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The map label for this gene is arcD [H]

Identifier: 229917200

GI number: 229917200

Start: 1443955

End: 1445430

Strand: Reverse

Name: arcD [H]

Synonym: EAT1b_1475

Alternate gene names: 229917200

Gene position: 1445430-1443955 (Counterclockwise)

Preceding gene: 229917201

Following gene: 229917199

Centisome position: 48.18

GC content: 49.86

Gene sequence:

>1476_bases
ATGTCTACGAAGTTGGAGCATGACTCAGGTGGTTCGGCTGGAGTACATCCTGAAAAGAAAGATAAGCGGTTAGGTCTCGG
AGCGTTGACGGCACTTGTCGTCGGGTCGATGATTGGCGGTGGCGCCTTTAACTTGGCTGCCGATTTGGCGCAAGGTGCGA
ATGCGGGTGCCATTCTTATTGGTTGGGTCATCACGGGAATCGGGATTATCGCGCTCGGTCTCAGTTTTCAAAATTTGACG
ATGCGTCGTCCAGATCTCGATGGTGGCGTATACAGCTATGCACGGGCAGGTTTTGGATCGTTCGTCGGATTTAACTCGGC
ATGGGGATATTGGTTGTCTGCCTGGCTTGGAAACGTGGCGTATGCCACACTGCTGTTCAGTTCGGTTGGTTATTTCTTCC
CGATTTTTGAAGGGGGACAGAATATCGCGTCGATTATTGGCGCATCGATTATGCTTTGGCTCGTGCATACACTCATCTTA
CGTGGGGTACATGAGGCATCGATGATCAACATCGTCACGACGATTGCCAAGCTCGTCCCAATTTTTGCATTCATTACGAT
TACCTTGTTCTTCTTTAATCTCGAAAACTTCACCTTCGATTTTTGGGGACAAGGTGGCTTCTCATGGGGAAGTGTTCGTG
ACCAAGTCGTTTCGACGATGCTCGTGACACTTTGGGTCTTTATCGGTGTGGAAGGGGCCGTCGTGCTATCTGGCCGTGCT
CGGAAACGTTCGGACGTCGGGAAAGCAACCGTTATTGGGCTACTTGGAACGCTCGTCATTTATTTGCTCATTTCTATCAT
GTCGCTCGGTCTCATGACTCCCGAAAATGTAGCGAACGCCTCGCAACCAGCGATGGCATATTTGCTCGAGTCGGCCGTCG
GTCCGTGGGGTGCGATGCTCATCAACGGGGGACTCGTCATCTCTGTCCTTGGCGCATGGCTCGGTTGGACGCTGTTAGCG
GCAGAAATCCCATTCGTTGCCGCCAAAGATGGAGTCTTCCCGAAATGGTTCACGAAAGAGAATCAAAATCAAGCTCCTGT
CAATGCCCTTTGGCTAACGAATGGGTTGATTCAGCTCTTCCTCTTCACATTCTTGATTTCAGATGCCGCATATAACTTTG
CCTTTTCTCTCGCTTCGAGTGCGATTTTGATCCCATACGTGTTCTCGGCCTTTTACCAAGTGAAAGTGGCGAAGAACGGA
ATCGGATACAGTTCCGGTGAACGAAAAACACGCGATTTAGCGATTGGATTGGTCGCTTCCGTTTATGGACTATGGCTCAT
TTACGCCGCTGGAATCGATTATTTACTTCTCACCACACTTTTATATGCACCCGGAACCCTTCTTTACATGAAGGCGCAAC
GTGAAAATGGCATCAAGTCACTCACTAAAACGGAATGGATGGTCGCCGGTGTGTTGACCGCACTCGCCATCTTCGCAGTC
GTACGCATACTATCGGGTAATATTTCAGTCATCTGA

Upstream 100 bases:

>100_bases
GTGATGGCGGCGACGCTCACGGAGACACGCGAATGGCTTGATCGTTGACGAGGAGGGGATTCCCCCTCCTGCTTTAAAAT
AAGCGAAAGGGATGAGTAGA

Downstream 100 bases:

>100_bases
TCGGGGGTATGGATATGGAGAAAAAACGAGTGGTCATCGCTTTAGGCGGGAATGCGATTCAACAAGGGAAAGATGCGACA
GCCGAAGCACAAATACAGGC

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSTKLEHDSGGSAGVHPEKKDKRLGLGALTALVVGSMIGGGAFNLAADLAQGANAGAILIGWVITGIGIIALGLSFQNLT
MRRPDLDGGVYSYARAGFGSFVGFNSAWGYWLSAWLGNVAYATLLFSSVGYFFPIFEGGQNIASIIGASIMLWLVHTLIL
RGVHEASMINIVTTIAKLVPIFAFITITLFFFNLENFTFDFWGQGGFSWGSVRDQVVSTMLVTLWVFIGVEGAVVLSGRA
RKRSDVGKATVIGLLGTLVIYLLISIMSLGLMTPENVANASQPAMAYLLESAVGPWGAMLINGGLVISVLGAWLGWTLLA
AEIPFVAAKDGVFPKWFTKENQNQAPVNALWLTNGLIQLFLFTFLISDAAYNFAFSLASSAILIPYVFSAFYQVKVAKNG
IGYSSGERKTRDLAIGLVASVYGLWLIYAAGIDYLLLTTLLYAPGTLLYMKAQRENGIKSLTKTEWMVAGVLTALAIFAV
VRILSGNISVI

Sequences:

>Translated_491_residues
MSTKLEHDSGGSAGVHPEKKDKRLGLGALTALVVGSMIGGGAFNLAADLAQGANAGAILIGWVITGIGIIALGLSFQNLT
MRRPDLDGGVYSYARAGFGSFVGFNSAWGYWLSAWLGNVAYATLLFSSVGYFFPIFEGGQNIASIIGASIMLWLVHTLIL
RGVHEASMINIVTTIAKLVPIFAFITITLFFFNLENFTFDFWGQGGFSWGSVRDQVVSTMLVTLWVFIGVEGAVVLSGRA
RKRSDVGKATVIGLLGTLVIYLLISIMSLGLMTPENVANASQPAMAYLLESAVGPWGAMLINGGLVISVLGAWLGWTLLA
AEIPFVAAKDGVFPKWFTKENQNQAPVNALWLTNGLIQLFLFTFLISDAAYNFAFSLASSAILIPYVFSAFYQVKVAKNG
IGYSSGERKTRDLAIGLVASVYGLWLIYAAGIDYLLLTTLLYAPGTLLYMKAQRENGIKSLTKTEWMVAGVLTALAIFAV
VRILSGNISVI
>Mature_490_residues
STKLEHDSGGSAGVHPEKKDKRLGLGALTALVVGSMIGGGAFNLAADLAQGANAGAILIGWVITGIGIIALGLSFQNLTM
RRPDLDGGVYSYARAGFGSFVGFNSAWGYWLSAWLGNVAYATLLFSSVGYFFPIFEGGQNIASIIGASIMLWLVHTLILR
GVHEASMINIVTTIAKLVPIFAFITITLFFFNLENFTFDFWGQGGFSWGSVRDQVVSTMLVTLWVFIGVEGAVVLSGRAR
KRSDVGKATVIGLLGTLVIYLLISIMSLGLMTPENVANASQPAMAYLLESAVGPWGAMLINGGLVISVLGAWLGWTLLAA
EIPFVAAKDGVFPKWFTKENQNQAPVNALWLTNGLIQLFLFTFLISDAAYNFAFSLASSAILIPYVFSAFYQVKVAKNGI
GYSSGERKTRDLAIGLVASVYGLWLIYAAGIDYLLLTTLLYAPGTLLYMKAQRENGIKSLTKTEWMVAGVLTALAIFAVV
RILSGNISVI

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=456, Percent_Identity=44.9561403508772, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI2367353, Length=417, Percent_Identity=28.7769784172662, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1786908, Length=441, Percent_Identity=26.984126984127, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790575, Length=332, Percent_Identity=26.8072289156627, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52574; Mature: 52443

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKLEHDSGGSAGVHPEKKDKRLGLGALTALVVGSMIGGGAFNLAADLAQGANAGAILI
CCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
GWVITGIGIIALGLSFQNLTMRRPDLDGGVYSYARAGFGSFVGFNSAWGYWLSAWLGNVA
HHHHHHHHHHHHHCCHHHCEEECCCCCCCHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHH
YATLLFSSVGYFFPIFEGGQNIASIIGASIMLWLVHTLILRGVHEASMINIVTTIAKLVP
HHHHHHHHHHHHEEHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IFAFITITLFFFNLENFTFDFWGQGGFSWGSVRDQVVSTMLVTLWVFIGVEGAVVLSGRA
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
RKRSDVGKATVIGLLGTLVIYLLISIMSLGLMTPENVANASQPAMAYLLESAVGPWGAML
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCHHHHH
INGGLVISVLGAWLGWTLLAAEIPFVAAKDGVFPKWFTKENQNQAPVNALWLTNGLIQLF
HCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LFTFLISDAAYNFAFSLASSAILIPYVFSAFYQVKVAKNGIGYSSGERKTRDLAIGLVAS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
VYGLWLIYAAGIDYLLLTTLLYAPGTLLYMKAQRENGIKSLTKTEWMVAGVLTALAIFAV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VRILSGNISVI
HHHHCCCCCCC
>Mature Secondary Structure 
STKLEHDSGGSAGVHPEKKDKRLGLGALTALVVGSMIGGGAFNLAADLAQGANAGAILI
CCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
GWVITGIGIIALGLSFQNLTMRRPDLDGGVYSYARAGFGSFVGFNSAWGYWLSAWLGNVA
HHHHHHHHHHHHHCCHHHCEEECCCCCCCHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHH
YATLLFSSVGYFFPIFEGGQNIASIIGASIMLWLVHTLILRGVHEASMINIVTTIAKLVP
HHHHHHHHHHHHEEHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IFAFITITLFFFNLENFTFDFWGQGGFSWGSVRDQVVSTMLVTLWVFIGVEGAVVLSGRA
HHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
RKRSDVGKATVIGLLGTLVIYLLISIMSLGLMTPENVANASQPAMAYLLESAVGPWGAML
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCHHHHH
INGGLVISVLGAWLGWTLLAAEIPFVAAKDGVFPKWFTKENQNQAPVNALWLTNGLIQLF
HCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LFTFLISDAAYNFAFSLASSAILIPYVFSAFYQVKVAKNGIGYSSGERKTRDLAIGLVAS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
VYGLWLIYAAGIDYLLLTTLLYAPGTLLYMKAQRENGIKSLTKTEWMVAGVLTALAIFAV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VRILSGNISVI
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9053381; 11792842 [H]