BacMap

Definition	Exiguobacterium sp. AT1b, complete genome.
Accession	NC_012673
Length	2,999,895

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The map label for this gene is yqjQ [H]

Identifier: 229916212

GI number: 229916212

Start: 440473

End: 441267

Strand: Direct

Name: yqjQ [H]

Synonym: EAT1b_0481

Alternate gene names: 229916212

Gene position: 440473-441267 (Clockwise)

Preceding gene: 229916208

Following gene: 229916220

Centisome position: 14.68

GC content: 50.69

Gene sequence:

>795_bases
ATGTTGTCAAAGACAGCTTTAATCACCGGCGCCTCGATGGGCATCGGTCTAGACTTGGCCGTACTCGCCGCTCGCGATGG
CTATGACTGTATTTTAGTATCTCGGAACGAACCACGATTGCATGAACTAAAAAAAGTACTCGAGACGCGTTATCGCATCA
ATGTCCATATCTTTGCACTAGATTTGGCAAAACATGACGCCGCAGTCCGATTGACGACGATGATCGCCGAAGCTGGCCTC
ACTGTCGACTTTTTAATCAACAATGCCGGGTTCGGCACGTCCGGCGCATTCGCCGACCTCGATGCCGAGACGGAGGCCGA
CGAGGTCCGATTGAATGTCAATACGTTGACCGAACTGACGAAAGCCTATTTGCCTGACATGCTCGAACGTGACCACGGAT
TTGTGTTGAACGTCGCATCCGTCGCTGCCTTCCAACCTGGTCCATATATGGCCGTCTATTATGCAACGAAAGCCTATGTC
CTTTCATTCACTGAAGCGATTCATGCCGAAGTGAAAGGTAGCGGTGTGCATGTGAGTGTATTATGCCCTGGCCCGACGGA
TACAAATTTCTTTAATCGTGCCGGGAGTGAATTGTCGTTCTCGAAAATGCCATCTCATCTCGTCGCTTTCTTCGGATACA
AAGGGGTGATGAATAACAAGCGTGTGATCATCCCCGGACTCTCGAATCAGCTGTTGGTCGGGGTCGCCAAATTGATGCCG
AGAGCTCTCAGTTTAGAAGTATTACGCCGCGTCCAGAAACCGGCTGATGGAACACCTGCTGAATCGACCACATGA

Upstream 100 bases:

>100_bases
TATACTTTAGCATATGTTTCAATGTGCGAACGAAGCAGGATTTTAACAACTCGTGAAGAATTCAGTAACAATGTATGACT
TTTCATCAAAGGAGTGGATC

Downstream 100 bases:

>100_bases
AAAGGAGCGACCGCATCGGGTCGCTCCTTTTATGGTTCAGAGTGTAAGCGAGAGACGTTCACAAGCCGATATAGAAACAC
ACCTGCCGGAATCATAGTCA

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLSKTALITGASMGIGLDLAVLAARDGYDCILVSRNEPRLHELKKVLETRYRINVHIFALDLAKHDAAVRLTTMIAEAGL
TVDFLINNAGFGTSGAFADLDAETEADEVRLNVNTLTELTKAYLPDMLERDHGFVLNVASVAAFQPGPYMAVYYATKAYV
LSFTEAIHAEVKGSGVHVSVLCPGPTDTNFFNRAGSELSFSKMPSHLVAFFGYKGVMNNKRVIIPGLSNQLLVGVAKLMP
RALSLEVLRRVQKPADGTPAESTT

Sequences:

>Translated_264_residues
MLSKTALITGASMGIGLDLAVLAARDGYDCILVSRNEPRLHELKKVLETRYRINVHIFALDLAKHDAAVRLTTMIAEAGL
TVDFLINNAGFGTSGAFADLDAETEADEVRLNVNTLTELTKAYLPDMLERDHGFVLNVASVAAFQPGPYMAVYYATKAYV
LSFTEAIHAEVKGSGVHVSVLCPGPTDTNFFNRAGSELSFSKMPSHLVAFFGYKGVMNNKRVIIPGLSNQLLVGVAKLMP
RALSLEVLRRVQKPADGTPAESTT
>Mature_264_residues
MLSKTALITGASMGIGLDLAVLAARDGYDCILVSRNEPRLHELKKVLETRYRINVHIFALDLAKHDAAVRLTTMIAEAGL
TVDFLINNAGFGTSGAFADLDAETEADEVRLNVNTLTELTKAYLPDMLERDHGFVLNVASVAAFQPGPYMAVYYATKAYV
LSFTEAIHAEVKGSGVHVSVLCPGPTDTNFFNRAGSELSFSKMPSHLVAFFGYKGVMNNKRVIIPGLSNQLLVGVAKLMP
RALSLEVLRRVQKPADGTPAESTT

