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The map label for this gene is mcpA [H]

Identifier: 229916971

GI number: 229916971

Start: 1219921

End: 1221456

Strand: Direct

Name: mcpA [H]

Synonym: EAT1b_1245

Alternate gene names: 229916971

Gene position: 1219921-1221456 (Clockwise)

Preceding gene: 229916970

Following gene: 229916979

Centisome position: 40.67

GC content: 49.48

Gene sequence:

>1536_bases
ATGATGAGTTTGATCAAAAGAAATCAGTTGATGTTGTTGACGACGTTATTGATTGTGATGACGTCGATTGTTGTCCATTT
GCTACATCGTTTCACGGATTTTGCCTATGCATATACGATCCTACGAAACGGTGCGGACGATTACGTATACTCCGGTGTGA
CGTGGGTCTTGTTCGCCCTCCCAATCGTCTTCTTCGGGATGATGGTCGTCACCTCGAAGCGAGAATCTCTAGCTTTTTCC
TATTGGATGATGCTAACACTCACCTTCGCAAGCATCTCGACCGTCGCTGGAGGACAAGGACTCGTTGAGTATCACTTCTC
GATTTTTGTCGTCTTGGCGATTTTGTCGTTCATGCGTCGAATCGATTTGATTTTGTATAGTGCGGGGATCTTTGCTGTGC
AACATCTGGTTGGATACTTTTTGATTCCTGAGATGATTTGTGGGACGAGCGACTATCCGTTCAGTTTACTACTCGTCCAT
GCCGTATATTTGATTCTTCTCAGCGTCGTGCTTGTCGCGCAAATCCACTTCCGTAATAAAGAGACGGAACGTGTCGAGGC
ACAGGAGCAAGAAACGCGACAGTTGTTACAACAAGCGATTCATGATGTCAGCGTGCTCGTTCAATCTTTGAACAGTCACG
CCGAAGAGCTTGAATCCGCTGCTAACCAGTCTCTCGAATCAGGTGAGCAAATCGCTGTCACGGTCGACCCGATTGTCGCA
CATGCTTCATCCCAACAGGAATCCATGGTGCAAGGGGCAGATGAAATTCACTCAATCCGGTCTTTGACGGCGCTCATTCA
AGAACGAATGGCCCAGACGGCCGCAGCGTCCTCGCGTATCGCCAAAGATGCCCTTGCCGGGAACAAAGACATGCGACTGA
TGGAAGCAAAAGTACAAGAAATCATCACCGAGTCGGAACAACTCGACCGGATTGTCGCGACGATGTCGAATCGTTCAACC
GAAATCCAAGGAATCTTGCAACAAGTCGGTTCCATCAGTGAACAGACGAATATGCTCGCCTTGAACGCATCCATTGAAGC
GGCTCGTGCCGGTGAGGCTGGACGAGGATTCGCCGTCGTCGCCTCAGAAGTCGGGAAACTTGCTGTCCAATCGCGCGAAT
ATGCATCCGAGATGACCCGAGTCCTCGGTGGATTGATGGAAGATACGACTGTCGTATCCAAATCAGCGCATCTTTTCAAA
CAAGCGACCGAAAACTGTCAAACGGTCACGAACGATGTGACGGCTGTGTTTGATCGTCTAACGGAAGATGTTTCAGAAAT
CGACGAACAAATCGCTTCGATTCAAGAGACACGCCAACGGGTCACGACACAGATGGAAGCACTTGAAACACGACTTGAGT
CGACGAAATATGCGGCGAATGAACTCCAACAACAGATTCACCATGTTGCCGCAGCAACGGAAGAGCAAGTCGCCATTCAA
AAAGAACTCAGTTCGATGTCGGACCGTCTCGCTCTGACCGCGAATTCGCTTGAAGACGTGACGACTCAACTCGAGGATCA
CGCCACTCGTGCCTAA

Upstream 100 bases:

>100_bases
TCCTTTTTTTGTTCCAAATGTGCAATCTATATTAACTTCCGTCAACTTCATCCGATATGTATAGAGCTACAACAAATGAA
CACGAGAATGTGAGGAAAGA

Downstream 100 bases:

>100_bases
CACAAATGCCCCCGACCAAGTGGTCGAGGGCATTTTACTTATCGGTCGAGCAATTGACGAATTCCTTCTTGAAGAGGTGT
GACCGGGCGTCCGAGAACCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: H1 [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MMSLIKRNQLMLLTTLLIVMTSIVVHLLHRFTDFAYAYTILRNGADDYVYSGVTWVLFALPIVFFGMMVVTSKRESLAFS
YWMMLTLTFASISTVAGGQGLVEYHFSIFVVLAILSFMRRIDLILYSAGIFAVQHLVGYFLIPEMICGTSDYPFSLLLVH
AVYLILLSVVLVAQIHFRNKETERVEAQEQETRQLLQQAIHDVSVLVQSLNSHAEELESAANQSLESGEQIAVTVDPIVA
HASSQQESMVQGADEIHSIRSLTALIQERMAQTAAASSRIAKDALAGNKDMRLMEAKVQEIITESEQLDRIVATMSNRST
EIQGILQQVGSISEQTNMLALNASIEAARAGEAGRGFAVVASEVGKLAVQSREYASEMTRVLGGLMEDTTVVSKSAHLFK
QATENCQTVTNDVTAVFDRLTEDVSEIDEQIASIQETRQRVTTQMEALETRLESTKYAANELQQQIHHVAAATEEQVAIQ
KELSSMSDRLALTANSLEDVTTQLEDHATRA

