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The map label for this gene is arcB [H]

Identifier: 229917201

GI number: 229917201

Start: 1445483

End: 1446511

Strand: Reverse

Name: arcB [H]

Synonym: EAT1b_1476

Alternate gene names: 229917201

Gene position: 1446511-1445483 (Counterclockwise)

Preceding gene: 229917202

Following gene: 229917200

Centisome position: 48.22

GC content: 49.66

Gene sequence:

>1029_bases
ATGTCTACAACGTTCAATTTTGATTTGAAAGGTCGTCATTTTTTATCGCTAAACGAGTTTTCGGGTGAAGAAATCAACTA
CTTGATCGATTTGTCTGCTGCATTCAAACGTCAGAAAAAACAAGGTGTTCCACATCGGATTTGTGAAGGTAAAAACATTG
CCTTGCTCTTTGAAAAACCATCGACGCGGACGCGGTGTGCGTTTACCGTTGCTGCCATCGATTTAGGGATGCATCCCGAA
TATTTAGGCAAGAATGACATTCAATTCGGGAAGAAAGAATCGGTGCGCGATACCGCAATCGTCCTCGGGCGCATGTTTGA
CGGCATTCAGTTCCGTGGCTTCGCCCACGAGACGGTCGAAGGTCTTGCGAAAGACGCAGGCGTACCGGTATGGAACGGCT
TGACCGACTTGTATCACCCGACCCAAATCTTGGCTGACTTTTTGACGGTGAAAGAACAAAAAGGAGAACTTGCCGGAATC
AAATTCGTGTACGTGGGCGACGGACGGAACAACATGGGCAACACGCTGTTGATCGGTGGTGCAAAAGTAGGAATGGATAT
GCGGATCTGTGCACCGAAATCGCTCTGGCCATCTGACGAAATCGTGAACTATGCGAAGTCGGTCGCTGCTGAAACCGGTG
CTGTGATCACCTTGACGGAGAGCATTGAGAAAGCGATGAATCAAGCGGACGTCGTCTACACGGATGTCTGGGTATCGATG
GGCGAGGAAGCGGCATTCGCAGAACGGATTGAACTGTTGCGACCATATCAAGTGAACATGGACATGCTTCAAAAGAGTGG
CAATCCAGACATCATGTTCTTACATTGCCTCCCTGCCTTCCACGACTTAGAAACGGAAGTCGGTCGAGCGATTCACGAAC
AGTACGGGTTGACGGAAATGGAAGTGACCGATGAAGTGTTCCGCAGTCGTCATTCGTTCGTATTTGATGAGGCGGAAAAC
CGGATGCATACCATCAAGGCGGTGATGGCGGCGACGCTCACGGAGACACGCGAATGGCTTGATCGTTGA

Upstream 100 bases:

>100_bases
AATCATGTCGAGTGAACTATCGCGCGGACGTGGGGGTCCACGTTGCATGAGTTGTCCGATTATCCGCCAAGACATCTAAA
TGTGATAAGGAGGAAGCAGT

Downstream 100 bases:

>100_bases
CGAGGAGGGGATTCCCCCTCCTGCTTTAAAATAAGCGAAAGGGATGAGTAGAATGTCTACGAAGTTGGAGCATGACTCAG
GTGGTTCGGCTGGAGTACAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSTTFNFDLKGRHFLSLNEFSGEEINYLIDLSAAFKRQKKQGVPHRICEGKNIALLFEKPSTRTRCAFTVAAIDLGMHPE
YLGKNDIQFGKKESVRDTAIVLGRMFDGIQFRGFAHETVEGLAKDAGVPVWNGLTDLYHPTQILADFLTVKEQKGELAGI
KFVYVGDGRNNMGNTLLIGGAKVGMDMRICAPKSLWPSDEIVNYAKSVAAETGAVITLTESIEKAMNQADVVYTDVWVSM
GEEAAFAERIELLRPYQVNMDMLQKSGNPDIMFLHCLPAFHDLETEVGRAIHEQYGLTEMEVTDEVFRSRHSFVFDEAEN
RMHTIKAVMAATLTETREWLDR

Sequences:

