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The map label for this gene is trpGD [H]

Identifier: 229916844

GI number: 229916844

Start: 1095205

End: 1095780

Strand: Direct

Name: trpGD [H]

Synonym: EAT1b_1117

Alternate gene names: 229916844

Gene position: 1095205-1095780 (Clockwise)

Preceding gene: 229916843

Following gene: 229916853

Centisome position: 36.51

GC content: 58.16

Gene sequence:

>576_bases
ATGATTCTCCTCATCGACAACTACGATTCGTTCACGTATAACGTCTATCAGGACGTCGCCCGCTTCAGTGACGTCTGCGT
CATCCGGAATGATGAACATACTATAGAAGAAATCCGTCGCATGAACCCGAGTGGCATCATCCTTTCTCCCGGTCCCGGTG
GTCCCAAAGACGCCGGTGTCTCGCTCGCGGTCGTGCGACAACTGTCCGGTTACATCCCGATTCTCGGGGTCTGTCTCGGT
CACCAGGTCATCGCTGAGGCGTTCGGTGGAGTCGTCGGTCGGGCGAACGAGGTGATGCATGGGAAAGTCTCACGGATCAA
TACGGTGCCAGGCGTCCTCTTCGATGGCTTGTCGATGGACGTCATGCGCTATCACTCGCTCGTCGTACAAGAGACCGAAC
TGACGGTCACGGCCGAGACGACAGACGGTGTCATCATGGCACTCGAGCACCCGACGCATCCGACGTACGGCGTCCAGTTC
CACCCCGAATCGATCGGAACGCCGGACGGACGTGGCATCTTCGAGCGCTTCGTCCAACTGTGCACGAAAAAACCGGGGCA
CGTGTCCCCGGTTTGA

Upstream 100 bases:

>100_bases
CCCACGTCCAAGCCGGCGCCGGCATCGTCTATGACTCAGACCCGGTATCGGAATATGAAGAAACGCTGCATAAAGCCAAA
TCCCTATTGGAGGTGTTCGC

Downstream 100 bases:

>100_bases
GTGTCAGCCTAAAAAGTCTTCTCGCTGAAAATCATGTTTGTCGATTTTGATATTGTCACAGGCCACCCCGTTCGTCCGGA
GCACCTGGATCGTTTCACGC

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MILLIDNYDSFTYNVYQDVARFSDVCVIRNDEHTIEEIRRMNPSGIILSPGPGGPKDAGVSLAVVRQLSGYIPILGVCLG
HQVIAEAFGGVVGRANEVMHGKVSRINTVPGVLFDGLSMDVMRYHSLVVQETELTVTAETTDGVIMALEHPTHPTYGVQF
HPESIGTPDGRGIFERFVQLCTKKPGHVSPV

Sequences:

>Translated_191_residues
MILLIDNYDSFTYNVYQDVARFSDVCVIRNDEHTIEEIRRMNPSGIILSPGPGGPKDAGVSLAVVRQLSGYIPILGVCLG
HQVIAEAFGGVVGRANEVMHGKVSRINTVPGVLFDGLSMDVMRYHSLVVQETELTVTAETTDGVIMALEHPTHPTYGVQF
HPESIGTPDGRGIFERFVQLCTKKPGHVSPV
>Mature_191_residues
MILLIDNYDSFTYNVYQDVARFSDVCVIRNDEHTIEEIRRMNPSGIILSPGPGGPKDAGVSLAVVRQLSGYIPILGVCLG
HQVIAEAFGGVVGRANEVMHGKVSRINTVPGVLFDGLSMDVMRYHSLVVQETELTVTAETTDGVIMALEHPTHPTYGVQF
HPESIGTPDGRGIFERFVQLCTKKPGHVSPV

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=48.9247311827957, Blast_Score=163, Evalue=6e-42,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=41.3612565445026, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786215, Length=154, Percent_Identity=29.8701298701299, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322638, Length=177, Percent_Identity=44.6327683615819, Blast_Score=147, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=29.5238095238095, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 20801; Mature: 20801

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTYNVYQDVARFSDVCVIRNDEHTIEEIRRMNPSGIILSPGPGGPKDAGV
CEEEEECCCCCCHHHHHHHHHHHCEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCCCCH
SLAVVRQLSGYIPILGVCLGHQVIAEAFGGVVGRANEVMHGKVSRINTVPGVLFDGLSMD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHCHHHHHCCCCHHHHCCCCHH
VMRYHSLVVQETELTVTAETTDGVIMALEHPTHPTYGVQFHPESIGTPDGRGIFERFVQL
HHHHHHHHEEECEEEEEEECCCCEEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHH
CTKKPGHVSPV
HCCCCCCCCCC
>Mature Secondary Structure
MILLIDNYDSFTYNVYQDVARFSDVCVIRNDEHTIEEIRRMNPSGIILSPGPGGPKDAGV
CEEEEECCCCCCHHHHHHHHHHHCEEEEECCHHHHHHHHHCCCCCEEECCCCCCCCCCCH
SLAVVRQLSGYIPILGVCLGHQVIAEAFGGVVGRANEVMHGKVSRINTVPGVLFDGLSMD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHCHHHHHCCCCHHHHCCCCHH
VMRYHSLVVQETELTVTAETTDGVIMALEHPTHPTYGVQFHPESIGTPDGRGIFERFVQL
HHHHHHHHEEECEEEEEEECCCCEEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHH
CTKKPGHVSPV
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]