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The map label for this gene is dnaC [H]

Identifier: 229917475

GI number: 229917475

Start: 1717225

End: 1718577

Strand: Direct

Name: dnaC [H]

Synonym: EAT1b_1750

Alternate gene names: 229917475

Gene position: 1717225-1718577 (Clockwise)

Preceding gene: 229917474

Following gene: 229917476

Centisome position: 57.24

GC content: 53.88

Gene sequence:

>1353_bases
ATGAGTGATGCGATTCAAGTCAATACACCACCGCATAGCGTGGAAGCGGAGCAAGCCGTCTTAGGGGCGATCATCCTCGA
TTCGGATCGGTTGATTACGGCCTCAGAGCGGGTCGACCCGGACGACTTTTATCGTGTCAGCCACCAGCGCATCTTTGAAG
CGATGCTAAAAATCAATGACCGAGGTGAGCTCGTCGACTTGGTCACGCTCAGTTCCGAGTTGCAGGCGCAAGGGATTTTA
GACGAGATCGGGGGCCTCAACTATTTGGCGGAGGTCGCGGAATCCGTTCCCGCCATCGGGAACATCGGCTATTACTTGAA
CGTCGTCGACCAAAAAGCGGCACTCCGTCGTCTGATTCGAACAGCGACGAACATCGTCTCGGATGGTTATGAGCGTCAGG
ACGAGGTCGATTCTGTCCTCTCGGACGCGGAGCGGAACATTCTAAAAGTATCGCAACGAAAAGGGCAATCGAGCTTCCAC
CCGATTGGTTCTGTCTTATCCGATGCGTACTCGACGATTGAAAAGCTGCATCAGTCGAGCGGTGAGATCACGGGGATTGC
GACCGGCTTCACGGATTTGGATAAGATGACAGCCGGTTTCCAACGAAACGATTTGATTATCGTGGCCGCCCGTCCATCTG
TCGGGAAGACCGCGTTCGCCTTGAACATCTCGCAAAACGTCGCGGTCCGTACAGGTGAGAACGTCGCCATCTTCAGTTTG
GAGATGGGTGCCGAGCAACTCGTCATGCGTATGTTGTGTGCGGAAGGGAACATCGATGCCCAGCGCCTCCGGACCGGTCG
TCTTGAAGCGGAAGACTGGGGTCGTCTCTCTCTCGCGATGTCGTCGCTCTCACAGGCAGGCATCTACATTGACGATACAC
CGGGTCTTCGGGTCAACGAAATCCGAGCCAAATGTCGCCGATTGAAGCAGGAACATGGTCTCGGGATGATCATGATTGAC
TACTTGCAGCTCATCGTCGGGAACGGGAAACCGGGCGAGAACCGCCAACAAGAAGTATCGGAAATCTCACGTACGCTCAA
AGCGATCGCACGGGAACTACAAGTACCGGTCATCGCCTTGTCTCAGCTCTCACGTGGCGTAGAGAGTCGTCAAGACAAGC
GACCGATGATGTCGGATATCCGTGAATCGGGAGCAATCGAGCAGGATGCCGATATCGTCGCCTTCCTCTACCGTGATGAC
TATTACGATAAAGAGAGTGAAGACGCCAATACGATTGAAATCATCATTGCGAAACAACGTAACGGTCCGACCGGTACGGT
CAAGCTCTCCTTCAGGAAAGAGTACAACAAGTTCGTCAATATGGAGACGCAAGCCTTCGCACCACCGATGTAA

Upstream 100 bases:

>100_bases
AGGCGCTCGGTTTCACGAAAGTGCCAGTGAAGTTGCACCATGACGTCGTCGCGACGTTGAATGTACATGTACAAGAAGCT
TGAAGGTGAGGTAGAGACGG

Downstream 100 bases:

>100_bases
CGTCGGTGGTGTCTTTTTTATATAGGGTTTGGTTAAAATGACGAACGAATAGTTACATCTTATATAAAACGTTCGGTATT
CAATTGACTTTCTCGCTTTT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSDAIQVNTPPHSVEAEQAVLGAIILDSDRLITASERVDPDDFYRVSHQRIFEAMLKINDRGELVDLVTLSSELQAQGIL
DEIGGLNYLAEVAESVPAIGNIGYYLNVVDQKAALRRLIRTATNIVSDGYERQDEVDSVLSDAERNILKVSQRKGQSSFH
PIGSVLSDAYSTIEKLHQSSGEITGIATGFTDLDKMTAGFQRNDLIIVAARPSVGKTAFALNISQNVAVRTGENVAIFSL
EMGAEQLVMRMLCAEGNIDAQRLRTGRLEAEDWGRLSLAMSSLSQAGIYIDDTPGLRVNEIRAKCRRLKQEHGLGMIMID
YLQLIVGNGKPGENRQQEVSEISRTLKAIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGAIEQDADIVAFLYRDD
YYDKESEDANTIEIIIAKQRNGPTGTVKLSFRKEYNKFVNMETQAFAPPM

