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The map label for this gene is deoC

Identifier: 229916336

GI number: 229916336

Start: 555918

End: 556583

Strand: Reverse

Name: deoC

Synonym: EAT1b_0606

Alternate gene names: 229916336

Gene position: 556583-555918 (Counterclockwise)

Preceding gene: 229916337

Following gene: 229916335

Centisome position: 18.55

GC content: 48.05

Gene sequence:

>666_bases
ATGGAATTAGCCCGTTATATCGACCACACAGCTTTAAAGGCTGAAACAACAAAAGATCAAATTACAACACTTTGTGCAGA
GGCGCTCGAATACAAATTCGCAAGCGTTTGTGTCAACCCGACATGGGTCAAATATGCAGCAGAACAACTCAAGTCCGATG
ATGATGTCAAAGTATGTACTGTCATCGGTTTCCCACTTGGAGCAAACACACCTGAGGTAAAAGCATTCGAAACAAAAGAT
GCGATTGCCAATGGCGCAGATGAAGTAGATATGGTCATCAACATCGCAGCACTCAAAGATGCTGACTACGATCTCGTAGA
ACGTGACATCCGTGCGGTTGTCGAAGCGGCAAACGGTACACTCGTCAAAGTCATCTTTGAAACATGCATGCTTACAAAAG
AAGAAATCAAGAAAGCTGCCGAACTTTCAGTGAAAGCTGGAGCAGACTTCGTCAAAACTTCGACTGGTTTCTCGACAGGT
GGCGCGACAGTCGAAGACATTCGCCTCATGCGCGAGACGGTCGGACCTGACATCGGCGTAAAAGCTTCAGGTGGTGTCCG
TGACTTCGAGGGTGCGAAAGCGATGATCGATGCCGGTGCGACACGTATCGGTGCTTCAGCGGGTATCGCGATTGTCACTG
GTGGACGTTCAGACAGCGACTATTAA

Upstream 100 bases:

>100_bases
AAACGTCGTCAGTTGATTTAGGTTTGAAAGCTGTTACATCTCGAAAAAACATGGTAATATGTTAGATGTCAGACTTATTT
GTCAGAGGAGGAAATGAATA

Downstream 100 bases:

>100_bases
TAAGTGGTTGACCACACGACTTAATTTCACTATAATATGATATGACGTGTGAAACACGTTTCCTTAGTCGTGTAATTCGG
AGGGAGGGAAAACTAGTGGA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MELARYIDHTALKAETTKDQITTLCAEALEYKFASVCVNPTWVKYAAEQLKSDDDVKVCTVIGFPLGANTPEVKAFETKD
AIANGADEVDMVINIAALKDADYDLVERDIRAVVEAANGTLVKVIFETCMLTKEEIKKAAELSVKAGADFVKTSTGFSTG
GATVEDIRLMRETVGPDIGVKASGGVRDFEGAKAMIDAGATRIGASAGIAIVTGGRSDSDY

Sequences:

>Translated_221_residues
MELARYIDHTALKAETTKDQITTLCAEALEYKFASVCVNPTWVKYAAEQLKSDDDVKVCTVIGFPLGANTPEVKAFETKD
AIANGADEVDMVINIAALKDADYDLVERDIRAVVEAANGTLVKVIFETCMLTKEEIKKAAELSVKAGADFVKTSTGFSTG
GATVEDIRLMRETVGPDIGVKASGGVRDFEGAKAMIDAGATRIGASAGIAIVTGGRSDSDY
>Mature_221_residues
MELARYIDHTALKAETTKDQITTLCAEALEYKFASVCVNPTWVKYAAEQLKSDDDVKVCTVIGFPLGANTPEVKAFETKD
AIANGADEVDMVINIAALKDADYDLVERDIRAVVEAANGTLVKVIFETCMLTKEEIKKAAELSVKAGADFVKTSTGFSTG
GATVEDIRLMRETVGPDIGVKASGGVRDFEGAKAMIDAGATRIGASAGIAIVTGGRSDSDY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=218, Percent_Identity=30.2752293577982, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790841, Length=206, Percent_Identity=36.8932038834951, Blast_Score=100, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17533015, Length=209, Percent_Identity=29.6650717703349, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_EXISA (C4L415)

Other databases:

- EMBL:   CP001615
- RefSeq:   YP_002884982.1
- ProteinModelPortal:   C4L415
- GeneID:   7871345
- GenomeReviews:   CP001615_GR
- KEGG:   eat:EAT1b_0606
- OMA:   GANTPEV
- ProtClustDB:   CLSK2489132
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23425; Mature: 23425

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: ACT_SITE 152-152 ACT_SITE 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELARYIDHTALKAETTKDQITTLCAEALEYKFASVCVNPTWVKYAAEQLKSDDDVKVCT
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEE
VIGFPLGANTPEVKAFETKDAIANGADEVDMVINIAALKDADYDLVERDIRAVVEAANGT
EEECCCCCCCCCCEEEECHHHHHCCCCCHHHEEEEEHHCCCCHHHHHHHHHHHHHHCCCC
LVKVIFETCMLTKEEIKKAAELSVKAGADFVKTSTGFSTGGATVEDIRLMRETVGPDIGV
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
KASGGVRDFEGAKAMIDAGATRIGASAGIAIVTGGRSDSDY
CCCCCCCCCCCHHHHHHCCCHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MELARYIDHTALKAETTKDQITTLCAEALEYKFASVCVNPTWVKYAAEQLKSDDDVKVCT
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEE
VIGFPLGANTPEVKAFETKDAIANGADEVDMVINIAALKDADYDLVERDIRAVVEAANGT
EEECCCCCCCCCCEEEECHHHHHCCCCCHHHEEEEEHHCCCCHHHHHHHHHHHHHHCCCC
LVKVIFETCMLTKEEIKKAAELSVKAGADFVKTSTGFSTGGATVEDIRLMRETVGPDIGV
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
KASGGVRDFEGAKAMIDAGATRIGASAGIAIVTGGRSDSDY
CCCCCCCCCCCHHHHHHCCCHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA