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The map label for this gene is ykuT [H]

Identifier: 229917467

GI number: 229917467

Start: 1710996

End: 1711937

Strand: Direct

Name: ykuT [H]

Synonym: EAT1b_1742

Alternate gene names: 229917467

Gene position: 1710996-1711937 (Clockwise)

Preceding gene: 229917465

Following gene: 229917468

Centisome position: 57.04

GC content: 47.35

Gene sequence:

>942_bases
ATGGCTTCGCAAAATACAGAAAAAGATTTAAGCACGGTTGCCGATGAGACAATCGATAGCGTGAACCAATTCGTGGAGTA
CTTTAAAGATACAGATATGTGGATTGGTTTAGGGATCAAGCTCGCCGGTGTGGCGCTGATCATCCTTGGTTTATATATCG
CAACGCGCATTTTGACGACGATGGTCGAGCGCGTGTTTACACTCCGCAAAATAAAAGAACATGATATCGTCGCCCAGCGA
CAGAATGAAACGTTATTAAAACTGGCACAAAACACAATCCGCTATGTGATCGGGTTGATTATGGTCTTGACGGTGCTTGG
ACAATTCGGCGTGAATATCGCCGGTTTGATTGCATCAGCCGGGGTCGCAGGTCTTGCGATTTCATTCGGGGCACAAAGTT
TGGTGAAAGACGTCATCACAGGGGCGTTTATCATCTTTGAAAACCAATATAAGAACGGGGATTACGTCAATTTGAACCAA
CAAGTCGACGGGACGGTCATCGAGGTCGGAATCCGGACGACGAAGTTAAAAGGATTGAACGGGCAAGTGACGATTATTCC
GAACGGACAAATCTTACAAGTGACGAACTACTCGCTTGAAAACAGCGTCGCCGTGGTCGATATTGGGGTCGCATACGAAG
AAGATATGTCAAAAGTAGAGCAAGCGCTCAAAGAAATTGCGAAAACGGTCGAAGCACGCTATCACGACTTGTTCATCAAA
CCAATCGACTTAGCTGGAGTACAGTCGCTCGGACCGTCGGAAGTGGTGTACCGATTAATGGCGGAAGTCCCGCCGACCCA
ACATTTCGCAGCTGGTCGAATTTTGCATAAAGAGTTAAAGGCTGGACTTGACGAGCGGGGGATTGAAATTCCATACCCAC
GTACGGTCATGATGCCACCGAACTCGGCTCCTAAAGGAGGAGAAGCAGAAAATGCAAAGTAA

Upstream 100 bases:

>100_bases
TTCCCAAAAGTGGAAAACTTCTAACTTCCGAATGCAGCGTTTGAGAAAAGTCGTGAAATATGTTTTGATGATTTAGAATC
TACGACTTTGAGGTGAAAAG

Downstream 100 bases:

>100_bases
AACGTATGCATTGAACGATGTGGTGGAAATGAAAAAACCGCATGCCTGTAAGACGAACCGCTGGCAAATCACGCGTGTCG
GGATGGACATTCGAATCAAG

Product: MscS Mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MASQNTEKDLSTVADETIDSVNQFVEYFKDTDMWIGLGIKLAGVALIILGLYIATRILTTMVERVFTLRKIKEHDIVAQR
QNETLLKLAQNTIRYVIGLIMVLTVLGQFGVNIAGLIASAGVAGLAISFGAQSLVKDVITGAFIIFENQYKNGDYVNLNQ
QVDGTVIEVGIRTTKLKGLNGQVTIIPNGQILQVTNYSLENSVAVVDIGVAYEEDMSKVEQALKEIAKTVEARYHDLFIK
PIDLAGVQSLGPSEVVYRLMAEVPPTQHFAAGRILHKELKAGLDERGIEIPYPRTVMMPPNSAPKGGEAENAK

Sequences:

>Translated_313_residues
MASQNTEKDLSTVADETIDSVNQFVEYFKDTDMWIGLGIKLAGVALIILGLYIATRILTTMVERVFTLRKIKEHDIVAQR
QNETLLKLAQNTIRYVIGLIMVLTVLGQFGVNIAGLIASAGVAGLAISFGAQSLVKDVITGAFIIFENQYKNGDYVNLNQ
QVDGTVIEVGIRTTKLKGLNGQVTIIPNGQILQVTNYSLENSVAVVDIGVAYEEDMSKVEQALKEIAKTVEARYHDLFIK
PIDLAGVQSLGPSEVVYRLMAEVPPTQHFAAGRILHKELKAGLDERGIEIPYPRTVMMPPNSAPKGGEAENAK
>Mature_312_residues
ASQNTEKDLSTVADETIDSVNQFVEYFKDTDMWIGLGIKLAGVALIILGLYIATRILTTMVERVFTLRKIKEHDIVAQRQ
NETLLKLAQNTIRYVIGLIMVLTVLGQFGVNIAGLIASAGVAGLAISFGAQSLVKDVITGAFIIFENQYKNGDYVNLNQQ
VDGTVIEVGIRTTKLKGLNGQVTIIPNGQILQVTNYSLENSVAVVDIGVAYEEDMSKVEQALKEIAKTVEARYHDLFIKP
IDLAGVQSLGPSEVVYRLMAEVPPTQHFAAGRILHKELKAGLDERGIEIPYPRTVMMPPNSAPKGGEAENAK

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=272, Percent_Identity=32.3529411764706, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789291, Length=263, Percent_Identity=29.6577946768061, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1786670, Length=139, Percent_Identity=30.2158273381295, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787591, Length=185, Percent_Identity=23.2432432432432, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 34172; Mature: 34041

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQNTEKDLSTVADETIDSVNQFVEYFKDTDMWIGLGIKLAGVALIILGLYIATRILTT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
MVERVFTLRKIKEHDIVAQRQNETLLKLAQNTIRYVIGLIMVLTVLGQFGVNIAGLIASA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GVAGLAISFGAQSLVKDVITGAFIIFENQYKNGDYVNLNQQVDGTVIEVGIRTTKLKGLN
CHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEECCCCCCEEEEEECEEEEECCCC
GQVTIIPNGQILQVTNYSLENSVAVVDIGVAYEEDMSKVEQALKEIAKTVEARYHDLFIK
CEEEEEECCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
PIDLAGVQSLGPSEVVYRLMAEVPPTQHFAAGRILHKELKAGLDERGIEIPYPRTVMMPP
CCCHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECC
NSAPKGGEAENAK
CCCCCCCCCCCCC
>Mature Secondary Structure 
ASQNTEKDLSTVADETIDSVNQFVEYFKDTDMWIGLGIKLAGVALIILGLYIATRILTT
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
MVERVFTLRKIKEHDIVAQRQNETLLKLAQNTIRYVIGLIMVLTVLGQFGVNIAGLIASA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GVAGLAISFGAQSLVKDVITGAFIIFENQYKNGDYVNLNQQVDGTVIEVGIRTTKLKGLN
CHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEECCCCCCEEEEEECEEEEECCCC
GQVTIIPNGQILQVTNYSLENSVAVVDIGVAYEEDMSKVEQALKEIAKTVEARYHDLFIK
CEEEEEECCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
PIDLAGVQSLGPSEVVYRLMAEVPPTQHFAAGRILHKELKAGLDERGIEIPYPRTVMMPP
CCCHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECC
NSAPKGGEAENAK
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]