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The map label for this gene is yhdH [H]

Identifier: 229917211

GI number: 229917211

Start: 1456025

End: 1457017

Strand: Direct

Name: yhdH [H]

Synonym: EAT1b_1486

Alternate gene names: 229917211

Gene position: 1456025-1457017 (Clockwise)

Preceding gene: 229917209

Following gene: 229917216

Centisome position: 48.54

GC content: 52.67

Gene sequence:

>993_bases
ATGAATGAATCATTCCAAGCACTCGTGCTCGACCAGCACGAGGAACGCCTTCATGCCGAAGTAAAAGAAGTACAAGCCGA
TGTCCTTCCGAAAGAAGAGGACGGAAATGTGTTAGTGGAAGTTCACTACTCTGCGTTGAACTATAAAGACGCGCTCGGAT
TAACGACTTCTGGTAAAATCGTCAATCGCTATCCGTTCATTCCGGGATGCGAATTCGTTGGAACTGTCGTCGAATCAGAC
TACCTCGACATCAAAGTTGGCGACGAGGTAATCGCCACTGGTTTCGGGATTGGGGAACGGCACTTCGGTGGATTTAGCCA
GTATGCGCAAGTACCGGGGAAATGGCTCGTGAAGTTACCGAAAGGAATGAGCATGCGAGATGCAATCGCCATCGGAACAC
CAGGACTTACCGCCATGCTTTCCATTGATGCACTCGAACACGCAGGTGTGCGTCCGGGTGAAGAAGTACTTGTCACAGGC
GCGACAGGTGGTGTCGGAAGCTTCGCGATTACGTTGCTTCGTCGTCTCGGCTACCATGTCGTCGCCTCCACCGGCAAAAC
AGATTCACCATACTTACGCTCACTCGGTGTCGAGACGATCATCGATCGAAGCGAATTAGAAGGCCCTGCCCGTCCCCTCG
CCAAGCAACGTTTCGATGCCGCCATTGATTCGGTCGGTGGAAATACACTCGCCAACATCTTGAGTCAGATACGATATGAA
GGTGCTGTCGCCGCATGCGGTCTCGTCGGAGGCGCAGAGTTGCCAACGAGCGTCTATCCGTTTATTTTACGCGGCGTGAA
GCTCATCGGCATCGATTCGGTCATGCAACCCATGGTTCGTCGTACGAACGCATGGGAACGTCTCGAAGAACTCATCGACC
TGAAAGTCCTCAATGAGATGATCCATGAGATTCCGTTACACGACGTCCTTCGCCACGCCGAAGCGATGATGCGTGGTGAA
TTGAGCGGTCGCACCATCGTTCGTCTTCGCTAA

Upstream 100 bases:

>100_bases
ACTCTCTACCCGTTTCCCCCTAAAGATTCGTGCATATATTTCATTTTGCGAGGGAAAGACTGTTAGAGTGAAGACATCCA
TAGGAAAAGAGGTTAAGCAG

Downstream 100 bases:

>100_bases
GCCCATCAAAAGAGGCTGAATCATTCACGATTCAGCCTCTTTCCTCTCTATTCTCCATGGTGTGGAATCAGATAGTGAAT
CCGGCAGGTGCGTCTTTCAC

Product: quinone oxidoreductase, YhdH/YhfP family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNESFQALVLDQHEERLHAEVKEVQADVLPKEEDGNVLVEVHYSALNYKDALGLTTSGKIVNRYPFIPGCEFVGTVVESD
YLDIKVGDEVIATGFGIGERHFGGFSQYAQVPGKWLVKLPKGMSMRDAIAIGTPGLTAMLSIDALEHAGVRPGEEVLVTG
ATGGVGSFAITLLRRLGYHVVASTGKTDSPYLRSLGVETIIDRSELEGPARPLAKQRFDAAIDSVGGNTLANILSQIRYE
GAVAACGLVGGAELPTSVYPFILRGVKLIGIDSVMQPMVRRTNAWERLEELIDLKVLNEMIHEIPLHDVLRHAEAMMRGE
LSGRTIVRLR

Sequences:

