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The map label for this gene is uvrX [H]

Identifier: 229916557

GI number: 229916557

Start: 785718

End: 787013

Strand: Direct

Name: uvrX [H]

Synonym: EAT1b_0828

Alternate gene names: 229916557

Gene position: 785718-787013 (Clockwise)

Preceding gene: 229916550

Following gene: 229916558

Centisome position: 26.19

GC content: 58.02

Gene sequence:

>1296_bases
ATGCGCAGACGAATCTTTTGTATCGACAGCGTCTCGTTCTATGCCAGTTGCGAGTGTGCCGCGCGCAACAAAAATCCTTA
TCAGACGAAGCTCGTCGTCCTCTCGAACCTACAGGACAGCGGGGCACTCGTCCTCGCCGCGACCCCGAAGATGAAGCAGC
TCGGCATCAAGACCGGGTCACGCCGCTTCCACATCGACCGCCTCCCGTGGCACGAACGACGGGACGTTTTGTATGCCGAG
GCACGGATGAGTCATTATTTGAACGTTTCCATTCAAATCATCCACATCCTGCATCAGTTCGCCCCGCCCGAGGCGATTCG
CGTCTATTCGATTGATGAGACGCTCGTCGACATGAGCGGGACGGAGCGGTTGTTCGGAAATGACGAGCACGTCGCCCACC
TCATGCGTGCGACGATCTTTCGCTATACAGGCATTCCCGTCACCATCGGCATCGGACCGAACAACGTCCTCGCCAAGCTC
GTCCTCGATTTGCATGCAAAAAAGGAAGGTGTCGCCACGTGCCTTCTCCAAGACGTCGAACGGCTTATCCATCCGGCGCC
GATCGAGAAGATGTGGGGCGTCGGAACGAAGATGGCGGTCCACCTGCAGCGACTCGGCATCTGGACGATTGGGGACTTGG
CCCGCTACCCACTCGAATCCCTTCATGAAAAGTTCGGTGTCATCGGTGCAGAACTTTGGCATCACGCTTGGGGCATCGAC
GAGTCGCCGACCATCCTGCCGGCGAGCTCCTTGTTCGGTGCGAAACGGATGCGACCGAAGTCGATCGGACACGGCATCAC
CCTCATGAAAGACTACACGGCGTATTCCGCAATCCGGCTCGTCTTACAAGCGATTGCGGTCGAAGTCGGCATGCGAACCA
GGCAAGCGGGACTCGTCGGAGGGACAATCCATCTCGGGGTGCGCTATACGCGGACGAGCGACCGGGGTGGCTTCAGTAAA
CAAAAGAAGCTCCCCCGCTTCACAGCGGACGAGCAAGAGTTTCTCCCCATCTTATTGCAGCTATTTTTAGACGGCTGGGA
AGAGACGGAGGCCGTCCGTTACGTCTCGGTCGCTCTCGGCAAACTCGAGCCACGGAGCGACCACGTCCAGTTATCGTTCT
TCGAAGACGAATGGGCGAAAGCGAAACGGCTCGACTTCCTCGATTTGATCGACGGCCTGAACGTCCGGTTCGGTCGTGGC
ACGATCCGACCGGCGTCGAGCCTACTAAAAGACAGTCCGCTCCGGACGCGCCAACGTCTAATCGGCGGACATAAACAAGG
AGGCGATTCCTCATGA

Upstream 100 bases:

>100_bases
GTATTTGTAAAAATATTTTCAATTCACTATTTGAGATGATGTGAGACCGTGTTACGATGAAAAAAAACAGAACATTTGTT
CGTGAAAAGGAGTGGTGACG

Downstream 100 bases:

>100_bases
GCAAGACCCGCTATCGTGACCGGGGTGAGTTGAAATGGATCCCATTTCTCATGCCCGAGCACGTCGCCCTACTGAAACGT
TATTATGCCCAAATCCAAAA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MRRRIFCIDSVSFYASCECAARNKNPYQTKLVVLSNLQDSGALVLAATPKMKQLGIKTGSRRFHIDRLPWHERRDVLYAE
ARMSHYLNVSIQIIHILHQFAPPEAIRVYSIDETLVDMSGTERLFGNDEHVAHLMRATIFRYTGIPVTIGIGPNNVLAKL
VLDLHAKKEGVATCLLQDVERLIHPAPIEKMWGVGTKMAVHLQRLGIWTIGDLARYPLESLHEKFGVIGAELWHHAWGID
ESPTILPASSLFGAKRMRPKSIGHGITLMKDYTAYSAIRLVLQAIAVEVGMRTRQAGLVGGTIHLGVRYTRTSDRGGFSK
QKKLPRFTADEQEFLPILLQLFLDGWEETEAVRYVSVALGKLEPRSDHVQLSFFEDEWAKAKRLDFLDLIDGLNVRFGRG
TIRPASSLLKDSPLRTRQRLIGGHKQGGDSS

Sequences:

>Translated_431_residues
MRRRIFCIDSVSFYASCECAARNKNPYQTKLVVLSNLQDSGALVLAATPKMKQLGIKTGSRRFHIDRLPWHERRDVLYAE
ARMSHYLNVSIQIIHILHQFAPPEAIRVYSIDETLVDMSGTERLFGNDEHVAHLMRATIFRYTGIPVTIGIGPNNVLAKL
VLDLHAKKEGVATCLLQDVERLIHPAPIEKMWGVGTKMAVHLQRLGIWTIGDLARYPLESLHEKFGVIGAELWHHAWGID
ESPTILPASSLFGAKRMRPKSIGHGITLMKDYTAYSAIRLVLQAIAVEVGMRTRQAGLVGGTIHLGVRYTRTSDRGGFSK
QKKLPRFTADEQEFLPILLQLFLDGWEETEAVRYVSVALGKLEPRSDHVQLSFFEDEWAKAKRLDFLDLIDGLNVRFGRG
TIRPASSLLKDSPLRTRQRLIGGHKQGGDSS
>Mature_431_residues
MRRRIFCIDSVSFYASCECAARNKNPYQTKLVVLSNLQDSGALVLAATPKMKQLGIKTGSRRFHIDRLPWHERRDVLYAE
ARMSHYLNVSIQIIHILHQFAPPEAIRVYSIDETLVDMSGTERLFGNDEHVAHLMRATIFRYTGIPVTIGIGPNNVLAKL
VLDLHAKKEGVATCLLQDVERLIHPAPIEKMWGVGTKMAVHLQRLGIWTIGDLARYPLESLHEKFGVIGAELWHHAWGID
ESPTILPASSLFGAKRMRPKSIGHGITLMKDYTAYSAIRLVLQAIAVEVGMRTRQAGLVGGTIHLGVRYTRTSDRGGFSK
QKKLPRFTADEQEFLPILLQLFLDGWEETEAVRYVSVALGKLEPRSDHVQLSFFEDEWAKAKRLDFLDLIDGLNVRFGRG
TIRPASSLLKDSPLRTRQRLIGGHKQGGDSS

Specific function: Involved In Uv Protection And Mutation. Essential For Induced (Or Sos) Mutagenesis. May Modify The DNA Replication Machinery To Allow Bypass Synthesis Across A Damaged Template. [C]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=418, Percent_Identity=24.6411483253589, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786425, Length=290, Percent_Identity=23.448275862069, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 48459; Mature: 48459

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRIFCIDSVSFYASCECAARNKNPYQTKLVVLSNLQDSGALVLAATPKMKQLGIKTGS
CCCEEEEEECCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCHHHHCCCCCC
RRFHIDRLPWHERRDVLYAEARMSHYLNVSIQIIHILHQFAPPEAIRVYSIDETLVDMSG
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCC
TERLFGNDEHVAHLMRATIFRYTGIPVTIGIGPNNVLAKLVLDLHAKKEGVATCLLQDVE
CHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
RLIHPAPIEKMWGVGTKMAVHLQRLGIWTIGDLARYPLESLHEKFGVIGAELWHHAWGID
HHHCCCCHHHHHCCCHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCC
ESPTILPASSLFGAKRMRPKSIGHGITLMKDYTAYSAIRLVLQAIAVEVGMRTRQAGLVG
CCCCEEECHHHHCHHCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
GTIHLGVRYTRTSDRGGFSKQKKLPRFTADEQEFLPILLQLFLDGWEETEAVRYVSVALG
CEEEEEEEEEECCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KLEPRSDHVQLSFFEDEWAKAKRLDFLDLIDGLNVRFGRGTIRPASSLLKDSPLRTRQRL
CCCCCCCCEEEEEECHHHHHHHHCHHHHHHCCCCEEECCCCCCHHHHHHHCCCHHHHHHH
IGGHKQGGDSS
HCCCCCCCCCC
>Mature Secondary Structure
MRRRIFCIDSVSFYASCECAARNKNPYQTKLVVLSNLQDSGALVLAATPKMKQLGIKTGS
CCCEEEEEECCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCHHHHCCCCCC
RRFHIDRLPWHERRDVLYAEARMSHYLNVSIQIIHILHQFAPPEAIRVYSIDETLVDMSG
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCC
TERLFGNDEHVAHLMRATIFRYTGIPVTIGIGPNNVLAKLVLDLHAKKEGVATCLLQDVE
CHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
RLIHPAPIEKMWGVGTKMAVHLQRLGIWTIGDLARYPLESLHEKFGVIGAELWHHAWGID
HHHCCCCHHHHHCCCHHHHHHHHHCCCEEHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCC
ESPTILPASSLFGAKRMRPKSIGHGITLMKDYTAYSAIRLVLQAIAVEVGMRTRQAGLVG
CCCCEEECHHHHCHHCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
GTIHLGVRYTRTSDRGGFSKQKKLPRFTADEQEFLPILLQLFLDGWEETEAVRYVSVALG
CEEEEEEEEEECCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KLEPRSDHVQLSFFEDEWAKAKRLDFLDLIDGLNVRFGRGTIRPASSLLKDSPLRTRQRL
CCCCCCCCEEEEEECHHHHHHHHCHHHHHHCCCCEEECCCCCCHHHHHHHCCCHHHHHHH
IGGHKQGGDSS
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]