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The map label for this gene is nrdR

Identifier: 229916385

GI number: 229916385

Start: 606964

End: 607431

Strand: Reverse

Name: nrdR

Synonym: EAT1b_0655

Alternate gene names: 229916385

Gene position: 607431-606964 (Counterclockwise)

Preceding gene: 229916386

Following gene: 229916384

Centisome position: 20.25

GC content: 47.65

Gene sequence:

>468_bases
ATGCGTTGTCCGAAATGTGATCATAATGGAACGAGAGTGCTCGATTCCCGTCCGGTGCAAGACCATTATTCGATTCGACG
TCGTCGTGAATGTGAAAAATGTGGGTATCGGTTTACAACGTTTGAGACGGTCGAACAGACACCGCTCATCATTGTCAAAA
AAGATGGAAATCGCGAAGAGTTCAGTCGTGAAAAAGTGCTTCGCGGCATTATTCGGGCGTGCGAGAAACGACCGGTCACA
CTTGAACAGCTCGAAGGGGTTGTGACGAAAGTCGAACAGCAACTCCGTGCCCTCGCCCAGTCAGAGATTCCGAGTGAACA
AGTAGGTGAGCTCGTGATGAACGAGCTCGCGCGAGTCGATGAAGTCGCATATGTCCGTTTCGCATCGGTTTATCGTCAAT
TCAAAGACATCACGGTGTTCTTTAAAGAACTCGAAGATTTAATGAAGCAAGAAAATTCGACCAACTAA

Upstream 100 bases:

>100_bases
CCTCTCACAAATTGTATCGCACTACTACGAGGCACTCACGCAACAATTCCCGCTACGTGCTATTGGAAATAAAACAGTCG
AACGATAAGGAGGTTTGAGC

Downstream 100 bases:

>100_bases
AGGGCGGCCTGCTGGTCGCCCTTTTTCAAGGGAGAGAGCCATGGAGAAAGAACGTACAATCTTTGGGACGGACGAATTGT
TAATCATGAGTACCGGTCTT

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRCPKCDHNGTRVLDSRPVQDHYSIRRRRECEKCGYRFTTFETVEQTPLIIVKKDGNREEFSREKVLRGIIRACEKRPVT
LEQLEGVVTKVEQQLRALAQSEIPSEQVGELVMNELARVDEVAYVRFASVYRQFKDITVFFKELEDLMKQENSTN

Sequences:

>Translated_155_residues
MRCPKCDHNGTRVLDSRPVQDHYSIRRRRECEKCGYRFTTFETVEQTPLIIVKKDGNREEFSREKVLRGIIRACEKRPVT
LEQLEGVVTKVEQQLRALAQSEIPSEQVGELVMNELARVDEVAYVRFASVYRQFKDITVFFKELEDLMKQENSTN
>Mature_155_residues
MRCPKCDHNGTRVLDSRPVQDHYSIRRRRECEKCGYRFTTFETVEQTPLIIVKKDGNREEFSREKVLRGIIRACEKRPVT
LEQLEGVVTKVEQQLRALAQSEIPSEQVGELVMNELARVDEVAYVRFASVYRQFKDITVFFKELEDLMKQENSTN

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=46.9387755102041, Blast_Score=137, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_EXISA (C4L464)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002885031.1
- GeneID:   7871427
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0655
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18201; Mature: 18201

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPKCDHNGTRVLDSRPVQDHYSIRRRRECEKCGYRFTTFETVEQTPLIIVKKDGNREE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCHHH
FSREKVLRGIIRACEKRPVTLEQLEGVVTKVEQQLRALAQSEIPSEQVGELVMNELARVD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFKDITVFFKELEDLMKQENSTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRCPKCDHNGTRVLDSRPVQDHYSIRRRRECEKCGYRFTTFETVEQTPLIIVKKDGNREE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCHHH
FSREKVLRGIIRACEKRPVTLEQLEGVVTKVEQQLRALAQSEIPSEQVGELVMNELARVD
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EVAYVRFASVYRQFKDITVFFKELEDLMKQENSTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA