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The map label for this gene is ypdA [H]

Identifier: 229917025

GI number: 229917025

Start: 1275334

End: 1277115

Strand: Direct

Name: ypdA [H]

Synonym: EAT1b_1299

Alternate gene names: 229917025

Gene position: 1275334-1277115 (Clockwise)

Preceding gene: 229917020

Following gene: 229917026

Centisome position: 42.51

GC content: 43.38

Gene sequence:

>1782_bases
ATGACGCGTAATCGAATGACGTTTATCCTCATCCTTGTGATGTTGGTTGGCGTCAGTCTCACTTTATTGATTCGACATCA
GTCAATCAATCCGATCGTCACCGTTAACAAGGGCGAAGCTTCTCTTCTCTCTTCTACTGTCGACGAAGAGATTTTGCGAC
TAGACGGCTCATGGCGCTATGAGTCAGGAATTGTCACCCAAGTTGATCGCCGCTCCTATCGAACCATTCCATTTACGACG
CCTTATCGGGCATCCACATATGAACTCGATCTCACGTTGCCGAACGGTACGTATGCCTTGCTCATTCCAAAGTCCCTCTC
CTCTTCTACGATATTGATAGATGGGAAAATCGTTGAAACGATACAATTTGGAAACAATCGTCTCGTCGAGCAGCCGTCTC
TGCTCTTGCTCGATGATGAGACAAAACAATTCCGACTGACGATTCAACATGAACGACAGGCAGGTAATTCCGCACCCATC
GAAGAAAGTATATTGGTCGGACCGTTACATGCCATCATGACCACTCAAAATGCTTATGCCGGTTACGAATTTTTCATGTT
GCTCATTTCACTTTTGATTGCCATGTTCTATGCCATTGTCTATCTCTTTCACCGAAATGAACGGTTGTATGGTTTCGGGA
CAGCCTTCTTTTTGTTGACGAGTTTTTCAATCATGTCCCGAGATGGCATGTGGATCTCGGGTAGTAATAAGTTGACGTTA
AGTTTAGCCTTACTGAGCATCATCATGCTGATCGAGTTTTCACGATGCTTGGAACGTGTGTCATTTGACCGTTTTTTGGC
CATTTCGAGATACCCACTGTATGGATTGACTGTACTAGCCATCTTCCTGCCCTCTTCCGTTTACGAGGTGTACGAATATT
TTGTATGGATTATCGTTTTATTTATCACGTTCTTCTGGATCGGATTGAATATTGGATGGCTCCTTGAAAAGTACAAGACA
GGTAATCCACTCGAGTTACTAACTTTCACGCTCGCCCAACTCGTCGGGTATATCGGAATCATGACGTCGACGTTCATCGT
CTCGCCTAATCAGCAATTGTACTCCAATACGTTTACCATCATCTATTTCCTATTGATGTTTTTACTTCTACCGATTCATT
TGTCTACCGACAAAGGGAAGAAACAACAAGTTGAAGCGTTGGCTTCGCAGCACGAGATGTCCTTCTTTAACGCGCAAATC
AAACCTCACTTCCTTTACAATACGTTTGGAAATGTGATTGCACTCTGTTATACGTCACCACCTGAAGCGGCTCGTCTACT
TAGTCACTTGAGCACATACGTCCGCTATATTTTTGAGAATGGTCGAGCCGAAAATGAGATTTCCATTCGTCAAGAAGTCG
ATATGATCGACTCTTACCTCGCCATTGAACAGACACGGTTTCGTGATTCGTTCTACGTCAAGAAAGAGATTAATGAGTCT
CTTTTGGACTGTTCAATTCCACCCTTATTGATTCAACCACTCGTTGAAAATGCCGTGCGACATGGTCTCTATCGACACCC
AGGACAAAAGCGATTGACACTTTCTATCCAGGAACGAAATGGAATGATCGAGATTTTTGTTCAAGATACAGGGAGTGGTT
TTGATCCAAACGTATCAAACAAAACATCTGGGATTGGGATTTGCAATATTAAAAGTCGAATCGAACACCTCCCTGGTGCA
ACGTTTGACTTAGCTTCCACTTTGAAAAAAGGCACCACCATTCACCTGCGTTTACCAAAACAGGAAAGGACGAATCATTT
AGATGCGTACGATTTTAATTGA

Upstream 100 bases:

>100_bases
ATGATGAGACGGAGAGTCACTTCAAAAATTCATTCACCTATTAGGAAGAATAACGGAATGACCTCACAAGAAACTCACAA
AGATTGAAGGGAATGTGTTC

Downstream 100 bases:

>100_bases
AGATGAACATCATATTTTAGGGATGATGGAGCGGATTGTAAAAGAAGAGCCGTCTCTTGAGTGGGTTGGTTCGTTCCAAA
GTCCGGTTCAAGCTCTCACT

Product: signal transduction histidine kinase, LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MTRNRMTFILILVMLVGVSLTLLIRHQSINPIVTVNKGEASLLSSTVDEEILRLDGSWRYESGIVTQVDRRSYRTIPFTT
PYRASTYELDLTLPNGTYALLIPKSLSSSTILIDGKIVETIQFGNNRLVEQPSLLLLDDETKQFRLTIQHERQAGNSAPI
EESILVGPLHAIMTTQNAYAGYEFFMLLISLLIAMFYAIVYLFHRNERLYGFGTAFFLLTSFSIMSRDGMWISGSNKLTL
SLALLSIIMLIEFSRCLERVSFDRFLAISRYPLYGLTVLAIFLPSSVYEVYEYFVWIIVLFITFFWIGLNIGWLLEKYKT
GNPLELLTFTLAQLVGYIGIMTSTFIVSPNQQLYSNTFTIIYFLLMFLLLPIHLSTDKGKKQQVEALASQHEMSFFNAQI
KPHFLYNTFGNVIALCYTSPPEAARLLSHLSTYVRYIFENGRAENEISIRQEVDMIDSYLAIEQTRFRDSFYVKKEINES
LLDCSIPPLLIQPLVENAVRHGLYRHPGQKRLTLSIQERNGMIEIFVQDTGSGFDPNVSNKTSGIGICNIKSRIEHLPGA
TFDLASTLKKGTTIHLRLPKQERTNHLDAYDFN

Sequences:

>Translated_593_residues
MTRNRMTFILILVMLVGVSLTLLIRHQSINPIVTVNKGEASLLSSTVDEEILRLDGSWRYESGIVTQVDRRSYRTIPFTT
PYRASTYELDLTLPNGTYALLIPKSLSSSTILIDGKIVETIQFGNNRLVEQPSLLLLDDETKQFRLTIQHERQAGNSAPI
EESILVGPLHAIMTTQNAYAGYEFFMLLISLLIAMFYAIVYLFHRNERLYGFGTAFFLLTSFSIMSRDGMWISGSNKLTL
SLALLSIIMLIEFSRCLERVSFDRFLAISRYPLYGLTVLAIFLPSSVYEVYEYFVWIIVLFITFFWIGLNIGWLLEKYKT
GNPLELLTFTLAQLVGYIGIMTSTFIVSPNQQLYSNTFTIIYFLLMFLLLPIHLSTDKGKKQQVEALASQHEMSFFNAQI
KPHFLYNTFGNVIALCYTSPPEAARLLSHLSTYVRYIFENGRAENEISIRQEVDMIDSYLAIEQTRFRDSFYVKKEINES
LLDCSIPPLLIQPLVENAVRHGLYRHPGQKRLTLSIQERNGMIEIFVQDTGSGFDPNVSNKTSGIGICNIKSRIEHLPGA
TFDLASTLKKGTTIHLRLPKQERTNHLDAYDFN
>Mature_592_residues
TRNRMTFILILVMLVGVSLTLLIRHQSINPIVTVNKGEASLLSSTVDEEILRLDGSWRYESGIVTQVDRRSYRTIPFTTP
YRASTYELDLTLPNGTYALLIPKSLSSSTILIDGKIVETIQFGNNRLVEQPSLLLLDDETKQFRLTIQHERQAGNSAPIE
ESILVGPLHAIMTTQNAYAGYEFFMLLISLLIAMFYAIVYLFHRNERLYGFGTAFFLLTSFSIMSRDGMWISGSNKLTLS
LALLSIIMLIEFSRCLERVSFDRFLAISRYPLYGLTVLAIFLPSSVYEVYEYFVWIIVLFITFFWIGLNIGWLLEKYKTG
NPLELLTFTLAQLVGYIGIMTSTFIVSPNQQLYSNTFTIIYFLLMFLLLPIHLSTDKGKKQQVEALASQHEMSFFNAQIK
PHFLYNTFGNVIALCYTSPPEAARLLSHLSTYVRYIFENGRAENEISIRQEVDMIDSYLAIEQTRFRDSFYVKKEINESL
LDCSIPPLLIQPLVENAVRHGLYRHPGQKRLTLSIQERNGMIEIFVQDTGSGFDPNVSNKTSGIGICNIKSRIEHLPGAT
FDLASTLKKGTTIHLRLPKQERTNHLDAYDFN

