Click here to switch to the map view.

The map label for this gene is yyxA [H]

Identifier: 229917482

GI number: 229917482

Start: 1725751

End: 1727010

Strand: Direct

Name: yyxA [H]

Synonym: EAT1b_1757

Alternate gene names: 229917482

Gene position: 1725751-1727010 (Clockwise)

Preceding gene: 229917481

Following gene: 229917483

Centisome position: 57.53

GC content: 53.81

Gene sequence:

>1260_bases
GTGAACGAAGAGAGACACCATGAATATGAACCTCAAGACGTCGAACCTGAAGTACACGAAGCAACAGAAGAGAAATCGAC
GTATCCGTCTCGGAGCGAATGGCGACCGAAGCAAGAGGAGCACGTACGCCATAAGCCGAGACCAAATATAAAACCGTTGT
TACTCGGAGGGGTTGGCGGATTCTTAGGAGCGGCTTTGTTTTTTGTCATCGTGATGCTCTGGGATTCGCCGACCTCTCGT
TTTGTGACGAATGAACTGACGCGGACCGAACAGGCCGTCACCGTCACCGAATCGGACGTCACGACCGCTGTCCTTGGGGC
GAAGACGTCCGTCGTCAGCATCACCAATATCCAGCGTGCGTTCACCTCGGACTCGCAATGGGAGGCGGGTGCCGGATCCG
GTGTCATCTATAAAGTAGAAGGAAACACGGCCTATATCGTCACGAACTTCCACGTCATCGAAGAAGCGGACGAGGTCAAC
ATCGCCTTTTCCGATGGTCAAATCGCATCGGCAACCATTTTAGGCGAAGACCCGCTCAACGACTTGGCTGTCGCCGAGGT
CGAGTTACCGAAAAATATCGATGTGGAGCCGATTGTTCTCGGGGACTCCACTGTTCTCCAAGCTGGCGAGACCGTCATGG
CCATCGGAAATCCGCTCGGTGTCTTCTCAAACTCGGTCACCCGTGGTATCGTCAGTGGTGTCGAGCGGACGGTGCCGGTC
GATACGAACAGCGATGGCTTGATGGATTATAACGCGGAAGTCATCCAAACGGATGCGGCCATCAACCCGGGGAATTCGGG
TGGTGCCCTCATCAACATTCGTGGAGAACTCGTCGGAATCAATTCGATGAAAATCGCCGAGGCGAGCGTAGAAGGGGTCG
GCTTCTCGATTCCGGTGAACGTGGCGCTACCGGTCATTGACATGTTAGAACGCGACGGCAAGGTGACACGAGCACAGCTC
GGGGTCACGATTCAAGAAGTCATTGCGGTACCCGGTAACGTTCGGGAAGAGTACGGCATCTCATTCGACCAAGAAGACGG
TGTCTTCGTCGAAGAAGTGACACCAGGTAGTCCGGCTGAGGAAGCGGGACTACGTATTGGCGATGTCATCACGAAAATCG
GAGACCGGGAGATCAAACGATACGTCGATTTACGAGATGCGCTCTATCGTGATGCAACAGTCGGTGATACGATTACGATT
GAGTATTTACGTCGCGGGGAAGCGAGAGAAACCGAGGCGACATTAACTGAAGCAACATAA

Upstream 100 bases:

>100_bases
ATTGTGCGACACGGACCCGACAATCCCCACTTCACTCGTTTCTTTATAAGGAAACTTGGGAAAAGACAGTTATCACACTG
TCTTGAAGGGGGGACGCGTC

Downstream 100 bases:

>100_bases
AGAAGCGGCGACGCTTCTTTTTTAAGGAGGAAAAACTGTGGAAAAAAAAGTATGCAAGGAACATGTTGAAATCGCTTTAG
ACATCATTGTGGATGAAACA

Product: peptidase S1 and S6 chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNEERHHEYEPQDVEPEVHEATEEKSTYPSRSEWRPKQEEHVRHKPRPNIKPLLLGGVGGFLGAALFFVIVMLWDSPTSR
FVTNELTRTEQAVTVTESDVTTAVLGAKTSVVSITNIQRAFTSDSQWEAGAGSGVIYKVEGNTAYIVTNFHVIEEADEVN
IAFSDGQIASATILGEDPLNDLAVAEVELPKNIDVEPIVLGDSTVLQAGETVMAIGNPLGVFSNSVTRGIVSGVERTVPV
DTNSDGLMDYNAEVIQTDAAINPGNSGGALINIRGELVGINSMKIAEASVEGVGFSIPVNVALPVIDMLERDGKVTRAQL
GVTIQEVIAVPGNVREEYGISFDQEDGVFVEEVTPGSPAEEAGLRIGDVITKIGDREIKRYVDLRDALYRDATVGDTITI
EYLRRGEARETEATLTEAT

Sequences:

>Translated_419_residues
MNEERHHEYEPQDVEPEVHEATEEKSTYPSRSEWRPKQEEHVRHKPRPNIKPLLLGGVGGFLGAALFFVIVMLWDSPTSR
FVTNELTRTEQAVTVTESDVTTAVLGAKTSVVSITNIQRAFTSDSQWEAGAGSGVIYKVEGNTAYIVTNFHVIEEADEVN
IAFSDGQIASATILGEDPLNDLAVAEVELPKNIDVEPIVLGDSTVLQAGETVMAIGNPLGVFSNSVTRGIVSGVERTVPV
DTNSDGLMDYNAEVIQTDAAINPGNSGGALINIRGELVGINSMKIAEASVEGVGFSIPVNVALPVIDMLERDGKVTRAQL
GVTIQEVIAVPGNVREEYGISFDQEDGVFVEEVTPGSPAEEAGLRIGDVITKIGDREIKRYVDLRDALYRDATVGDTITI
EYLRRGEARETEATLTEAT
>Mature_419_residues
MNEERHHEYEPQDVEPEVHEATEEKSTYPSRSEWRPKQEEHVRHKPRPNIKPLLLGGVGGFLGAALFFVIVMLWDSPTSR
FVTNELTRTEQAVTVTESDVTTAVLGAKTSVVSITNIQRAFTSDSQWEAGAGSGVIYKVEGNTAYIVTNFHVIEEADEVN
IAFSDGQIASATILGEDPLNDLAVAEVELPKNIDVEPIVLGDSTVLQAGETVMAIGNPLGVFSNSVTRGIVSGVERTVPV
DTNSDGLMDYNAEVIQTDAAINPGNSGGALINIRGELVGINSMKIAEASVEGVGFSIPVNVALPVIDMLERDGKVTRAQL
GVTIQEVIAVPGNVREEYGISFDQEDGVFVEEVTPGSPAEEAGLRIGDVITKIGDREIKRYVDLRDALYRDATVGDTITI
EYLRRGEARETEATLTEAT

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI7019477, Length=290, Percent_Identity=34.1379310344828, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI4506141, Length=291, Percent_Identity=30.9278350515464, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI22129776, Length=277, Percent_Identity=31.7689530685921, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI24308541, Length=270, Percent_Identity=32.2222222222222, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1786356, Length=290, Percent_Identity=37.2413793103448, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789629, Length=289, Percent_Identity=36.3321799307958, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1789630, Length=311, Percent_Identity=34.4051446945338, Blast_Score=155, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24646839, Length=290, Percent_Identity=32.7586206896552, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 45278; Mature: 45278

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEERHHEYEPQDVEPEVHEATEEKSTYPSRSEWRPKQEEHVRHKPRPNIKPLLLGGVGG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEECHHH
FLGAALFFVIVMLWDSPTSRFVTNELTRTEQAVTVTESDVTTAVLGAKTSVVSITNIQRA
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCEEEEEEHHHHH
FTSDSQWEAGAGSGVIYKVEGNTAYIVTNFHVIEEADEVNIAFSDGQIASATILGEDPLN
HCCCCCCCCCCCCCEEEEEECCEEEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCC
DLAVAEVELPKNIDVEPIVLGDSTVLQAGETVMAIGNPLGVFSNSVTRGIVSGVERTVPV
CEEEEEEECCCCCCCCEEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHEECC
DTNSDGLMDYNAEVIQTDAAINPGNSGGALINIRGELVGINSMKIAEASVEGVGFSIPVN
CCCCCCCEECCCEEEEECCCCCCCCCCCEEEEEECEEEECCCEEEEHHHHCCCCEEEEHH
VALPVIDMLERDGKVTRAQLGVTIQEVIAVPGNVREEYGISFDQEDGVFVEEVTPGSPAE
HHHHHHHHHHCCCCEEEHHHCCCHHHHHCCCCCCHHHHCCCCCCCCCEEEEECCCCCCHH
EAGLRIGDVITKIGDREIKRYVDLRDALYRDATVGDTITIEYLRRGEARETEATLTEAT
HHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCEEECCC
>Mature Secondary Structure
MNEERHHEYEPQDVEPEVHEATEEKSTYPSRSEWRPKQEEHVRHKPRPNIKPLLLGGVGG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEECHHH
FLGAALFFVIVMLWDSPTSRFVTNELTRTEQAVTVTESDVTTAVLGAKTSVVSITNIQRA
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEEEECCCCEEEEEEHHHHH
FTSDSQWEAGAGSGVIYKVEGNTAYIVTNFHVIEEADEVNIAFSDGQIASATILGEDPLN
HCCCCCCCCCCCCCEEEEEECCEEEEEEEEEEEECCCCEEEEECCCCEEEEEEECCCCCC
DLAVAEVELPKNIDVEPIVLGDSTVLQAGETVMAIGNPLGVFSNSVTRGIVSGVERTVPV
CEEEEEEECCCCCCCCEEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHEECC
DTNSDGLMDYNAEVIQTDAAINPGNSGGALINIRGELVGINSMKIAEASVEGVGFSIPVN
CCCCCCCEECCCEEEEECCCCCCCCCCCEEEEEECEEEECCCEEEEHHHHCCCCEEEEHH
VALPVIDMLERDGKVTRAQLGVTIQEVIAVPGNVREEYGISFDQEDGVFVEEVTPGSPAE
HHHHHHHHHHCCCCEEEHHHCCCHHHHHCCCCCCHHHHCCCCCCCCCEEEEECCCCCCHH
EAGLRIGDVITKIGDREIKRYVDLRDALYRDATVGDTITIEYLRRGEARETEATLTEAT
HHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]