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The map label for this gene is speB [H]

Identifier: 229917108

GI number: 229917108

Start: 1353261

End: 1354142

Strand: Reverse

Name: speB [H]

Synonym: EAT1b_1382

Alternate gene names: 229917108

Gene position: 1354142-1353261 (Counterclockwise)

Preceding gene: 229917109

Following gene: 229917107

Centisome position: 45.14

GC content: 52.15

Gene sequence:

>882_bases
ATGATTAAGCGTTTCGATGAAGCCTACTCAGGTAAAGTGTTTATCGCCAGCCTCCCAGAGGTGACAGAGGCGAAGACGGT
TCTTTACGGGATGCCGATGGACTGGACAGTCAGCTTCCGTCCAGGTTCGCGTTTCGGTCCGAACCGGATTCGTGAAGTAT
CGATTGGACTCGAGGAATACAGCCCGTATTTAGACGGTGACTTGGCTGATGCCGCGGTGTACGATGCAGGCGATATCCCG
CTTCCATTCGGGAACGCACCGAAGTCGCTCGATATGATCGAGGCGTTCGTCAAAGATGTCGTCAAAGCAGGTAAGTTCCC
ACTCGGCATGGGTGGCGAACACCTTGTCACATGGCCGATCATCAAAGCGATGCACGACGTGTACGGCAACGACTTTGTTA
TCCTCCACTTGGATGCGCACACGGACCTTCGAGATGAGTATGAAGGCGAGCCGCTCTCACACTCGACTCCGCTCAAAAAA
GCGGCAAACTTGATCGGACCATCGAACTGCTATTCGTTCGGAATCCGTTCAGGGATGAAAGAAGAGTTTGAGTGGGCTCG
TGAAGTCGGCTACAACATGCATCAATTTGAAGTGATCGAACCACTCAAGCGTGTCTTACCGACACTCGCTGGTAAAAAAG
TATACGTCACCATCGACATCGACGTCCTCGACCCGTCAGCGGCACCAGGGACAGGGACGCAAGAAATCGGTGGCATCTCA
ACGAAAGAATTGCTCGAAGCGGTACATGCCATTGCAAACGCAGACCTCGACATCATCGGTGCAGACCTTGTCGAAGTGTC
ACCGGCATACGATCAGTCAGATATGACTGCCATCGCAGCAGCTAAGATTCTTCGTGAGATGATGATTGGATTCGTGAAGT
AA

Upstream 100 bases:

>100_bases
TATCAGCGGAGCGTTTCCATGACATCGAAACGAAGTACTATACGCCGAAGCTTCACAATGCAGCGTTCGTTCTTCCGAAA
TTCGTGGAGGACTTAACAAA

Downstream 100 bases:

>100_bases
ATGCGGAAAAAGGGTCAGCTGGAAATGGAACTGAGCGCTCGGATTACCCAATGGGAAAAAGAATATTTGGGTCGCGGGTC
ATTGACGTGTAAGGCAGACC

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MIKRFDEAYSGKVFIASLPEVTEAKTVLYGMPMDWTVSFRPGSRFGPNRIREVSIGLEEYSPYLDGDLADAAVYDAGDIP
LPFGNAPKSLDMIEAFVKDVVKAGKFPLGMGGEHLVTWPIIKAMHDVYGNDFVILHLDAHTDLRDEYEGEPLSHSTPLKK
AANLIGPSNCYSFGIRSGMKEEFEWAREVGYNMHQFEVIEPLKRVLPTLAGKKVYVTIDIDVLDPSAAPGTGTQEIGGIS
TKELLEAVHAIANADLDIIGADLVEVSPAYDQSDMTAIAAAKILREMMIGFVK

Sequences:

>Translated_293_residues
MIKRFDEAYSGKVFIASLPEVTEAKTVLYGMPMDWTVSFRPGSRFGPNRIREVSIGLEEYSPYLDGDLADAAVYDAGDIP
LPFGNAPKSLDMIEAFVKDVVKAGKFPLGMGGEHLVTWPIIKAMHDVYGNDFVILHLDAHTDLRDEYEGEPLSHSTPLKK
AANLIGPSNCYSFGIRSGMKEEFEWAREVGYNMHQFEVIEPLKRVLPTLAGKKVYVTIDIDVLDPSAAPGTGTQEIGGIS
TKELLEAVHAIANADLDIIGADLVEVSPAYDQSDMTAIAAAKILREMMIGFVK
>Mature_293_residues
MIKRFDEAYSGKVFIASLPEVTEAKTVLYGMPMDWTVSFRPGSRFGPNRIREVSIGLEEYSPYLDGDLADAAVYDAGDIP
LPFGNAPKSLDMIEAFVKDVVKAGKFPLGMGGEHLVTWPIIKAMHDVYGNDFVILHLDAHTDLRDEYEGEPLSHSTPLKK
AANLIGPSNCYSFGIRSGMKEEFEWAREVGYNMHQFEVIEPLKRVLPTLAGKKVYVTIDIDVLDPSAAPGTGTQEIGGIS
TKELLEAVHAIANADLDIIGADLVEVSPAYDQSDMTAIAAAKILREMMIGFVK

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=293, Percent_Identity=35.4948805460751, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1789306, Length=275, Percent_Identity=35.2727272727273, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 32098; Mature: 32098

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKRFDEAYSGKVFIASLPEVTEAKTVLYGMPMDWTVSFRPGSRFGPNRIREVSIGLEEY
CCCCCCHHHCCCEEEEECCCHHHHHHEEEECCCCEEEEECCCCCCCCCHHHEEECCHHHC
SPYLDGDLADAAVYDAGDIPLPFGNAPKSLDMIEAFVKDVVKAGKFPLGMGGEHLVTWPI
CCCCCCCHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHH
IKAMHDVYGNDFVILHLDAHTDLRDEYEGEPLSHSTPLKKAANLIGPSNCYSFGIRSGMK
HHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCH
EEFEWAREVGYNMHQFEVIEPLKRVLPTLAGKKVYVTIDIDVLDPSAAPGTGTQEIGGIS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCHHHCCCC
TKELLEAVHAIANADLDIIGADLVEVSPAYDQSDMTAIAAAKILREMMIGFVK
HHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKRFDEAYSGKVFIASLPEVTEAKTVLYGMPMDWTVSFRPGSRFGPNRIREVSIGLEEY
CCCCCCHHHCCCEEEEECCCHHHHHHEEEECCCCEEEEECCCCCCCCCHHHEEECCHHHC
SPYLDGDLADAAVYDAGDIPLPFGNAPKSLDMIEAFVKDVVKAGKFPLGMGGEHLVTWPI
CCCCCCCHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHH
IKAMHDVYGNDFVILHLDAHTDLRDEYEGEPLSHSTPLKKAANLIGPSNCYSFGIRSGMK
HHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCH
EEFEWAREVGYNMHQFEVIEPLKRVLPTLAGKKVYVTIDIDVLDPSAAPGTGTQEIGGIS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCHHHCCCC
TKELLEAVHAIANADLDIIGADLVEVSPAYDQSDMTAIAAAKILREMMIGFVK
HHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]