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The map label for this gene is trpE [H]

Identifier: 229916843

GI number: 229916843

Start: 1093877

End: 1095208

Strand: Direct

Name: trpE [H]

Synonym: EAT1b_1116

Alternate gene names: 229916843

Gene position: 1093877-1095208 (Clockwise)

Preceding gene: 229916842

Following gene: 229916844

Centisome position: 36.46

GC content: 58.48

Gene sequence:

>1332_bases
ATGCAACAACGGATGATCAATGGTGACGAACTCACACCGGTGGCAATCTTCCACCGGCTGCAAGGTGAACGAAAGGTATT
ACTCGAGAGTCGCGCGGAAGGCAAGCACGGCCGCTACTCCATCATCGCGGCGAACCCGGTCGAGACGATCCGAGTCGATG
GGAACGACGTGACAGATGCAACGGGGACGGTCTATGCGGACGACCCGCTCCATGCCTTATCCGAACGCATCACACGTGAC
GACTTCACTGCACCGTACCCGTTCATCGGCGGTGCCGTCGGCTATATCGGCTACGACTTGCTTCGGGTATATGAACCGAT
CCCAAACACGCCGACCGTGACGCGTGATTTGCCGGACGCCCTCTTCCAGCGCTATGAGACGATTGTCTTATATGACCACC
TCGAGGAACAGGTCATCCTGATCGATACGAGTGAGACGGATGCGACGATGCGACTCGAGTCCATCCGGGAACAGCTCGAG
ACACCGGAGACGCACGCCCTCGAACCAGTCGTCCGGACGAGCGAGCGCATCTTGACGCCGAAGGACGAATTTATCGACCG
TGTGCTCCAGGCAAAAGAGGCGATCCTTGCGGGCGAGGTGTTCCAACTCGTCTTGTCGCAACGAATCGACGCGACGTTCA
CCGGGGACCCATTCCACTTTTACCGGACGCTGCGGAAACAAAATCCGAGTCCGTACTTGTTCTACATCGACCTCGGGGAA
GCAATCGTCCTCGGTGCATCACCGGAGAGTCTCGTCCGGGTCGAGAACGGCAAAGTGACGACGAACCCGATCGCCGGGAC
ACGCCCACGTGGGAAGACCGTCGAGGAAGACATGCGTCACGCGGAGTCACTCCTTCAAGACGAGAAAGAACTCGCCGAGC
ATCGGATGCTCCTCGACCTTGGACGGAACGATATCGGGCGGGTCGCGAAAGTCGGCACGGTTACCATCCCGAAACACATC
GAGCTCGAACGATTCAAAAACGTGATGCATCTCGTCTCCGAAGTCGAAGGGGATTTACGTGACGATGTGACCCCAATCGA
TGCGCTCCGTGCCTGTCTTCCGGCAGGTACCGTCTCCGGGGCTCCAAAGATTCGGGCGATGCAGTTGATCGACGAGCTTG
AGACGGTGAAACGGGAAGTCTACGCCGGGGCGGTCGGCTATCTCGACGTCCGGGGCGGATTCGACTTCGCCCTTGCCATC
CGGACGATGGTCGTCCAAGGTGACACGGCCCACGTCCAAGCCGGCGCCGGCATCGTCTATGACTCAGACCCGGTATCGGA
ATATGAAGAAACGCTGCATAAAGCCAAATCCCTATTGGAGGTGTTCGCATGA

Upstream 100 bases:

>100_bases
TCTTTCAACGAAGGTGGCAACACGGGGAATCTCCTCGTCCTTCATGTCCGATTGGGCATGCGGGACGGGGAGATTTTTTT
AGTTTAAGGAGGAGATGTTG

Downstream 100 bases:

>100_bases
TTCTCCTCATCGACAACTACGATTCGTTCACGTATAACGTCTATCAGGACGTCGCCCGCTTCAGTGACGTCTGCGTCATC
CGGAATGATGAACATACTAT

Product: anthranilate synthase component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MQQRMINGDELTPVAIFHRLQGERKVLLESRAEGKHGRYSIIAANPVETIRVDGNDVTDATGTVYADDPLHALSERITRD
DFTAPYPFIGGAVGYIGYDLLRVYEPIPNTPTVTRDLPDALFQRYETIVLYDHLEEQVILIDTSETDATMRLESIREQLE
TPETHALEPVVRTSERILTPKDEFIDRVLQAKEAILAGEVFQLVLSQRIDATFTGDPFHFYRTLRKQNPSPYLFYIDLGE
AIVLGASPESLVRVENGKVTTNPIAGTRPRGKTVEEDMRHAESLLQDEKELAEHRMLLDLGRNDIGRVAKVGTVTIPKHI
ELERFKNVMHLVSEVEGDLRDDVTPIDALRACLPAGTVSGAPKIRAMQLIDELETVKREVYAGAVGYLDVRGGFDFALAI
RTMVVQGDTAHVQAGAGIVYDSDPVSEYEETLHKAKSLLEVFA

