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The map label for this gene is cdd [H]

Identifier: 229916957

GI number: 229916957

Start: 1208520

End: 1208918

Strand: Reverse

Name: cdd [H]

Synonym: EAT1b_1231

Alternate gene names: 229916957

Gene position: 1208918-1208520 (Counterclockwise)

Preceding gene: 229916958

Following gene: 229916954

Centisome position: 40.3

GC content: 52.38

Gene sequence:

>399_bases
ATGAACCAACAACAATTAGTCGAGCGCGCACGCCAATTGAAGGACAATGCGTATTCACCATATTCGAAGTTCCGCGTCGG
GGCGGCACTTCTCATGAAGGATGGTACGGTCATCGACGGCGTCAACGTCGAGAACGTCTCGTTCGGAGCAACAAACTGTG
CAGAGCGCACAGCCATTTTCACAGCGGTCGCAAAAGGATACAAAAAAGGTGACTTCGAAGCGGTTGCCGTGTCTGGGGAC
ACGGAAGACTTCTTGCCACCATGTAGTATCTGCCGTCAGGTCATGGTCGAGTTTGGCGATCCTGACTTCAAAGTACTGCT
CACAAACGGCAACGCCGATGTGAAAGAAGTGACGCTTGGGGAGCTCGTCCCACTTGCGTTCACCGATTTGGATATGTGA

Upstream 100 bases:

>100_bases
GACTTCTCTTTGGGCTGGGTGTATGCTAAAAATCCTGCCCAAAATGAGAGGCATGGGGACTGGCATCAGTTCATTCGATA
TTCGAGAGGAATGACTTAAG

Downstream 100 bases:

>100_bases
TGTTGGGCCCCTCAGATTTCTGAGGGGTTTTCTTATCCAAAAAAGCGAAAAAATAATCGCGGAATGGCTTGAACAATGTA
AAGAAGCAGTTCTGAAAAAT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MNQQQLVERARQLKDNAYSPYSKFRVGAALLMKDGTVIDGVNVENVSFGATNCAERTAIFTAVAKGYKKGDFEAVAVSGD
TEDFLPPCSICRQVMVEFGDPDFKVLLTNGNADVKEVTLGELVPLAFTDLDM

Sequences:

>Translated_132_residues
MNQQQLVERARQLKDNAYSPYSKFRVGAALLMKDGTVIDGVNVENVSFGATNCAERTAIFTAVAKGYKKGDFEAVAVSGD
TEDFLPPCSICRQVMVEFGDPDFKVLLTNGNADVKEVTLGELVPLAFTDLDM
>Mature_132_residues
MNQQQLVERARQLKDNAYSPYSKFRVGAALLMKDGTVIDGVNVENVSFGATNCAERTAIFTAVAKGYKKGDFEAVAVSGD
TEDFLPPCSICRQVMVEFGDPDFKVLLTNGNADVKEVTLGELVPLAFTDLDM

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=130, Percent_Identity=44.6153846153846, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551074, Length=127, Percent_Identity=49.6062992125984, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17540514, Length=125, Percent_Identity=47.2, Blast_Score=111, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323274, Length=113, Percent_Identity=39.8230088495575, Blast_Score=97, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24582744, Length=107, Percent_Identity=40.1869158878505, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582741, Length=130, Percent_Identity=37.6923076923077, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920920, Length=109, Percent_Identity=42.2018348623853, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14359; Mature: 14359

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQQLVERARQLKDNAYSPYSKFRVGAALLMKDGTVIDGVNVENVSFGATNCAERTAIF
CCHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCEECCCCCCCCCCCCCCHHHHHHHH
TAVAKGYKKGDFEAVAVSGDTEDFLPPCSICRQVMVEFGDPDFKVLLTNGNADVKEVTLG
HHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
ELVPLAFTDLDM
HEHHHHEECCCC
>Mature Secondary Structure
MNQQQLVERARQLKDNAYSPYSKFRVGAALLMKDGTVIDGVNVENVSFGATNCAERTAIF
CCHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCEECCCCCCCCCCCCCCHHHHHHHH
TAVAKGYKKGDFEAVAVSGDTEDFLPPCSICRQVMVEFGDPDFKVLLTNGNADVKEVTLG
HHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
ELVPLAFTDLDM
HEHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]