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The map label for this gene is ahpC [H]

Identifier: 229917535

GI number: 229917535

Start: 1775712

End: 1776275

Strand: Reverse

Name: ahpC [H]

Synonym: EAT1b_1810

Alternate gene names: 229917535

Gene position: 1776275-1775712 (Counterclockwise)

Preceding gene: 229917536

Following gene: 229917534

Centisome position: 59.21

GC content: 47.7

Gene sequence:

>564_bases
ATGTCATTAATCGGCAAAGAAGTATTACCATTCAAAGCACAAGCATTCCAAACAGGTGAATTCCTCGAAGTTACAGAGAA
CGACCTCAAAGGTAAATGGAGCGTTGTCTGCTTCTACCCAGCTGACTTCACATTCGTCTGCCCAACTGAACTTGAAGACC
TTCAAAACGAGTACGCTACACTTAAAAACCTAGGTGTAGAAGTATACTCTGTCTCTACAGACACACACTTCACACATAAA
GCTTGGCACGAAACATCTGAGAAAATCGGAAAAATCGAGTACATCATGATCGGTGACCCATCACACGTCATCTCACGCAA
CTTCGACGTCTTGAATGAAGAAGACGGCCTCGCAGACCGTGGTACGTTCATCATAGACCCAGACGGCGTCATCCAAACTG
TCGAAATCAACGCTGGCGGCATCGGCCGTGACGCGAGCACGCTCGTCAACAAAGTCAAAGCAGCACAATACGTACGCAAC
AATCCAGGCGAAGTCTGCCCAGCGAAATGGGAAGAGGGTTCTGAAACACTCCGCCCAAGCCTTGACCTCGTCGGTAAATT
GTAA

Upstream 100 bases:

>100_bases
GCCTTGACAATTCCAGCTCGTTATATGAAGTTAGTATTACATTATAATTATTCTAGTCGAGATAGAAACGCTAGAGTAAA
AAACAAGGAGGACATAACCC

Downstream 100 bases:

>100_bases
GGAGCGATTGCATGTTAGAAGCAGCGATTAAACAACAGCTCGACCAATATCTCCAGCTCATGGAGGGCGATGTCGTCCTC
CGTGTGAGCGCTGGGGAAGA

Product: peroxiredoxin

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; General stress protein 22; Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLIGKEVLPFKAQAFQTGEFLEVTENDLKGKWSVVCFYPADFTFVCPTELEDLQNEYATLKNLGVEVYSVSTDTHFTHK
AWHETSEKIGKIEYIMIGDPSHVISRNFDVLNEEDGLADRGTFIIDPDGVIQTVEINAGGIGRDASTLVNKVKAAQYVRN
NPGEVCPAKWEEGSETLRPSLDLVGKL

Sequences:

>Translated_187_residues
MSLIGKEVLPFKAQAFQTGEFLEVTENDLKGKWSVVCFYPADFTFVCPTELEDLQNEYATLKNLGVEVYSVSTDTHFTHK
AWHETSEKIGKIEYIMIGDPSHVISRNFDVLNEEDGLADRGTFIIDPDGVIQTVEINAGGIGRDASTLVNKVKAAQYVRN
NPGEVCPAKWEEGSETLRPSLDLVGKL
>Mature_186_residues
SLIGKEVLPFKAQAFQTGEFLEVTENDLKGKWSVVCFYPADFTFVCPTELEDLQNEYATLKNLGVEVYSVSTDTHFTHKA
WHETSEKIGKIEYIMIGDPSHVISRNFDVLNEEDGLADRGTFIIDPDGVIQTVEINAGGIGRDASTLVNKVKAAQYVRNN
PGEVCPAKWEEGSETLRPSLDLVGKL

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=43.9306358381503, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=43.9306358381503, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=42.3076923076923, Blast_Score=147, Evalue=4e-36,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=37.3626373626374, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=37.3626373626374, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=37.3626373626374, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI5453549, Length=187, Percent_Identity=38.5026737967914, Blast_Score=130, Evalue=9e-31,
Organism=Homo sapiens, GI33188454, Length=102, Percent_Identity=46.078431372549, Blast_Score=88, Evalue=6e-18,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=65.24064171123, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=40.9836065573771, Blast_Score=146, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=40.9836065573771, Blast_Score=146, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17554494, Length=180, Percent_Identity=39.4444444444444, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323613, Length=185, Percent_Identity=36.2162162162162, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=34.2541436464088, Blast_Score=122, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21357347, Length=184, Percent_Identity=37.5, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=38.4180790960452, Blast_Score=136, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=37.9120879120879, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=37.9120879120879, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=37.2222222222222, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=37.2222222222222, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=24.0506329113924, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20757; Mature: 20625

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIGKEVLPFKAQAFQTGEFLEVTENDLKGKWSVVCFYPADFTFVCPTELEDLQNEYAT
CCCCCCCCCCCCHHHCCCCCEEEECCCCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHH
LKNLGVEVYSVSTDTHFTHKAWHETSEKIGKIEYIMIGDPSHVISRNFDVLNEEDGLADR
HHHCCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCCCCCCCC
GTFIIDPDGVIQTVEINAGGIGRDASTLVNKVKAAQYVRNNPGEVCPAKWEEGSETLRPS
CCEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCC
LDLVGKL
HHHHCCC
>Mature Secondary Structure 
SLIGKEVLPFKAQAFQTGEFLEVTENDLKGKWSVVCFYPADFTFVCPTELEDLQNEYAT
CCCCCCCCCCCHHHCCCCCEEEECCCCCCCEEEEEEEECCCEEEECCHHHHHHHHHHHH
LKNLGVEVYSVSTDTHFTHKAWHETSEKIGKIEYIMIGDPSHVISRNFDVLNEEDGLADR
HHHCCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCCCCCCCCC
GTFIIDPDGVIQTVEINAGGIGRDASTLVNKVKAAQYVRNNPGEVCPAKWEEGSETLRPS
CCEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCC
LDLVGKL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 8180695; 8012595 [H]