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The map label for this gene is ribD [H]

Identifier: 229916731

GI number: 229916731

Start: 947624

End: 948688

Strand: Reverse

Name: ribD [H]

Synonym: EAT1b_1004

Alternate gene names: 229916731

Gene position: 948688-947624 (Counterclockwise)

Preceding gene: 229916732

Following gene: 229916730

Centisome position: 31.62

GC content: 56.71

Gene sequence:

>1065_bases
ATGAAACAGTACATGGAACAGGCCATTCAATTGGCGAAATCAGCCGATGGACAGACCGGCGTCAATCCACTCGTCGGTGC
CGTTCTCGTGAAAGACGGACGCATCGTTGGGATGGGTGCCCATCTTAAGGCGGGCGAACCACATGCTGAAGTGCATGCGA
TCCGAATGGCCGGTGCGGCTGCGTATGGGGCGACCTTATATGTCACGCTCGAACCGTGCTCACATCATGGCAAGACACCG
CCGTGCGCCGATCTGATTGTGGAATCGGGTATCAAACGCGTCGTCATCGCCATGAAAGATCCGAACCCGCTCGTCGCAGG
CAACGGGATCATGCGTCTGCAAGCGGCCGGTGTCGAAGTCGATGTGGGGTTGCTTGAGGCGGAAGCGCGTGCCTTGAATC
CGGCGTTCTTGCGGTCGCTTGAAACGAAACGACCATACGTCATCTTGAAGACGGCGACGAGTCTCGATGGCAAAGTCGCC
TTAGAGACGGGGGAGAGTCAATGGGTGACGAGTTCAGAAGCCCGTCGTGATGTGCATGAACTTCGTGCCACGGTCGATGC
GATATTGACCGGGATTGGCACGGTGCTCGCGGATGACCCATCGCTCACGGTTCGATTGGACCGCGTGACGCGTCAGCCGA
AACGAGTGGTGCTCGACCGTGACCTTAGGTTACCGTTCGCCAGTACGTTAGCACGTACCGCCGAAGACGTCCCGGTGCTC
CTCTTCACTTCGTCAGATGAAGCCGAACGACGTGAACGAGCCAAAGCCGCCGGAATCGAATTATTCGATTACACGTCACT
CGGTACGGTTCTTGAGACGCTATACGCAAATGGAATCGGGCGTGTGTTGATCGAGGCCGGACCGACGCTCGTCACTTCCC
TTCTTGATGGAGGCTACGTGGACGAATGGGTCGCCTATCAATCACCACGGGTGTTCGGTGGAAAACATGGCGTCTATCGC
TCACAGCAGGAAGGGACGATCGATGGGATATCCCGTTTTACAATCCATCAGGTTGAAACGATTGGTCCCGACCTAAAAGT
CGTCCTTCGAAAGGGGGCGCTCTGA

Upstream 100 bases:

>100_bases
GTTTATTTGGCTTGCCAAAAAGTCGACGAAACCCTCCCACCAAGACCCTAAGGACCGCTCCTTAGGGTCTTTTGTTTGTA
CGGAAAAAGGAGGGAGAACG

Downstream 100 bases:

>100_bases
TGTTCACGGGAATCGTAGAAGAAATCGGATCGGTCAAAGCGGTCAAGCGCAACGGACCGTCTTTACGACTCGTCTTGTCC
GCTGTGAAAGTGCTTGACGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKQYMEQAIQLAKSADGQTGVNPLVGAVLVKDGRIVGMGAHLKAGEPHAEVHAIRMAGAAAYGATLYVTLEPCSHHGKTP
PCADLIVESGIKRVVIAMKDPNPLVAGNGIMRLQAAGVEVDVGLLEAEARALNPAFLRSLETKRPYVILKTATSLDGKVA
LETGESQWVTSSEARRDVHELRATVDAILTGIGTVLADDPSLTVRLDRVTRQPKRVVLDRDLRLPFASTLARTAEDVPVL
LFTSSDEAERRERAKAAGIELFDYTSLGTVLETLYANGIGRVLIEAGPTLVTSLLDGGYVDEWVAYQSPRVFGGKHGVYR
SQQEGTIDGISRFTIHQVETIGPDLKVVLRKGAL

Sequences:

>Translated_354_residues
MKQYMEQAIQLAKSADGQTGVNPLVGAVLVKDGRIVGMGAHLKAGEPHAEVHAIRMAGAAAYGATLYVTLEPCSHHGKTP
PCADLIVESGIKRVVIAMKDPNPLVAGNGIMRLQAAGVEVDVGLLEAEARALNPAFLRSLETKRPYVILKTATSLDGKVA
LETGESQWVTSSEARRDVHELRATVDAILTGIGTVLADDPSLTVRLDRVTRQPKRVVLDRDLRLPFASTLARTAEDVPVL
LFTSSDEAERRERAKAAGIELFDYTSLGTVLETLYANGIGRVLIEAGPTLVTSLLDGGYVDEWVAYQSPRVFGGKHGVYR
SQQEGTIDGISRFTIHQVETIGPDLKVVLRKGAL
>Mature_354_residues
MKQYMEQAIQLAKSADGQTGVNPLVGAVLVKDGRIVGMGAHLKAGEPHAEVHAIRMAGAAAYGATLYVTLEPCSHHGKTP
PCADLIVESGIKRVVIAMKDPNPLVAGNGIMRLQAAGVEVDVGLLEAEARALNPAFLRSLETKRPYVILKTATSLDGKVA
LETGESQWVTSSEARRDVHELRATVDAILTGIGTVLADDPSLTVRLDRVTRQPKRVVLDRDLRLPFASTLARTAEDVPVL
LFTSSDEAERRERAKAAGIELFDYTSLGTVLETLYANGIGRVLIEAGPTLVTSLLDGGYVDEWVAYQSPRVFGGKHGVYR
SQQEGTIDGISRFTIHQVETIGPDLKVVLRKGAL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=366, Percent_Identity=44.8087431693989, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI145693172, Length=148, Percent_Identity=36.4864864864865, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38034; Mature: 38034

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYMEQAIQLAKSADGQTGVNPLVGAVLVKDGRIVGMGAHLKAGEPHAEVHAIRMAGAA
CHHHHHHHHHHHHCCCCCCCCCHHHHEEEEECCEEEEECCCCCCCCCCHHEEEEEHHCCE
AYGATLYVTLEPCSHHGKTPPCADLIVESGIKRVVIAMKDPNPLVAGNGIMRLQAAGVEV
ECCEEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCEEECCCEEEEEECCEEE
DVGLLEAEARALNPAFLRSLETKRPYVILKTATSLDGKVALETGESQWVTSSEARRDVHE
EEEEEHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHH
LRATVDAILTGIGTVLADDPSLTVRLDRVTRQPKRVVLDRDLRLPFASTLARTAEDVPVL
HHHHHHHHHHHHHHHEECCCCEEEEEHHHCCCCHHEEECCCCCCCHHHHHHHHHCCCEEE
LFTSSDEAERRERAKAAGIELFDYTSLGTVLETLYANGIGRVLIEAGPTLVTSLLDGGYV
EEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCH
DEWVAYQSPRVFGGKHGVYRSQQEGTIDGISRFTIHQVETIGPDLKVVLRKGAL
HHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure
MKQYMEQAIQLAKSADGQTGVNPLVGAVLVKDGRIVGMGAHLKAGEPHAEVHAIRMAGAA
CHHHHHHHHHHHHCCCCCCCCCHHHHEEEEECCEEEEECCCCCCCCCCHHEEEEEHHCCE
AYGATLYVTLEPCSHHGKTPPCADLIVESGIKRVVIAMKDPNPLVAGNGIMRLQAAGVEV
ECCEEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCEEECCCEEEEEECCEEE
DVGLLEAEARALNPAFLRSLETKRPYVILKTATSLDGKVALETGESQWVTSSEARRDVHE
EEEEEHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHH
LRATVDAILTGIGTVLADDPSLTVRLDRVTRQPKRVVLDRDLRLPFASTLARTAEDVPVL
HHHHHHHHHHHHHHHEECCCCEEEEEHHHCCCCHHEEECCCCCCCHHHHHHHHHCCCEEE
LFTSSDEAERRERAKAAGIELFDYTSLGTVLETLYANGIGRVLIEAGPTLVTSLLDGGYV
EEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCH
DEWVAYQSPRVFGGKHGVYRSQQEGTIDGISRFTIHQVETIGPDLKVVLRKGAL
HHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]