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=186, Percent_Identity=29.5698924731183, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI226371731, Length=211, Percent_Identity=27.4881516587678, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4557649, Length=190, Percent_Identity=28.9473684210526, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=30.8900523560209, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=30.9278350515464, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI66933014, Length=166, Percent_Identity=30.7228915662651, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=191, Percent_Identity=27.7486910994764, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI210032110, Length=250, Percent_Identity=25.2, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7657478, Length=204, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI142976729, Length=251, Percent_Identity=29.0836653386454, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503817, Length=193, Percent_Identity=33.160621761658, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI223718074, Length=199, Percent_Identity=30.1507537688442, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40254992, Length=190, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI210032112, Length=175, Percent_Identity=27.4285714285714, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=26.3736263736264, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=32.2222222222222, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=32.0855614973262, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=27.8350515463918, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=188, Percent_Identity=29.2553191489362, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=25, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=33.5051546391753, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=197, Percent_Identity=31.9796954314721, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25152911, Length=185, Percent_Identity=32.972972972973, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=218, Percent_Identity=27.9816513761468, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560176, Length=189, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=201, Percent_Identity=30.3482587064677, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=203, Percent_Identity=28.0788177339901, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=203, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=236, Percent_Identity=29.6610169491525, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=231, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=28.2722513089005, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=28.2722513089005, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=233, Percent_Identity=27.4678111587983, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17557668, Length=201, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI212646214, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=194, Percent_Identity=30.4123711340206, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=199, Percent_Identity=29.6482412060301, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=204, Percent_Identity=28.921568627451, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=200, Percent_Identity=28, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=204, Percent_Identity=27.9411764705882, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=202, Percent_Identity=29.7029702970297, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319635, Length=192, Percent_Identity=27.6041666666667, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI161076933, Length=188, Percent_Identity=32.4468085106383, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584748, Length=188, Percent_Identity=32.4468085106383, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=31.5508021390374, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=31.5508021390374, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=30.6122448979592, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=35.5670103092784, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358495, Length=208, Percent_Identity=31.25, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24584752, Length=192, Percent_Identity=29.6875, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28571526, Length=204, Percent_Identity=28.921568627451, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355631, Length=244, Percent_Identity=25.8196721311475, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24580925, Length=208, Percent_Identity=27.8846153846154, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=207, Percent_Identity=29.951690821256, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639444, Length=194, Percent_Identity=30.9278350515464, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=23.3830845771144, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356301, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28545; Mature: 28545

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKTALITGASMGIGLDLAVLAARDGYDCILVSRNEPRLHELKKVLETRYRINVHIFAL
CCCCCEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHEEEEEEEEEE
DLAKHDAAVRLTTMIAEAGLTVDFLINNAGFGTSGAFADLDAETEADEVRLNVNTLTELT
EECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEECCCCCCCCCCEEEEHHHHHHHH
KAYLPDMLERDHGFVLNVASVAAFQPGPYMAVYYATKAYVLSFTEAIHAEVKGSGVHVSV
HHHHHHHHHCCCCEEEEEHHHHEECCCCEEEEEEEHHHHHHHHHHHHHHEECCCCEEEEE
LCPGPTDTNFFNRAGSELSFSKMPSHLVAFFGYKGVMNNKRVIIPGLSNQLLVGVAKLMP
EECCCCCCCHHHCCCCCCCHHHCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCC
RALSLEVLRRVQKPADGTPAESTT
HHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLSKTALITGASMGIGLDLAVLAARDGYDCILVSRNEPRLHELKKVLETRYRINVHIFAL
CCCCCEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHEEEEEEEEEE
DLAKHDAAVRLTTMIAEAGLTVDFLINNAGFGTSGAFADLDAETEADEVRLNVNTLTELT
EECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEECCCCCCCCCCEEEEHHHHHHHH
KAYLPDMLERDHGFVLNVASVAAFQPGPYMAVYYATKAYVLSFTEAIHAEVKGSGVHVSV
HHHHHHHHHCCCCEEEEEHHHHEECCCCEEEEEEEHHHHHHHHHHHHHHEECCCCEEEEE
LCPGPTDTNFFNRAGSELSFSKMPSHLVAFFGYKGVMNNKRVIIPGLSNQLLVGVAKLMP
EECCCCCCCHHHCCCCCCCHHHCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCC
RALSLEVLRRVQKPADGTPAESTT
HHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]