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The map label for this gene is ina [H]

Identifier: 229915916

GI number: 229915916

Start: 159550

End: 161943

Strand: Reverse

Name: ina [H]

Synonym: EAT1b_0184

Alternate gene names: 229915916

Gene position: 161943-159550 (Counterclockwise)

Preceding gene: 229915917

Following gene: 229915915

Centisome position: 5.4

GC content: 48.79

Gene sequence:

>2394_bases
ATGAAAAAACGTTCCATCCGTCGAACGACACTCGCGGCTCTCATGACATCTGCCATGACAGTCAGTATCGTTCCGGCAGC
TGGTGCTGCACCCCTCTCGGTTGCACCATCGGTTCCGACAACGAGCGAGCTCGCTCCATTCGACCACAACATCATCGATG
AAGAGCGTCTCGCGAAAGCTCTCGAGAAACGTGGCGTCATCAAAAAAGGATTGTCCGCATCTGAACGCATGAAAGCAGTC
GATGCGTATATCGCGAAAAAACAAGGTGAAGCGAAAGATCCACATAAGCACGACGACAAAGTGAACGAGAAGGCTTCGAA
AGCAAAAGAGAAGATACATACTCAATTCGAAAAGGAATCAAAACGAATTCTTGATAAAGCGAAAAAAGGGCAAGGAAATT
ACCGTAAAGGGAAACCGAACGGTCAAGTAAAAGTATCTCCTGCCCAGCAATCTGCATACAATGGTTCGGTACGTGAAGAT
AAAGTCCTCGTTCTCCTCGTCGAGTACAGCGACTTCAAACACAATAACATCATCCAAGAGCCGGGCTATATGTACAGCGA
TAACTTCAGTAAAGAACATTACGAAAAGTATATGTTCGGTGATCAACAATTTGAACTCTTTAACGGTGAAAAGGTTCAAA
CGTTCAAACAATACTATGAAGAACAATCAGGCGGAAGTTATACGGTCGATGGTGAGGTTTCGGAGTGGTTGACCGTTCCG
GGAACCGCGAAAGACTATGGAGCTGACAAAGGTGATGGCGGACATGATAACGTCGGACCAGGACCACGTCAACTCGTCAA
AGATGCGTTGAATGCTGCGGTCGCATCTGGAATCGATTTGAAAGAACATGATCAATACGACCTTTACGATTTGGATGGAG
ACGGTGACTTCAATGAGCCGGACGGTCTCGTTGACCACTTGATGATCATCCACGCTGGGACTGGTCAAGAAGCGGGTGGC
GGTGCGCTCGGTGACGATGCGGTATGGTCACATCGCTGGGTTCTTAACGGTGTTTATCCAGTAGCCAACACAGAAGCTGC
AGTTCCTTACTGGGGTGGGAAAATGGCTGCATATGATTACACGATTCAACCTGAAGATGGTGCGGTCGGCGTTTTCGCAC
ACGAGTTCGGACATGACCTCGGTCTTCCAGATGAGTACGATACGCAGTACACAGGTCAAGGTGAGCCGGTACAATCATGG
TCGATCATGAGTGGCGGTAGCTGGGCTGGTAAAGTCGCTGGTACGGAGCCAACAAGCTTCTCACCACAAAACAAAGAATA
CTTCCAAAAAATCATGGGTGGAAACTGGGCAAACATCACAGAAGTCGACCTTGAAGACATCAACTCCCAAGGGTTCGTCG
CACAACTCGACCAATCTGTGACGAAATCAAACAACCCAGGCATCGTCAAAGTCAACCTTCCTGATAAGAAGATTAAAGGA
ATCGAACCAGCTTATGGCGATCGCTACTATTACTCGACAAAAGGTGACGACATCCATACTGAGATGGCAACACCAGCTGT
GAAACTCGGTGCGGACGGAGTCCTCGCATTCGATTCATTCTATGAAGTCGAATCGGACTATGATTACTTGTACATCAAAG
CCCTCAGTGGTGGTCAAGAAGTCGTTCTCGATGTATTCGGTGACGACGTCAACGGCGCAAACGAAGCAGGCTACCCTGCT
GAGACGACGAACGGTGCATGGGTCAACAAATCATACGACCTCTCACAATTCGCTGGACAAGATGTTCAAATCGTCTTTGA
ATACGTGACAGACGGCGGTGTCGCTATGAAAGGCTTCGCAGTCGACAACTTGTCAATCAAATCAGAATCAGCAACACTCT
TCGCAGATGATGCGGAAGGCGCTGAAGCCGTGACGCTCGATGGATTCGTCTCTTCAGACGGATACGATTCAAAACCACAC
TATTACTACCTTGAGTGGCGTAACCACGCCGGGTCGGATATGGGTCTTCTCAACGGCCGCGGCGTGAAATATAACACTGG
TCTTGTCGTTTGGTATGGTGATGACTCGTTCACAGACAACTGGGTCGGTGTCCACCCTGGTGAAGGCTTCCTCGGTGTCG
TCGATTCACATCCTGAAGCGCTCATCGGTAACTTGAACGGTCAACAGACAGTCGCAGGTAGTACACGTTACCAAATTGCT
GATGCGGCGTTCAGTCTCGATAAGACGCTCGCTTGGTATATCGATTCACCGAGTCGTGGCGTGTACGATTACAAAGCACA
GCCTGGCGTGAAGCAGTTCAATGATGCAAACTCTTACATCAACTCGCTTATTCCAGATGCAGGACGCAAACTTCCGCAAT
ACGGTCTCGTCATTGACGTAGTCGGTGAAGCGAAAGACAACTCTGCAGGTGCCGTTTGGATCCGTACAAAATAA

Upstream 100 bases:

>100_bases
TTTATTATTTTCTGAATATTGACATTAATCAGACACAAAGAGTACATTTACAACAAGCTCACACATTTTCCCATTATTTT
TTAACAGGAGGTTCACACAA

Downstream 100 bases:

>100_bases
TGATGTAGCATTCGACCTCCAGTCTTCCTTTATCGAAGATTGGAGGTCTTATTATTCTAAAAAAGCTTGAAAACGACGAA
TAATCTGTGTAACATAGTTG

Product: M6 family metalloprotease domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MKKRSIRRTTLAALMTSAMTVSIVPAAGAAPLSVAPSVPTTSELAPFDHNIIDEERLAKALEKRGVIKKGLSASERMKAV
DAYIAKKQGEAKDPHKHDDKVNEKASKAKEKIHTQFEKESKRILDKAKKGQGNYRKGKPNGQVKVSPAQQSAYNGSVRED
KVLVLLVEYSDFKHNNIIQEPGYMYSDNFSKEHYEKYMFGDQQFELFNGEKVQTFKQYYEEQSGGSYTVDGEVSEWLTVP
GTAKDYGADKGDGGHDNVGPGPRQLVKDALNAAVASGIDLKEHDQYDLYDLDGDGDFNEPDGLVDHLMIIHAGTGQEAGG
GALGDDAVWSHRWVLNGVYPVANTEAAVPYWGGKMAAYDYTIQPEDGAVGVFAHEFGHDLGLPDEYDTQYTGQGEPVQSW
SIMSGGSWAGKVAGTEPTSFSPQNKEYFQKIMGGNWANITEVDLEDINSQGFVAQLDQSVTKSNNPGIVKVNLPDKKIKG
IEPAYGDRYYYSTKGDDIHTEMATPAVKLGADGVLAFDSFYEVESDYDYLYIKALSGGQEVVLDVFGDDVNGANEAGYPA
ETTNGAWVNKSYDLSQFAGQDVQIVFEYVTDGGVAMKGFAVDNLSIKSESATLFADDAEGAEAVTLDGFVSSDGYDSKPH
YYYLEWRNHAGSDMGLLNGRGVKYNTGLVVWYGDDSFTDNWVGVHPGEGFLGVVDSHPEALIGNLNGQQTVAGSTRYQIA
DAAFSLDKTLAWYIDSPSRGVYDYKAQPGVKQFNDANSYINSLIPDAGRKLPQYGLVIDVVGEAKDNSAGAVWIRTK

Sequences:

>Translated_797_residues
MKKRSIRRTTLAALMTSAMTVSIVPAAGAAPLSVAPSVPTTSELAPFDHNIIDEERLAKALEKRGVIKKGLSASERMKAV
DAYIAKKQGEAKDPHKHDDKVNEKASKAKEKIHTQFEKESKRILDKAKKGQGNYRKGKPNGQVKVSPAQQSAYNGSVRED
KVLVLLVEYSDFKHNNIIQEPGYMYSDNFSKEHYEKYMFGDQQFELFNGEKVQTFKQYYEEQSGGSYTVDGEVSEWLTVP
GTAKDYGADKGDGGHDNVGPGPRQLVKDALNAAVASGIDLKEHDQYDLYDLDGDGDFNEPDGLVDHLMIIHAGTGQEAGG
GALGDDAVWSHRWVLNGVYPVANTEAAVPYWGGKMAAYDYTIQPEDGAVGVFAHEFGHDLGLPDEYDTQYTGQGEPVQSW
SIMSGGSWAGKVAGTEPTSFSPQNKEYFQKIMGGNWANITEVDLEDINSQGFVAQLDQSVTKSNNPGIVKVNLPDKKIKG
IEPAYGDRYYYSTKGDDIHTEMATPAVKLGADGVLAFDSFYEVESDYDYLYIKALSGGQEVVLDVFGDDVNGANEAGYPA
ETTNGAWVNKSYDLSQFAGQDVQIVFEYVTDGGVAMKGFAVDNLSIKSESATLFADDAEGAEAVTLDGFVSSDGYDSKPH
YYYLEWRNHAGSDMGLLNGRGVKYNTGLVVWYGDDSFTDNWVGVHPGEGFLGVVDSHPEALIGNLNGQQTVAGSTRYQIA
DAAFSLDKTLAWYIDSPSRGVYDYKAQPGVKQFNDANSYINSLIPDAGRKLPQYGLVIDVVGEAKDNSAGAVWIRTK
>Mature_797_residues
MKKRSIRRTTLAALMTSAMTVSIVPAAGAAPLSVAPSVPTTSELAPFDHNIIDEERLAKALEKRGVIKKGLSASERMKAV
DAYIAKKQGEAKDPHKHDDKVNEKASKAKEKIHTQFEKESKRILDKAKKGQGNYRKGKPNGQVKVSPAQQSAYNGSVRED
KVLVLLVEYSDFKHNNIIQEPGYMYSDNFSKEHYEKYMFGDQQFELFNGEKVQTFKQYYEEQSGGSYTVDGEVSEWLTVP
GTAKDYGADKGDGGHDNVGPGPRQLVKDALNAAVASGIDLKEHDQYDLYDLDGDGDFNEPDGLVDHLMIIHAGTGQEAGG
GALGDDAVWSHRWVLNGVYPVANTEAAVPYWGGKMAAYDYTIQPEDGAVGVFAHEFGHDLGLPDEYDTQYTGQGEPVQSW
SIMSGGSWAGKVAGTEPTSFSPQNKEYFQKIMGGNWANITEVDLEDINSQGFVAQLDQSVTKSNNPGIVKVNLPDKKIKG
IEPAYGDRYYYSTKGDDIHTEMATPAVKLGADGVLAFDSFYEVESDYDYLYIKALSGGQEVVLDVFGDDVNGANEAGYPA
ETTNGAWVNKSYDLSQFAGQDVQIVFEYVTDGGVAMKGFAVDNLSIKSESATLFADDAEGAEAVTLDGFVSSDGYDSKPH
YYYLEWRNHAGSDMGLLNGRGVKYNTGLVVWYGDDSFTDNWVGVHPGEGFLGVVDSHPEALIGNLNGQQTVAGSTRYQIA
DAAFSLDKTLAWYIDSPSRGVYDYKAQPGVKQFNDANSYINSLIPDAGRKLPQYGLVIDVVGEAKDNSAGAVWIRTK

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 86906; Mature: 86906

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRSIRRTTLAALMTSAMTVSIVPAAGAAPLSVAPSVPTTSELAPFDHNIIDEERLAKA
CCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LEKRGVIKKGLSASERMKAVDAYIAKKQGEAKDPHKHDDKVNEKASKAKEKIHTQFEKES
HHHCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KRILDKAKKGQGNYRKGKPNGQVKVSPAQQSAYNGSVREDKVLVLLVEYSDFKHNNIIQE
HHHHHHHHCCCCCCCCCCCCCCEEECCCHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCC
PGYMYSDNFSKEHYEKYMFGDQQFELFNGEKVQTFKQYYEEQSGGSYTVDGEVSEWLTVP
CCCEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEECCCCHHEEECC
GTAKDYGADKGDGGHDNVGPGPRQLVKDALNAAVASGIDLKEHDQYDLYDLDGDGDFNEP
CCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCC
DGLVDHLMIIHAGTGQEAGGGALGDDAVWSHRWVLNGVYPVANTEAAVPYWGGKMAAYDY
CHHHEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECEEECCCCCCCCCCCCCEEEEEEE
TIQPEDGAVGVFAHEFGHDLGLPDEYDTQYTGQGEPVQSWSIMSGGSWAGKVAGTEPTSF
EECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
SPQNKEYFQKIMGGNWANITEVDLEDINSQGFVAQLDQSVTKSNNPGIVKVNLPDKKIKG
CCCCHHHHHHHHCCCCCCEEEEHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHCC
IEPAYGDRYYYSTKGDDIHTEMATPAVKLGADGVLAFDSFYEVESDYDYLYIKALSGGQE
CCCCCCCEEEEECCCCCEEHHHCCCEEEECCCCEEEEHHHHCCCCCCCEEEEEEECCCCE
VVLDVFGDDVNGANEAGYPAETTNGAWVNKSYDLSQFAGQDVQIVFEYVTDGGVAMKGFA
EEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCHHHHCCCCEEEEEEECCCCCEEEEEEE
VDNLSIKSESATLFADDAEGAEAVTLDGFVSSDGYDSKPHYYYLEWRNHAGSDMGLLNGR
ECCEEEECCCCEEEECCCCCCCEEEECCEECCCCCCCCCCEEEEEECCCCCCCCEEECCC
GVKYNTGLVVWYGDDSFTDNWVGVHPGEGFLGVVDSHPEALIGNLNGQQTVAGSTRYQIA
CEEEECCEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCEEECCCCCEEECCCCEEEEH
DAAFSLDKTLAWYIDSPSRGVYDYKAQPGVKQFNDANSYINSLIPDAGRKLPQYGLVIDV
HHHHHCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
VGEAKDNSAGAVWIRTK
ECCCCCCCCCEEEEEEC
>Mature Secondary Structure
MKKRSIRRTTLAALMTSAMTVSIVPAAGAAPLSVAPSVPTTSELAPFDHNIIDEERLAKA
CCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LEKRGVIKKGLSASERMKAVDAYIAKKQGEAKDPHKHDDKVNEKASKAKEKIHTQFEKES
HHHCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KRILDKAKKGQGNYRKGKPNGQVKVSPAQQSAYNGSVREDKVLVLLVEYSDFKHNNIIQE
HHHHHHHHCCCCCCCCCCCCCCEEECCCHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCC
PGYMYSDNFSKEHYEKYMFGDQQFELFNGEKVQTFKQYYEEQSGGSYTVDGEVSEWLTVP
CCCEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCEEECCCCHHEEECC
GTAKDYGADKGDGGHDNVGPGPRQLVKDALNAAVASGIDLKEHDQYDLYDLDGDGDFNEP
CCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCC
DGLVDHLMIIHAGTGQEAGGGALGDDAVWSHRWVLNGVYPVANTEAAVPYWGGKMAAYDY
CHHHEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECEEECCCCCCCCCCCCCEEEEEEE
TIQPEDGAVGVFAHEFGHDLGLPDEYDTQYTGQGEPVQSWSIMSGGSWAGKVAGTEPTSF
EECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
SPQNKEYFQKIMGGNWANITEVDLEDINSQGFVAQLDQSVTKSNNPGIVKVNLPDKKIKG
CCCCHHHHHHHHCCCCCCEEEEHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHCC
IEPAYGDRYYYSTKGDDIHTEMATPAVKLGADGVLAFDSFYEVESDYDYLYIKALSGGQE
CCCCCCCEEEEECCCCCEEHHHCCCEEEECCCCEEEEHHHHCCCCCCCEEEEEEECCCCE
VVLDVFGDDVNGANEAGYPAETTNGAWVNKSYDLSQFAGQDVQIVFEYVTDGGVAMKGFA
EEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCHHHHCCCCEEEEEEECCCCCEEEEEEE
VDNLSIKSESATLFADDAEGAEAVTLDGFVSSDGYDSKPHYYYLEWRNHAGSDMGLLNGR
ECCEEEECCCCEEEECCCCCCCEEEECCEECCCCCCCCCCEEEEEECCCCCCCCEEECCC
GVKYNTGLVVWYGDDSFTDNWVGVHPGEGFLGVVDSHPEALIGNLNGQQTVAGSTRYQIA
CEEEECCEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCEEECCCCCEEECCCCEEEEH
DAAFSLDKTLAWYIDSPSRGVYDYKAQPGVKQFNDANSYINSLIPDAGRKLPQYGLVIDV
HHHHHCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEEE
VGEAKDNSAGAVWIRTK
ECCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]