>Translated_342_residues
MSTTFNFDLKGRHFLSLNEFSGEEINYLIDLSAAFKRQKKQGVPHRICEGKNIALLFEKPSTRTRCAFTVAAIDLGMHPE
YLGKNDIQFGKKESVRDTAIVLGRMFDGIQFRGFAHETVEGLAKDAGVPVWNGLTDLYHPTQILADFLTVKEQKGELAGI
KFVYVGDGRNNMGNTLLIGGAKVGMDMRICAPKSLWPSDEIVNYAKSVAAETGAVITLTESIEKAMNQADVVYTDVWVSM
GEEAAFAERIELLRPYQVNMDMLQKSGNPDIMFLHCLPAFHDLETEVGRAIHEQYGLTEMEVTDEVFRSRHSFVFDEAEN
RMHTIKAVMAATLTETREWLDR
>Mature_341_residues
STTFNFDLKGRHFLSLNEFSGEEINYLIDLSAAFKRQKKQGVPHRICEGKNIALLFEKPSTRTRCAFTVAAIDLGMHPEY
LGKNDIQFGKKESVRDTAIVLGRMFDGIQFRGFAHETVEGLAKDAGVPVWNGLTDLYHPTQILADFLTVKEQKGELAGIK
FVYVGDGRNNMGNTLLIGGAKVGMDMRICAPKSLWPSDEIVNYAKSVAAETGAVITLTESIEKAMNQADVVYTDVWVSMG
EEAAFAERIELLRPYQVNMDMLQKSGNPDIMFLHCLPAFHDLETEVGRAIHEQYGLTEMEVTDEVFRSRHSFVFDEAENR
MHTIKAVMAATLTETREWLDR

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=335, Percent_Identity=39.7014925373134, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI18105007, Length=336, Percent_Identity=25.5952380952381, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1790703, Length=331, Percent_Identity=55.2870090634441, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1786469, Length=335, Percent_Identity=53.7313432835821, Blast_Score=352, Evalue=2e-98,
Organism=Escherichia coli, GI48994908, Length=368, Percent_Identity=25, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367364, Length=309, Percent_Identity=28.4789644012945, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193204318, Length=234, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322373, Length=346, Percent_Identity=35.2601156069364, Blast_Score=189, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6322331, Length=167, Percent_Identity=31.7365269461078, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24642586, Length=235, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 38427; Mature: 38296

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTFNFDLKGRHFLSLNEFSGEEINYLIDLSAAFKRQKKQGVPHRICEGKNIALLFEKP
CCCEEEEECCCCEEEEEECCCCCCEEEEEECHHHHHHHHHCCCCHHHCCCCCEEEEEECC
STRTRCAFTVAAIDLGMHPEYLGKNDIQFGKKESVRDTAIVLGRMFDGIQFRGFAHETVE
CCCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCHHHHHH
GLAKDAGVPVWNGLTDLYHPTQILADFLTVKEQKGELAGIKFVYVGDGRNNMGNTLLIGG
HHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEC
AKVGMDMRICAPKSLWPSDEIVNYAKSVAAETGAVITLTESIEKAMNQADVVYTDVWVSM
CEECCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEEHHHHHC
GEEAAFAERIELLRPYQVNMDMLQKSGNPDIMFLHCLPAFHDLETEVGRAIHEQYGLTEM
CCHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHH
EVTDEVFRSRHSFVFDEAENRMHTIKAVMAATLTETREWLDR
HHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STTFNFDLKGRHFLSLNEFSGEEINYLIDLSAAFKRQKKQGVPHRICEGKNIALLFEKP
CCEEEEECCCCEEEEEECCCCCCEEEEEECHHHHHHHHHCCCCHHHCCCCCEEEEEECC
STRTRCAFTVAAIDLGMHPEYLGKNDIQFGKKESVRDTAIVLGRMFDGIQFRGFAHETVE
CCCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCHHHHHH
GLAKDAGVPVWNGLTDLYHPTQILADFLTVKEQKGELAGIKFVYVGDGRNNMGNTLLIGG
HHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCEEEEEC
AKVGMDMRICAPKSLWPSDEIVNYAKSVAAETGAVITLTESIEKAMNQADVVYTDVWVSM
CEECCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCEEEEHHHHHC
GEEAAFAERIELLRPYQVNMDMLQKSGNPDIMFLHCLPAFHDLETEVGRAIHEQYGLTEM
CCHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHH
EVTDEVFRSRHSFVFDEAENRMHTIKAVMAATLTETREWLDR
HHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9851988 [H]