Sequences:

>Translated_443_residues
MQQRMINGDELTPVAIFHRLQGERKVLLESRAEGKHGRYSIIAANPVETIRVDGNDVTDATGTVYADDPLHALSERITRD
DFTAPYPFIGGAVGYIGYDLLRVYEPIPNTPTVTRDLPDALFQRYETIVLYDHLEEQVILIDTSETDATMRLESIREQLE
TPETHALEPVVRTSERILTPKDEFIDRVLQAKEAILAGEVFQLVLSQRIDATFTGDPFHFYRTLRKQNPSPYLFYIDLGE
AIVLGASPESLVRVENGKVTTNPIAGTRPRGKTVEEDMRHAESLLQDEKELAEHRMLLDLGRNDIGRVAKVGTVTIPKHI
ELERFKNVMHLVSEVEGDLRDDVTPIDALRACLPAGTVSGAPKIRAMQLIDELETVKREVYAGAVGYLDVRGGFDFALAI
RTMVVQGDTAHVQAGAGIVYDSDPVSEYEETLHKAKSLLEVFA
>Mature_443_residues
MQQRMINGDELTPVAIFHRLQGERKVLLESRAEGKHGRYSIIAANPVETIRVDGNDVTDATGTVYADDPLHALSERITRD
DFTAPYPFIGGAVGYIGYDLLRVYEPIPNTPTVTRDLPDALFQRYETIVLYDHLEEQVILIDTSETDATMRLESIREQLE
TPETHALEPVVRTSERILTPKDEFIDRVLQAKEAILAGEVFQLVLSQRIDATFTGDPFHFYRTLRKQNPSPYLFYIDLGE
AIVLGASPESLVRVENGKVTTNPIAGTRPRGKTVEEDMRHAESLLQDEKELAEHRMLLDLGRNDIGRVAKVGTVTIPKHI
ELERFKNVMHLVSEVEGDLRDDVTPIDALRACLPAGTVSGAPKIRAMQLIDELETVKREVYAGAVGYLDVRGGFDFALAI
RTMVVQGDTAHVQAGAGIVYDSDPVSEYEETLHKAKSLLEVFA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=417, Percent_Identity=33.5731414868106, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1787518, Length=368, Percent_Identity=38.8586956521739, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1786809, Length=274, Percent_Identity=29.9270072992701, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082077, Length=256, Percent_Identity=30.46875, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320935, Length=455, Percent_Identity=38.6813186813187, Blast_Score=260, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6324361, Length=398, Percent_Identity=23.6180904522613, Blast_Score=114, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 49433; Mature: 49433

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRMINGDELTPVAIFHRLQGERKVLLESRAEGKHGRYSIIAANPVETIRVDGNDVTDA
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCCCCCC
TGTVYADDPLHALSERITRDDFTAPYPFIGGAVGYIGYDLLRVYEPIPNTPTVTRDLPDA
CCEEEECCHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
LFQRYETIVLYDHLEEQVILIDTSETDATMRLESIREQLETPETHALEPVVRTSERILTP
HHHHHCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
KDEFIDRVLQAKEAILAGEVFQLVLSQRIDATFTGDPFHFYRTLRKQNPSPYLFYIDLGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCEEEEEECCC
AIVLGASPESLVRVENGKVTTNPIAGTRPRGKTVEEDMRHAESLLQDEKELAEHRMLLDL
EEEECCCCHHEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRNDIGRVAKVGTVTIPKHIELERFKNVMHLVSEVEGDLRDDVTPIDALRACLPAGTVSG
CCCHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCC
APKIRAMQLIDELETVKREVYAGAVGYLDVRGGFDFALAIRTMVVQGDTAHVQAGAGIVY
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCEEECCCEEEE
DSDPVSEYEETLHKAKSLLEVFA
CCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQQRMINGDELTPVAIFHRLQGERKVLLESRAEGKHGRYSIIAANPVETIRVDGNDVTDA
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEECCCEEEEECCCCCCCC
TGTVYADDPLHALSERITRDDFTAPYPFIGGAVGYIGYDLLRVYEPIPNTPTVTRDLPDA
CCEEEECCHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
LFQRYETIVLYDHLEEQVILIDTSETDATMRLESIREQLETPETHALEPVVRTSERILTP
HHHHHCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
KDEFIDRVLQAKEAILAGEVFQLVLSQRIDATFTGDPFHFYRTLRKQNPSPYLFYIDLGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCEEEEEECCC
AIVLGASPESLVRVENGKVTTNPIAGTRPRGKTVEEDMRHAESLLQDEKELAEHRMLLDL
EEEECCCCHHEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRNDIGRVAKVGTVTIPKHIELERFKNVMHLVSEVEGDLRDDVTPIDALRACLPAGTVSG
CCCHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCC
APKIRAMQLIDELETVKREVYAGAVGYLDVRGGFDFALAIRTMVVQGDTAHVQAGAGIVY
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCEEECCCEEEE
DSDPVSEYEETLHKAKSLLEVFA
CCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]