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The map label for this gene is ywcA [H]

Identifier: 229916128

GI number: 229916128

Start: 360860

End: 362419

Strand: Direct

Name: ywcA [H]

Synonym: EAT1b_0397

Alternate gene names: 229916128

Gene position: 360860-362419 (Clockwise)

Preceding gene: 229916127

Following gene: 229916131

Centisome position: 12.03

GC content: 51.79

Gene sequence:

>1560_bases
ATGAACTGGACCGCAATCGCCCTCTTTATCGCCATTGTCGGACTCACGCTTGTGATTACATACTTTGCAGCACGAAAAAC
AAAAACTGCCAGTGACTTTTATACGGCAGACGGTGGATTGACCGGATTTCAAAACGGTCTTGCCATTGCAGGGGACTATA
TGTCTGCCGCATCGTTTCTCGGAATTGCGGGCATGATCGCGCTCGCGGGATTCGATGGATTTTTCTATTCTATCGGTTTC
CTCGTCGCCTACCTCGTGGTCCTCTATCTCGTCGCCGAACCATTACGTAATCTTGGGAAATATACGATGGCAGATATGAT
CGCGGCACGTTTCAACAAGCCCCGCGTTCGTGGTGTCGCAGCGATGAATGCGATTGTCATCTCCATTTTCTACATGATTG
CGCAACTCGTCGGAGCGGGTGCTCTGATTGAATTGTTACTCGGAATCCCTTATACGACAAGTGTCGTCGTCGTCGGTATC
TTGATGACGGTCTACGTCGTTTTCGGTGGCATGACGGCCACTTCTTGGGTACAAATCACGAAAGCCGTACTTTTAATGAT
TGGGACGGCAATCATCTCATTTCTCGTGTTCGCTCGTTTTGATTTCTCCGTCACGACAATGTTCAATGAAGTCAGCAAAG
CGACCCCACTCGGAAGTGACTTCTTGAACCCAGGGAATAAATTCAAGCTACCGCTCGATACTATCTCATTAAACATGGCG
CTCGTGCTCGGTACGGCAGGGCTCCCTCATATTCTGATTCGCTTCTTCACCGTCAAAGACGCACCGACTGCTCGGCAATC
CGTCGTCTATGCGACATGGATCATCGGTGCATTTTATATCTTGACCATATTCCTAGGTTTCGGTGCCGCAGCATTCGTCG
GACGTGATGCCATTCTCGCCGCAAACCCAGCCGGCAACATGGCGGCCCCTCTTCTCGCGCAAGTGCTCGGTGGTGACCTC
TTGTTCGCTTTCGTTGCCGCAATCGCGTTCGCGACAATTCTTGCCGTTGTAGCAGGACTCGTACTGTCAGCCGCTTCCGC
CTTCGCCCATGACTTCTACGGACATATCATTCGTAAAGGGGAAGCGACAGAAACTGAACAAGTGAAAGCCGCGCGAATCG
CTTCAGTTGCGGTCGCCCTCGTCTCAATGGGACTAGCTTTTTTCGCCCAGTCGATGAACGTTGCGTTTCTTGTCTCGCTC
GCCTTCGCCGTTGCGGCGAGTGCGAACTTACCTGTGATTCTCTTTACGATTTTCTGGAGACGCTTTAATACAGGAGGCGC
CATTTGGGGAATGGTCGTCGGTTTGTTCTCCTCACTGATTCTAGTCGCACTCAGCCCGAACCTTTGGGCTCCGGACGGTT
CGGCCATCTTTGTCGGTGAAGCCCTTTTCCCACTATCCAATCCCGGGATTGTATCAATCCCTCTCGGTTTCATCGCTGCC
GTGATTGGTACACTGGTCACGAAATCGGATGAAGCAGCAGGAAACTATGAACGCGTCCTCGTCAAGGCGAACACTGGAAT
CGACGCGGAGACGGAAGTCGCCGCTACGAAAGCAGACTAA

Upstream 100 bases:

>100_bases
TTTCCCAGTTCATCATGACCTGGACACTTTGTGTACTTTATAGTCGACGTGCCCGTCGCTTTGACGCTCTCGTCGAACAA
TTAAAAAACGAGGTGAGATC

Downstream 100 bases:

>100_bases
ATAAAAAATGGAGTGGCTCAACGCCACTCCATTTTTACGTGATTGCGATTCGTTTATATTTTTGATACATGGCGATTCGC
CACGGGACAATCATCCCCCA

Product: SSS sodium solute transporter superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MNWTAIALFIAIVGLTLVITYFAARKTKTASDFYTADGGLTGFQNGLAIAGDYMSAASFLGIAGMIALAGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTMADMIAARFNKPRVRGVAAMNAIVISIFYMIAQLVGAGALIELLLGIPYTTSVVVVGI
LMTVYVVFGGMTATSWVQITKAVLLMIGTAIISFLVFARFDFSVTTMFNEVSKATPLGSDFLNPGNKFKLPLDTISLNMA
LVLGTAGLPHILIRFFTVKDAPTARQSVVYATWIIGAFYILTIFLGFGAAAFVGRDAILAANPAGNMAAPLLAQVLGGDL
LFAFVAAIAFATILAVVAGLVLSAASAFAHDFYGHIIRKGEATETEQVKAARIASVAVALVSMGLAFFAQSMNVAFLVSL
AFAVAASANLPVILFTIFWRRFNTGGAIWGMVVGLFSSLILVALSPNLWAPDGSAIFVGEALFPLSNPGIVSIPLGFIAA
VIGTLVTKSDEAAGNYERVLVKANTGIDAETEVAATKAD