Specific function: Unknown

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788723, Length=209, Percent_Identity=35.8851674641148, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788446, Length=203, Percent_Identity=27.0935960591133, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: 2.7.3.-

Molecular weight: Translated: 67680; Mature: 67548

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNRMTFILILVMLVGVSLTLLIRHQSINPIVTVNKGEASLLSSTVDEEILRLDGSWRY
CCCCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEE
ESGIVTQVDRRSYRTIPFTTPYRASTYELDLTLPNGTYALLIPKSLSSSTILIDGKIVET
CCCCEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEEECEEEEE
IQFGNNRLVEQPSLLLLDDETKQFRLTIQHERQAGNSAPIEESILVGPLHAIMTTQNAYA
EECCCCEEECCCCEEEEECCCCEEEEEEEEHHCCCCCCCCCCHHHHCCHHHHHCCCCCCC
GYEFFMLLISLLIAMFYAIVYLFHRNERLYGFGTAFFLLTSFSIMSRDGMWISGSNKLTL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCEEH
SLALLSIIMLIEFSRCLERVSFDRFLAISRYPLYGLTVLAIFLPSSVYEVYEYFVWIIVL
HHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITFFWIGLNIGWLLEKYKTGNPLELLTFTLAQLVGYIGIMTSTFIVSPNQQLYSNTFTI
HHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHH
IYFLLMFLLLPIHLSTDKGKKQQVEALASQHEMSFFNAQIKPHFLYNTFGNVIALCYTSP
HHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCEEEEEECCC
PEAARLLSHLSTYVRYIFENGRAENEISIRQEVDMIDSYLAIEQTRFRDSFYVKKEINES
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
LLDCSIPPLLIQPLVENAVRHGLYRHPGQKRLTLSIQERNGMIEIFVQDTGSGFDPNVSN
HHHCCCCHHHHHHHHHHHHHCCHHCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCC
KTSGIGICNIKSRIEHLPGATFDLASTLKKGTTIHLRLPKQERTNHLDAYDFN
CCCCEEEEEHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCHHCCCCCCCCCCC
>Mature Secondary Structure 
TRNRMTFILILVMLVGVSLTLLIRHQSINPIVTVNKGEASLLSSTVDEEILRLDGSWRY
CCCHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEE
ESGIVTQVDRRSYRTIPFTTPYRASTYELDLTLPNGTYALLIPKSLSSSTILIDGKIVET
CCCCEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCEEEEECEEEEE
IQFGNNRLVEQPSLLLLDDETKQFRLTIQHERQAGNSAPIEESILVGPLHAIMTTQNAYA
EECCCCEEECCCCEEEEECCCCEEEEEEEEHHCCCCCCCCCCHHHHCCHHHHHCCCCCCC
GYEFFMLLISLLIAMFYAIVYLFHRNERLYGFGTAFFLLTSFSIMSRDGMWISGSNKLTL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCEEH
SLALLSIIMLIEFSRCLERVSFDRFLAISRYPLYGLTVLAIFLPSSVYEVYEYFVWIIVL
HHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITFFWIGLNIGWLLEKYKTGNPLELLTFTLAQLVGYIGIMTSTFIVSPNQQLYSNTFTI
HHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHH
IYFLLMFLLLPIHLSTDKGKKQQVEALASQHEMSFFNAQIKPHFLYNTFGNVIALCYTSP
HHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCEEEEEECCC
PEAARLLSHLSTYVRYIFENGRAENEISIRQEVDMIDSYLAIEQTRFRDSFYVKKEINES
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
LLDCSIPPLLIQPLVENAVRHGLYRHPGQKRLTLSIQERNGMIEIFVQDTGSGFDPNVSN
HHHCCCCHHHHHHHHHHHHHCCHHCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCC
KTSGIGICNIKSRIEHLPGATFDLASTLKKGTTIHLRLPKQERTNHLDAYDFN
CCCCEEEEEHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]