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The map label for this gene is ccdA [H]

Identifier: 229916130

GI number: 229916130

Start: 362926

End: 363624

Strand: Reverse

Name: ccdA [H]

Synonym: EAT1b_0399

Alternate gene names: 229916130

Gene position: 363624-362926 (Counterclockwise)

Preceding gene: 229916132

Following gene: 229916129

Centisome position: 12.12

GC content: 46.35

Gene sequence:

>699_bases
ATGGAAGTCACATTATGGCTCGCATTTGGGGCGGGCGTCTTATCGTTCTTGTCACCATGTACGCTCCCGTTGTATCCGGT
CTTTCTCTCGTATATCACTGGGGTTTCCGTATCTGAGTTAAAAAATGAAGGATTAAAACAGCGTACAGCTTGGTTCCACA
CATTTTCGTTCTTATTCGGTTTTTCGATTGTCTTTCTTGTGCTAGGGTTGTCGACTTCGTTGATCGCAGACGTCTTCATC
CAATACAAGGACAGTCTACGCATGTTCGGCGCCATTTTGATTTTCGTATTCGGCGTCTTTTTGGCGGGCTTATGGCAACC
GCAATTTATGATGCGTGAAAAGAAAATGGATATCGGCGAACGAAAGAGCGGTTATTTTGGAACCGTTTTAATTGGTATTG
GATTTGCGGCCGGTTGGACACCGTGTACAGGTCCGATTTTAGCTGGTGTGATCGCACTAGCCGCTACGAACCCGAGTCAA
GGACTCGGCTATATGTTGGCGTATGTCATCGGGTTTGCGATTCCATTTTTGGTGATGGTCGCATTCGTTGGCAAGATCAA
GTACTTAGCACGCAACAGTGCAAAAGTGGCAAAAGTCGGAGGCTATTTGATGATGGCGTTCGGCGTACTATTATATTTTG
ACGGAATGAATCGGTTCGCTGCATGGATGAGCGAGCTTGTCGGATTCACCGGATTTTAA

Upstream 100 bases:

>100_bases
CCATTTCAAAAATTACAAAATGATGTTGAGGTTTGAAAGAAAAGATTCGAGCAATTTAAATAGGATTTCGCTATAATGGT
CGTGAAAGGTGGAAATCGTC

Downstream 100 bases:

>100_bases
GGGGTTGACCGAGATGTCAATGTTATGGGGGTCGACTCTCGTTGCGTTGTTAATGGGTATCGTAGCGAGCTTTGTTCGTG
TAAAAGCATCGGCAAAGCCG

Product: cytochrome c biogenesis protein transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MEVTLWLAFGAGVLSFLSPCTLPLYPVFLSYITGVSVSELKNEGLKQRTAWFHTFSFLFGFSIVFLVLGLSTSLIADVFI
QYKDSLRMFGAILIFVFGVFLAGLWQPQFMMREKKMDIGERKSGYFGTVLIGIGFAAGWTPCTGPILAGVIALAATNPSQ
GLGYMLAYVIGFAIPFLVMVAFVGKIKYLARNSAKVAKVGGYLMMAFGVLLYFDGMNRFAAWMSELVGFTGF

Sequences:

>Translated_232_residues
MEVTLWLAFGAGVLSFLSPCTLPLYPVFLSYITGVSVSELKNEGLKQRTAWFHTFSFLFGFSIVFLVLGLSTSLIADVFI
QYKDSLRMFGAILIFVFGVFLAGLWQPQFMMREKKMDIGERKSGYFGTVLIGIGFAAGWTPCTGPILAGVIALAATNPSQ
GLGYMLAYVIGFAIPFLVMVAFVGKIKYLARNSAKVAKVGGYLMMAFGVLLYFDGMNRFAAWMSELVGFTGF
>Mature_232_residues
MEVTLWLAFGAGVLSFLSPCTLPLYPVFLSYITGVSVSELKNEGLKQRTAWFHTFSFLFGFSIVFLVLGLSTSLIADVFI
QYKDSLRMFGAILIFVFGVFLAGLWQPQFMMREKKMDIGERKSGYFGTVLIGIGFAAGWTPCTGPILAGVIALAATNPSQ
GLGYMLAYVIGFAIPFLVMVAFVGKIKYLARNSAKVAKVGGYLMMAFGVLLYFDGMNRFAAWMSELVGFTGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 25425; Mature: 25425

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTLWLAFGAGVLSFLSPCTLPLYPVFLSYITGVSVSELKNEGLKQRTAWFHTFSFLFG
CCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
FSIVFLVLGLSTSLIADVFIQYKDSLRMFGAILIFVFGVFLAGLWQPQFMMREKKMDIGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
RKSGYFGTVLIGIGFAAGWTPCTGPILAGVIALAATNPSQGLGYMLAYVIGFAIPFLVMV
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AFVGKIKYLARNSAKVAKVGGYLMMAFGVLLYFDGMNRFAAWMSELVGFTGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEVTLWLAFGAGVLSFLSPCTLPLYPVFLSYITGVSVSELKNEGLKQRTAWFHTFSFLFG
CCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHH
FSIVFLVLGLSTSLIADVFIQYKDSLRMFGAILIFVFGVFLAGLWQPQFMMREKKMDIGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
RKSGYFGTVLIGIGFAAGWTPCTGPILAGVIALAATNPSQGLGYMLAYVIGFAIPFLVMV
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AFVGKIKYLARNSAKVAKVGGYLMMAFGVLLYFDGMNRFAAWMSELVGFTGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]