Sequences:

>Translated_519_residues
MNWTAIALFIAIVGLTLVITYFAARKTKTASDFYTADGGLTGFQNGLAIAGDYMSAASFLGIAGMIALAGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTMADMIAARFNKPRVRGVAAMNAIVISIFYMIAQLVGAGALIELLLGIPYTTSVVVVGI
LMTVYVVFGGMTATSWVQITKAVLLMIGTAIISFLVFARFDFSVTTMFNEVSKATPLGSDFLNPGNKFKLPLDTISLNMA
LVLGTAGLPHILIRFFTVKDAPTARQSVVYATWIIGAFYILTIFLGFGAAAFVGRDAILAANPAGNMAAPLLAQVLGGDL
LFAFVAAIAFATILAVVAGLVLSAASAFAHDFYGHIIRKGEATETEQVKAARIASVAVALVSMGLAFFAQSMNVAFLVSL
AFAVAASANLPVILFTIFWRRFNTGGAIWGMVVGLFSSLILVALSPNLWAPDGSAIFVGEALFPLSNPGIVSIPLGFIAA
VIGTLVTKSDEAAGNYERVLVKANTGIDAETEVAATKAD
>Mature_519_residues
MNWTAIALFIAIVGLTLVITYFAARKTKTASDFYTADGGLTGFQNGLAIAGDYMSAASFLGIAGMIALAGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTMADMIAARFNKPRVRGVAAMNAIVISIFYMIAQLVGAGALIELLLGIPYTTSVVVVGI
LMTVYVVFGGMTATSWVQITKAVLLMIGTAIISFLVFARFDFSVTTMFNEVSKATPLGSDFLNPGNKFKLPLDTISLNMA
LVLGTAGLPHILIRFFTVKDAPTARQSVVYATWIIGAFYILTIFLGFGAAAFVGRDAILAANPAGNMAAPLLAQVLGGDL
LFAFVAAIAFATILAVVAGLVLSAASAFAHDFYGHIIRKGEATETEQVKAARIASVAVALVSMGLAFFAQSMNVAFLVSL
AFAVAASANLPVILFTIFWRRFNTGGAIWGMVVGLFSSLILVALSPNLWAPDGSAIFVGEALFPLSNPGIVSIPLGFIAA
VIGTLVTKSDEAAGNYERVLVKANTGIDAETEVAATKAD

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=449, Percent_Identity=22.71714922049, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1790503, Length=520, Percent_Identity=45.7692307692308, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1787251, Length=435, Percent_Identity=28.735632183908, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082237, Length=432, Percent_Identity=22.9166666666667, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54553; Mature: 54553

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWTAIALFIAIVGLTLVITYFAARKTKTASDFYTADGGLTGFQNGLAIAGDYMSAASFL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEEECHHHHHHHHH
GIAGMIALAGFDGFFYSIGFLVAYLVVLYLVAEPLRNLGKYTMADMIAARFNKPRVRGVA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AMNAIVISIFYMIAQLVGAGALIELLLGIPYTTSVVVVGILMTVYVVFGGMTATSWVQIT
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAVLLMIGTAIISFLVFARFDFSVTTMFNEVSKATPLGSDFLNPGNKFKLPLDTISLNMA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHCCCCCCEECCHHHHHHHHH
LVLGTAGLPHILIRFFTVKDAPTARQSVVYATWIIGAFYILTIFLGFGAAAFVGRDAILA
EEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ANPAGNMAAPLLAQVLGGDLLFAFVAAIAFATILAVVAGLVLSAASAFAHDFYGHIIRKG
ECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EATETEQVKAARIASVAVALVSMGLAFFAQSMNVAFLVSLAFAVAASANLPVILFTIFWR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
RFNTGGAIWGMVVGLFSSLILVALSPNLWAPDGSAIFVGEALFPLSNPGIVSIPLGFIAA
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECEECCCCCCCEEEECHHHHHH
VIGTLVTKSDEAAGNYERVLVKANTGIDAETEVAATKAD
HHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNWTAIALFIAIVGLTLVITYFAARKTKTASDFYTADGGLTGFQNGLAIAGDYMSAASFL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCEEECHHHHHHHHH
GIAGMIALAGFDGFFYSIGFLVAYLVVLYLVAEPLRNLGKYTMADMIAARFNKPRVRGVA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AMNAIVISIFYMIAQLVGAGALIELLLGIPYTTSVVVVGILMTVYVVFGGMTATSWVQIT
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAVLLMIGTAIISFLVFARFDFSVTTMFNEVSKATPLGSDFLNPGNKFKLPLDTISLNMA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHCCCCCCEECCHHHHHHHHH
LVLGTAGLPHILIRFFTVKDAPTARQSVVYATWIIGAFYILTIFLGFGAAAFVGRDAILA
EEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ANPAGNMAAPLLAQVLGGDLLFAFVAAIAFATILAVVAGLVLSAASAFAHDFYGHIIRKG
ECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EATETEQVKAARIASVAVALVSMGLAFFAQSMNVAFLVSLAFAVAASANLPVILFTIFWR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
RFNTGGAIWGMVVGLFSSLILVALSPNLWAPDGSAIFVGEALFPLSNPGIVSIPLGFIAA
HHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECEECCCCCCCEEEECHHHHHH
VIGTLVTKSDEAAGNYERVLVKANTGIDAETEVAATKAD
HHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]