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The map label for this gene is cheV [H]

Identifier: 229916202

GI number: 229916202

Start: 429636

End: 430517

Strand: Direct

Name: cheV [H]

Synonym: EAT1b_0471

Alternate gene names: 229916202

Gene position: 429636-430517 (Clockwise)

Preceding gene: 229916192

Following gene: 229916204

Centisome position: 14.32

GC content: 49.09

Gene sequence:

>882_bases
TTGAGCACTGATCATAATATTTTACTTGAAGCAGGAACGAACGAACTTGAAATCGTGATTTTCCAAGCTGGACCGTTCTT
GTTCGGCATCAATGTCATGAAAGTACGTGAAATTATCACGATGCTTCCATTGACGCCACTCCCAGGTACACCGGAAGCCA
TCATGGGGTTAATCGAGTTGCGCGGTGAGGTCATGACCGTGATCGACCTTCCGATGGTCATCAGCCATCCGCGTGAAGTC
GGAAGTGATGATCGTTTGATTGTCTGCGAGTTCAACGGTGAGAAGTCGGTTCTTCGGGTCGACCAGGTGACCGAGATCAA
ACGCATCTCTTGGGAGCAAATTGACACGCCGTCCGATCTCGCACGTGGCGTTCAAGGCATCACGAACGGTGTCGTCAAAA
CAGGTGACCAGATGATCATCTTGCTCGACTACGAGCGAATCGCGCTCGAATTGTCACGTAAAGACATCATGGCTCGCGAA
TCTGTGAAGCGACTCGGTGCTCGTGAGCGCTCGAACAAAAATATTTGGATCGCTGAAGATTCAGAGATGCTCCGCACACT
GATTCTCGATACGTTGGATGATGCGGGGTACTTCAATACAACAGTCTTCAATAACGGGAAAGAGGCACTCGATGCGTTTG
AACAAGAAGGCGTCGAATGCGACCTCCTCATCACCGATATTGAGATGCCACAGATGGATGGACTTCATTTGACGAAGCGA
CTCCGTGAGATGGACCGCTATGCAACACTTCCAATCATCATCTTCTCGTCACTCATCTCGGATGACTTGAAACATAAAGG
GGAAGCCGTCGGTGCGAACGCTCAAATCACGAAACCAGAAATCGGAATGTTGATTGCGACGCTCGATGAATTTGTAGGAT
AA

Upstream 100 bases:

>100_bases
TTTGTGAATTCTGATGAGAGTTGACACTATTTTTACTGTAGATTTATCGATCGGATACCGATAGTAAAGATGAGAGTACG
TGAAATAGGAGGGACTACCA

Downstream 100 bases:

>100_bases
TAAAAAAGTTTGCGACATCTCCGTCGCAAACTTTTTTATGTGAATTGTTCGAAATGCGTATTCCACTCGCTTAAAAATCG
CTTACTATGCGATTCGATGG

Product: response regulator receiver modulated CheW protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSTDHNILLEAGTNELEIVIFQAGPFLFGINVMKVREIITMLPLTPLPGTPEAIMGLIELRGEVMTVIDLPMVISHPREV
GSDDRLIVCEFNGEKSVLRVDQVTEIKRISWEQIDTPSDLARGVQGITNGVVKTGDQMIILLDYERIALELSRKDIMARE
SVKRLGARERSNKNIWIAEDSEMLRTLILDTLDDAGYFNTTVFNNGKEALDAFEQEGVECDLLITDIEMPQMDGLHLTKR
LREMDRYATLPIIIFSSLISDDLKHKGEAVGANAQITKPEIGMLIATLDEFVG

Sequences:

>Translated_293_residues
MSTDHNILLEAGTNELEIVIFQAGPFLFGINVMKVREIITMLPLTPLPGTPEAIMGLIELRGEVMTVIDLPMVISHPREV
GSDDRLIVCEFNGEKSVLRVDQVTEIKRISWEQIDTPSDLARGVQGITNGVVKTGDQMIILLDYERIALELSRKDIMARE
SVKRLGARERSNKNIWIAEDSEMLRTLILDTLDDAGYFNTTVFNNGKEALDAFEQEGVECDLLITDIEMPQMDGLHLTKR
LREMDRYATLPIIIFSSLISDDLKHKGEAVGANAQITKPEIGMLIATLDEFVG
>Mature_292_residues
STDHNILLEAGTNELEIVIFQAGPFLFGINVMKVREIITMLPLTPLPGTPEAIMGLIELRGEVMTVIDLPMVISHPREVG
SDDRLIVCEFNGEKSVLRVDQVTEIKRISWEQIDTPSDLARGVQGITNGVVKTGDQMIILLDYERIALELSRKDIMARES
VKRLGARERSNKNIWIAEDSEMLRTLILDTLDDAGYFNTTVFNNGKEALDAFEQEGVECDLLITDIEMPQMDGLHLTKRL
REMDRYATLPIIIFSSLISDDLKHKGEAVGANAQITKPEIGMLIATLDEFVG

Specific function: Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW function together to couple CheA activation to methyl-accepting chemotaxis protein receptor status and possible CheA-dependent phosphoryl

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 32739; Mature: 32608

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS50851 CHEW ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDHNILLEAGTNELEIVIFQAGPFLFGINVMKVREIITMLPLTPLPGTPEAIMGLIEL
CCCCCCEEEEECCCCEEEEEEECCCEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RGEVMTVIDLPMVISHPREVGSDDRLIVCEFNGEKSVLRVDQVTEIKRISWEQIDTPSDL
CCCEEEEEECCHHHCCCHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHCCHHHCCCHHHH
ARGVQGITNGVVKTGDQMIILLDYERIALELSRKDIMARESVKRLGARERSNKNIWIAED
HHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECH
SEMLRTLILDTLDDAGYFNTTVFNNGKEALDAFEQEGVECDLLITDIEMPQMDGLHLTKR
HHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHH
LREMDRYATLPIIIFSSLISDDLKHKGEAVGANAQITKPEIGMLIATLDEFVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
STDHNILLEAGTNELEIVIFQAGPFLFGINVMKVREIITMLPLTPLPGTPEAIMGLIEL
CCCCCEEEEECCCCEEEEEEECCCEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RGEVMTVIDLPMVISHPREVGSDDRLIVCEFNGEKSVLRVDQVTEIKRISWEQIDTPSDL
CCCEEEEEECCHHHCCCHHCCCCCCEEEEEECCCCCEEEHHHHHHHHHCCHHHCCCHHHH
ARGVQGITNGVVKTGDQMIILLDYERIALELSRKDIMARESVKRLGARERSNKNIWIAED
HHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECH
SEMLRTLILDTLDDAGYFNTTVFNNGKEALDAFEQEGVECDLLITDIEMPQMDGLHLTKR
HHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHH
LREMDRYATLPIIIFSSLISDDLKHKGEAVGANAQITKPEIGMLIATLDEFVG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8169223; 9384377; 8169224 [H]