>Translated_330_residues
MNESFQALVLDQHEERLHAEVKEVQADVLPKEEDGNVLVEVHYSALNYKDALGLTTSGKIVNRYPFIPGCEFVGTVVESD
YLDIKVGDEVIATGFGIGERHFGGFSQYAQVPGKWLVKLPKGMSMRDAIAIGTPGLTAMLSIDALEHAGVRPGEEVLVTG
ATGGVGSFAITLLRRLGYHVVASTGKTDSPYLRSLGVETIIDRSELEGPARPLAKQRFDAAIDSVGGNTLANILSQIRYE
GAVAACGLVGGAELPTSVYPFILRGVKLIGIDSVMQPMVRRTNAWERLEELIDLKVLNEMIHEIPLHDVLRHAEAMMRGE
LSGRTIVRLR
>Mature_330_residues
MNESFQALVLDQHEERLHAEVKEVQADVLPKEEDGNVLVEVHYSALNYKDALGLTTSGKIVNRYPFIPGCEFVGTVVESD
YLDIKVGDEVIATGFGIGERHFGGFSQYAQVPGKWLVKLPKGMSMRDAIAIGTPGLTAMLSIDALEHAGVRPGEEVLVTG
ATGGVGSFAITLLRRLGYHVVASTGKTDSPYLRSLGVETIIDRSELEGPARPLAKQRFDAAIDSVGGNTLANILSQIRYE
GAVAACGLVGGAELPTSVYPFILRGVKLIGIDSVMQPMVRRTNAWERLEELIDLKVLNEMIHEIPLHDVLRHAEAMMRGE
LSGRTIVRLR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=246, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI13236495, Length=246, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI194239676, Length=173, Percent_Identity=31.2138728323699, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI47519420, Length=238, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI28557745, Length=361, Percent_Identity=22.9916897506925, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI226056130, Length=186, Percent_Identity=30.1075268817204, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI226059159, Length=186, Percent_Identity=30.1075268817204, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI226059133, Length=186, Percent_Identity=30.1075268817204, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI67078404, Length=346, Percent_Identity=25.1445086705202, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1789651, Length=327, Percent_Identity=47.7064220183486, Blast_Score=301, Evalue=6e-83,
Organism=Caenorhabditis elegans, GI71988145, Length=329, Percent_Identity=24.3161094224924, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=363, Percent_Identity=25.3443526170799, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=354, Percent_Identity=23.1638418079096, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=328, Percent_Identity=22.8658536585366, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35885; Mature: 35885

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESFQALVLDQHEERLHAEVKEVQADVLPKEEDGNVLVEVHYSALNYKDALGLTTSGKI
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECHHCHHHHCCCCCCCCC
VNRYPFIPGCEFVGTVVESDYLDIKVGDEVIATGFGIGERHFGGFSQYAQVPGKWLVKLP
CCCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHCCCCCCHHCCCHHHHHHCCCCEEEECC
KGMSMRDAIAIGTPGLTAMLSIDALEHAGVRPGEEVLVTGATGGVGSFAITLLRRLGYHV
CCCCHHHEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEE
VASTGKTDSPYLRSLGVETIIDRSELEGPARPLAKQRFDAAIDSVGGNTLANILSQIRYE
EECCCCCCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GAVAACGLVGGAELPTSVYPFILRGVKLIGIDSVMQPMVRRTNAWERLEELIDLKVLNEM
CHHHHHHHCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IHEIPLHDVLRHAEAMMRGELSGRTIVRLR
HHHCCHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MNESFQALVLDQHEERLHAEVKEVQADVLPKEEDGNVLVEVHYSALNYKDALGLTTSGKI
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECHHCHHHHCCCCCCCCC
VNRYPFIPGCEFVGTVVESDYLDIKVGDEVIATGFGIGERHFGGFSQYAQVPGKWLVKLP
CCCCCCCCCHHHHHHHHCCCCEEEEECCHHHHHCCCCCCHHCCCHHHHHHCCCCEEEECC
KGMSMRDAIAIGTPGLTAMLSIDALEHAGVRPGEEVLVTGATGGVGSFAITLLRRLGYHV
CCCCHHHEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEE
VASTGKTDSPYLRSLGVETIIDRSELEGPARPLAKQRFDAAIDSVGGNTLANILSQIRYE
EECCCCCCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GAVAACGLVGGAELPTSVYPFILRGVKLIGIDSVMQPMVRRTNAWERLEELIDLKVLNEM
CHHHHHHHCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IHEIPLHDVLRHAEAMMRGELSGRTIVRLR
HHHCCHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]