Sequences:

>Translated_511_residues
MMSLIKRNQLMLLTTLLIVMTSIVVHLLHRFTDFAYAYTILRNGADDYVYSGVTWVLFALPIVFFGMMVVTSKRESLAFS
YWMMLTLTFASISTVAGGQGLVEYHFSIFVVLAILSFMRRIDLILYSAGIFAVQHLVGYFLIPEMICGTSDYPFSLLLVH
AVYLILLSVVLVAQIHFRNKETERVEAQEQETRQLLQQAIHDVSVLVQSLNSHAEELESAANQSLESGEQIAVTVDPIVA
HASSQQESMVQGADEIHSIRSLTALIQERMAQTAAASSRIAKDALAGNKDMRLMEAKVQEIITESEQLDRIVATMSNRST
EIQGILQQVGSISEQTNMLALNASIEAARAGEAGRGFAVVASEVGKLAVQSREYASEMTRVLGGLMEDTTVVSKSAHLFK
QATENCQTVTNDVTAVFDRLTEDVSEIDEQIASIQETRQRVTTQMEALETRLESTKYAANELQQQIHHVAAATEEQVAIQ
KELSSMSDRLALTANSLEDVTTQLEDHATRA
>Mature_511_residues
MMSLIKRNQLMLLTTLLIVMTSIVVHLLHRFTDFAYAYTILRNGADDYVYSGVTWVLFALPIVFFGMMVVTSKRESLAFS
YWMMLTLTFASISTVAGGQGLVEYHFSIFVVLAILSFMRRIDLILYSAGIFAVQHLVGYFLIPEMICGTSDYPFSLLLVH
AVYLILLSVVLVAQIHFRNKETERVEAQEQETRQLLQQAIHDVSVLVQSLNSHAEELESAANQSLESGEQIAVTVDPIVA
HASSQQESMVQGADEIHSIRSLTALIQERMAQTAAASSRIAKDALAGNKDMRLMEAKVQEIITESEQLDRIVATMSNRST
EIQGILQQVGSISEQTNMLALNASIEAARAGEAGRGFAVVASEVGKLAVQSREYASEMTRVLGGLMEDTTVVSKSAHLFK
QATENCQTVTNDVTAVFDRLTEDVSEIDEQIASIQETRQRVTTQMEALETRLESTKYAANELQQQIHHVAAATEEQVAIQ
KELSSMSDRLALTANSLEDVTTQLEDHATRA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=133, Percent_Identity=42.1052631578947, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788194, Length=223, Percent_Identity=33.1838565022422, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367378, Length=133, Percent_Identity=42.1052631578947, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787690, Length=169, Percent_Identity=33.7278106508876, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789453, Length=196, Percent_Identity=29.0816326530612, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56523; Mature: 56523

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLIKRNQLMLLTTLLIVMTSIVVHLLHRFTDFAYAYTILRNGADDYVYSGVTWVLFAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
PIVFFGMMVVTSKRESLAFSYWMMLTLTFASISTVAGGQGLVEYHFSIFVVLAILSFMRR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IDLILYSAGIFAVQHLVGYFLIPEMICGTSDYPFSLLLVHAVYLILLSVVLVAQIHFRNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETERVEAQEQETRQLLQQAIHDVSVLVQSLNSHAEELESAANQSLESGEQIAVTVDPIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
HASSQQESMVQGADEIHSIRSLTALIQERMAQTAAASSRIAKDALAGNKDMRLMEAKVQE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IITESEQLDRIVATMSNRSTEIQGILQQVGSISEQTNMLALNASIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHCCEEEEECCHHHHHCCCCCCCHHHH
ASEVGKLAVQSREYASEMTRVLGGLMEDTTVVSKSAHLFKQATENCQTVTNDVTAVFDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEDVSEIDEQIASIQETRQRVTTQMEALETRLESTKYAANELQQQIHHVAAATEEQVAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELSSMSDRLALTANSLEDVTTQLEDHATRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMSLIKRNQLMLLTTLLIVMTSIVVHLLHRFTDFAYAYTILRNGADDYVYSGVTWVLFAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
PIVFFGMMVVTSKRESLAFSYWMMLTLTFASISTVAGGQGLVEYHFSIFVVLAILSFMRR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IDLILYSAGIFAVQHLVGYFLIPEMICGTSDYPFSLLLVHAVYLILLSVVLVAQIHFRNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETERVEAQEQETRQLLQQAIHDVSVLVQSLNSHAEELESAANQSLESGEQIAVTVDPIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHH
HASSQQESMVQGADEIHSIRSLTALIQERMAQTAAASSRIAKDALAGNKDMRLMEAKVQE
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IITESEQLDRIVATMSNRSTEIQGILQQVGSISEQTNMLALNASIEAARAGEAGRGFAVV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHCCEEEEECCHHHHHCCCCCCCHHHH
ASEVGKLAVQSREYASEMTRVLGGLMEDTTVVSKSAHLFKQATENCQTVTNDVTAVFDRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEDVSEIDEQIASIQETRQRVTTQMEALETRLESTKYAANELQQQIHHVAAATEEQVAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELSSMSDRLALTANSLEDVTTQLEDHATRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]