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The map label for this gene is rocF [H]

Identifier: 229917321

GI number: 229917321

Start: 1547915

End: 1548817

Strand: Reverse

Name: rocF [H]

Synonym: EAT1b_1596

Alternate gene names: 229917321

Gene position: 1548817-1547915 (Counterclockwise)

Preceding gene: 229917322

Following gene: 229917320

Centisome position: 51.63

GC content: 47.07

Gene sequence:

>903_bases
ATGCAATGGTCATATATTCACGTGCCGCTGCGTTACGGTCAGGGGAAATTAGGGGTCGATCAAGGACCGACAAAGTTAAA
TGAAATGGGGATGCAACAACTCCTTCCAACAGAAACGGTCAAACATACGATTCGTGTCTTGCCGGAATCTGAAATTCGAG
AAAATGAAGAACATTTAAAACGGGTCGATGGTGTCCTGCATACCGTCACGGAATTAGCAGAAGTCGTACATCGTGAGATT
TCAGAAAAACGATTCCCATTGATCGTTGGGGGCGATCATAGTATGGCAATCGGTACTCTTGCTGGATTGGCTCAAACAGG
CCCTTATGGAGTCGTTTGGGTGGATGCTCACGCTGACTTGAATACAGGCGAAACGTCACCATCGGGGAACATTCACGGAA
TGCCACTTGCGGCAGCGATGGGGATGGGCGACGTGCGTCTGACAGAAGTGGGCGGACGTGATCCGAAGCTATCACCAGAG
CACTTAGTTTATATTGCCCTGCGTGATATCGATGAAGGAGAAATGAATGAAATCAATCGACTCGGCATCAAAGTCATTAC
AGTAGAAGAAGTACGTACGCGTGGTGTGGATGTCATCATGCAAGAGGCAATGCGTTATCTTCGTGAACGAGTAGACCGTT
TTTATATCAGTTTCGATATGGATAGTCTCGATGCATCCCTCGTTCCTGGAACAGGTACACCGGTTGACGGCGGTTTAACA
GAAGTCGAAGCCAAAGCGATTTTAAAAGAAGCGATGCAAGCAGAAGACTTGATTGCAGTAGAGCTCGTCGAGTTAAATCC
GGCATTAGACCGAGATGACGTGACGGCTCAGTTGGCCTATCGCCTATGTGAAACGATTATTAAATCTAAAGAAAACCTGT
TATTGGAAGGCGAAACCGTCTGA

Upstream 100 bases:

>100_bases
GGCTGCCTTTTTGCATGTTTATTCATCATTCTGCCGAGTTGAACCAAACAAATGATAGCGTTTACAATTTAACTATCAAG
CGTATAAAGGGGGAATGGCG

Downstream 100 bases:

>100_bases
TTTCCTTACAGTTTCCAAACCCGTTTGCTACAATGGGGATGGAAACTTTTTTTGATTTTTTTTGAAACCATTTCAATATC
AAGACGTATATAGAGATGAC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MQWSYIHVPLRYGQGKLGVDQGPTKLNEMGMQQLLPTETVKHTIRVLPESEIRENEEHLKRVDGVLHTVTELAEVVHREI
SEKRFPLIVGGDHSMAIGTLAGLAQTGPYGVVWVDAHADLNTGETSPSGNIHGMPLAAAMGMGDVRLTEVGGRDPKLSPE
HLVYIALRDIDEGEMNEINRLGIKVITVEEVRTRGVDVIMQEAMRYLRERVDRFYISFDMDSLDASLVPGTGTPVDGGLT
EVEAKAILKEAMQAEDLIAVELVELNPALDRDDVTAQLAYRLCETIIKSKENLLLEGETV

Sequences:

>Translated_300_residues
MQWSYIHVPLRYGQGKLGVDQGPTKLNEMGMQQLLPTETVKHTIRVLPESEIRENEEHLKRVDGVLHTVTELAEVVHREI
SEKRFPLIVGGDHSMAIGTLAGLAQTGPYGVVWVDAHADLNTGETSPSGNIHGMPLAAAMGMGDVRLTEVGGRDPKLSPE
HLVYIALRDIDEGEMNEINRLGIKVITVEEVRTRGVDVIMQEAMRYLRERVDRFYISFDMDSLDASLVPGTGTPVDGGLT
EVEAKAILKEAMQAEDLIAVELVELNPALDRDDVTAQLAYRLCETIIKSKENLLLEGETV
>Mature_300_residues
MQWSYIHVPLRYGQGKLGVDQGPTKLNEMGMQQLLPTETVKHTIRVLPESEIRENEEHLKRVDGVLHTVTELAEVVHREI
SEKRFPLIVGGDHSMAIGTLAGLAQTGPYGVVWVDAHADLNTGETSPSGNIHGMPLAAAMGMGDVRLTEVGGRDPKLSPE
HLVYIALRDIDEGEMNEINRLGIKVITVEEVRTRGVDVIMQEAMRYLRERVDRFYISFDMDSLDASLVPGTGTPVDGGLT
EVEAKAILKEAMQAEDLIAVELVELNPALDRDDVTAQLAYRLCETIIKSKENLLLEGETV

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=274, Percent_Identity=37.2262773722628, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI4502215, Length=303, Percent_Identity=33.6633663366337, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=27.1477663230241, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1789306, Length=192, Percent_Identity=28.125, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996843, Length=240, Percent_Identity=38.75, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325146, Length=303, Percent_Identity=34.3234323432343, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24638886, Length=278, Percent_Identity=33.0935251798561, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 33112; Mature: 33112

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWSYIHVPLRYGQGKLGVDQGPTKLNEMGMQQLLPTETVKHTIRVLPESEIRENEEHLK
CCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCHHHHH
RVDGVLHTVTELAEVVHREISEKRFPLIVGGDHSMAIGTLAGLAQTGPYGVVWVDAHADL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
NTGETSPSGNIHGMPLAAAMGMGDVRLTEVGGRDPKLSPEHLVYIALRDIDEGEMNEINR
CCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
LGIKVITVEEVRTRGVDVIMQEAMRYLRERVDRFYISFDMDSLDASLVPGTGTPVDGGLT
CCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCCCCCCCCHH
EVEAKAILKEAMQAEDLIAVELVELNPALDRDDVTAQLAYRLCETIIKSKENLLLEGETV
HHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure
MQWSYIHVPLRYGQGKLGVDQGPTKLNEMGMQQLLPTETVKHTIRVLPESEIRENEEHLK
CCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCHHHHH
RVDGVLHTVTELAEVVHREISEKRFPLIVGGDHSMAIGTLAGLAQTGPYGVVWVDAHADL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
NTGETSPSGNIHGMPLAAAMGMGDVRLTEVGGRDPKLSPEHLVYIALRDIDEGEMNEINR
CCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
LGIKVITVEEVRTRGVDVIMQEAMRYLRERVDRFYISFDMDSLDASLVPGTGTPVDGGLT
CCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCCCCCCCCHH
EVEAKAILKEAMQAEDLIAVELVELNPALDRDDVTAQLAYRLCETIIKSKENLLLEGETV
HHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]