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The map label for this gene is htpX [H]

Identifier: 229917592

GI number: 229917592

Start: 1833509

End: 1834393

Strand: Direct

Name: htpX [H]

Synonym: EAT1b_1867

Alternate gene names: 229917592

Gene position: 1833509-1834393 (Clockwise)

Preceding gene: 229917591

Following gene: 229917593

Centisome position: 61.12

GC content: 51.98

Gene sequence:

>885_bases
ATGCTCCTCTATGAACAGATTCGAAAGAATAAAGTGAAGACGGTCTTCATCGTCACAGGGTTTGTCCTATTCGTCCTTCT
CGTTGGGGCGGCGATTTCCTACGTCACCTACGGGGACGCAGTTCCAGGGTTAATTTTCACACCTATTTTCTCGTTGTTTT
ATGTCGGTATCGTCATCATGTCGAGCACGAACATCGTCATGAAGATGAATCGGGCGCAAGAAGTGACATCGGTGGAAGAA
CACCGCTTTTTATGGCATACGGTCGAAAACATGGCGATGGTCGCGCGAGTGCCGATGCCGCGCATCTTTATCATCAACGA
CCCATCGCCGAACGCATTTGCGACGGGGTTGAAGCCAGAAAAGGCGGCTGTCGCCGTCACGACGGGACTGTTGGATCGAT
TATCGCGAGAAGAAATAGAAGGGGTGATTGCGCACGAGGTCGCGCATATTAAAAATTATGATGTCCGACTCTCGACGGTC
ACGCTCGCACTCGTTTCAGTCATCGCTATCATGAGCGATATCGGGTCGCGCATGCTGTTCTTCAGAAGTATCGGTGGAAG
ACGCGATCAAAACCAGAATCCAATTTTCATGATCATCGGACTCGTCCTGTTGGTATTGGCACCGCTCATCGCCATGCTCA
TCAATATGGCGATTTCCCGGAATCGCGAGTTTCTGGCAGATGCGAGTGGGGCGGAACTGACCCGAAACCCAGATGCGCTC
GCCTCGGCGCTTGAGAAGATTGCCAACGTCGAGACACCCGTCGAGCAAGCGTCGAGTGCCTCGGCACCGCTTTACTTCTC
CGATCCACTTAAGAAGAAGGTGAGTGGTCTATTCTCGACACATCCCGATCCAGTCGAACGCATTTCCCGACTTCGTCAAA
TGTAG

Upstream 100 bases:

>100_bases
CGCTTCCGTCCATCATTTCGAAAAGCGCGATATGCTCGAGGCACGTGCCGAAGAGCGCGAGAACGTTCGCGTTTCGTTTT
GATGAATCGAGGTGGCGCGT

Downstream 100 bases:

>100_bases
TCAGAGCCTGTCCGGTTGCGGCAGGCTCTTTATGTTACACTGAACTGGGAAAATAAGGGGGTGGATGAGTTGAATAAAAA
GATATACATAGGTTTAGGCG

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLLYEQIRKNKVKTVFIVTGFVLFVLLVGAAISYVTYGDAVPGLIFTPIFSLFYVGIVIMSSTNIVMKMNRAQEVTSVEE
HRFLWHTVENMAMVARVPMPRIFIINDPSPNAFATGLKPEKAAVAVTTGLLDRLSREEIEGVIAHEVAHIKNYDVRLSTV
TLALVSVIAIMSDIGSRMLFFRSIGGRRDQNQNPIFMIIGLVLLVLAPLIAMLINMAISRNREFLADASGAELTRNPDAL
ASALEKIANVETPVEQASSASAPLYFSDPLKKKVSGLFSTHPDPVERISRLRQM

Sequences:

>Translated_294_residues
MLLYEQIRKNKVKTVFIVTGFVLFVLLVGAAISYVTYGDAVPGLIFTPIFSLFYVGIVIMSSTNIVMKMNRAQEVTSVEE
HRFLWHTVENMAMVARVPMPRIFIINDPSPNAFATGLKPEKAAVAVTTGLLDRLSREEIEGVIAHEVAHIKNYDVRLSTV
TLALVSVIAIMSDIGSRMLFFRSIGGRRDQNQNPIFMIIGLVLLVLAPLIAMLINMAISRNREFLADASGAELTRNPDAL
ASALEKIANVETPVEQASSASAPLYFSDPLKKKVSGLFSTHPDPVERISRLRQM
>Mature_294_residues
MLLYEQIRKNKVKTVFIVTGFVLFVLLVGAAISYVTYGDAVPGLIFTPIFSLFYVGIVIMSSTNIVMKMNRAQEVTSVEE
HRFLWHTVENMAMVARVPMPRIFIINDPSPNAFATGLKPEKAAVAVTTGLLDRLSREEIEGVIAHEVAHIKNYDVRLSTV
TLALVSVIAIMSDIGSRMLFFRSIGGRRDQNQNPIFMIIGLVLLVLAPLIAMLINMAISRNREFLADASGAELTRNPDAL
ASALEKIANVETPVEQASSASAPLYFSDPLKKKVSGLFSTHPDPVERISRLRQM

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=219, Percent_Identity=36.5296803652968, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 32462; Mature: 32462

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLYEQIRKNKVKTVFIVTGFVLFVLLVGAAISYVTYGDAVPGLIFTPIFSLFYVGIVIM
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SSTNIVMKMNRAQEVTSVEEHRFLWHTVENMAMVARVPMPRIFIINDPSPNAFATGLKPE
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCC
KAAVAVTTGLLDRLSREEIEGVIAHEVAHIKNYDVRLSTVTLALVSVIAIMSDIGSRMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FRSIGGRRDQNQNPIFMIIGLVLLVLAPLIAMLINMAISRNREFLADASGAELTRNPDAL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHH
ASALEKIANVETPVEQASSASAPLYFSDPLKKKVSGLFSTHPDPVERISRLRQM
HHHHHHHHCCCCCHHHHCCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLLYEQIRKNKVKTVFIVTGFVLFVLLVGAAISYVTYGDAVPGLIFTPIFSLFYVGIVIM
CCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SSTNIVMKMNRAQEVTSVEEHRFLWHTVENMAMVARVPMPRIFIINDPSPNAFATGLKPE
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCC
KAAVAVTTGLLDRLSREEIEGVIAHEVAHIKNYDVRLSTVTLALVSVIAIMSDIGSRMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FRSIGGRRDQNQNPIFMIIGLVLLVLAPLIAMLINMAISRNREFLADASGAELTRNPDAL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHH
ASALEKIANVETPVEQASSASAPLYFSDPLKKKVSGLFSTHPDPVERISRLRQM
HHHHHHHHCCCCCHHHHCCCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA