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The map label for this gene is ptsG [H]

Identifier: 229917013

GI number: 229917013

Start: 1263668

End: 1265206

Strand: Reverse

Name: ptsG [H]

Synonym: EAT1b_1287

Alternate gene names: 229917013

Gene position: 1265206-1263668 (Counterclockwise)

Preceding gene: 229917014

Following gene: 229917012

Centisome position: 42.18

GC content: 49.58

Gene sequence:

>1539_bases
ATGTCACGTCTCTTTGAACGAGCGCAACAATTCGGGAAATCGTTCATGTTGCCGATTGCTGTCTTACCGGCCGCTGGACT
ACTGTTAGGAATTGGGGGCGCCTTGTCTAACCCGAATACGGTGCAAGCGTACCCGTTCCTCGACATCGACTGGTTGCAAC
ATCTATTCACCATTATGGCGGCTGCCGGTTCAATCGTATTCGCGAACTTGGCTGTGTTGTTTGCCATCGGTGTCGCTGTC
GGACTCGCGAAGTCTGATAAAGGAACGGCCGGATTGGCGGCGATGCTTGGGTATTTGATTATGAATGCGACCATCAACGC
AATGCTTCAGATTACTGGAGAGTTGATGGAAACGAACTTAGCGAGTGCCGGTCAAGGGATGGCGCTCGGAATTCAAACGC
TTGAAACTGGTGTGTTCGGTGGGATCTTGATTGGGATTGTCACGGCGCTCTTGCATAACCGCTACAACAAGCAAGTGCTT
CCACAGTTCCTCGGGTTCTTCAGCGGATCACGTTTTGTCCCAATCATCACGTCATTCGTTGCGATTGGTGTAGGGATTGG
GCTCTACTTCATCTGGCCGACGGTGCAGAACGGGATTTTCTCGTTAGGTGGTCTCGTTGAAAAAACAGGATATATCGGAA
CATTCATTTATGGGTTCGTCCTTCGGATGCTTGGACCATTTGGGTTGCACCATATCTTCTACATTCCGTTTTGGACCACT
GGGCTCGGGGGCTCGATGGTCATTGACGGATCATTGATCGAAGGAACGCAAAAGATTTTCTTCGCGCAGTTGGCTGACCC
GAATACGACACAATTCTATGAAGGAACAGCACGATTTATGTCGGGTCGATTCATCACGATGATGTTTGGTCTTCTCGGTG
CGGCGCTTGCCATGTATCACTGTGCAAAGCCGGAGCAAAAGAAAGTCGTGTTCGGTCTCTTGTTCTCGGCAGCACTCACC
TCATTCTTGACGGGAATCACAGAGCCACTCGAATTCGCATTTTTGTTTGTCGCGCCGGTCCTCTATCTAGTACATGCTAT
CTTTGATGGACTTGCTTTTATGATGGCTCACATCTTTGAGATTACGATTGGTCAAACATTCTCTGGTGGGTTCATTGATT
TTATCTTATTCGGGGTCTTACAAGGGAATGACAAGACGAACTGGATGCTCGTACCGGTCATCGGTGCCTTCTGGTTCTTG
CTCTACTACGTAACGTTCCGTTTCCTCATCACAAAGTTCAATTTCATGACACCTGGACGATCGGATGAGACAGTGAAAAC
AGCAGACGTTGCGGCGTCGGATCGTACGTCAGCCATCATTGCGGCACTAGGTGGCGACGACAATATTGAGACGGTCGACT
GCTGCGCGACACGCCTCCGCGTCACCGTCAACGACAATCAACATGTCCGTGAAGACTTGTTGAAAGAGACGGGCGCTCAC
GGGGTGGTTCAAAAAGGGAATGGAATTCAAGTAATCTACGGTCCTTCTGTTACAATTATTAAGAATGAAGTCCAAGAGGC
GTTAGGCCGGGGCGAATAA

Upstream 100 bases:

>100_bases
GAGGTCACTCTTTTTAAAATCTTTTTTACCGTAAACGCTTGCATAAAAATATTTTTCATATTATGATTCAGGTGAAAATG
ATTTTAAGGAGGATTTATTC

Downstream 100 bases:

>100_bases
CGAATGTGTTGGAGGGAAGAACCGTGTGGGAGCAAATAAAACACGTGTATTCAGAAATGACGGGCAGTGAGAAAAAGATT
GCGGATTATCTGATGGCGAA

Product: PTS system, glucose-like IIB subunint

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSRLFERAQQFGKSFMLPIAVLPAAGLLLGIGGALSNPNTVQAYPFLDIDWLQHLFTIMAAAGSIVFANLAVLFAIGVAV
GLAKSDKGTAGLAAMLGYLIMNATINAMLQITGELMETNLASAGQGMALGIQTLETGVFGGILIGIVTALLHNRYNKQVL
PQFLGFFSGSRFVPIITSFVAIGVGIGLYFIWPTVQNGIFSLGGLVEKTGYIGTFIYGFVLRMLGPFGLHHIFYIPFWTT
GLGGSMVIDGSLIEGTQKIFFAQLADPNTTQFYEGTARFMSGRFITMMFGLLGAALAMYHCAKPEQKKVVFGLLFSAALT
SFLTGITEPLEFAFLFVAPVLYLVHAIFDGLAFMMAHIFEITIGQTFSGGFIDFILFGVLQGNDKTNWMLVPVIGAFWFL
LYYVTFRFLITKFNFMTPGRSDETVKTADVAASDRTSAIIAALGGDDNIETVDCCATRLRVTVNDNQHVREDLLKETGAH
GVVQKGNGIQVIYGPSVTIIKNEVQEALGRGE

Sequences:

>Translated_512_residues
MSRLFERAQQFGKSFMLPIAVLPAAGLLLGIGGALSNPNTVQAYPFLDIDWLQHLFTIMAAAGSIVFANLAVLFAIGVAV
GLAKSDKGTAGLAAMLGYLIMNATINAMLQITGELMETNLASAGQGMALGIQTLETGVFGGILIGIVTALLHNRYNKQVL
PQFLGFFSGSRFVPIITSFVAIGVGIGLYFIWPTVQNGIFSLGGLVEKTGYIGTFIYGFVLRMLGPFGLHHIFYIPFWTT
GLGGSMVIDGSLIEGTQKIFFAQLADPNTTQFYEGTARFMSGRFITMMFGLLGAALAMYHCAKPEQKKVVFGLLFSAALT
SFLTGITEPLEFAFLFVAPVLYLVHAIFDGLAFMMAHIFEITIGQTFSGGFIDFILFGVLQGNDKTNWMLVPVIGAFWFL
LYYVTFRFLITKFNFMTPGRSDETVKTADVAASDRTSAIIAALGGDDNIETVDCCATRLRVTVNDNQHVREDLLKETGAH
GVVQKGNGIQVIYGPSVTIIKNEVQEALGRGE
>Mature_511_residues
SRLFERAQQFGKSFMLPIAVLPAAGLLLGIGGALSNPNTVQAYPFLDIDWLQHLFTIMAAAGSIVFANLAVLFAIGVAVG
LAKSDKGTAGLAAMLGYLIMNATINAMLQITGELMETNLASAGQGMALGIQTLETGVFGGILIGIVTALLHNRYNKQVLP
QFLGFFSGSRFVPIITSFVAIGVGIGLYFIWPTVQNGIFSLGGLVEKTGYIGTFIYGFVLRMLGPFGLHHIFYIPFWTTG
LGGSMVIDGSLIEGTQKIFFAQLADPNTTQFYEGTARFMSGRFITMMFGLLGAALAMYHCAKPEQKKVVFGLLFSAALTS
FLTGITEPLEFAFLFVAPVLYLVHAIFDGLAFMMAHIFEITIGQTFSGGFIDFILFGVLQGNDKTNWMLVPVIGAFWFLL
YYVTFRFLITKFNFMTPGRSDETVKTADVAASDRTSAIIAALGGDDNIETVDCCATRLRVTVNDNQHVREDLLKETGAHG
VVQKGNGIQVIYGPSVTIIKNEVQEALGRGE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=513, Percent_Identity=43.0799220272904, Blast_Score=396, Evalue=1e-111,
Organism=Escherichia coli, GI1787343, Length=504, Percent_Identity=41.6666666666667, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1786894, Length=513, Percent_Identity=37.8167641325536, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 55360; Mature: 55228

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLFERAQQFGKSFMLPIAVLPAAGLLLGIGGALSNPNTVQAYPFLDIDWLQHLFTIMA
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
AAGSIVFANLAVLFAIGVAVGLAKSDKGTAGLAAMLGYLIMNATINAMLQITGELMETNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAGQGMALGIQTLETGVFGGILIGIVTALLHNRYNKQVLPQFLGFFSGSRFVPIITSFV
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH
AIGVGIGLYFIWPTVQNGIFSLGGLVEKTGYIGTFIYGFVLRMLGPFGLHHIFYIPFWTT
HHHHHHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHEEEEEEEEC
GLGGSMVIDGSLIEGTQKIFFAQLADPNTTQFYEGTARFMSGRFITMMFGLLGAALAMYH
CCCCCEEECCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
CAKPEQKKVVFGLLFSAALTSFLTGITEPLEFAFLFVAPVLYLVHAIFDGLAFMMAHIFE
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITIGQTFSGGFIDFILFGVLQGNDKTNWMLVPVIGAFWFLLYYVTFRFLITKFNFMTPGR
HHCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDETVKTADVAASDRTSAIIAALGGDDNIETVDCCATRLRVTVNDNQHVREDLLKETGAH
CCCCEEHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHEEEEECCCHHHHHHHHHHCCCC
GVVQKGNGIQVIYGPSVTIIKNEVQEALGRGE
CEEECCCCEEEEECCCEEEEHHHHHHHHCCCC
>Mature Secondary Structure 
SRLFERAQQFGKSFMLPIAVLPAAGLLLGIGGALSNPNTVQAYPFLDIDWLQHLFTIMA
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHH
AAGSIVFANLAVLFAIGVAVGLAKSDKGTAGLAAMLGYLIMNATINAMLQITGELMETNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAGQGMALGIQTLETGVFGGILIGIVTALLHNRYNKQVLPQFLGFFSGSRFVPIITSFV
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH
AIGVGIGLYFIWPTVQNGIFSLGGLVEKTGYIGTFIYGFVLRMLGPFGLHHIFYIPFWTT
HHHHHHHHHEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHEEEEEEEEC
GLGGSMVIDGSLIEGTQKIFFAQLADPNTTQFYEGTARFMSGRFITMMFGLLGAALAMYH
CCCCCEEECCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
CAKPEQKKVVFGLLFSAALTSFLTGITEPLEFAFLFVAPVLYLVHAIFDGLAFMMAHIFE
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITIGQTFSGGFIDFILFGVLQGNDKTNWMLVPVIGAFWFLLYYVTFRFLITKFNFMTPGR
HHCCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SDETVKTADVAASDRTSAIIAALGGDDNIETVDCCATRLRVTVNDNQHVREDLLKETGAH
CCCCEEHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHEEEEECCCHHHHHHHHHHCCCC
GVVQKGNGIQVIYGPSVTIIKNEVQEALGRGE
CEEECCCCEEEEECCCEEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]