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The map label for this gene is uvrB [H]

Identifier: 229916613

GI number: 229916613

Start: 838000

End: 839970

Strand: Reverse

Name: uvrB [H]

Synonym: EAT1b_0885

Alternate gene names: 229916613

Gene position: 839970-838000 (Counterclockwise)

Preceding gene: 229916616

Following gene: 229916612

Centisome position: 28.0

GC content: 53.12

Gene sequence:

>1971_bases
ATGGAATCGATTCCGTTTGCATTACAATCTGAATTTCAACCAGGGGGTGACCAGCCTGAAGCGATTCGACAGCTTGTCGA
AGGTGTGAATCGAGGTGACCGGTATCAGACGCTCCTCGGGGCAACGGGTACGGGGAAAACGTTTACCGTCTCGAACGTCA
TTCAAGAAGTGAAGAAGCCGACACTCGTCCTCGCCCATAATAAGACGCTCGCCGGGCAGCTTTACTCGGAGTTCAAAGAA
TTCTTCCCGAACAACGCCGTCGAGTACTTCGTCAGTTACTATGACTACTATCAACCTGAGGCATACGTGCCGTCGACGGA
TACGTTCATCGAGAAGGACGCGTCGATCAATGATGAAATCGATAAGCTGCGTCACTCGGCGACGTCGGCTCTCTTTGAGC
GCGATGACGTCATCATCGTCGCATCCGTTTCCTGTATATACGGTCTCGGTAACCCGGAAGAATATCGGAGCCTCGTCTTG
AGCCTTCGCGTCGGGAAAGAGATGGGGCGTGACGAGATGTTACGTAAACTCATCGACATTCAATATGAACGGAACGATAT
CGACTTCCAACGTGGACGTTTCCGTGTCCGTGGGGATGTCGTCGAGATCTTCCCGGCGTCGCGTGACGAACACTGCATGC
GCATCGAGTTTTTCGGGGACGAGATTGACCGCATCCGGGAGATGGACCCGTTGACGGGGGAAATCATCGCAGACCGTGAC
CACGTCGCCATCTTCCCGGCATCCCACTTCGTCACACGTGACGAAAAATTGCAAAAGGCAATCGTCAACATCGAAGCGGA
ACTTGAGGAACAGCTTGAGAAGTTCCGGGAAGAAGGGAAACTGCTTGAAGCGCAGCGACTCGAGCAACGAACGCATTACG
ATTTGGAAATGATGCGTGAGATGGGGTATTGTTCAGGAATCGAGAACTATTCGCGCCACTTGAACTTGATGCCGGAAGGC
TCGACCCCGTATACGCTACTCGATTACTTCCCGGAAGATTTCTTACTCGTCGCCGATGAGTCGCACGTGACGCTTCCACA
AGTACGCGGCATGTATAACGGGGACCAGGCACGGAAACAAGTGCTCGTCGACCATGGTTTCCGTCTCCCTTCGGCGAAGG
ATAACCGTCCGCTCAAGTTTGATGAGTTCGAGAAGAAAGTCTCACAAGCAATCTTCATCTCGGCGACACCAGGTCCATAC
GAACTCGAACATACACCGAACATGATCGAGCAGATCATCCGTCCGACCGGGTTACTTGATCCGACAATCGAGATTCATCC
GATCAAAGGTCAGATTGACTACTTGATGGATCAGATTCGCGAACGCATCAAGCGTGACGAGCGGGTACTCGTGACGACGC
TCACGAAGAAGATGGCCGAGGACTTATCCGATTACTTGCGCGAAGCGGGAATCAAGGTCAACTACATGCATTCTGAGATC
AAGACGCTCGAGCGAATTGAAATCATTCGTGACCTTCGACTCGGGAAGTATGACGTACTCGTCGGGATCAACTTGTTGCG
GGAGGGTCTCGACATTCCAGAAGTCAGTCTCGTGACGATTCTCGATGCTGATAAGGAAGGATTCCTTCGTTCCGATCGCT
CGCTCATCCAGACGATTGGACGAGCGGCGCGTAATGCGAACGGACACGTCATCCTGTTCGCGGACAAGATGACCGACTCG
ATGGCGCGTGCCATCGAAGAGACGGATCGCCGTCGGTCAATTCAACAGGCTTATAATGAAGAACATGGCATCACCCCGCA
GACGATTCGAAAGGACGTGCGAGGGGTCATTCGGGCGACGGTCGAAGCGGAAGAGGAAGCACTCGAATCGCTCAGTACGA
TGAAGCCGGCCGAACGCGAGGCGGCGATCGCCAAGTTGGAAGAAGAAATGAAGCAAGCGGCACGCGACCTCCAGTTCGAA
CGCGCGGCCGAATTGCGTGACTTAATCTTGGAGTTGAAGGTAGGGAATTAA

Upstream 100 bases:

>100_bases
AGAAATGAATTGTATTAACCCACAAGCTAATAAGCGAATATTTGTTCGTGTCTATGGTATAATCAAGACACTTATGAAAT
GAGAAGGTGAGGAGTATCTT

Downstream 100 bases:

>100_bases
ATGGCTGAAAAGAAAAATGCGATTGTCATCAAAGGGGCACGCGTCAACAATTTAAAAAATATTGACATCGATATCCCACG
TGACCAGCTCGTCGTCTTGA

Product: excinuclease ABC, B subunit

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MESIPFALQSEFQPGGDQPEAIRQLVEGVNRGDRYQTLLGATGTGKTFTVSNVIQEVKKPTLVLAHNKTLAGQLYSEFKE
FFPNNAVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGNPEEYRSLVL
SLRVGKEMGRDEMLRKLIDIQYERNDIDFQRGRFRVRGDVVEIFPASRDEHCMRIEFFGDEIDRIREMDPLTGEIIADRD
HVAIFPASHFVTRDEKLQKAIVNIEAELEEQLEKFREEGKLLEAQRLEQRTHYDLEMMREMGYCSGIENYSRHLNLMPEG
STPYTLLDYFPEDFLLVADESHVTLPQVRGMYNGDQARKQVLVDHGFRLPSAKDNRPLKFDEFEKKVSQAIFISATPGPY
ELEHTPNMIEQIIRPTGLLDPTIEIHPIKGQIDYLMDQIRERIKRDERVLVTTLTKKMAEDLSDYLREAGIKVNYMHSEI
KTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVTILDADKEGFLRSDRSLIQTIGRAARNANGHVILFADKMTDS
MARAIEETDRRRSIQQAYNEEHGITPQTIRKDVRGVIRATVEAEEEALESLSTMKPAEREAAIAKLEEEMKQAARDLQFE
RAAELRDLILELKVGN

Sequences:

>Translated_656_residues
MESIPFALQSEFQPGGDQPEAIRQLVEGVNRGDRYQTLLGATGTGKTFTVSNVIQEVKKPTLVLAHNKTLAGQLYSEFKE
FFPNNAVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGNPEEYRSLVL
SLRVGKEMGRDEMLRKLIDIQYERNDIDFQRGRFRVRGDVVEIFPASRDEHCMRIEFFGDEIDRIREMDPLTGEIIADRD
HVAIFPASHFVTRDEKLQKAIVNIEAELEEQLEKFREEGKLLEAQRLEQRTHYDLEMMREMGYCSGIENYSRHLNLMPEG
STPYTLLDYFPEDFLLVADESHVTLPQVRGMYNGDQARKQVLVDHGFRLPSAKDNRPLKFDEFEKKVSQAIFISATPGPY
ELEHTPNMIEQIIRPTGLLDPTIEIHPIKGQIDYLMDQIRERIKRDERVLVTTLTKKMAEDLSDYLREAGIKVNYMHSEI
KTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVTILDADKEGFLRSDRSLIQTIGRAARNANGHVILFADKMTDS
MARAIEETDRRRSIQQAYNEEHGITPQTIRKDVRGVIRATVEAEEEALESLSTMKPAEREAAIAKLEEEMKQAARDLQFE
RAAELRDLILELKVGN
>Mature_656_residues
MESIPFALQSEFQPGGDQPEAIRQLVEGVNRGDRYQTLLGATGTGKTFTVSNVIQEVKKPTLVLAHNKTLAGQLYSEFKE
FFPNNAVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDKLRHSATSALFERDDVIIVASVSCIYGLGNPEEYRSLVL
SLRVGKEMGRDEMLRKLIDIQYERNDIDFQRGRFRVRGDVVEIFPASRDEHCMRIEFFGDEIDRIREMDPLTGEIIADRD
HVAIFPASHFVTRDEKLQKAIVNIEAELEEQLEKFREEGKLLEAQRLEQRTHYDLEMMREMGYCSGIENYSRHLNLMPEG
STPYTLLDYFPEDFLLVADESHVTLPQVRGMYNGDQARKQVLVDHGFRLPSAKDNRPLKFDEFEKKVSQAIFISATPGPY
ELEHTPNMIEQIIRPTGLLDPTIEIHPIKGQIDYLMDQIRERIKRDERVLVTTLTKKMAEDLSDYLREAGIKVNYMHSEI
KTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVTILDADKEGFLRSDRSLIQTIGRAARNANGHVILFADKMTDS
MARAIEETDRRRSIQQAYNEEHGITPQTIRKDVRGVIRATVEAEEEALESLSTMKPAEREAAIAKLEEEMKQAARDLQFE
RAAELRDLILELKVGN

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=669, Percent_Identity=58.4454409566517, Blast_Score=766, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 75368; Mature: 75368

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIPFALQSEFQPGGDQPEAIRQLVEGVNRGDRYQTLLGATGTGKTFTVSNVIQEVKKP
CCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEHHHHHHHHCCC
TLVLAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEI
EEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHH
DKLRHSATSALFERDDVIIVASVSCIYGLGNPEEYRSLVLSLRVGKEMGRDEMLRKLIDI
HHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
QYERNDIDFQRGRFRVRGDVVEIFPASRDEHCMRIEFFGDEIDRIREMDPLTGEIIADRD
EECCCCCCHHCCCEEEECCEEEECCCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEECCC
HVAIFPASHFVTRDEKLQKAIVNIEAELEEQLEKFREEGKLLEAQRLEQRTHYDLEMMRE
CEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
MGYCSGIENYSRHLNLMPEGSTPYTLLDYFPEDFLLVADESHVTLPQVRGMYNGDQARKQ
HHHHCCHHHHHHHEECCCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHCCCCCCHHHHHH
VLVDHGFRLPSAKDNRPLKFDEFEKKVSQAIFISATPGPYELEHTPNMIEQIIRPTGLLD
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCCCCC
PTIEIHPIKGQIDYLMDQIRERIKRDERVLVTTLTKKMAEDLSDYLREAGIKVNYMHSEI
CCEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHH
KTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVTILDADKEGFLRSDRSLIQTIG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
RAARNANGHVILFADKMTDSMARAIEETDRRRSIQQAYNEEHGITPQTIRKDVRGVIRAT
HHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VEAEEEALESLSTMKPAEREAAIAKLEEEMKQAARDLQFERAAELRDLILELKVGN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MESIPFALQSEFQPGGDQPEAIRQLVEGVNRGDRYQTLLGATGTGKTFTVSNVIQEVKKP
CCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEHHHHHHHHCCC
TLVLAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEI
EEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHH
DKLRHSATSALFERDDVIIVASVSCIYGLGNPEEYRSLVLSLRVGKEMGRDEMLRKLIDI
HHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
QYERNDIDFQRGRFRVRGDVVEIFPASRDEHCMRIEFFGDEIDRIREMDPLTGEIIADRD
EECCCCCCHHCCCEEEECCEEEECCCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEECCC
HVAIFPASHFVTRDEKLQKAIVNIEAELEEQLEKFREEGKLLEAQRLEQRTHYDLEMMRE
CEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
MGYCSGIENYSRHLNLMPEGSTPYTLLDYFPEDFLLVADESHVTLPQVRGMYNGDQARKQ
HHHHCCHHHHHHHEECCCCCCCCCHHHHHCCCCEEEEECCCCCCHHHHCCCCCCHHHHHH
VLVDHGFRLPSAKDNRPLKFDEFEKKVSQAIFISATPGPYELEHTPNMIEQIIRPTGLLD
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHCCCCCCC
PTIEIHPIKGQIDYLMDQIRERIKRDERVLVTTLTKKMAEDLSDYLREAGIKVNYMHSEI
CCEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHH
KTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVTILDADKEGFLRSDRSLIQTIG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
RAARNANGHVILFADKMTDSMARAIEETDRRRSIQQAYNEEHGITPQTIRKDVRGVIRAT
HHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VEAEEEALESLSTMKPAEREAAIAKLEEEMKQAARDLQFERAAELRDLILELKVGN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA