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The map label for this gene is ptsG [H]

Identifier: 229916497

GI number: 229916497

Start: 724276

End: 725802

Strand: Reverse

Name: ptsG [H]

Synonym: EAT1b_0767

Alternate gene names: 229916497

Gene position: 725802-724276 (Counterclockwise)

Preceding gene: 229916498

Following gene: 229916496

Centisome position: 24.19

GC content: 47.94

Gene sequence:

>1527_bases
ATGTTTAAGCAGATCTTTGGTGTTCTTCAAAAAGTCGGTAAAGCACTTATGCTTCCTGTTGCAATCTTGCCGGCAGCCGG
TCTTCTTCTTGCATTCGGTAACGCAATGCAAAACCCACAACTTACATCACGCGCTGGTTGGTTAACGAACGAAGGCGTCG
TGAAATTCGCTCAATTGATGGAGCAAGCAGGTGGAATCATCTTCTCGAACTTGGCGCTCTTGTTCGCAGTCGGTGTCGCC
ATCGGTTTAGCAGGTGACGGCGTAGCCGGACTTGCAGCAATCGTTGGATTCTTGATCATGAACAAAGTCATGGGTGTTTG
GCTCGAACTCACACCTGAAGTGTTAGCACAAGGTGACCCGGCTTACGCGAACGTACTCGGTATCCCAACGCTCCAAACAG
GGGTATTCGGAGGGATCATCATGGGTCTCATCGCCGCATGGGCCTATAACAAGTACTTCAATATCGAATTGCCACAGTTC
CTTGGTTTCTTCGCTGGTAAACGTTTCGTTCCAATCGTAACGGCAGTTGCAGCCGTTGTTGCTGGTTTCGTTTTACTATT
AGTATGGCCACCAGTTCAGCACGGATTGAACTCATTCTCAAACTTCATGTTGAATGAAAACCGTACATTTGCAGCGTTCA
TCTTCGGTTTAATCGAACGTTCATTGATTCCATTCGGTCTTCACCACATCTTCTACTCACCATTCTGGTTTGAATTCGGT
TCATACACAGATGCAGCGGGTAACGTTGTACGTGGTGACCAAGCGATCTTCTTCGCACAAATTCGTGACGGCGCTGAATT
GACGGCAGGTACGTTCATGACTGGTAAATTCCCGTTCATGATGTTCGGTCTTCCTGCAGCAGCACTCGCGATGTATCACG
AAGCACGTCCTGAGCGTAAAGCGGTTGTCGGTGGTCTCTTGGCTTCTGCTGCCCTTACATCGTTCTTGACTGGTATCACA
GAACCAATCGAGTTCTCATTCTTGTTCGTAGCACCACTTCTCTTTGCAGTACACGCAGTATTCGCAGGTCTTTCGTTCAT
GACGATGCACCTCTTGAACGTTAAGATCGGGATGACGTTCTCAGGTGGTTTGATCGACTTCTTGCTCTTCGGTGTTCTTC
CAGGTCGTACGGCTTGGTGGCTCGTCATTCCAGTCGGTCTCGTGTTCGCGGTTGTTTACTACTTCGGATTCCGTTTCGTT
ATCCGCAAGTTCAACCTCAAAACACCAGGTCGTGAAGATGAAGTTGTTGAACAATCAACAGCGACTGGTTCGGAACTTGC
ACAAGATATCCTCGTCGGTCTTGGTGGCTCACAAAACATCAAGCACCTCGATGCATGTATCACACGTCTTCGTGTCGAAG
TGAAAGATAAGAACCAAGTCAACAAAGATGAGTTGAAACGCCTTGGCGCATCTGGTGTCCTTGAAGTTGGTAACAACATT
CAAGCAATCTTCGGACCACGTTCGGACGCATTGAAATCAGAAATCCAAGCGGTCATCGCTTCAGGTAACGAAAAGAAAGC
CAACTAA

Upstream 100 bases:

>100_bases
TTATAAACGTGATTTATGAAAACGTTTAGATACGTCGGTTGTCTGACATCTACGCCGCTATCATATTGTTTATACGTACT
TAAAAAAGGAGGAAATGTTG

Downstream 100 bases:

>100_bases
TTGATGACTTAGACCAATCCTTCGGGGTTGGTCTTTTCTTTTTATATGAAACGGTTTCATCCAAACGTTTGAGGGAAAAA
GTAAGTATTCTGACAAAGGA

Product: PTS system, glucose-specific IIBC subunit

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MFKQIFGVLQKVGKALMLPVAILPAAGLLLAFGNAMQNPQLTSRAGWLTNEGVVKFAQLMEQAGGIIFSNLALLFAVGVA
IGLAGDGVAGLAAIVGFLIMNKVMGVWLELTPEVLAQGDPAYANVLGIPTLQTGVFGGIIMGLIAAWAYNKYFNIELPQF
LGFFAGKRFVPIVTAVAAVVAGFVLLLVWPPVQHGLNSFSNFMLNENRTFAAFIFGLIERSLIPFGLHHIFYSPFWFEFG
SYTDAAGNVVRGDQAIFFAQIRDGAELTAGTFMTGKFPFMMFGLPAAALAMYHEARPERKAVVGGLLASAALTSFLTGIT
EPIEFSFLFVAPLLFAVHAVFAGLSFMTMHLLNVKIGMTFSGGLIDFLLFGVLPGRTAWWLVIPVGLVFAVVYYFGFRFV
IRKFNLKTPGREDEVVEQSTATGSELAQDILVGLGGSQNIKHLDACITRLRVEVKDKNQVNKDELKRLGASGVLEVGNNI
QAIFGPRSDALKSEIQAVIASGNEKKAN

Sequences:

>Translated_508_residues
MFKQIFGVLQKVGKALMLPVAILPAAGLLLAFGNAMQNPQLTSRAGWLTNEGVVKFAQLMEQAGGIIFSNLALLFAVGVA
IGLAGDGVAGLAAIVGFLIMNKVMGVWLELTPEVLAQGDPAYANVLGIPTLQTGVFGGIIMGLIAAWAYNKYFNIELPQF
LGFFAGKRFVPIVTAVAAVVAGFVLLLVWPPVQHGLNSFSNFMLNENRTFAAFIFGLIERSLIPFGLHHIFYSPFWFEFG
SYTDAAGNVVRGDQAIFFAQIRDGAELTAGTFMTGKFPFMMFGLPAAALAMYHEARPERKAVVGGLLASAALTSFLTGIT
EPIEFSFLFVAPLLFAVHAVFAGLSFMTMHLLNVKIGMTFSGGLIDFLLFGVLPGRTAWWLVIPVGLVFAVVYYFGFRFV
IRKFNLKTPGREDEVVEQSTATGSELAQDILVGLGGSQNIKHLDACITRLRVEVKDKNQVNKDELKRLGASGVLEVGNNI
QAIFGPRSDALKSEIQAVIASGNEKKAN
>Mature_508_residues
MFKQIFGVLQKVGKALMLPVAILPAAGLLLAFGNAMQNPQLTSRAGWLTNEGVVKFAQLMEQAGGIIFSNLALLFAVGVA
IGLAGDGVAGLAAIVGFLIMNKVMGVWLELTPEVLAQGDPAYANVLGIPTLQTGVFGGIIMGLIAAWAYNKYFNIELPQF
LGFFAGKRFVPIVTAVAAVVAGFVLLLVWPPVQHGLNSFSNFMLNENRTFAAFIFGLIERSLIPFGLHHIFYSPFWFEFG
SYTDAAGNVVRGDQAIFFAQIRDGAELTAGTFMTGKFPFMMFGLPAAALAMYHEARPERKAVVGGLLASAALTSFLTGIT
EPIEFSFLFVAPLLFAVHAVFAGLSFMTMHLLNVKIGMTFSGGLIDFLLFGVLPGRTAWWLVIPVGLVFAVVYYFGFRFV
IRKFNLKTPGREDEVVEQSTATGSELAQDILVGLGGSQNIKHLDACITRLRVEVKDKNQVNKDELKRLGASGVLEVGNNI
QAIFGPRSDALKSEIQAVIASGNEKKAN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=502, Percent_Identity=48.804780876494, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1786894, Length=511, Percent_Identity=41.6829745596869, Blast_Score=344, Evalue=8e-96,
Organism=Escherichia coli, GI1787908, Length=516, Percent_Identity=38.7596899224806, Blast_Score=324, Evalue=8e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 54762; Mature: 54762

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEECCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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EEEECCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]