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The map label for this gene is trpB [H]

Identifier: 229917176

GI number: 229917176

Start: 1415945

End: 1417129

Strand: Reverse

Name: trpB [H]

Synonym: EAT1b_1450

Alternate gene names: 229917176

Gene position: 1417129-1415945 (Counterclockwise)

Preceding gene: 229917177

Following gene: 229917175

Centisome position: 47.24

GC content: 52.91

Gene sequence:

>1185_bases
ATGTATGCACAACCAGTGAACGGGAAGTTTGGACAATATGGTGGGAAGTACATTCCAGAGACGCTCATGCAGGCGGTCGA
AGAATTAGAGGTCGCTTATGAAGAGGCGAAGCAAGATCCTGAGTTTCAAGAACGATTCTCTTCCTTATTACGTGAATACG
TCGGACGTGAGACGCCACTTTATTATGCGTCGAACCTAAGTCGTCGCCTCGGGACGAATGTCTATTTGAAACGTGAAGAC
TTGAACCATACCGGTGCCCATAAGATCAACAATACGATCGGGCAGGCGCTCCTGGCGAAACGGATGGGGAAACAGAAAGT
CGTTGCGGAGACAGGCGCGGGACAACACGGTGTCGCGACGGCAACAGTATGCGCACTACTCGATTTAGAATGTACCATCT
TCATGGGTGAGGTCGATGTTGAACGCCAAGCATTGAACGTGTTTCGGATGGAACTACTCGGGGCGAAAGTCGTCCCTGTC
AAATCAGGCAGTCGCACCTTAAAGGATGCCGTCAATGAAGCGCTCCGTTACTGGGTCAAACATGTCGACGATACGCACTA
TGTGATGGGTTCCGTTCTCGGACCGCATCCATTCCCGCAGATGGTACGTGATTTCCAAAGCGTAATCGGGACAGAGACAC
GTCGTCAAATCCTCGAACAAACGGGACGCCTCCCGGATGCCGTCGTCGCTTGTGTCGGCGGAGGGAGCAACGCCATGGGC
ATGTTCTATCCGTTCTTGAACGATGAGTCGGTCGCACTCTACGGTGTCGAAGCGGCTGGAAGTGGCATCGATACGGATAA
ACACGCAGCAACCCTCACAAAAGGGGAAGTCGGTGTCTTACATGGGTCGCTCATGTATGTCCTGCAAGACGCAGCGGGTC
AAATCGAGGAAGCCCATTCCATTTCAGCTGGACTCGATTATCCAGGGGTAGGACCAGAGCACAGTTTCTTGAAAGACATT
GAGCGGGTGCGCTATGCGGCCGTCACGGATGACGAGGCACTCGATGCGTGTCTCGCCCTCAGCCGACAAGAAGGAATCAT
TCCTGCCTTAGAGTCTTCACACGCCCTTGCTTACGCAGAGACGCTCGCGAAGACGATGGGAGAAAACGATACACTGGTGA
TTTGTTTATCAGGGCGCGGAGACAAAGACGTCCATACAATCCGAGAGAAGGTGGCGACACGATGA

Upstream 100 bases:

>100_bases
AACCAGACGGCGTCGACGTCTCGAGCGGTGTCGAGACGGACGGTGTGAAAGATATCGAAAAAATTCGTGCGTTCATTCAA
CGCGCCAAGGAGGAACTATG

Downstream 100 bases:

>100_bases
AACTAGAGACAGCGATTCGACAGCGAGAAGGAGCGGCGTTCGTTCCGTATATCATGGCCGGTGACGGCGGGATGGACCGG
CTCATCCCGACCATCGTGGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MYAQPVNGKFGQYGGKYIPETLMQAVEELEVAYEEAKQDPEFQERFSSLLREYVGRETPLYYASNLSRRLGTNVYLKRED
LNHTGAHKINNTIGQALLAKRMGKQKVVAETGAGQHGVATATVCALLDLECTIFMGEVDVERQALNVFRMELLGAKVVPV
KSGSRTLKDAVNEALRYWVKHVDDTHYVMGSVLGPHPFPQMVRDFQSVIGTETRRQILEQTGRLPDAVVACVGGGSNAMG
MFYPFLNDESVALYGVEAAGSGIDTDKHAATLTKGEVGVLHGSLMYVLQDAAGQIEEAHSISAGLDYPGVGPEHSFLKDI
ERVRYAAVTDDEALDACLALSRQEGIIPALESSHALAYAETLAKTMGENDTLVICLSGRGDKDVHTIREKVATR

