSSHKVIRADKPDEYDQAYLKNDVTEPIIEVEQVVYLSNGKPFEYSFARHRYDKFVFSSVNI
VK

Sequences:

>Translated_242_residues
MSTKKKPKYETIADEIRKRIIEHVYPLEHALPDEIHLAQEFEVSRMTMKRALEILVMEGLIYRKRGKGTFILQSSFQKDR
INVISKETRGLTQVIGDRSLRSEVLNFEVKFPSQEVANHLMIELTEPVYEIRRVRYVDEEPYVIELTYMVANLITGITRE
ILEKSVYAYIQEELGYTITSSHKVIRADKPDEYDQAYLKNDVTEPIIEVEQVVYLSNGKPFEYSFARHRYDKFVFSSVNI
VK
>Mature_241_residues
STKKKPKYETIADEIRKRIIEHVYPLEHALPDEIHLAQEFEVSRMTMKRALEILVMEGLIYRKRGKGTFILQSSFQKDRI
NVISKETRGLTQVIGDRSLRSEVLNFEVKFPSQEVANHLMIELTEPVYEIRRVRYVDEEPYVIELTYMVANLITGITREI
LEKSVYAYIQEELGYTITSSHKVIRADKPDEYDQAYLKNDVTEPIIEVEQVVYLSNGKPFEYSFARHRYDKFVFSSVNIV
K

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=218, Percent_Identity=31.1926605504587, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786950, Length=233, Percent_Identity=32.1888412017167, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788418, Length=246, Percent_Identity=31.3008130081301, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082252, Length=222, Percent_Identity=24.7747747747748, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28435; Mature: 28304

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKKKPKYETIADEIRKRIIEHVYPLEHALPDEIHLAQEFEVSRMTMKRALEILVMEGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYRKRGKGTFILQSSFQKDRINVISKETRGLTQVIGDRSLRSEVLNFEVKFPSQEVANHL
HHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEECCHHHHHHHH
MIELTEPVYEIRRVRYVDEEPYVIELTYMVANLITGITREILEKSVYAYIQEELGYTITS
HHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
SHKVIRADKPDEYDQAYLKNDVTEPIIEVEQVVYLSNGKPFEYSFARHRYDKFVFSSVNI
CCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCC
VK
CC
>Mature Secondary Structure 
STKKKPKYETIADEIRKRIIEHVYPLEHALPDEIHLAQEFEVSRMTMKRALEILVMEGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYRKRGKGTFILQSSFQKDRINVISKETRGLTQVIGDRSLRSEVLNFEVKFPSQEVANHL
HHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEECCHHHHHHHH
MIELTEPVYEIRRVRYVDEEPYVIELTYMVANLITGITREILEKSVYAYIQEELGYTITS
HHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
SHKVIRADKPDEYDQAYLKNDVTEPIIEVEQVVYLSNGKPFEYSFARHRYDKFVFSSVNI
CCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]