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The map label for this gene is rsmA [H]

Identifier: 229917418

GI number: 229917418

Start: 1644000

End: 1644878

Strand: Reverse

Name: rsmA [H]

Synonym: EAT1b_1693

Alternate gene names: 229917418

Gene position: 1644878-1644000 (Counterclockwise)

Preceding gene: 229917419

Following gene: 229917417

Centisome position: 54.83

GC content: 45.73

Gene sequence:

>879_bases
TTGAAAGACATTGCAACAATCCAACGAACGAAAGCGATTTTAGAGCGACATGGGTTTTCATTCAAAAAATCGCTCGGTCA
AAACTTTTTAATCGATTTGAACATCTTGAGTAAGATTGTCGGAGCAGCAGAACTGAGTGAAGTGAGTGGTGTCCTTGAAA
TCGGTCCCGGAATCGGCTCATTGACCGAACAATCGGCCAAGCGTGCCAAAAAGGTCGTTGCGCTTGAAATCGACCAACGT
CTTTTGCCGATTTTAGACGATACGATGTCGCCTTATCCGCATGTGAAAGTCATTCATGGGGATGCACTGGAACTAGACTT
ACGGGAGATCGTGGAGCAAGAATTTTTAAACGAAGGCATTGAAGATATTTCGGTTGTCGCCAACTTACCTTACTATGTCA
CGACACCGATCATTATGCGATTGCTTGAGAGCGGTGTTAAGTTCCGTTCGCTCGTCATGATGATTCAAAAAGAAGTGGCA
GAACGGATTGGAGCAAAACCTGGCACGAAAGCATACGGCTCGCTATCGATTGCGATTCAGTATTATGCGGAGGCAGAAGT
CAGTTTCATCGTCCCGAAAAACGTGTTCATCCCAGCACCGAACGTCGATTCGGCCGTCATTACACTACGAATGCGTAAAG
AGCCGGCCGTACAAGTGAAAGATGAGGCATTTTTCTTTGATGTGGCCCGAGCAAGCTTCGCTCAGCGCCGTAAAACCATC
CTGAACAATTTGACAAACTATATCGGGAAAGAACATAAGGTCGAACTCGAACGTTCGCTTCACGAGGCTGGAATCGATCC
GAAACGTCGTGGAGAGACGTTAAGCCTAGAAGAATTCGCACGTTTGTCTGACACAATTTTACCACTTAAAAATAGTTGA

Upstream 100 bases:

>100_bases
GTGAGCCGAATGCCAAACAATTTGTAAAACGGGTCGAGGCGCTCGGCGTCACGATCGAAGAGTGGGAGCAGGCACTTGCT
CAATTAGAGGAGGAACAGGG

Downstream 100 bases:

>100_bases
CGACCTGAAAACGAGTCGTTATAATATTAATCTTTATTTTCATATTCAATTATGCTATACTTGTAACAGTGAGGTGAAGC
GTATGCCAAAGACGTTACAA

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKDIATIQRTKAILERHGFSFKKSLGQNFLIDLNILSKIVGAAELSEVSGVLEIGPGIGSLTEQSAKRAKKVVALEIDQR
LLPILDDTMSPYPHVKVIHGDALELDLREIVEQEFLNEGIEDISVVANLPYYVTTPIIMRLLESGVKFRSLVMMIQKEVA
ERIGAKPGTKAYGSLSIAIQYYAEAEVSFIVPKNVFIPAPNVDSAVITLRMRKEPAVQVKDEAFFFDVARASFAQRRKTI
LNNLTNYIGKEHKVELERSLHEAGIDPKRRGETLSLEEFARLSDTILPLKNS

Sequences:

>Translated_292_residues
MKDIATIQRTKAILERHGFSFKKSLGQNFLIDLNILSKIVGAAELSEVSGVLEIGPGIGSLTEQSAKRAKKVVALEIDQR
LLPILDDTMSPYPHVKVIHGDALELDLREIVEQEFLNEGIEDISVVANLPYYVTTPIIMRLLESGVKFRSLVMMIQKEVA
ERIGAKPGTKAYGSLSIAIQYYAEAEVSFIVPKNVFIPAPNVDSAVITLRMRKEPAVQVKDEAFFFDVARASFAQRRKTI
LNNLTNYIGKEHKVELERSLHEAGIDPKRRGETLSLEEFARLSDTILPLKNS
>Mature_292_residues
MKDIATIQRTKAILERHGFSFKKSLGQNFLIDLNILSKIVGAAELSEVSGVLEIGPGIGSLTEQSAKRAKKVVALEIDQR
LLPILDDTMSPYPHVKVIHGDALELDLREIVEQEFLNEGIEDISVVANLPYYVTTPIIMRLLESGVKFRSLVMMIQKEVA
ERIGAKPGTKAYGSLSIAIQYYAEAEVSFIVPKNVFIPAPNVDSAVITLRMRKEPAVQVKDEAFFFDVARASFAQRRKTI
LNNLTNYIGKEHKVELERSLHEAGIDPKRRGETLSLEEFARLSDTILPLKNS

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Homo sapiens, GI7657198, Length=226, Percent_Identity=34.5132743362832, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI156415992, Length=282, Percent_Identity=32.9787234042553, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1786236, Length=280, Percent_Identity=32.1428571428571, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25141369, Length=282, Percent_Identity=30.1418439716312, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25146882, Length=249, Percent_Identity=30.9236947791165, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324989, Length=223, Percent_Identity=32.2869955156951, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21358017, Length=230, Percent_Identity=35.2173913043478, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357273, Length=279, Percent_Identity=29.0322580645161, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 32573; Mature: 32573

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01131 RRNA_A_DIMETH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIATIQRTKAILERHGFSFKKSLGQNFLIDLNILSKIVGAAELSEVSGVLEIGPGIGS
CCCHHHHHHHHHHHHHCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCH
LTEQSAKRAKKVVALEIDQRLLPILDDTMSPYPHVKVIHGDALELDLREIVEQEFLNEGI
HHHHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCH
EDISVVANLPYYVTTPIIMRLLESGVKFRSLVMMIQKEVAERIGAKPGTKAYGSLSIAIQ
HHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
YYAEAEVSFIVPKNVFIPAPNVDSAVITLRMRKEPAVQVKDEAFFFDVARASFAQRRKTI
EEECCEEEEEECCCEEECCCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHH
LNNLTNYIGKEHKVELERSLHEAGIDPKRRGETLSLEEFARLSDTILPLKNS
HHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKDIATIQRTKAILERHGFSFKKSLGQNFLIDLNILSKIVGAAELSEVSGVLEIGPGIGS
CCCHHHHHHHHHHHHHCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCH
LTEQSAKRAKKVVALEIDQRLLPILDDTMSPYPHVKVIHGDALELDLREIVEQEFLNEGI
HHHHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCH
EDISVVANLPYYVTTPIIMRLLESGVKFRSLVMMIQKEVAERIGAKPGTKAYGSLSIAIQ
HHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
YYAEAEVSFIVPKNVFIPAPNVDSAVITLRMRKEPAVQVKDEAFFFDVARASFAQRRKTI
EEECCEEEEEECCCEEECCCCCCCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHH
LNNLTNYIGKEHKVELERSLHEAGIDPKRRGETLSLEEFARLSDTILPLKNS
HHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA