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The map label for this gene is ptsG [H]

Identifier: 229916496

GI number: 229916496

Start: 722126

End: 724168

Strand: Reverse

Name: ptsG [H]

Synonym: EAT1b_0766

Alternate gene names: 229916496

Gene position: 724168-722126 (Counterclockwise)

Preceding gene: 229916497

Following gene: 229916495

Centisome position: 24.14

GC content: 51.4

Gene sequence:

>2043_bases
ATGATGTGGAAGAAAGTGTTTGGCGTTTTACAACGGGTCGGGAAAGCACTCATGCTTCCGGTTGCAATCTTACCGGCAGC
CGGTCTTCTCTTGGCGTTTGGTACCGCATTCCAAAACCCGGACCTCGTTGAATTGCTCCCGTTTCTGGCGAATGACTCAC
TTGTCCTGATTTGGCAAGTCATGACAGATGCCGGGGACATCGTCTTCGCAAACTTAGGGTTGCTGTTTGCCGTCGGGGTC
GCGATCGGCCTGGCGAACGGAGATGGGGTTGCTGGTCTAGCAGCCATTGTCGGTTATTTGATCATGAACAAAGTCATCAG
CACGTGGAATGGGATTACCGCGGAAATCGCTCAAGGTGATCCGCAGTATGCGACCGTTCTCGGTATCCCGACACTCCAAA
TGGGGGTATTCGGGGGTATTATCGCAGGTCTTGTTGCAGCCTACGCATACAACAAGTATTTCAACATCAAGTTGCCAGAT
TTCTTAGGGTTCTTTGCAGGGAAGCGGTTCGTCCCGATTGCGACGGCCGCATTCAGTTTGATTATCGGGATTGCGCTCGC
ATATATATGGCCACCGATTGGGAATGCGATCAACACGTTCTCAAGTACGGTCATCGAGGCAAACGTTGCCTTATCAGCAT
TCATCTTTGGATTAGTAGAACGTTCCTTGATTCCGTTCGGTCTTCACCATATTTGGTATTCTCCATTCTGGTTCCAATTC
GGAGAGTATACGAACCAAGCCGGTGATCTCGTACAAGGTGACCAGCGGATCTTCTTCGCACAACTGCGTGACGGCGTGGA
ATTCACAGCCGGTACGTACATGACCGGGAAATTCCCGTTCATGATGTTCGGCTTACCAGCAGCCTGTCTCGCCATGTTCC
ACACGGTTCCGAAAGAACGGCGGAAAGACGTCGAGGGTCTCTATTTCTCGGCTGCCCTTACGTCATTCTTGACAGGGATC
ACAGAACCAGTCGAATTCTCATTCGTTTTCGTTGCACCACTTCTCTTCGGAATTCACGCCGTCTTTGCCGGTCTCTCCTT
CATGACGATGCATTTACTGAACGTCAAGATTGGGATGACCTTCTCTGGTGGTCTCATTGACTATCTGCTCTTCGGGGTCC
TGCCGAACCGGACGGCCTGGTGGCTCGTCATCCCGGTTGGTCTCGTCTTTGCGGTCATCTACTACTTTGGATTCCGATTC
GCTATTACGAAGTTTGACCTGAAAATTCCTGGACGTGACGTGCAGACTGGCACGAAAGGGGACAAAGCGGGGATTGGGGA
CGACTTGCCATATGAAGTGCTCGTCGGACTCGGTGGTCCTGAAAACATTAAGCATTTAGATGCATGTATCACGCGTCTCC
GTGTCACGGTGAATGATGTGAAACAAGTCGATAAAGATCTCTTAAAAGATCTTGGTGCCGCTGGTGTGCTTGAAGTGGGA
GACAATATCCAAGCCATCTTCGGACCAAAATCGGATACGCTCAAATCACAAATCGCGACCATCATCGAAGGTGGCGAATA
CAAACCGAAAGAGAAAGTAGAGAAGGCAGTCATTACACCGGAAGCGGCTGAACAAGCCGATCATCGCTTCCTCGCTCCGA
TGTCGGGTGTCCTGTTATCACTCGATGATGTGCCGGATCAAGTCTTCTCGGGTCGCATGATGGGAGAAGGATTTGCGATT
GAACCGAGCTCAGGTCAGGTCGTTTCGCCGGTGACGGGTCAAATCACGACATTCTTCCCGACGAAACATGCGATCGGTAT
TTTGGCTGACGATGGACGTGAACTGTTGATTCATGTCGGTCTCGATACGGTCAATCTGAAAGGGGAAGGATTCACGGCGA
AAGTCGAAGAAGGCGCCCGGGTCGAAGCGGGAGATGTCCTTCTTGAAGTCGATCTTAGCGCGATTCGAGATAAAGTTCCG
TCACTGATCACACCGATCATCTGGACGAACGGAGACGGAAAGGTCGTCGTCGTACCGTTCGGTGAGACGGTCGTCGCAGG
GGAAGCGCTCGACTTTAGAGCCGATGACAGAGGTCCAGAATAA

Upstream 100 bases:

>100_bases
CTTAGACCAATCCTTCGGGGTTGGTCTTTTCTTTTTATATGAAACGGTTTCATCCAAACGTTTGAGGGAAAAAGTAAGTA
TTCTGACAAAGGAGGGAACC

Downstream 100 bases:

>100_bases
CCGAGTCTCACACGCCGCTCCAGTAATGGGGCGGCTCTTCTTATGCAGTTACTTCAATGTGCCTTATTCCACAAAAGGAG
AATCCCCATTATAGTGAAGG

Product: PTS system, glucose-specific IIBC subunit

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MMWKKVFGVLQRVGKALMLPVAILPAAGLLLAFGTAFQNPDLVELLPFLANDSLVLIWQVMTDAGDIVFANLGLLFAVGV
AIGLANGDGVAGLAAIVGYLIMNKVISTWNGITAEIAQGDPQYATVLGIPTLQMGVFGGIIAGLVAAYAYNKYFNIKLPD
FLGFFAGKRFVPIATAAFSLIIGIALAYIWPPIGNAINTFSSTVIEANVALSAFIFGLVERSLIPFGLHHIWYSPFWFQF
GEYTNQAGDLVQGDQRIFFAQLRDGVEFTAGTYMTGKFPFMMFGLPAACLAMFHTVPKERRKDVEGLYFSAALTSFLTGI
TEPVEFSFVFVAPLLFGIHAVFAGLSFMTMHLLNVKIGMTFSGGLIDYLLFGVLPNRTAWWLVIPVGLVFAVIYYFGFRF
AITKFDLKIPGRDVQTGTKGDKAGIGDDLPYEVLVGLGGPENIKHLDACITRLRVTVNDVKQVDKDLLKDLGAAGVLEVG
DNIQAIFGPKSDTLKSQIATIIEGGEYKPKEKVEKAVITPEAAEQADHRFLAPMSGVLLSLDDVPDQVFSGRMMGEGFAI
EPSSGQVVSPVTGQITTFFPTKHAIGILADDGRELLIHVGLDTVNLKGEGFTAKVEEGARVEAGDVLLEVDLSAIRDKVP
SLITPIIWTNGDGKVVVVPFGETVVAGEALDFRADDRGPE

Sequences:

>Translated_680_residues
MMWKKVFGVLQRVGKALMLPVAILPAAGLLLAFGTAFQNPDLVELLPFLANDSLVLIWQVMTDAGDIVFANLGLLFAVGV
AIGLANGDGVAGLAAIVGYLIMNKVISTWNGITAEIAQGDPQYATVLGIPTLQMGVFGGIIAGLVAAYAYNKYFNIKLPD
FLGFFAGKRFVPIATAAFSLIIGIALAYIWPPIGNAINTFSSTVIEANVALSAFIFGLVERSLIPFGLHHIWYSPFWFQF
GEYTNQAGDLVQGDQRIFFAQLRDGVEFTAGTYMTGKFPFMMFGLPAACLAMFHTVPKERRKDVEGLYFSAALTSFLTGI
TEPVEFSFVFVAPLLFGIHAVFAGLSFMTMHLLNVKIGMTFSGGLIDYLLFGVLPNRTAWWLVIPVGLVFAVIYYFGFRF
AITKFDLKIPGRDVQTGTKGDKAGIGDDLPYEVLVGLGGPENIKHLDACITRLRVTVNDVKQVDKDLLKDLGAAGVLEVG
DNIQAIFGPKSDTLKSQIATIIEGGEYKPKEKVEKAVITPEAAEQADHRFLAPMSGVLLSLDDVPDQVFSGRMMGEGFAI
EPSSGQVVSPVTGQITTFFPTKHAIGILADDGRELLIHVGLDTVNLKGEGFTAKVEEGARVEAGDVLLEVDLSAIRDKVP
SLITPIIWTNGDGKVVVVPFGETVVAGEALDFRADDRGPE
>Mature_680_residues
MMWKKVFGVLQRVGKALMLPVAILPAAGLLLAFGTAFQNPDLVELLPFLANDSLVLIWQVMTDAGDIVFANLGLLFAVGV
AIGLANGDGVAGLAAIVGYLIMNKVISTWNGITAEIAQGDPQYATVLGIPTLQMGVFGGIIAGLVAAYAYNKYFNIKLPD
FLGFFAGKRFVPIATAAFSLIIGIALAYIWPPIGNAINTFSSTVIEANVALSAFIFGLVERSLIPFGLHHIWYSPFWFQF
GEYTNQAGDLVQGDQRIFFAQLRDGVEFTAGTYMTGKFPFMMFGLPAACLAMFHTVPKERRKDVEGLYFSAALTSFLTGI
TEPVEFSFVFVAPLLFGIHAVFAGLSFMTMHLLNVKIGMTFSGGLIDYLLFGVLPNRTAWWLVIPVGLVFAVIYYFGFRF
AITKFDLKIPGRDVQTGTKGDKAGIGDDLPYEVLVGLGGPENIKHLDACITRLRVTVNDVKQVDKDLLKDLGAAGVLEVG
DNIQAIFGPKSDTLKSQIATIIEGGEYKPKEKVEKAVITPEAAEQADHRFLAPMSGVLLSLDDVPDQVFSGRMMGEGFAI
EPSSGQVVSPVTGQITTFFPTKHAIGILADDGRELLIHVGLDTVNLKGEGFTAKVEEGARVEAGDVLLEVDLSAIRDKVP
SLITPIIWTNGDGKVVVVPFGETVVAGEALDFRADDRGPE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=667, Percent_Identity=39.880059970015, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1787343, Length=502, Percent_Identity=47.0119521912351, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787908, Length=515, Percent_Identity=36.6990291262136, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1788757, Length=155, Percent_Identity=38.7096774193548, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1790159, Length=163, Percent_Identity=42.9447852760736, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73256; Mature: 73256

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMWKKVFGVLQRVGKALMLPVAILPAAGLLLAFGTAFQNPDLVELLPFLANDSLVLIWQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEE
MTDAGDIVFANLGLLFAVGVAIGLANGDGVAGLAAIVGYLIMNKVISTWNGITAEIAQGD
HHCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PQYATVLGIPTLQMGVFGGIIAGLVAAYAYNKYFNIKLPDFLGFFAGKRFVPIATAAFSL
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCEEHHHHHHHHH
IIGIALAYIWPPIGNAINTFSSTVIEANVALSAFIFGLVERSLIPFGLHHIWYSPFWFQF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GEYTNQAGDLVQGDQRIFFAQLRDGVEFTAGTYMTGKFPFMMFGLPAACLAMFHTVPKER
HHHCCCCCCCCCCCCCEEEEHHHCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHCCHHH
RKDVEGLYFSAALTSFLTGITEPVEFSFVFVAPLLFGIHAVFAGLSFMTMHLLNVKIGMT
HCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
FSGGLIDYLLFGVLPNRTAWWLVIPVGLVFAVIYYFGFRFAITKFDLKIPGRDVQTGTKG
ECCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCC
DKAGIGDDLPYEVLVGLGGPENIKHLDACITRLRVTVNDVKQVDKDLLKDLGAAGVLEVG
CCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
DNIQAIFGPKSDTLKSQIATIIEGGEYKPKEKVEKAVITPEAAEQADHRFLAPMSGVLLS
CCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHCCCEECCCHHHHEEE
LDDVPDQVFSGRMMGEGFAIEPSSGQVVSPVTGQITTFFPTKHAIGILADDGRELLIHVG
ECCCCHHHHCCCCCCCCEEECCCCCCEECCCCCCEEEEECCCCEEEEEECCCCEEEEEEC
LDTVNLKGEGFTAKVEEGARVEAGDVLLEVDLSAIRDKVPSLITPIIWTNGDGKVVVVPF
CEEEEECCCCCEEECCCCCEEECCCEEEEECHHHHHHHHHHHHCCEEEECCCCEEEEEEC
GETVVAGEALDFRADDRGPE
CCEEEECCCEECCCCCCCCC
>Mature Secondary Structure
MMWKKVFGVLQRVGKALMLPVAILPAAGLLLAFGTAFQNPDLVELLPFLANDSLVLIWQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEE
MTDAGDIVFANLGLLFAVGVAIGLANGDGVAGLAAIVGYLIMNKVISTWNGITAEIAQGD
HHCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
PQYATVLGIPTLQMGVFGGIIAGLVAAYAYNKYFNIKLPDFLGFFAGKRFVPIATAAFSL
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCEEHHHHHHHHH
IIGIALAYIWPPIGNAINTFSSTVIEANVALSAFIFGLVERSLIPFGLHHIWYSPFWFQF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GEYTNQAGDLVQGDQRIFFAQLRDGVEFTAGTYMTGKFPFMMFGLPAACLAMFHTVPKER
HHHCCCCCCCCCCCCCEEEEHHHCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHCCHHH
RKDVEGLYFSAALTSFLTGITEPVEFSFVFVAPLLFGIHAVFAGLSFMTMHLLNVKIGMT
HCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
FSGGLIDYLLFGVLPNRTAWWLVIPVGLVFAVIYYFGFRFAITKFDLKIPGRDVQTGTKG
ECCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCC
DKAGIGDDLPYEVLVGLGGPENIKHLDACITRLRVTVNDVKQVDKDLLKDLGAAGVLEVG
CCCCCCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
DNIQAIFGPKSDTLKSQIATIIEGGEYKPKEKVEKAVITPEAAEQADHRFLAPMSGVLLS
CCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHCCCEECCCHHHHEEE
LDDVPDQVFSGRMMGEGFAIEPSSGQVVSPVTGQITTFFPTKHAIGILADDGRELLIHVG
ECCCCHHHHCCCCCCCCEEECCCCCCEECCCCCCEEEEECCCCEEEEEECCCCEEEEEEC
LDTVNLKGEGFTAKVEEGARVEAGDVLLEVDLSAIRDKVPSLITPIIWTNGDGKVVVVPF
CEEEEECCCCCEEECCCCCEEECCCEEEEECHHHHHHHHHHHHCCEEEECCCCEEEEEEC
GETVVAGEALDFRADDRGPE
CCEEEECCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]