Sequences:

>Translated_450_residues
MSDAIQVNTPPHSVEAEQAVLGAIILDSDRLITASERVDPDDFYRVSHQRIFEAMLKINDRGELVDLVTLSSELQAQGIL
DEIGGLNYLAEVAESVPAIGNIGYYLNVVDQKAALRRLIRTATNIVSDGYERQDEVDSVLSDAERNILKVSQRKGQSSFH
PIGSVLSDAYSTIEKLHQSSGEITGIATGFTDLDKMTAGFQRNDLIIVAARPSVGKTAFALNISQNVAVRTGENVAIFSL
EMGAEQLVMRMLCAEGNIDAQRLRTGRLEAEDWGRLSLAMSSLSQAGIYIDDTPGLRVNEIRAKCRRLKQEHGLGMIMID
YLQLIVGNGKPGENRQQEVSEISRTLKAIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGAIEQDADIVAFLYRDD
YYDKESEDANTIEIIIAKQRNGPTGTVKLSFRKEYNKFVNMETQAFAPPM
>Mature_449_residues
SDAIQVNTPPHSVEAEQAVLGAIILDSDRLITASERVDPDDFYRVSHQRIFEAMLKINDRGELVDLVTLSSELQAQGILD
EIGGLNYLAEVAESVPAIGNIGYYLNVVDQKAALRRLIRTATNIVSDGYERQDEVDSVLSDAERNILKVSQRKGQSSFHP
IGSVLSDAYSTIEKLHQSSGEITGIATGFTDLDKMTAGFQRNDLIIVAARPSVGKTAFALNISQNVAVRTGENVAIFSLE
MGAEQLVMRMLCAEGNIDAQRLRTGRLEAEDWGRLSLAMSSLSQAGIYIDDTPGLRVNEIRAKCRRLKQEHGLGMIMIDY
LQLIVGNGKPGENRQQEVSEISRTLKAIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGAIEQDADIVAFLYRDDY
YDKESEDANTIEIIIAKQRNGPTGTVKLSFRKEYNKFVNMETQAFAPPM

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=440, Percent_Identity=46.5909090909091, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49784; Mature: 49653

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAIQVNTPPHSVEAEQAVLGAIILDSDRLITASERVDPDDFYRVSHQRIFEAMLKIND
CCCCEECCCCCCCCCHHHHHHEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
RGELVDLVTLSSELQAQGILDEIGGLNYLAEVAESVPAIGNIGYYLNVVDQKAALRRLIR
CCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHH
TATNIVSDGYERQDEVDSVLSDAERNILKVSQRKGQSSFHPIGSVLSDAYSTIEKLHQSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
GEITGIATGFTDLDKMTAGFQRNDLIIVAARPSVGKTAFALNISQNVAVRTGENVAIFSL
CCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEECCCEEEEEE
EMGAEQLVMRMLCAEGNIDAQRLRTGRLEAEDWGRLSLAMSSLSQAGIYIDDTPGLRVNE
CCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHH
IRAKCRRLKQEHGLGMIMIDYLQLIVGNGKPGENRQQEVSEISRTLKAIARELQVPVIAL
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
SQLSRGVESRQDKRPMMSDIRESGAIEQDADIVAFLYRDDYYDKESEDANTIEIIIAKQR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECC
NGPTGTVKLSFRKEYNKFVNMETQAFAPPM
CCCCEEEEEEEHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure 
SDAIQVNTPPHSVEAEQAVLGAIILDSDRLITASERVDPDDFYRVSHQRIFEAMLKIND
CCCEECCCCCCCCCHHHHHHEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCC
RGELVDLVTLSSELQAQGILDEIGGLNYLAEVAESVPAIGNIGYYLNVVDQKAALRRLIR
CCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHH
TATNIVSDGYERQDEVDSVLSDAERNILKVSQRKGQSSFHPIGSVLSDAYSTIEKLHQSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
GEITGIATGFTDLDKMTAGFQRNDLIIVAARPSVGKTAFALNISQNVAVRTGENVAIFSL
CCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEECCCEEEEEE
EMGAEQLVMRMLCAEGNIDAQRLRTGRLEAEDWGRLSLAMSSLSQAGIYIDDTPGLRVNE
CCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHH
IRAKCRRLKQEHGLGMIMIDYLQLIVGNGKPGENRQQEVSEISRTLKAIARELQVPVIAL
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
SQLSRGVESRQDKRPMMSDIRESGAIEQDADIVAFLYRDDYYDKESEDANTIEIIIAKQR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEECC
NGPTGTVKLSFRKEYNKFVNMETQAFAPPM
CCCCEEEEEEEHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]