Click here to switch to the map view.

The map label for this gene is gmuC [H]

Identifier: 229917610

GI number: 229917610

Start: 1851106

End: 1852431

Strand: Direct

Name: gmuC [H]

Synonym: EAT1b_1885

Alternate gene names: 229917610

Gene position: 1851106-1852431 (Clockwise)

Preceding gene: 229917609

Following gene: 229917611

Centisome position: 61.71

GC content: 45.25

Gene sequence:

>1326_bases
ATGTCACAGGACAATAAGATGTTCAACATGATCAGTAAACTGCTCATGCCGATGGCGACCTATTTAAACAACAGTCGCTA
TTTACAAGTATTGCGAGATGCATTCATGCTCGCTTTCCCGATTACCATGTTTGGGTCAATCATCGTCGTCATTGCAAACC
TGCCGTTCCTCGACCGTTTCATGTCCGAGAGTACACTCAGTGTATTTAAAACATCACTCGGAAATGCACCATCTGCAACG
ATGGGGATTATGTCTATCTTTGTCGTCTTCGGTATCGGGTATTATCTATCGAAAAGTTATCAAGTCGAGGCTGTCTTCGG
AGGAGCGATCTCGCTCGTGTCTTTCCTTCTCTTAACGCCTTTCTTGATTGAAGTGGACGGTATGTCAGAGGCAGTCGGGA
ATGTCCTTCCGTTGGATCGCCTTGGAGCGAAAGGGATGTTCCTTGCGATGATTACCGGATTCCTGTCCGGTGAGATTTAT
CGATTTGTCGTTCAAAAGAACTGGACGATTAAGATGCCGGATGGAGTACCGCCAGCTGTTGCGAAATCATTCTCAGCACT
TGTTCCTGCATTATTAACCTTGACTGTATTTTTAACATTCAACATCATCGTGACGAACTTATTCAATACGAATCTTCATG
ACGTCATTTTCAACGTCGTTCAGCAACCGCTTGTGACATTAGGGAATGGTCTCATTCCAACGTTGATCGCAATCTTCTTC
GTTCAGCTATTTTGGTTCTTCGGACTCCACGGTCAGGTCATCGTCAACTCGGTGATGGACCCGATTTGGAACACATTATC
TGTGGAAAACTTGACGGCTTATACCTCGACTGGAGATGTTCCGAACATTATCAGTAAACAGTTCATCGAAATTTACACGG
TAGGGCTTGGTGGTTCCGGATCTACACTTGCTGTCGTCGTGGCCATCTTGTTGTTCTTGAAATCGAAACAGTTGAAACAA
ATCGGGAAACTATCCCTCGGACCTGGACTATTTAACGTAAACGAGCCGGTCATCTTCGGACTTCCGATTGTTATGAACCC
GCTCATCATGATTCCTTGGATTGTCGCACCGCTCGTGACGGTAACGGTCACATATTTCGCGATGTCGACAGGCTTAGTCC
CACCACCAACGGGTGTCGCTGTTCCATGGACTGTTCCAATGTTCTTGAGTGGTATCATGGCGACGAACTCGCTTGCCGGA
GGTCTTCTTCAAATCGTGAACTTCTTCATTATTTTGGCGATTTGGTTCCCGTTCTTGAAATTTATCGACCGCATGAACTT
GAAAAAAGAGTTAGAAGAATCAACAGATAAACAAGAAGCAGTGTAA

Upstream 100 bases:

>100_bases
ACCATTTAATGTCTACGCAAACGATGCTTGATTTGACAGCGGGTTTGGTCGAAATGGTCGAACAAAAGATTGTAAATCCT
AATCAAGAAGGGTGAATCAT

Downstream 100 bases:

>100_bases
ACAAATAGAGAAAATAGAAATAAGGGAGAGATAAAAGATGACGAACCCGACACAAACACGAATGAAAGAGCAAAAGACCT
ATCAATTTCCGACAGACTTT

Product: PTS system, cellobiose-specific IIC subunit

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Glucomannan utilization protein C; PTS system oligo-beta-mannoside-specific EIIC component [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSQDNKMFNMISKLLMPMATYLNNSRYLQVLRDAFMLAFPITMFGSIIVVIANLPFLDRFMSESTLSVFKTSLGNAPSAT
MGIMSIFVVFGIGYYLSKSYQVEAVFGGAISLVSFLLLTPFLIEVDGMSEAVGNVLPLDRLGAKGMFLAMITGFLSGEIY
RFVVQKNWTIKMPDGVPPAVAKSFSALVPALLTLTVFLTFNIIVTNLFNTNLHDVIFNVVQQPLVTLGNGLIPTLIAIFF
VQLFWFFGLHGQVIVNSVMDPIWNTLSVENLTAYTSTGDVPNIISKQFIEIYTVGLGGSGSTLAVVVAILLFLKSKQLKQ
IGKLSLGPGLFNVNEPVIFGLPIVMNPLIMIPWIVAPLVTVTVTYFAMSTGLVPPPTGVAVPWTVPMFLSGIMATNSLAG
GLLQIVNFFIILAIWFPFLKFIDRMNLKKELEESTDKQEAV

Sequences:

>Translated_441_residues
MSQDNKMFNMISKLLMPMATYLNNSRYLQVLRDAFMLAFPITMFGSIIVVIANLPFLDRFMSESTLSVFKTSLGNAPSAT
MGIMSIFVVFGIGYYLSKSYQVEAVFGGAISLVSFLLLTPFLIEVDGMSEAVGNVLPLDRLGAKGMFLAMITGFLSGEIY
RFVVQKNWTIKMPDGVPPAVAKSFSALVPALLTLTVFLTFNIIVTNLFNTNLHDVIFNVVQQPLVTLGNGLIPTLIAIFF
VQLFWFFGLHGQVIVNSVMDPIWNTLSVENLTAYTSTGDVPNIISKQFIEIYTVGLGGSGSTLAVVVAILLFLKSKQLKQ
IGKLSLGPGLFNVNEPVIFGLPIVMNPLIMIPWIVAPLVTVTVTYFAMSTGLVPPPTGVAVPWTVPMFLSGIMATNSLAG
GLLQIVNFFIILAIWFPFLKFIDRMNLKKELEESTDKQEAV
>Mature_440_residues
SQDNKMFNMISKLLMPMATYLNNSRYLQVLRDAFMLAFPITMFGSIIVVIANLPFLDRFMSESTLSVFKTSLGNAPSATM
GIMSIFVVFGIGYYLSKSYQVEAVFGGAISLVSFLLLTPFLIEVDGMSEAVGNVLPLDRLGAKGMFLAMITGFLSGEIYR
FVVQKNWTIKMPDGVPPAVAKSFSALVPALLTLTVFLTFNIIVTNLFNTNLHDVIFNVVQQPLVTLGNGLIPTLIAIFFV
QLFWFFGLHGQVIVNSVMDPIWNTLSVENLTAYTSTGDVPNIISKQFIEIYTVGLGGSGSTLAVVVAILLFLKSKQLKQI
GKLSLGPGLFNVNEPVIFGLPIVMNPLIMIPWIVAPLVTVTVTYFAMSTGLVPPPTGVAVPWTVPMFLSGIMATNSLAGG
LLQIVNFFIILAIWFPFLKFIDRMNLKKELEESTDKQEAV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=453, Percent_Identity=32.2295805739514, Blast_Score=225, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48321; Mature: 48190

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SQDNKMFNMISKLLMPMATYLNNSRYLQVLRDAFMLAFPITMFGSIIVVIANLPFLDRF
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
MSESTLSVFKTSLGNAPSATMGIMSIFVVFGIGYYLSKSYQVEAVFGGAISLVSFLLLTP
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHH
FLIEVDGMSEAVGNVLPLDRLGAKGMFLAMITGFLSGEIYRFVVQKNWTIKMPDGVPPAV
HHEEECCHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCEEECCCCCCHHH
AKSFSALVPALLTLTVFLTFNIIVTNLFNTNLHDVIFNVVQQPLVTLGNGLIPTLIAIFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VQLFWFFGLHGQVIVNSVMDPIWNTLSVENLTAYTSTGDVPNIISKQFIEIYTVGLGGSG
HHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCEEECCCCCCHHHHHHHHHHHEEEECCCCC
STLAVVVAILLFLKSKQLKQIGKLSLGPGLFNVNEPVIFGLPIVMNPLIMIPWIVAPLVT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
VTVTYFAMSTGLVPPPTGVAVPWTVPMFLSGIMATNSLAGGLLQIVNFFIILAIWFPFLK
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIDRMNLKKELEESTDKQEAV
HHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]