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The map label for this gene is mrkE [H]

Identifier: 229917026

GI number: 229917026

Start: 1277096

End: 1277875

Strand: Direct

Name: mrkE [H]

Synonym: EAT1b_1300

Alternate gene names: 229917026

Gene position: 1277096-1277875 (Clockwise)

Preceding gene: 229917025

Following gene: 229917028

Centisome position: 42.57

GC content: 41.67

Gene sequence:

>780_bases
ATGCGTACGATTTTAATTGAAGATGAACATCATATTTTAGGGATGATGGAGCGGATTGTAAAAGAAGAGCCGTCTCTTGA
GTGGGTTGGTTCGTTCCAAAGTCCGGTTCAAGCTCTCACTTTTATTCAAGAGCACCCGGTCGACCTCGTCTTTTTAGATA
TCGAAATGCCTGAAATGACGGGGCTCGAATTGGCGACCTATTTGCCAGAACGGACACAAGTCGTCTTCACGACCGCCCAT
CAACAGTATGCCGTTGAAGCGTTCAATTTGCATGCCACGCATTACTTGTTGAAGCCGATCACAGAGCAGATGATTCATAA
CGTCATTCCACGTATTGTGCAACGTTATGAATCCATTCAGCAAAAAAATGCACATCAATCGTGTCGCGTTCAGCTCCTTG
ATCGATTTTCGGTACGAACGCAAGATGGGAATCTTGTGAAGTGGCCAACACAAAAAACAGAGGAGTTATTTGCCTACTTA
GTTTTTCATCGTAAGCAGGTCATTAATAAGTGGGTGCTTGCCGAAACCCTTTACCCGGACATCGATGAACCACAACGCGC
CTTACACAACATATACAACACGATTTATCGATTGAAAAAGACGTTAGCTGAACATGAACTCGATATAACTGTTAATACAA
TAAATAATGGCTATTCGATCGAACTTGGTGATTCCTGTGCCTGTGATTATTACGATTGGCTTGATGCACCAAATCCTTCA
ATTTCTAAAACAGACTTAAAAAATCGTTTATTTGTTGATAAAGACTATACATGGCATTGA

Upstream 100 bases:

>100_bases
GAACACCTCCCTGGTGCAACGTTTGACTTAGCTTCCACTTTGAAAAAAGGCACCACCATTCACCTGCGTTTACCAAAACA
GGAAAGGACGAATCATTTAG

Downstream 100 bases:

>100_bases
AAAAGGCATCTCACAATTGAAGTGAGATGCCTTCTTTTTATTGTATCCATCGAACGTTCTCTATTAGCGCCCAGTAAACC
CTCCGTCAACGTGAAGATGT

Product: response regulator receiver and SARP domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRTILIEDEHHILGMMERIVKEEPSLEWVGSFQSPVQALTFIQEHPVDLVFLDIEMPEMTGLELATYLPERTQVVFTTAH
QQYAVEAFNLHATHYLLKPITEQMIHNVIPRIVQRYESIQQKNAHQSCRVQLLDRFSVRTQDGNLVKWPTQKTEELFAYL
VFHRKQVINKWVLAETLYPDIDEPQRALHNIYNTIYRLKKTLAEHELDITVNTINNGYSIELGDSCACDYYDWLDAPNPS
ISKTDLKNRLFVDKDYTWH

Sequences:

>Translated_259_residues
MRTILIEDEHHILGMMERIVKEEPSLEWVGSFQSPVQALTFIQEHPVDLVFLDIEMPEMTGLELATYLPERTQVVFTTAH
QQYAVEAFNLHATHYLLKPITEQMIHNVIPRIVQRYESIQQKNAHQSCRVQLLDRFSVRTQDGNLVKWPTQKTEELFAYL
VFHRKQVINKWVLAETLYPDIDEPQRALHNIYNTIYRLKKTLAEHELDITVNTINNGYSIELGDSCACDYYDWLDAPNPS
ISKTDLKNRLFVDKDYTWH
>Mature_259_residues
MRTILIEDEHHILGMMERIVKEEPSLEWVGSFQSPVQALTFIQEHPVDLVFLDIEMPEMTGLELATYLPERTQVVFTTAH
QQYAVEAFNLHATHYLLKPITEQMIHNVIPRIVQRYESIQQKNAHQSCRVQLLDRFSVRTQDGNLVKWPTQKTEELFAYL
VFHRKQVINKWVLAETLYPDIDEPQRALHNIYNTIYRLKKTLAEHELDITVNTINNGYSIELGDSCACDYYDWLDAPNPS
ISKTDLKNRLFVDKDYTWH

Specific function: May be involved in the regulation of fimbrial expression [H]

COG id: COG3947

COG function: function code T; Response regulator containing CheY-like receiver and SARP domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=115, Percent_Identity=35.6521739130435, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082052, Length=116, Percent_Identity=34.4827586206897, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30457; Mature: 30457

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTILIEDEHHILGMMERIVKEEPSLEWVGSFQSPVQALTFIQEHPVDLVFLDIEMPEMT
CCEEEECCCHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
GLELATYLPERTQVVFTTAHQQYAVEAFNLHATHYLLKPITEQMIHNVIPRIVQRYESIQ
CHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKNAHQSCRVQLLDRFSVRTQDGNLVKWPTQKTEELFAYLVFHRKQVINKWVLAETLYPD
HHCCHHHHHHHHHHHHHEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IDEPQRALHNIYNTIYRLKKTLAEHELDITVNTINNGYSIELGDSCACDYYDWLDAPNPS
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCCCHHHCCCCCCC
ISKTDLKNRLFVDKDYTWH
CCHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MRTILIEDEHHILGMMERIVKEEPSLEWVGSFQSPVQALTFIQEHPVDLVFLDIEMPEMT
CCEEEECCCHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHCCCEEEEEEEECCCCC
GLELATYLPERTQVVFTTAHQQYAVEAFNLHATHYLLKPITEQMIHNVIPRIVQRYESIQ
CHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKNAHQSCRVQLLDRFSVRTQDGNLVKWPTQKTEELFAYLVFHRKQVINKWVLAETLYPD
HHCCHHHHHHHHHHHHHEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IDEPQRALHNIYNTIYRLKKTLAEHELDITVNTINNGYSIELGDSCACDYYDWLDAPNPS
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCCCHHHCCCCCCC
ISKTDLKNRLFVDKDYTWH
CCHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1670938 [H]