Sequences:

>Translated_394_residues
MYAQPVNGKFGQYGGKYIPETLMQAVEELEVAYEEAKQDPEFQERFSSLLREYVGRETPLYYASNLSRRLGTNVYLKRED
LNHTGAHKINNTIGQALLAKRMGKQKVVAETGAGQHGVATATVCALLDLECTIFMGEVDVERQALNVFRMELLGAKVVPV
KSGSRTLKDAVNEALRYWVKHVDDTHYVMGSVLGPHPFPQMVRDFQSVIGTETRRQILEQTGRLPDAVVACVGGGSNAMG
MFYPFLNDESVALYGVEAAGSGIDTDKHAATLTKGEVGVLHGSLMYVLQDAAGQIEEAHSISAGLDYPGVGPEHSFLKDI
ERVRYAAVTDDEALDACLALSRQEGIIPALESSHALAYAETLAKTMGENDTLVICLSGRGDKDVHTIREKVATR
>Mature_394_residues
MYAQPVNGKFGQYGGKYIPETLMQAVEELEVAYEEAKQDPEFQERFSSLLREYVGRETPLYYASNLSRRLGTNVYLKRED
LNHTGAHKINNTIGQALLAKRMGKQKVVAETGAGQHGVATATVCALLDLECTIFMGEVDVERQALNVFRMELLGAKVVPV
KSGSRTLKDAVNEALRYWVKHVDDTHYVMGSVLGPHPFPQMVRDFQSVIGTETRRQILEQTGRLPDAVVACVGGGSNAMG
MFYPFLNDESVALYGVEAAGSGIDTDKHAATLTKGEVGVLHGSLMYVLQDAAGQIEEAHSISAGLDYPGVGPEHSFLKDI
ERVRYAAVTDDEALDACLALSRQEGIIPALESSHALAYAETLAKTMGENDTLVICLSGRGDKDVHTIREKVATR

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=393, Percent_Identity=55.9796437659033, Blast_Score=447, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=58.22454308094, Blast_Score=456, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42982; Mature: 42982

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAQPVNGKFGQYGGKYIPETLMQAVEELEVAYEEAKQDPEFQERFSSLLREYVGRETPL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
YYASNLSRRLGTNVYLKREDLNHTGAHKINNTIGQALLAKRMGKQKVVAETGAGQHGVAT
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHH
ATVCALLDLECTIFMGEVDVERQALNVFRMELLGAKVVPVKSGSRTLKDAVNEALRYWVK
HHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHH
HVDDTHYVMGSVLGPHPFPQMVRDFQSVIGTETRRQILEQTGRLPDAVVACVGGGSNAMG
HCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHEEEECCCCCCCE
MFYPFLNDESVALYGVEAAGSGIDTDKHAATLTKGEVGVLHGSLMYVLQDAAGQIEEAHS
EEEECCCCCCEEEEEEHHCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISAGLDYPGVGPEHSFLKDIERVRYAAVTDDEALDACLALSRQEGIIPALESSHALAYAE
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
TLAKTMGENDTLVICLSGRGDKDVHTIREKVATR
HHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MYAQPVNGKFGQYGGKYIPETLMQAVEELEVAYEEAKQDPEFQERFSSLLREYVGRETPL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
YYASNLSRRLGTNVYLKREDLNHTGAHKINNTIGQALLAKRMGKQKVVAETGAGQHGVAT
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHH
ATVCALLDLECTIFMGEVDVERQALNVFRMELLGAKVVPVKSGSRTLKDAVNEALRYWVK
HHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHH
HVDDTHYVMGSVLGPHPFPQMVRDFQSVIGTETRRQILEQTGRLPDAVVACVGGGSNAMG
HCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHEEEECCCCCCCE
MFYPFLNDESVALYGVEAAGSGIDTDKHAATLTKGEVGVLHGSLMYVLQDAAGQIEEAHS
EEEECCCCCCEEEEEEHHCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISAGLDYPGVGPEHSFLKDIERVRYAAVTDDEALDACLALSRQEGIIPALESSHALAYAE
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
TLAKTMGENDTLVICLSGRGDKDVHTIREKVATR
HHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA